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Sarcoma
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Tyrosine Kinase Inhibitors
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Phase 2
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Phase
N/A
1
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Trials
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erlotinib
/ Generic mfg.
Recentin
(cediranib) / AstraZeneca
Lenvima
(lenvatinib) / Eisai, Merck (MSD)
Sulanda
(surufatinib) / Hutchmed
dasatinib
/ Generic mfg.
Tyvyt
(sintilimab) / Eli Lilly
cixutumumab
(IMC A12) / Eli Lilly
Inlyta
(axitinib) / Pfizer
Vitrakvi
(larotrectinib) / Bayer
semaxanib
(SU5416) / Pfizer
Turalio
(pexidartinib) / Daiichi Sankyo
gefitinib
/ Generic mfg.
trebananib
(AMG 386) / Amgen
Caprelsa
(vandetanib) / Sanofi
Endostar
(recombinant human endostatin) / Simcere
Hiltonol
(poly-ICLC) / Oncovir
Zaltrap
(ziv-aflibercept IV) / Sanofi
Zelboraf
(vemurafenib) / Roche
Fruzaqla
(fruquintinib) / Takeda
dovitinib
(TKI258) / Novartis, Oncoheroes
figitumumab
(CP-751,871) / Novartis
ganetespib
(ADX-1612) / Aldeyra
Alecensa
(alectinib) / Roche
Avzivi
(bevacizumab-tnjn) / Bio-Thera Solutions, Cipla, BeiGene, Biomm, Mega Lifesciences, Sandoz
Kadcyla
(ado-trastuzumab emtansine) / Roche
Retevmo
(selpercatinib) / Eli Lilly
Rozlytrek
(entrectinib) / Roche
Vegzelma
(bevacizumab-adcd) / Celltrion
Xalkori
(crizotinib) / Pfizer
motesanib
(AMG 706) / Takeda
rilotumumab
(AMG 102) / Amgen
vatalanib
(PTK787) / Novartis, Bayer
Balversa
(erdafitinib) / J&J
Cyramza
(ramucirumab) / Eli Lilly
Ensacove
(ensartinib) / Betta Pharma
Fotivda
(tivozanib) / Kyowa Kirin, Jazz, LG Chem
Gilotrif
(afatinib) / Boehringer Ingelheim
Iclusig
(ponatinib) / Takeda, Otsuka
Pexa-Vec
(pexastimogene devacirepvec) / SillaJen, Transgene
Tepezza
(teprotumumab-trbw) / Roche, Amgen
chiauranib
(CS 2164) / Chipscreen
linsitinib
(ASP7487) / Sling Therap
nintedanib
/ Generic mfg.
patritumab
(U3-1287) / Amgen, Daiichi Sankyo
robatumumab
(SCH 717454) / Merck (MSD)
sEphB4-HSA
/ VasGene, National Cancer Institute
saracatinib
(AZD0530) / AstraZeneca
tandutinib
(MLN518) / Takeda
tivantinib
(ARQ 197) / Daiichi Sankyo, Kyowa Kirin, Merck (MSD)
zanidatamab
(ZW25) / Jazz
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