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- | veliparib (ABT-888) / AbbVie, Yonsa (abiraterone acetate) / Churchill Pharma, Sun Pharma
New P2 trial, PARP Biomarker, Metastases: Abiraterone Acetate and Prednisone With or Without Veliparib in Treating Patients With Metastatic Castration-Resistant Prostate Cancer (clinicaltrials.gov) - Apr 10, 2012
P2, N=148, Recruiting, Sponsor: National Cancer Institute (NCI)
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- | dexamethasone / Generic mfg., pomalidomide / Generic mfg.
Combination therapy: Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (clinicaltrials.gov) - Apr 10, 2012
P1, N=30, Recruiting, Sponsor: Celgene Corporation
- |||| bortezomib / Generic mfg., pomalidomide / Generic mfg.
Clinical: Pomalidomide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov) - Apr 10, 2012
P1/2, N=61, Recruiting, Sponsor: Mayo Clinic
. Not yet recruiting --> Recruiting
- | Nplate (romiplostim) / Amgen, Kyowa Kirin
Enrollment change: Study of AMG 531 to Evaluate the Safety & Efficacy in Patients With Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Apr 9, 2012
P1/2, N=50, Completed, Sponsor: M.D. Anderson Cancer Center
Not yet recruiting --> Recruiting N=36 --> 50
- || prednisolone / Generic mfg.
New P3 trial: Prednisolone in Infantile Spasms- High Dose Versus Usual Dose (clinicaltrials.gov) - Apr 9, 2012
P3, N=63, Completed, Sponsor: Lady Hardinge Medical College
- | Nplate (romiplostim) / Amgen, Kyowa Kirin
Trial completion: Study of AMG 531 to Evaluate the Safety & Efficacy in Patients With Non-Hodgkin's Lymphoma (clinicaltrials.gov) - Apr 9, 2012
P1/2, N=50, Completed, Sponsor: M.D. Anderson Cancer Center
N=36 --> 50 Active, not recruiting --> Completed
- ||||||| Trial completion, Metastases: ET743-OVA-301: An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer (clinicaltrials.gov) - Apr 9, 2012
P3, N=672, Completed, Sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- hydrocortisone / Generic mfg.
New P2 trial: Glucocorticoid Treatment for Social Phobia (clinicaltrials.gov) - Apr 8, 2012
P2, N=66, Terminated, Sponsor: University Hospital Inselspital, Berne
- |||| Zolinza (vorinostat) / Merck (MSD)
Trial completion, Combination therapy, Epigenetic controller: Study of Vorinostat (MK0683), an Histone Deacetylase (HDAC) Inhibitor in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (MK-0683-095) (clinicaltrials.gov) - Apr 8, 2012
P2, N=143, Completed, Sponsor: Merck Sharp & Dohme Corp.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| Incruse Ellipta (umeclidinium) / GSK, Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
New P2 trial, Combination therapy: Evaluate the Safety, Efficacy and Dose Response of GSK573719 in Combination With Fluticasone Furoate in Subjects With Asthma (clinicaltrials.gov) - Apr 5, 2012
P2, N=421, Completed, Sponsor: GlaxoSmithKline
- Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
Enrollment change: Bioequivalence Study to Compare Fluticasone Furoate (FF) 1-strip Inhaler With FF 2-strip Inhaler and With FF/Vilanterol Combination (clinicaltrials.gov) - Apr 4, 2012
P1, N=30, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed N=24 --> 30
- Decadron (dexamethasone) / Merck (MSD)
Enrollment change, Surgery: Post Operative Sore Throat and Dexamethasone (clinicaltrials.gov) - Apr 4, 2012
P4, N=120, Completed, Sponsor: Northwestern University
N=24 --> 30 N=70 --> 120
- dexamethasone / Generic mfg., lenalidomide / Generic mfg., carfilzomib / Generic mfg.
Clinical: Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma (clinicaltrials.gov) - Apr 4, 2012
P2, N=30, Recruiting, Sponsor: National Cancer Institute (NCI)
- | Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
Trial completion: Bioequivalence Study to Compare Fluticasone Furoate (FF) 1-strip Inhaler With FF 2-strip Inhaler and With FF/Vilanterol Combination (clinicaltrials.gov) - Apr 4, 2012
P1, N=30, Completed, Sponsor: GlaxoSmithKline
N=70 --> 120 Not yet recruiting --> Completed
- || triamcinolone acetonide / Generic mfg.
