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- fluticasone / Generic mfg.
Enrollment change: Azelastine Fluticasone Combination vs. Fluticasone (clinicaltrials.gov) - Jun 10, 2012
P4, N=0, Withdrawn, Sponsor: University of Dundee
N=20 --> 0
- QVAR (beclomethasone dipropionate hydrofluoroalkane inhalation) / Teva
Enrollment change: PAW01: Additive Effects of QVAR to (Seretide) on Surrogate Markers of Airway Inflammation in Refractory Asthma (clinicaltrials.gov) - Jun 10, 2012
P4, N=15, Completed, Sponsor: University of Dundee
N=20 --> 0 N=24 --> 15
- QVAR (beclomethasone dipropionate hydrofluoroalkane inhalation) / Teva
Enrollment open: Beta Blocker Therapy in Mild to Moderate Asthmatics (clinicaltrials.gov) - Jun 10, 2012
P2, N=16, Recruiting, Sponsor: University of Dundee
N=24 --> 15 Not yet recruiting --> Recruiting
- Trial completion: Does Extra-fine Hydrofluoroalkane-beclomethasone Dipropionate (HFA-BDP) Suppress Small Airways Inflammation in Chronic Obstructive Pulmonary Disease (COPD)? (clinicaltrials.gov) - Jun 10, 2012
P4, N=16, Completed, Sponsor: University of Dundee
Not yet recruiting --> Recruiting Recruiting --> Completed
- QVAR (beclomethasone dipropionate hydrofluoroalkane inhalation) / Teva
Trial completion: PAW01: Additive Effects of QVAR to (Seretide) on Surrogate Markers of Airway Inflammation in Refractory Asthma (clinicaltrials.gov) - Jun 10, 2012
P4, N=15, Completed, Sponsor: University of Dundee
Recruiting --> Completed Recruiting --> Completed
- hydrocortisone / Generic mfg., propranolol / Generic mfg.
Enrollment change: Reversal of Acute β-Blocker Induced Bronchoconstriction (clinicaltrials.gov) - Jun 7, 2012
P4, N=14, Completed, Sponsor: University of Dundee
Recruiting --> Completed N=20 --> 14
- Nasonex (mometasone furoate nasal spray) / Merck (MSD)
Biomarker, New P4 trial, IO biomarker: MERK2: An Open-label Study to Identify Molecular Markers of Steroid Resistance (clinicaltrials.gov) - Jun 7, 2012
P4, N=24, Recruiting, Sponsor: Massachusetts General Hospital
- Dulera (mometasone/formoterol) / Merck (MSD), Novartis
New P2 trial: Study of the Effect of Mometasone Furoate/Formoterol (MF/F), Montelukast and Beclomethasone Dipropionate (BDP) on Plasma Cortisol Levels of Children 5-11 Years Old With Persistent Asthma (P05574) (clinicaltrials.gov) - Jun 7, 2012
P2, N=0, Withdrawn, Sponsor: Merck Sharp & Dohme Corp.
- dexamethasone / Generic mfg.
Enrollment change: Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block (clinicaltrials.gov) - Jun 6, 2012
P=N/A, N=24, Completed, Sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.
N=20 --> 14 N=50 --> 24
- || beclometasone/formoterol / Generic mfg., fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Enrollment change, Combination therapy, Real-world evidence, Real-world effectiveness, Real-world: Fos/Ser_switch: Real-world Effectiveness of Combination Therapies in Primary Care Asthma Management (clinicaltrials.gov) - Jun 6, 2012
P=N/A, N=137, Completed, Sponsor: Research in Real-Life Ltd
N=50 --> 24 N=1600 --> 137
- | Darzalex (daratumumab) / J&J
New P1/2 trial, Combination therapy: Daratumumab in Combination With Lenalidomide and Dexamethasone in Relapsed and Relapsed-refractory Multiple Myeloma (clinicaltrials.gov) - Jun 6, 2012
P1/2, N=50, Recruiting, Sponsor: Genmab
- dexamethasone / Generic mfg.
