Cannabinoid receptor 1 agon 
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131 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Epidiolex (cannabidiol) / Jazz
NCT04899050: Epidiolex in Typical Absence Seizures

Completed
4
14
US
Cannabidiol (Epidiolex)
University of South Florida, Jazz Pharmaceuticals
Study the Efficacy of Epidiolex for Typical Absence Seizures
05/23
05/23
NCT04749628: Cannabidiol for Bilateral Total Knee Arthroplasty

Completed
4
37
US
cannabidiol, Epidiolex, Ora-sweet SF
Hospital for Special Surgery, New York
Pain, Postoperative, Opioid Use, Knee Osteoarthritis
10/24
01/25
CAN-SAD, NCT05649059: Investigating the Effects of Cannabidiol on Social Anxiety Disorder

Not yet recruiting
4
50
US
Cannabidiol, Epidiolex, Placebo
Massachusetts Institute of Technology, Massachusetts General Hospital
Phobia, Social
05/25
09/25
NCT05324449: Epidiolex® for Anxiety in Pediatric Epilepsy

Recruiting
4
20
US
Cannabidiol 100 MG/ML, Epidiolex
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Anxiety, Epilepsy
04/25
04/26
EpiCom, NCT05864846: A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

Recruiting
4
75
Europe, Canada, US
Cannabidiol Oral Solution [Epidiolex], Epidiolex
Jazz Pharmaceuticals
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
01/26
01/26
NCT05044819: Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Active, not recruiting
4
154
US
Cannabidiol, Epidiolex
Jazz Pharmaceuticals, Jazz Pharmaceuticals Research UK Limited
Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
08/27
03/28
ACTRN12621001659897: A pilot randomised controlled trial testing the efficacy of cannabidiol for anxiety in Tourette Syndrome

Not yet recruiting
3
40
 
Children's Health Queensland Hospital and Health Service, Children's Health Queensland Hospital and Health Service
Tourette Syndrome, Anxiety
 
 
ACTRN12623000526673: A Randomised Controlled Trial of Cannabidiol (CBD) for the treatment of Cannabis Use Disorder (CUD)

Recruiting
3
250
 
University of Sydney, National Health and Medical Research Council
Cannabis use disorder, Drug addiction
 
 
NCT04611438: Research on Cognitive Effect of Cannabidiol on Dravet Syndrome and Lennox-Gastaut SyndromeGastaut Syndrome

Recruiting
3
107
RoW
Cannabidiol
Yonsei University
Dravet Syndrome, Lennox Gastaut Syndrome
03/21
06/21
NCT05016349: Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.

Not yet recruiting
3
160
NA
All trans-retinoic acid, Vesanoid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone, Cannabidiol, Epidiolex, 9 cis retinoic acid, Tamoxifen, Standard therapy
Mahmoud Ramadan mohamed Elkazzaz, Ministry of Health, Saudi Arabia
Breast Cancer Female
10/21
12/21
2021-003094-61: A safety and efficacy study of cannabidiol oral solution (GWP42003-P) in children and adolescents with epilepsy between 1 and 18 years of age, inclusive Studio sulla sicurezza e sull’efficacia della soluzione orale di cannabidiolo (GWP42003-P) in bambini e adolescenti affetti da epilessia di età compresa tra 1 e 18 anni compiuti.

Not yet recruiting
3
240
Europe
Cannabidiol (CBD), [GWP42003-P], Oral solution, Soluzione orale di CBD, conosciuta e approvata in EU come Epidyolex 100mg/ml soluzione orale
GW RESEARCH LTD., GW Research Ltd
Epilepsy with myoclonic-atonic seizures epilessia con crisi miocloniche-atoniche, Epilepsy with seizures epilessia con convulsioni, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT05288283: Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

