- |||||||||| Journal: Successful treatment with lithium carbonate for periodic psychosis of adolescence. (Pubmed Central) - Jun 19, 2025
Initial treatment with risperidone and aripiprazole was discontinued due to suspected neuroleptic malignant syndrome...Despite adequate treatment with quetiapine and olanzapine, episodes continued to recur...Six months after discharge, she had no recurrence of psychiatric symptoms. This case underscores the potential efficacy of lithium carbonate for periodic psychosis of adolescence and the importance of understanding this rare but distinctive psychiatric condition.
- |||||||||| digoxin / Generic mfg., bisoprolol / Generic mfg.
Journal: Enhanced efficacy of bisoprolol and digoxin combination in elderly patients with atrial fibrillation. (Pubmed Central) - Jun 19, 2025 In contrast to digoxin alone, combined application of bisoprolol and digoxin is more effective in treating elderly AF patients. The combined treatment can significantly improve LVEDD, LVESD, LVEF, and ventricular rate without increasing adverse reactions, making it a promising approach for clinical application.
- |||||||||| carvedilol / Generic mfg.
Journal: S- and R-Carvedilol Prevent Benzo(a)pyrene-Induced Lung Carcinogenesis. (Pubmed Central) - Jun 19, 2025 The results were confirmed by H&E-stained images of the mouse lungs. These findings support the hypothesis that carvedilol prevents B(a)P-induced lung inflammation and carcinogenesis independently of ?-blockade.
- |||||||||| propranolol / Generic mfg.
This Face is Not a PHACES (B3 - Ballroom Level) - Jun 19, 2025 - Abstract #CDA2025CDA_178; Empirical treatment with oral propranolol (2 mg/kg/day) was initiated while awaiting further diagnostic results...Conclusion This case underscores the diagnostic challenges posed by vascular anomalies, particularly in pediatric patients. Early identification and careful clinical and pathological assessment are crucial for appropriate management.
- |||||||||| midodrine hydrochloride / Generic mfg.
HD: Updated Review of Intradialytic Hypotension: Prediction and Management (Room 4(203)) - Jun 18, 2025 - Abstract #KSN2025KSN_381; Midodrine is a representative agent, acting on alpha-1 adrenergic receptors to increase blood pressure...Additionally, understanding the pharmacokinetics of different antihypertensive classes is essential. In general, calcium channel blockers (CCBs) are considered more suitable for IDH prevention compared to angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors (ACEIs).
- |||||||||| tamsulosin / Generic mfg., allopurinol / Generic mfg.
Kidney Stones: Pathogenesis and Treatment: Fluid and Electrolyte Challenges in Nephrology: from Bench to Bedside (Room 2(GBR 102)) - Jun 18, 2025 - Abstract #KSN2025KSN_132; In general, calcium channel blockers (CCBs) are considered more suitable for IDH prevention compared to angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors (ACEIs). Medical expulsive therapy, primarily using ?-blockers like tamsulosin, can aid the passage of small distal ureteral stones (Ferket et al., 2015)...Increased fluid intake (>2
- |||||||||| fentanyl citrate / Generic mfg., methamphetamine / Generic mfg.
Journal: Microarray-Based Nanoextraction Combined with Ambient Ionization Mass Spectrometry for Analysis of Drugs of Abuse in Wastewater. (Pubmed Central) - Jun 18, 2025 Under the optimized conditions (i.e., pH = 10, 23 nL of myristic acid as the extractant, and 20 min as the extraction time), the method was applied to a complex matrix (i.e., wastewater) as a proof-of-principle, giving limits of detection and preconcentration factors in the ranges of 0.194-0.871 ?g/L and 2.1-9.9, respectively. The chemically green(er) organic acid extractant, high preconcentration factors, and throughput are advantages of the proposed method.
- |||||||||| epinephrine / Generic mfg.
