DDR enhancer 
Welcome,         Profile    Billing    Logout  
  Companies   Products    Products    Diseases    Trials    News 
5 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
PLX038 / ProLynx
NCT05465941: PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Recruiting
2
43
US
Biopsy, Bx, BIOPSY_TYPE, Pegylated SN-38 Conjugate PLX038, Pegylated SN-38 PLX038, PLX 038, PLX-038, PLX038, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, computerized axial tomography, Computerized axial tomography (procedure), Computerized Tomography, CT, CT SCAN, tomography, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection
Mayo Clinic, National Cancer Institute (NCI)
Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Ovarian Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
05/27
12/31
TOPOLOGY, NCT06162351: A Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer

Recruiting
2
44
Europe
PLX038
Institut Curie, ProLynx LLC
Breast, Cancer
08/25
03/26
NCT04209595: PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers

Active, not recruiting
1/2
10
US
PLX038, PEGylated SN38, Rucaparib, Rubraca, Ondansetron, Zofran
National Cancer Institute (NCI)
Small Cell Lung Cancer, Extra-Pulmonary Small Cell Carcinomas
08/21
12/24
NCT06161519: PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Recruiting
1/2
120
US
PLX038
National Cancer Institute (NCI)
Glioma, Medulloblastoma, Ependymoma
11/28
11/33
POP-ART, NCT06337630: A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors

Not yet recruiting
1
92
Europe
PLX038 + Tuvusertib
Institut Curie, ProLynx LLC, Merck Sharp & Dohme LLC
Solid Tumor
06/25
02/29
GLIX1 / Hemispherian
No trials found

Download Options