Terminated
3
3
Europe, US
GWP42003-P, EPIDIOLEX, Cannabidiol, Cannabidiol oral solution (CBD-OS), Placebo
Jazz Pharmaceuticals
Seizures Associated With EMAS
09/23
09/23
NCT04485104 / 2020-002132-67: Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Terminated
3
3
Europe, US
GWP42003-P, Cannabidiol, Epidiolex, Epidyolex
Jazz Pharmaceuticals
Seizure in Participants With Tuberous Sclerosis Complex, Seizure in Participants With Dravet Syndrome, Seizure in Participants With Lennox-Gastaut Syndrome
01/25
01/25
NCT06333041: Study of Cannabidiol in Sanfilippo Syndrome

Not yet recruiting
2/3
35
US
Epidiolex, Cannabidiol; CBD, Placebo
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Sanfilippo Syndrome, Mucopolysaccharidosis III
06/26
01/27
2019-001633-14: A pilot study to assess the efficacy and safety of CBD oral solution in addition to standard treatment for pediatric subjects with Developmental and Epileptic Encephalopathy Studio pilota per valutare una soluzione orale a base di cannabidiolo (CBD) in aggiunta al trattamento standard di bambini affetti da Encefalopatia Evolutiva ed Epilettica (DEE)

Not yet recruiting
2
20
Europe
Epidiolex, [Epidiolex], Oral solution, Epidiolex
IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA, GW Pharmaceuticals
Developmental and Epileptic Encephalopathy (DEE) Encefalopatia Evolutiva ed Epilettica (DEE), Developmental and Epileptic Encephalopathy (DEE) Encefalopatia Evolutiva ed Epilettica (DEE), Diseases [C] - Nervous System Diseases [C10]
 
 
2021-001959-13: Adjunctive cannabidiol therapy in patients with CDKL5 deficiency disorder. Interventional drug study on efficacy and safety with focus on seizure effects Terapia con cannabidiolo in add-on nei pazienti con sindrome CDKL5. Studio interventistico con farmaco su efficacia e sicurezza con un focus sugli effetti delle crisi epilettiche.

Not yet recruiting
2
15
Europe
Epidyolex, [Epidyolex], Oral solution, Epidyolex
FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE, GW Researched Limited Cambridge
patients with CDKL5 pazienti con sindrome CDKL5, patients with CDKL5 pazienti con sindrome CDKL5, Diseases [C] - Nervous System Diseases [C10]
 
 
2019-003369-16: An irregular trial in which the identity of those receiving the intervention in twin groups is concealed from both the administrators and subject until the test is completed. The trial is to check the safety and efficacy of GWP42003-P versus Placebo as a joining therapy in Participants with Schizophrenia Experiencing Inadequate Response to Ongoing Antipsychotic Treatment. Un ensayo irregular en el que la identidad de quienes reciben la intervención en grupos gemelos se oculta tanto a los administradores como al sujeto hasta que se completa la prueba.El estudio es para investigar la seguridad y la eficacia de GWP42003-P frente a placebo como tratamiento complementario en participantes con esquizofrenia que experimenten respuesta inadecuada al tratamiento con antipsicóticos en curso.

Not yet recruiting
2
366
Europe
Cannabidiol (CBD), GWP42003-P, Oral solution, CBD-Oral Solution, is known as Epidyolex, and is the approved name in the EU
GW Research Ltd., GW Research Ltd
Schizophrenia is neurodevelopmental syndrome, results from gradual alterations in brain connectivity. Can persist for years before psychosis emerges. Individuals have a 2 to 3 fold increased risk of death from a range of comorbid somatic conditions and suicide, the former attributable to unhealthy lifestyle, predisposition, and antipsychotic medication. Individuals typically smoke, can be overweight or obese, suffer from hypertension, dyslipidemias, metabolic syndrome, and diabetes. Esquizofrenia es un síndrome del neurodesarrollo resultado de alteraciones graduales en la conectividad cerebral.Puede persistir durante años antes de que surja la psicosis.El riesgo de muerte es de 2 a 3 veces mayor debido a una variedad de afecciones somáticas comórbidas y suicidio,el primero atribuible a un estilo de vida poco saludable,predisposición y medicamentos antipsicóticos. Las personas suelen fumar,tener sobrepeso u obesidad, hipertensión,dislipidemias,síndrome metabólico ydiabetes, schizophrenia is a severe long-term mental health condition. It causes a range of different psychological symptoms. La esquizofrenia es una afección grave de salud mental a largo plazo. Causa una variedad de síntomas psicológicos diferentes, Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
NCT04482244: RCT of CBD for Anxiety in Advanced Breast Cancer