Preclinical, Journal: Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid. (Pubmed Central) - Jun 18, 2025 Additionally, epinephrine levels in the cerebral cortex decreased at 20 min (P < 0.05), while tyrosine levels in the brain stem and cerebellum decreased after 4 h (P < 0.05)...Exposure to ibotenic acid induces alterations in GABA/Glutamic-Acid, dopaminergic, serotonergic, and neurotransmitters associated with the cholinergic system in the brains of mice, with the most pronounced changes occurring in the brain stem region, exhibiting time-dependent and region-specific effects. This study offers new insights into the neurotoxic mechanisms of ibotenic acid.
- |||||||||| epinephrine / Generic mfg.
Journal: Evaluation of the awareness of pediatric residents of anaphylaxis diagnosis through clinical scenarios. (Pubmed Central) - Jun 18, 2025 In our country, the emergency treatment and follow-up of pediatric patients experiencing anaphylaxis are mostly carried out by pediatric specialists. Therefore, the education and training on the diagnosis and emergency management of anaphylaxis, a pediatric emergency, hold significant importance during the pediatric residency training period.
- |||||||||| lithium carbonate ER / Generic mfg.
Review, Journal: Pharmaco-psychiatry and gut microbiome: a systematic review of effects of psychotropic drugs for bipolar disorder. (Pubmed Central) - Jun 18, 2025 In bipolar patients treated with quetiapine, responders - those experiencing improved depressive symptom scores - displayed distinct gut microbiome profiles more closely resembling those of healthy individuals compared with non-responders...Nevertheless, this review highlights the potential of utilizing gut microbiota profiles to inform personalized treatment strategies, optimize therapeutic outcomes and minimize side effects in bipolar disorder. This study was registered with Open Science Framework (https://doi.org/10.17605/OSF.IO/3GUZR).
- |||||||||| nifedipine immediate release / Generic mfg., labetalol / Generic mfg.
Enrollment closed: P-PAT: Preeclampsia Postpartum Antihypertensive Treatment (clinicaltrials.gov) - Jun 18, 2025 P3, N=300, Active, not recruiting, This study was registered with Open Science Framework (https://doi.org/10.17605/OSF.IO/3GUZR). Recruiting --> Active, not recruiting
- |||||||||| bisoprolol / Generic mfg.
Journal: Antihypertensive treatment of a patient with normal blood pressure: case report and call for paying attention. (Pubmed Central) - Jun 18, 2025 Thereafter, she was instructed to keep continuing the life-style modification and given to beta-blocker (bisoprolol 5 mg) as an antihypertensive treatment...We have presented prosperous antihypertensive treatment of a female patient suffering from headache and dizziness with a numerically normal or nonelevated blood pressure. In the presence of symptoms and having not elevated or elevated blood pressure levels, patients' history on previous measure of blood pressure might facilitate our decision-making process.
- |||||||||| methamphetamine / Generic mfg.
Journal: Cognitive functioning of adolescents using Methamphetamine: The impact of inflammatory and oxidative processes. (Pubmed Central) - Jun 17, 2025 Our study showed that (I) IL-6 and TNF-a levels of Methamphetamine users were lower than the healthy group; (II) BDNF levels of Methamphetamine users were higher than the healthy group; (III) mean Neurocognitive Index in cognitive tests of Methamphetamine using adolescents was negatively correlated with duration of Methamphetamine use and BDNF levels. Our study suggests that Methamphetamine use may have a negative effect on cognitive functions.
- |||||||||| Journal: Co-occurring Anxiety in a Child With Autism and ADHD. (Pubmed Central) - Jun 17, 2025
Based on his developmental history, physical examination, review of school-based testing, and parent- and school-completed standardized questionnaires, he met Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for autism spectrum disorder and ADHD with combined presentation.When KM was between the ages of 8 and 10 years, he trialed several medications, including methylphenidate (which led to emotional lability), dextroamphetamine sulfate oral solution (which caused irritability), and clonidine (which led to destructive behavior)...He eventually was stabilized on extended-release dextroamphetamine-amphetamine at the age of 9 years, which both parents agreed was helpful for improving attention, despite the medication triggering a new self-injurious behavior of punching himself.At the age of 10 years, after 1 year of stability on dextroamphetamine-amphetamine extended-release capsule 10 mg daily, his parents chose not to refill the medication, to see whether it was still helpful for him...The DBP consulted a psychiatrist who advised a trial of escitalopram in conjunction with dextroamphetamine-amphetamine. Several weeks after starting escitalopram 5 mg per day, KM exhibited reduced anxious thoughts and decreased aggression, but ongoing symptoms of inattention.Considering KM's complex presentation, how do we approach neuropsychological assessment, behavioral and therapeutic support, and psychopharmacology?