New P3 trial: Treatment Study of Frozen Shoulder: Corticosteroid Injection in Joint Versus Wait and See Policy (clinicaltrials.gov) - Apr 2, 2012
P3, N=120, Active, not recruiting, Sponsor: Satya Pal Sharma
- | methylprednisolone acetate / Generic mfg.
Clinical: Steroid Injection Treatment of Carpal Tunnel Syndrome (clinicaltrials.gov) - Apr 2, 2012
P2/3, N=112, Completed, Sponsor: Region Skane
Not yet recruiting --> Completed Recruiting --> Completed
- dexamethasone injection / Generic mfg.
Clinical: Transforaminal Epidural Steroid Injection to Treat Hemiplegic Shoulder Pain (clinicaltrials.gov) - Apr 2, 2012
P=N/A, N=20, Recruiting, Sponsor: University of Sao Paulo General Hospital
- |||||||||| beclometasone/formoterol / Generic mfg., fluticasone / Generic mfg., fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
New P3 trial: A Study in Patients With Asthma (clinicaltrials.gov) - Apr 2, 2012
P3, N=90, Active, not recruiting, Sponsor: Chiesi Farmaceutici S.p.A.
- ||| lenalidomide / Generic mfg., thalidomide / Generic mfg.
Enrollment closed: Lenalidomide, Thalidomide and Dexamethasone in Treating Participants With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov) - Apr 2, 2012
P1/2, N=64, Active, not recruiting, Sponsor: M.D. Anderson Cancer Center
Recruiting --> Completed Recruiting --> Active, not recruiting
- ||||||| Breo Ellipta (fluticasone furoate / vilanterol) / GSK, Innoviva
Trial completion: A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD) (clinicaltrials.gov) - Apr 2, 2012
P3, N=1626, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||||||| fluticasone / Generic mfg., fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Trial completion: A Study in Patients With Chronic Obstructive Pulmonary Disease (clinicaltrials.gov) - Apr 1, 2012
P3, N=373, Completed, Sponsor: Chiesi Farmaceutici S.p.A.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- dexamethasone / Generic mfg., lenalidomide / Generic mfg.
Trial initiation date: Pilot Study to Establish Safety & Efficacy of a Combination of Dexamethasone and Lenalidomide in Patients With Relapsed or Refractory Chronic Lymphocytic Leukaemia (CLL) (clinicaltrials.gov) - Apr 1, 2012
P2, N=24, Recruiting, Sponsor: University College, London
Active, not recruiting --> Completed Initiation date: Jan 2012 --> May 2012
- || AZD5423 / AstraZeneca
Enrollment change: Safety, Pharmacokinetics and Pharmacodynamics After Single and Multiple Dosing of AZD5423 in Japanese Healthy Male Subjects (clinicaltrials.gov) - Apr 1, 2012
P1, N=96, Completed, Sponsor: AstraZeneca
Initiation date: Jan 2012 --> May 2012 N=40 --> 96
- TroVax (MVA 5T4) / Oxford Biomedica
New P2 trial: SKOPOS: A Phase II Trial to Assess TroVax (clinicaltrials.gov) - Apr 1, 2012
P2, N=26, Recruiting, Sponsor: Wales Cancer Trials Unit
- | Adcetris (brentuximab vedotin) / Seagen, Takeda, Matulane (procarbazine hydrochloride) / Leadiant Biosci
New P2 trial, Metastases: Targeted BEACOPP Variants in Patients With Newly Diagnosed Advanced Classical Hodgkin Lymphoma (clinicaltrials.gov) - Apr 1, 2012
P2, N=100, Recruiting, Sponsor: University of Cologne
- ||| AZD5423 / AstraZeneca
Trial completion: Safety, Pharmacokinetics and Pharmacodynamics After Single and Multiple Dosing of AZD5423 in Japanese Healthy Male Subjects (clinicaltrials.gov) - Apr 1, 2012
P1, N=96, Completed, Sponsor: AstraZeneca
N=40 --> 96 Suspended --> Completed
- carboplatin / Generic mfg., docetaxel / Generic mfg.