Active, not recruiting
2
50
US
Cannabidiol, Epidiolex, CBD, Placebo
Dana-Farber Cancer Institute, Hans and Mavis Lopater Foundation
Advanced Breast Cancer, Anxiety, CBD
09/24
09/25
NCT04517799: Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism

Active, not recruiting
2
42
US
Epidiolex, cannabidiol, placebo oral solution
University of California, San Diego, Wholistic Research and Education Foundation, Center for Medicinal Cannabis Research
Autism, Autism Spectrum Disorder
06/25
12/25
NCT04978428: Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Recruiting
2
15
US
Cannabidiol, Epidiolex
University of Chicago
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
11/25
11/25
GWND19189, NCT04745026 / 2020-002819-21: Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder

Completed
2
103
Europe, Canada, US, RoW
GWP42003-P, Epidiolex®, cannabidiol, CBD-OS, Placebo
Jazz Pharmaceuticals
Autism Spectrum Disorder
12/23
12/23
NCT04754399: Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias

Completed
2
40
US
Cannabidiol (CBD), Epidiolex
University of Michigan Rogel Cancer Center, American Society of Clinical Oncology
Arthralgia, Breast Cancer
10/23
10/23
EBCBD, NCT05651607: Evaluation of the Efficacy of CANNABIDIOL on the Pruritus in Children With Hereditary Epidermolysis Bullosa

Completed
2
10
Europe
Cannabidiol, Epidyolex
Assistance Publique - Hôpitaux de Paris, HELEBOR, Fondation Apicil, Lions Club International Foundation
Hereditary Epidermolysis Bullosa
11/23
11/23
NCT06213233: MIVetsCan: Cannabidiol (CBD)-Care Trial

Recruiting
2
468
US
Placebo, Cannabidiol, Epidiolex
Kevin Boehnke, Michigan, State of, Licensing and Regulatory Affairs
Pain, Chronic
12/26
12/26
CORK, NCT06234631: Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Recruiting
2
380
US
Epidiolex oral solution, Cannabidiol, Placebo
Chad Brummett, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Knee Replacement Surgery, Osteoarthritis, Knee
01/29
01/29
NCI-2022-02479, NCT05388058: Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy

Completed
2
30
US
Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Placebo Administration, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
Mayo Clinic, National Cancer Institute (NCI)
Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm
07/23
07/23
CHAPPII, NCT05942911: Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis

Suspended
2
20
RoW
IHL-675A, Cannabidiol, CBD, Epidiolex, Epydiolex, Hydroxychloroquine, HCQ, Plaquenil, Placebo
Incannex Healthcare Ltd
Rheumatoid Arthritis
10/24
10/25
NCT04105231: Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use

Recruiting
2
64
Europe
Cannabidiol, Epidiolex, Risperidone, Risperidon
Lone Baandrup, Danish Center for Sleep Medicine, Copenhagen University Hospital, Denmark, Glostrup University Hospital, Copenhagen, University of Copenhagen
Dual Diagnosis
06/25
06/25
NCT05823753: Cannabidiol to Reduce Anxiety Reactivity

Completed
2
63
US
Cannabidiol, Epidiolex, Placebo
University of California, San Diego
Social Anxiety, Social Anxiety Disorder
08/24
08/24
NCT06840899: CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury

Not yet recruiting
2
20
US
CBD, Epidiolex
University of Wisconsin, Madison
Supra-sacral Spinal Cord Injury, Spinal Cord Injury, Urinary Incontinence
01/27
01/27
NCT04992624: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