Trial completion: Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block (clinicaltrials.gov) - Jun 6, 2012
P=N/A, N=24, Completed, Sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.
N=1600 --> 137 Recruiting --> Completed
- ||| beclometasone/formoterol / Generic mfg., fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Trial completion, Combination therapy, Real-world evidence, Real-world effectiveness, Real-world: Fos/Ser_switch: Real-world Effectiveness of Combination Therapies in Primary Care Asthma Management (clinicaltrials.gov) - Jun 6, 2012
P=N/A, N=137, Completed, Sponsor: Research in Real-Life Ltd
Recruiting --> Completed Recruiting --> Completed
- | dexamethasone injection / Generic mfg.
New P4 trial: Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block (clinicaltrials.gov) - Jun 5, 2012
P4, N=80, Recruiting, Sponsor: Northwestern University
- | Ozurdex (dexamethasone intravitreal implant) / AbbVie
New P4 trial: Ozurdex for Diabetic Macular Edema Treated With Pars Plana vitrEctomy and Membrane RemovAl (OPERA Study) (clinicaltrials.gov) - Jun 5, 2012
P4, N=30, Recruiting, Sponsor: The Cleveland Clinic
- dexamethasone / Generic mfg., pomalidomide / Generic mfg.
Combination therapy: Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (clinicaltrials.gov) - Jun 5, 2012
P1, N=30, Recruiting, Sponsor: Celgene Corporation
Recruiting --> Completed Not yet recruiting --> Recruiting
- Neupogen (filgrastim) / Kyowa Kirin, Amgen, Mustargen (mechlorethamine) / Recordati
Enrollment closed: Chemotherapy With Low-Dose Radiation for Pediatric Hodgkin Lymphoma (clinicaltrials.gov) - Jun 5, 2012
P2, N=82, Active, not recruiting, Sponsor: St. Jude Children's Research Hospital
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- bortezomib / Generic mfg., dexamethasone / Generic mfg., dasatinib / Generic mfg.
Trial termination: Safety Study of Dasatinib With Bortezomib (Velcade (clinicaltrials.gov) - Jun 4, 2012
P1, N=16, Terminated, Sponsor: Bristol-Myers Squibb
Recruiting --> Active, not recruiting Completed --> Terminated
- bortezomib / Generic mfg., dexamethasone / Generic mfg., thalidomide / Generic mfg.
Trial termination: S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov) - Jun 4, 2012
P2, N=7, Terminated, Sponsor: Southwest Oncology Group
Completed --> Terminated Active, not recruiting --> Terminated; poor accrual
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial termination: S9922 Combination Chemo Plus Filgrastim With or Without Thalidomide in Refractory Multiple Myeloma (clinicaltrials.gov) - Jun 4, 2012
P3, N=19, Terminated, Sponsor: Southwest Oncology Group
Active, not recruiting --> Terminated; poor accrual Active, not recruiting --> Terminated; poor accrual
- bortezomib / Generic mfg., dexamethasone / Generic mfg., thalidomide / Generic mfg.
Enrollment change: S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov) - Jun 4, 2012
P2, N=7, Terminated, Sponsor: Southwest Oncology Group
Active, not recruiting --> Terminated; poor accrual N=90 --> 7
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
Enrollment change: S9922 Combination Chemo Plus Filgrastim With or Without Thalidomide in Refractory Multiple Myeloma (clinicaltrials.gov) - Jun 4, 2012
P3, N=19, Terminated, Sponsor: Southwest Oncology Group
N=90 --> 7 N=320 --> 19
- | dexamethasone injection / Generic mfg.
New P4 trial: Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty (clinicaltrials.gov) - Jun 4, 2012
P4, N=291, Completed, Sponsor: Tae Kyun Kim
- dexamethasone injection / Generic mfg.