Enrollment change: A Phase II Study of Docetaxel Plus Carboplatin in Chemonaive Hormone-Refractory Prostate Cancer (HRPC) Patients (clinicaltrials.gov) - Mar 29, 2012
P2, N=2, Completed, Sponsor: National University Hospital, Singapore
Suspended --> Completed N=29 --> 2
- |||||||||| bortezomib / Generic mfg., dexamethasone / Generic mfg., carfilzomib / Generic mfg.
P3 data: ENDEAVOR: Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients (clinicaltrials.gov) - Mar 29, 2012
P3, N=888, Recruiting, Sponsor: Onyx Pharmaceuticals
- | dexamethasone / Generic mfg., pomalidomide / Generic mfg.
Combination therapy: Japanese Phase 1 Study to Evaluate Tolerated Dose, Safety, and Efficacy of Pomalidomide in Patients With Refractory or Relapsed and Refractory Multiple Myeloma (clinicaltrials.gov) - Mar 29, 2012
P1, N=12, Active, not recruiting, Sponsor: Celgene Corporation
- carboplatin / Generic mfg., docetaxel / Generic mfg.
Trial completion: A Phase II Study of Docetaxel Plus Carboplatin in Chemonaive Hormone-Refractory Prostate Cancer (HRPC) Patients (clinicaltrials.gov) - Mar 29, 2012
P2, N=2, Completed, Sponsor: National University Hospital, Singapore
N=29 --> 2 Recruiting --> Completed
- Dulera (mometasone/formoterol) / Merck (MSD), Novartis
New P3 trial: Study of Mometasone Furoate/Formoterol Fumarate (MF/F) Metered Dose Inhaler (MDI) in Adolescents & Adults With Persistent Asthma (P08212) (clinicaltrials.gov) - Mar 27, 2012
P3, N=49, Completed, Sponsor: Merck
- bortezomib / Generic mfg., dexamethasone / Generic mfg., bendamustine / Generic mfg.
Enrollment closed: BVD: Study of Bendamustine, Velcade and Dexamethasone in the Treatment of Elderly Patients With Multiple Myeloma (clinicaltrials.gov) - Mar 27, 2012
P2, N=70, Active, not recruiting, Sponsor: Intergroupe Francophone du Myelome
Recruiting --> Completed Recruiting --> Active, not recruiting
- |||||||||| Ninlaro (ixazomib) / Takeda
New P3 trial: TOURMALINE-MM1: A Phase 3 Study Comparing Oral Ixazomib Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (clinicaltrials.gov) - Mar 26, 2012
P3, N=703, Recruiting, Sponsor: Millennium Pharmaceuticals, Inc.
- | fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
New P1 trial: Phase I Pharmacokinetic Study (SALBLOCK) (clinicaltrials.gov) - Mar 25, 2012
P1, N=20, Completed, Sponsor: Orion Corporation, Orion Pharma
- ||||| Veramyst (fluticasone furoate nasal spray) / GSK
New P2 trial: A Dose-ranging Study of Fluticasone Furoate (FF) (clinicaltrials.gov) - Mar 22, 2012
P2, N=575, Recruiting, Sponsor: GlaxoSmithKline
- ||| fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Enrollment change: SERETIDE 100/50 bd (Twice Daily) Versus FLIXOTIDE 100 bd As Initial Maintenance Therapy In Moderate Asthma In Adults (clinicaltrials.gov) - Mar 21, 2012
P4, N=81, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting N=310 --> 81
- Veramyst (fluticasone furoate nasal spray) / GSK
Clinical: Effect of Intranasal Corticosteroids on Pulmonary Symptoms in Asthmatics With Nasal Congestion (clinicaltrials.gov) - Mar 21, 2012
P=N/A, N=60, Recruiting, Sponsor: St. Olavs Hospital
- |||| Dulera (mometasone/formoterol) / Merck (MSD), Novartis
Enrollment open, Monotherapy: SPIRO: A Serious Asthma Outcome Study With Mometasone Furoate/Formoterol Versus Mometasone Furoate in Asthmatics 12 Years and Over (P06241) (clinicaltrials.gov) - Mar 21, 2012
P4, N=11664, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
N=310 --> 81 Not yet recruiting --> Recruiting
- Avastin (bevacizumab) / Roche
Trial termination: EBEV: Efficacy, Safety and Tolerability of Repeated Dosis of Intravitreous Bevacizumab in Uveitic Macular Oedema (clinicaltrials.gov) - Mar 21, 2012
P3, N=5, Terminated, Sponsor: Hospital Clinic of Barcelona
Recruiting --> Terminated; New intraocular steroid in the market. Recruitment no longer ethical.