Recruiting
2
200
US
Placebo, Cannabidiol (CBD), Epidiolex, Tetrahydrocannabinol (Marinol® or generic equivalent (e.g., dronabinol), Dronabinol
Steven E Harte, PhD, National Center for Complementary and Integrative Health (NCCIH), National Institute on Drug Abuse (NIDA)
Osteoarthritis, Knee, Osteoarthritis of the Knee
10/26
10/26
NCT06538389: High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer

Recruiting
2
36
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, BRC-001, Cannabidiol, CBD, CBD Oil, Placebo Administration, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI), Biopharmaceutical Research Company
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Breast Adenocarcinoma, Breast Ductal Carcinoma In Situ, Estrogen Receptor-Positive Breast Carcinoma, Progesterone Receptor-Positive Breast Carcinoma
08/26
08/26
NCT04620512: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

Not yet recruiting
2
200
US
Placebo, THC 10 mg/day, dronabinol, Marinol, CBD 150 mg/day, Epidiolex®, CBD 150 mg/day plus THC 10 mg/day
Richard Harris, National Institute on Drug Abuse (NIDA), National Center for Complementary and Integrative Health (NCCIH)
Osteoarthritis, Knee
10/25
10/25
NCT06731894: Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Not yet recruiting
2
120
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Dronabinol, (-)-.DELTA.9-Tetrahydrocannabinol, Abbott 40566, Delta(9)-Tetrahydrocannibinol, Delta-9-Tetrahydrocannabinol, Delta-9-THC, Delta9-THC, Marinol, SP 104, SP-104, SYNDROS, Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol, Tetrahydrocannabinol, THC, Placebo Administration, Survey Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/26
10/26
NCT05269628: Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype

Recruiting
2
166
US
Cannabidiol (CBD), Epidiolex® 100 mg/mL solution, Tetrahydrocannabinol (THC), Marinol®, dronabinol capsules, Placebo CBD, Placebo THC
Tiffany J. Braley, MD, MS, National Center for Complementary and Integrative Health (NCCIH)
Multiple Sclerosis, Sleep, Pain
06/27
06/27
NCT05066308: Cannabidiol for Reduction of Brain Neuroinflammation

Recruiting
2
80
US
CBD, Epidiolex, Placebo
Massachusetts General Hospital
Back Pain, Depressive Symptoms
09/26
12/26
NCT03014440: Study of Cannabidiol for Drug-Resistant Epilepsies

No Longer Available
1/2
NA
Cannabidiol, CBD, Epidiolex
Eric Marsh, MD, University of Pittsburgh, Geisinger Clinic
Drug Resistant Epilepsy
 
 
NCT04642404: CBD for Dental Pain

Completed
1/2
64
US
Epidiolex 100 mg/mL Oral Solution, Cannabidiol (CBD), Placebo
The University of Texas Health Science Center at San Antonio
Odontalgia, Toothache
03/23
03/23
NCT05132699: Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder

Completed
1/2
21
US
Cannabidiol (CBD) oral solution, Epidiolex, Placebo, Placebo oral solution, Massed Prolonged Exposure (mPE), Behavioral Therapy
The University of Texas Health Science Center at San Antonio, National Center for Advancing Translational Sciences (NCATS)
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
06/23
06/23
CBD, NCT06381791: for Pain Following Orthopedic Shoulder Surgery

Recruiting
1/2
80
US
Epidiolex, Cannabidiol Oral Solution, Placebo oral solution, Placebo
The Methodist Hospital Research Institute
Shoulder Osteoarthritis, Rotator Cuff Injuries
12/26
12/27
ACTRN12622000289718p: A Phase I Clinical Trial of IHL-675A to Assess Safety and Pharmacokinetics in Healthy Volunteers

Not yet recruiting
1
36
 
Incannex Healthcare Ltd, Incannex Healthcare Ltd
Inflammation
 
 
ACTRN12622000427774: A Phase I Clinical Trial comparing Pharmacokinetics of EMD-RX5 Cannabidiol (CBD) capsules to Epidyolex CBD oil in Healthy Volunteers.