Enrollment open, Surgery: The Effect of Dexamethasone on Cortisol Levels in Patients Undergoing Thyroid Surgery (clinicaltrials.gov) - Jun 4, 2012
P4, N=30, Recruiting, Sponsor: St. Paul's Hospital, Canada
N=320 --> 19 Not yet recruiting --> Recruiting
- Decadron (dexamethasone) / Merck (MSD)
Trial completion: S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis (clinicaltrials.gov) - Jun 4, 2012
P2, N=93, Completed, Sponsor: Southwest Oncology Group
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Synavive (prednisolone/dipyridamole) / Sun Pharma
New P2 trial: Long Term Safety Trial of z102 and Prednisone in Patients With Moderate to Severe Rheumatoid Arthritis (clinicaltrials.gov) - Jun 3, 2012
P2, N=18, Terminated, Sponsor: Zalicus
- ARC 100 / Cortice Biosci
Enrollment open, Metastases: TPI 287 in Breast Cancer Metastatic to the Brain (clinicaltrials.gov) - Jun 3, 2012
P2, N=69, Recruiting, Sponsor: M.D. Anderson Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Recruiting
- ||||| Onbrez (indacaterol) / Novartis
New P2 trial: Efficacy, Safety and Pharmacokinetics of Indacaterol Acetate in Patients With Persistent Asthma (clinicaltrials.gov) - May 30, 2012
P2, N=330, Completed, Sponsor: Novartis Pharmaceuticals
- hydrocortisone / Generic mfg.
Enrollment change: Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers (clinicaltrials.gov) - May 29, 2012
P1, N=50, Recruiting, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting --> Recruiting N=22 --> 50
- hydrocortisone / Generic mfg.
Enrollment open: Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers (clinicaltrials.gov) - May 29, 2012
P1, N=50, Recruiting, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
N=22 --> 50 Completed --> Recruiting
- || Emend intravenous (fosaprepitant) / Merck (MSD), Ono Pharma
New P3 trial: Examine the Efficacy and Safety of a Single Dose of Intravenous MK-0517 (EUDRACT) - May 24, 2012
P3, N=990, Ongoing, Sponsor: Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.`Merck Corporation, Inc.
- dexamethasone / Generic mfg.
New P1 trial, Surgery: A Safety and Efficacy Study of a Dexamethasone Drug Delivery System for Postoperative Inflammation and Pain After Cataract Surgery (clinicaltrials.gov) - May 23, 2012
P1, N=8, Terminated, Sponsor: Allergan
- | prednisolone / Generic mfg.
Trial initiation date: TryCort: Diagnostic Value of Oral Prednisolone Test for Rheumatoid Arthritis (clinicaltrials.gov) - May 22, 2012
P2/3, N=130, Enrolling by invitation, Sponsor: Rheumazentrum Ruhrgebiet
Completed --> Recruiting Initiation date: Oct 2011 --> Feb 2012
- | prednisolone / Generic mfg.
Enrollment open: TryCort: Diagnostic Value of Oral Prednisolone Test for Rheumatoid Arthritis (clinicaltrials.gov) - May 22, 2012
P2/3, N=130, Enrolling by invitation, Sponsor: Rheumazentrum Ruhrgebiet
Initiation date: Oct 2011 --> Feb 2012 Not yet recruiting --> Enrolling by invitation
- dexamethasone / Generic mfg.
Surgery: Effect of Dexamethasone and Methylprednisolone on Pain, Swelling and Trismus After Third Molar Surgery (clinicaltrials.gov) - May 21, 2012
P=N/A, N=18, Completed, Sponsor: Federal University of the Valleys of Jequitinhonha and Mucuri
- fludrocortisone / Generic mfg., hydrocortisone / Generic mfg.
Trial suspension: APROCCHS: Activated Protein C and Corticosteroids for Human Septic Shock (clinicaltrials.gov) - May 20, 2012
P3, N=1280, Suspended, Sponsor: University of Versailles
Not yet recruiting --> Enrolling by invitation Recruiting --> Suspended
- budesonide/formoterol / Generic mfg.
New P3 trial: Effect of Symbicort on Sleep Quality in Patients With Emphysema (clinicaltrials.gov) - May 17, 2012
P3, N=40, Active, not recruiting, Sponsor: Temple University
- dexamethasone / Generic mfg.