- |||||||||| dobutamine / Generic mfg.
Journal: Comparison of Coronary Physiological Indices in Identifying Functionally Significant Myocardial Bridges in ANOCA. (Pubmed Central) - Jun 17, 2025 For Dobutamine RFR, the diagnostic accuracy was 96.9%, with a sensitivity of 95.8% and specificity of 100%. In patients with angina and nonobstructive coronary arteries and an MB confirmed by intravascular ultrasound, Dobutamine iFR and Dobutamine RFR may serve as alternatives to Dobutamine dFFR in identifying a functionally significant MB, with Dobutamine RFR having superior diagnostic accuracy.
- |||||||||| tamsulosin / Generic mfg., cefuroxime / Generic mfg., moxifloxacin intravenous / Generic mfg.
Journal: Cataracts: A Review. (Pubmed Central) - Jun 17, 2025 Intraocular antibiotics, such as moxifloxacin or cefuroxime, delivered intraoperatively have reduced the rates of sight-threatening postsurgical endophthalmitis from 0.07% to 0.02%...Cataracts are common among older adults and may cause visual disability and blindness without treatment. Cataract surgery reverses and prevents progressive vision loss, and advanced technology lens implants facilitate reduced dependence on eyeglasses.
- |||||||||| Review, Journal: Modulating Cognitive Function with Antihypertensive Medications: a (Pubmed Central) - Jun 17, 2025
Antihypertensive medications, such as losartan and propranolol, demonstrate potential in modulating memory, fear-related memory reconsolidation, and stress-induced memory modulation, highlighting their therapeutic implications for conditions like posttraumatic stress disorder (PTSD) and anxiety disorders. This review underscores the importance of fMRI studies in elucidating the neural correlates of HTN-related cognitive impairments and optimizing treatment approaches.
- |||||||||| methimazole / Generic mfg., propylthiouracil / Generic mfg., propranolol / Generic mfg.
Observational data, Retrospective data, Journal, Machine learning: Machine learning prediction of pancreatitis risk with antithyroid drugs: a nationwide retrospective observational study. (Pubmed Central) - Jun 17, 2025 Although the risk of experiencing AP was not increased by MMI use, propylthiouracil use increased and propranolol use decreased the risk of experiencing AP in patients with hyperthyroidism. Although drug-induced AP is relatively rare, a firm understanding of the drugs associated with the condition should alert the clinician to appropriately diagnose and treat patients.
- |||||||||| methamphetamine / Generic mfg.
Preclinical, Journal: Effects of methiopropamine on cognitive function and monoaminergic systems in mice. (Pubmed Central) - Jun 17, 2025 Methiopropamine (MPA), a novel psychoactive substance (NPS) similar to methamphetamine (METH), warrants investigation into its neurotoxic effects on cognitive function and behaviors due to limited existing research...This further suggests that MPA neurotoxicity is targeted at the dopaminergic transmission in the PFC. In conclusion, MPA consumption is associated with memory impairment, which is attributable to dopaminergic deficits and reduced p-ERK1/2 activities in the PFC.
- |||||||||| propranolol / Generic mfg.
Journal: Congenital Chylothorax and Congenital Pulmonary Airway Malformation: Case Report and Literature Review. (Pubmed Central) - Jun 17, 2025 Despite these interventions, the CCT persisted even with the subsequent administration of octreotide and propranolol...However, when CCT is associated with CPAM and fails to respond to conservative measures, thoracic duct ligation should be considered at the time of lung malformation resection. If these interventions remain ineffective, chemical pleurodesis is a viable therapeutic option.
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