Completed
1
12
 
Emyria Ltd, Emyria Ltd
psychological distress
 
 
2016-000936-17: A randomized trial to evaluate the safety, tolerability, and pharmacokinetics of GWP42003-P in conjunction with therapeutic hypothermia in neonates with moderate or severe birth asphyxia

Not yet recruiting
1
32
Europe
Cannabidiol (CBD), GWP42003-P, Solution for infusion
GW Research Ltd, GW Research Ltd
Neonatal Hypoxic-Ischemic Encephalopathy, Brain injury caused by a lack of oxygen-rich blood in a newborn's brain, Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
 
 
ACTRN12622000289718: A Phase I Clinical Trial of IHL-675A to Assess Safety and Pharmacokinetics in Healthy Volunteers

Completed
1
36
 
Incannex Healthcare Ltd, Incannex Healthcare Ltd
Inflammation
 
 
NCT05023070: Investigation of the Pharmacokinetic Profile of CBD

Completed
1
24
US
Cannabidiol, Nantheia ATL5, Epidiolex
Icahn School of Medicine at Mount Sinai
Healthy
02/23
02/23
ACTRN12623000730606: A Phase 1, 2-Part, Open-Label, Pilot Trial to Assess the Relative Bioavailability of 3 Formulations of Cannabidiol (CBD) under FASTED (Part A) and FED (Part B) conditions in Healthy Adult Male Subjects.

Completed
1
15
 
Sapient Therapeutics (Australia) PTY Ltd, Sapient Therapeutics (Australia) PTY Ltd
Neurological
 
 
NCT04721691: Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).

Recruiting
1
34
US
Epidiolex 100 mg/mL Oral Solution, Placebo
Northwell Health, Jazz Pharmaceuticals
Electrical Status Epilepticus of Slow-Wave Sleep
01/25
04/25
NCT06192589: Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions

Recruiting
1
240
US
Cannabidiol, Epidiolex, Placebo, Citalopram, Celexa, Morphine
Food and Drug Administration (FDA), Spaulding Clinical Research LLC
Cannabidiol, Drug Induced Liver Injury, Drug Interaction
09/24
09/24
NCT04231643: Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers

Terminated
1
19
US
Dronabinol, Epidiolex, Placebos
University of California, San Diego, National Institute on Drug Abuse (NIDA)
Bipolar Disorder
11/23
11/23
NCT04777643: Sex Differences in Neural Response to Cannabidiol

Completed
1
19
US
Cannabidiol, Placebo
Yale University
CBD, Neural Responses
04/23
04/23
NCT04878627: Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa

Active, not recruiting
1
40
US
Cannabidiol, Epidiolex, Placebo
University of California, San Diego
Anorexia Nervosa
11/25
11/25
NCT06578455: A Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions

Completed
1
32
Canada
Cannabidiol (CBD) Powder, CBD-NE, Cannabidiol 100 MG/ML [Epidiolex], Epidyolex
DSM Nutritional Products, Inc., Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
CBD Pharmacokinetics, Healthy Participants
11/24
12/24
NCT05269706: Investigation of the Pharmacokinetic Profile of CBD

Completed
1
60
US
Cannabidiol 200mg, BSPG CBD, Epidiolex, Cannabidiol 400mg, Placebo
Yasmin Hurd
Opioid Use Disorder
02/23
02/23
NCT05672342: Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Withdrawn
1
120
US
Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Delta-8-Tetrahydrocannabinol, .DELTA.8-TETRAHYDROCANNABINOL, delta-8-THC, Placebo Administration, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/25
10/25
NCT05490511: Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus

Recruiting
1
72
US
Tacrolimus single dose, Period 1, Epidiolex single dose, Period 2, Epidiolex steady-state and tacrolimus single dose, Period 3
Indiana University, The National Center for Complementary and Integrative Health
CBD, Transplant Complication, Kidney Disease, Chronic
10/28
10/28
ACTRN12624000888561: Cannabidiol on beyond-Seizure outcomes in children and adults with Developmental and Epileptic Encephalopathy