Clinical: Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and (clinicaltrials.gov) - May 16, 2012
P=N/A, N=23, Completed, Sponsor: University of Athens
- ||||| tabalumab (LY2127399) / Eli Lilly
New P2 trial, Combination therapy: A Study of Tabalumab (LY2127399) in Participants With Previously Treated Multiple Myeloma (MM) (clinicaltrials.gov) - May 16, 2012
P2, N=213, Active, not recruiting, Sponsor: Eli Lilly and Company
- Nanocort (liposomal prednisolone) / Galapagos, Enceladus
New P1/2 trial: Silencing Inflammatory Activity by Injecting Nanocort in Patients at Risk for Atherosclerotic Disease (clinicaltrials.gov) - May 15, 2012
P1/2, N=30, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- || dexamethasone / Generic mfg., lenalidomide / Generic mfg.
Enrollment closed: Non -Interventional Study-Palliative Therapy of Multiple Myeloma With a Combination of Lenalidomide and Dexamethasone (clinicaltrials.gov) - May 15, 2012
P=N/A, N=100, Active, not recruiting, Sponsor: iOMEDICO AG
Recruiting --> Suspended Recruiting --> Active, not recruiting
- fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Enrollment change: Elite Sport and Development of Asthma (clinicaltrials.gov) - May 14, 2012
P4, N=18, Completed, Sponsor: Bispebjerg Hospital
Recruiting --> Active, not recruiting N=40 --> 18
- fluticasone propionate/salmeterol xinafoate inhalation powder / Generic mfg.
Trial completion: Elite Sport and Development of Asthma (clinicaltrials.gov) - May 14, 2012
P4, N=18, Completed, Sponsor: Bispebjerg Hospital
N=40 --> 18 Recruiting --> Completed
- ||||| dexamethasone / Generic mfg., ropivacaine / Generic mfg.
Trial initiation date, Surgery: Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery (clinicaltrials.gov) - May 14, 2012
P3, N=120, Recruiting, Sponsor: Mayo Clinic
Recruiting --> Completed Initiation date: Nov 2011 --> May 2012
- dexamethasone / Generic mfg.
Enrollment open: The Effect of Prophylactic Antiemetic Dexamethasone on Plasma Cortisol Levels (clinicaltrials.gov) - May 14, 2012
P=N/A, N=63, Recruiting, Sponsor: William Li Pi Shan
Initiation date: Nov 2011 --> May 2012 Not yet recruiting --> Recruiting
- |||||| dexamethasone / Generic mfg., ropivacaine / Generic mfg.
Enrollment open, Surgery: Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery (clinicaltrials.gov) - May 14, 2012
P3, N=120, Recruiting, Sponsor: Mayo Clinic
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||| dexamethasone / Generic mfg., metamizole / Generic mfg.
Trial initiation date: Dextra: Efficacy and Safety of Injectable Association of Dexamethasone, Dipyrone and Hydrocobalamin in Lumbar Sciatic Pain (clinicaltrials.gov) - May 13, 2012
P3, N=280, Completed, Sponsor: Eurofarma Laboratorios S.A.
Not yet recruiting --> Recruiting Initiation date: Sep 2010 --> Feb 2011
- ||||||| dexamethasone / Generic mfg., metamizole / Generic mfg.
Trial completion: Dextra: Efficacy and Safety of Injectable Association of Dexamethasone, Dipyrone and Hydrocobalamin in Lumbar Sciatic Pain (clinicaltrials.gov) - May 13, 2012
P3, N=280, Completed, Sponsor: Eurofarma Laboratorios S.A.
Initiation date: Sep 2010 --> Feb 2011 Not yet recruiting --> Completed
- |||||||||| Emend intravenous (fosaprepitant) / Merck (MSD), Ono Pharma
New P3 trial: Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031) (clinicaltrials.gov) - May 7, 2012
P3, N=990, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
- |||||||||| Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Clinical: Combination Chemotherapy With or Without Rituximab in Treating Younger Patients With Stage III-IV Non-Hodgkin Lymphoma or B-Cell Acute Leukemia (clinicaltrials.gov) - May 7, 2012
P2/3, N=640, Recruiting, Sponsor: Children's Oncology Group