- Avastin (bevacizumab) / Roche
Enrollment change: EBEV: Efficacy, Safety and Tolerability of Repeated Dosis of Intravitreous Bevacizumab in Uveitic Macular Oedema (clinicaltrials.gov) - Mar 21, 2012
P3, N=5, Terminated, Sponsor: Hospital Clinic of Barcelona
Recruitment no longer ethical. N=60 --> 5
- Winrevair (sotatercept-csrk) / BMS, Merck (MSD)
Combination therapy: Sotatercept (ACE-011) With Lenalidomide or Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma (clinicaltrials.gov) - Mar 21, 2012
P1, N=34, Recruiting, Sponsor: Massachusetts General Hospital
- budesonide/formoterol / Generic mfg.
New P2 trial: Inhaled BUDESONIDE/FORMOTEROL in Bronchiolitis Obliterans Following Stem Cell Transplantation (clinicaltrials.gov) - Mar 20, 2012
P2, N=32, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
- cytarabine / Generic mfg.
Trial withdrawal: Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia (clinicaltrials.gov) - Mar 20, 2012
P3, N=0, Withdrawn, Sponsor: National Institutes of Health Clinical Center (CC)
N=60 --> 5 Active, not recruiting --> Withdrawn
- cytarabine / Generic mfg.
Enrollment change: Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia (clinicaltrials.gov) - Mar 20, 2012
P3, N=0, Withdrawn, Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Withdrawn N=1100 --> 0
- methylprednisolone acetate / Generic mfg.
Trial completion: Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain (clinicaltrials.gov) - Mar 20, 2012
P0, N=240, Completed, Sponsor: Pain Management Center of Paducah
N=1100 --> 0 Active, not recruiting --> Completed
- methylprednisolone oral / Generic mfg.
Clinical: Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING Low Dose Study) (clinicaltrials.gov) - Mar 19, 2012
P=N/A, N=1300, Recruiting, Sponsor: The George Institute
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ||||| Decadron (dexamethasone) / Merck (MSD)
Clinical: Carfilzomib, Clarithromycin (Biaxin®), Lenalidomide (Revlimid®), and Dexamethasone (Decadron®) [Car-BiRD] Therapy for Subjects With Multiple Myeloma (clinicaltrials.gov) - Mar 19, 2012
P2, N=57, Recruiting, Sponsor: Weill Medical College of Cornell University
- ondansetron intravenous / Generic mfg., dexamethasone injection / Generic mfg., palonosetron intravenous / Generic mfg.
Trial initiation date: Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients (clinicaltrials.gov) - Mar 18, 2012
P2, N=85, Recruiting, Sponsor: Northside Hospital, Inc.
Not yet recruiting --> Recruiting Initiation date: Jul 2011 --> Feb 2012
- ondansetron intravenous / Generic mfg., dexamethasone injection / Generic mfg., palonosetron intravenous / Generic mfg.
Enrollment open: Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients (clinicaltrials.gov) - Mar 18, 2012
P2, N=85, Recruiting, Sponsor: Northside Hospital, Inc.
Initiation date: Jul 2011 --> Feb 2012 Not yet recruiting --> Recruiting
- budesonide / Generic mfg.
Trial termination: Budesonide Versus Placebo for the Treatment of Lymphocytic Colitis (clinicaltrials.gov) - Mar 15, 2012
P2/3, N=16, Terminated, Sponsor: Mayo Clinic
Not yet recruiting --> Recruiting Completed --> Terminated; Study closed early, because of low enrollment.