Not yet recruiting
N/A
20
 
Hunter New England Local Health District, Jazz Pharmaceuticals
Epilepsy
 
 
ACTRN12623000855628: Effect of cannabidiol on sleep in developmental and epileptic encephalopathies

Not yet recruiting
N/A
26
 
Alfred Health, Jazz Pharmaceuticals
Epilepsy
 
 
NCT02556008: Cannabidiol for Pediatric Epilepsy (Compassionate Use)

No Longer Available
N/A
US
cannabidiol (CBD), Epidiolex
University of California, Los Angeles
Refractory Childhood Epilepsy
 
 
CBD, NCT02397863: Epidiolex and Drug Resistant Epilepsy in Children

Available
N/A
US
Cannabidiol (Epidiolex), Epidiolex
Augusta University, State of Georgia
Epilepsy
12/19
01/20
OPERA, NCT05772429: Long-Term Follow-Up of a Cohort of Participants Prescribed Epidyolex in France in a Real-life Setting

Completed
N/A
158
Europe
Epidiolex, Cannabidiol, Epidyolex
Jazz Pharmaceuticals
Seizures
07/24
07/24
EpiTALY, NCT05485831: Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY

Recruiting
N/A
100
Europe
Epidiolex 100 mg/mL Oral Solution
Jazz Pharmaceuticals, Advice Pharma Group srl
Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
01/26
01/26
NCT06113237: Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

Recruiting
N/A
50
US
Epidiolex, Epidyolex, Cannabidiol
Jazz Pharmaceuticals
Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
08/33
08/33
Cesamet (nabilone) / Bausch Health, Viatris
NABI, NCT05885685: Investigating the Effects of Nabilone on Endocannabinoid Metabolism

Recruiting
4
30
Canada
Nabilone Oral Capsule, TEVA-nabilone
Centre for Addiction and Mental Health
Healthy
10/26
10/26
2009-011862-27: Überprufung der wirksamkeit und Sicherheit einer Add-on Therapie mit dem synthetischen Cannabinomimetikum Nabilone bei Patienten mit Tumorschmerz

Ongoing
3
40
Europe
Nabilone 0,5 mg,
ZISOP Zentrum für interdisziplinäre Schmerztherapie Landeskrankenhaus Klagenfurt
Pain related to cancer (solid tumors)
 
 
2017-004253-16: Investigation of the effect of Nabilon in patients suffering from Parkinson´s Disease with non-Motor symptoms (e.g.sleeping dirsorders, cognitive dysfunction, hallucinations, autonomic dysfunction,...)

Ongoing
3
48
Europe
Nabilone, Capsule, hard
Medizinische Universität Innsbruck, Universitätsklinik für Neurologie, AOP Orphan Pharmaceuticals AG
Subject with non-Motor symptoms of Parkinson´s disease, Parkinson´s disease, Diseases [C] - Nervous System Diseases [C10]
 
 
DISCO-POT, NCT05180968: DIalysis Symptom COntrol-Pruritus Outcome Trial

Completed
3
14
Canada
Nabilone 0.5 MG Oral Capsule, TEVA-Nabilone, Placebo Nabilone, TEVA-Nabilone Placebo
University of Manitoba, Population Health Research Institute
End Stage Renal Disease, Pruritus
08/23
08/23
NAB-IT, NCT04516057: Nabilone for Agitation Blinded Intervention Trial

Recruiting
3
112
Canada
Nabilone, Cesamet, Placebo
Sunnybrook Health Sciences Centre, Alzheimer's Drug Discovery Foundation, Weston Brain Institute
Alzheimer Disease, Agitation
10/25
10/25
CATNP, NCT04057456: Cannabinoids and an Anti-inflammatory Diet for the Treatment of Neuropathic Pain After Spinal Cord Injury

Recruiting
3
140
Canada
Placebo diet, Anti-inflammatory diet, Nabilone Capsules, Placebo capsules
Eldon Loh, MD, Ontario Neurotrauma Foundation
Spinal Cord Injuries, Neuropathic Pain
06/26
12/26
2015-004227-31: Clinical pilot study to review the impact of perioperative administration of the synthetic cannabinoid nabilone in the context of spinal fusion surgery on the coping with surgery and the pain perception of patients with severely reduced quality of life Klinische Pilotstudie zur Überprüfung des Einflusses einer perioperativen Einnahme des synthetischen Cannabinoids Nabilon im Rahmen stabilisierender Wirbelsäulenoperationen auf die Operationsbewältigung und das Schmerzempfinden von Patienten mit stark reduzierter Lebensqualität

Ongoing
2
36
Europe
Capsule, Canemes 1 mg Kapseln
OA Dr. Philipp Becker c/o Abteilung für Wirbelsäulenchirurgie, Orthopädisches Spital Speising GmbH, Orthopädisches Spital Speising GmbH, AOP Orphan Pharmaceuticals AG
Spine disease Wirbelsäulenerkrankung, Spine disease Wirbelsäulenerkrankung, Diseases [C] - Musculoskeletal Diseases [C05]
 
 
2017-000192-86: Investigation of the effect of Nabilon in patients suffering from Parkinson´s Disease with non-motor symptoms (e.g.sleeping disorders,cognitive dysfunction, hallucinations, autonomic dysfunction including urinary incontinence, constipation,...)

Ongoing
2
48
Europe
Nabilone, Capsule
Medizinische Universität Innsbruck, Universitätsklinik für Neurologie, AOP Orphan Pharmaceuticals AG
Subjects with non-motor symptoms of Parkinson´s disease, Parkinson´s disease, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT04801641: A Pilot Trial of Nabilone for the Treatment of Obesity

Terminated
2
24
Canada
Placebo, Nabilone
Centre for Addiction and Mental Health
Obesity
08/23
08/23
NCT05494437: Effect of PP-01 on Cannabis Withdrawal Syndrome

Completed
2
234
US
PP-01 High Dose, PP-01 Low Dose, Placebo, Nabilone, Gabapentin
PleoPharma, Inc.
Cannabis Withdrawal
08/23
08/23
AgiNab, NCT05742698: Nabilone for Agitation in Frontotemporal Dementia

Recruiting
2
45
Canada
Nabilone, Nabilone Oral Capsule, TEVA Nabilone, Placebo
Simon Ducharme, MD, Alzheimer's Drug Discovery Foundation
Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant, Primary Progressive Aphasia, bvFTD, PPA, FTD
04/26
05/26
NCT04880278: Multimodal Assessment of Cannabinoid Target Engagement in Adults With Obsessive-Compulsive Disorder

Withdrawn
1/2
60
US
Nabilone, Cesamet (brand name), Placebo
New York State Psychiatric Institute, National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
05/24
05/24
N-AND, NCT05273320: Clinical Trial of Nabilone for Aggression in Adults with Intellectual and Developmental Disabilities

Recruiting
1
30
Canada
Nabilone, 02392925 Teva-Nabilone 0.25 mg Capsule; 02384892 Teva-Nabilone 1 mg Capsule
Hsiang-Yuan Lin
Intellectual Disability, Developmental Disability, Aggression, Behavior Problem
12/25
12/25
NCT03422861: Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients

Not yet recruiting
N/A
80
Canada
Nabilone, Cesamet, Placebos
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Inflammatory Bowel Diseases
09/24
12/24
ACTRN12618001292268: Perceptual Effects of Caffeine and Nabilone (PECAN)

Recruiting
N/A
66
 
University of Western Australia, University of Western Australia
Psychosis, Schizophrenia
 
 
dronabinol oral / Generic mfg.
2005-000817-37: A Study On The Efficacy Of Delta-9-Tetrahydrocannabinol (Dronabinol) In Renal Itch

Ongoing
4
24
Europe
Dronabinol, Marinol®, Marinol®
Cardiff University
Itch associated with chronic renal failure
 
 
NCT04734080: Dronabinol in Total Knee Arthroplasty (TKA)

Completed
4
114
US
Dronabinol 5mg Cap, marinol, Placebo oral tablet, placebo
Hospital for Special Surgery, New York
Total Knee Arthroplasty, Opioid Use
10/23
04/24
DOPE, NCT05820685: Dronabinol On the Pain Experience

Terminated
4
482
US
Standard of care, Dronabinol
The University of Texas Health Science Center, Houston, The Eastern Association for the Surgery of Trauma
Trauma Injury
04/24
04/24
PrECEPT, NCT04374773: Effects of Pregnancy-associated Hormones on THC Metabolism in Women

Active, not recruiting
4
12
US
Dronabinol, THC, tetrahydrocannabinol
University of Washington, National Institute on Drug Abuse (NIDA)
Pregnancy Related, Cannabis Use
03/25
08/25
2005-002728-33: Cannabinoid Use in Progressive Inflammatory brain Disease

Ongoing
3
492
Europe
Dronabinol,
Plymouth Hospitals NHS Trust
Progressive multiple sclerosis
 
 
NCT05335252: Dronabinol After Arthroscopic Surgery

Recruiting
3
30
US
Dronabinol, Marinol, Placebo
Northwestern University
Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
12/24
06/25
dronabinol, NCT04298528: A RCT Comparing Dronabinol to a Placebo for Post-operative Pain in Total Joint Arthroplasty

Recruiting
3
460
US
Dronabinol, Marinol, Placebo, Lactose
Colorado Joint Replacement
Osteoarthritis, Knee
02/24
02/25
2022-004238-20: BONG: Breathlessness and alternatives to Opioid treatment in Non-malign Groups of severe lung disease Lindring af svær åndenød med Dronabinol hos patienter med svær Kronisk Obstruktiv Lungesygdom (KOL)

Not yet recruiting
3
30
Europe
Dronabinol kapsel 2,5 mg, Capsule, soft
Vejle Hospital, Vejle Hospital
COPD, Chronic obstructive pulmonary disease, Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09]
 
 
BONG, NCT06473701: Reducing Breathlessness With Dronabinol in COPD Patients

Recruiting
3
30
Europe
Dronabinol 2.5mg Capsule, Delta9-tetrahydrocannabinol, Placebo
Vejle Hospital, Region of Southern Denmark, Odense Patient Data Explorative Network, University of Southern Denmark, University of Aarhus
COPD, Breathlessness, Cannabis
04/26
07/26
POINT, NCT06175273: Pediatric Oncology Nutrition Intervention Trial

Recruiting
2/3
45
US
Oral Nutrition Supplement, Tube Feed, Cyproheptadine, Olanzapine, Standard of Care
Corey Hawes, National Center for Advancing Translational Sciences (NCATS)
Pediatric Cancer, Nutrition Related Cancer, Nutrition Aspect of Cancer, Muscle Loss, Malnutrition, Child
03/25
03/25
NAVE-Sci-001, NCT05239390: SCI-110 for Alzheimer Disease and Agitation

Recruiting
2a
20
RoW
SCI -110, Dronabinol and PEA
The Israeli Medical Center for Alzheimer's
Alzheimer Disease
06/23
06/23
ACTRN12619000491167: Tetrahydrocannabinol for cancer-related anorexia

Recruiting
2
250
 
Palliative Care Clinical Studies Collaborative, NSW Health
Cancer-related anorexia
 
 
2006-004482-33: Investigating the acute effects of THC on functional brain systems

Ongoing
2
21
Europe
Dronabinol,
University Medical Center Utrecht
This research project will be performed with healthy volunteers in order to determine whether THC modulates activity in functional brain systems.
 
 
2017-004226-15: Can-ArtEffect and safety of using Canabis derivatives for the treatment of pain in patients with inflammatory Arthritis, such as reumatoid arthritis and ankylosing spondylitis, the latter being a type of arthritis that causes a long term inflammation of the joints of the spine. A randomized, double blinded, placebo controlled trial, i.e. in this drug trial, a control group is given a placebo while another group is given the Cannabis derivative being studied. Can-ArtEffekt og sikkerhed ved anvendelse af Canabis-derivater til behandling af smerte hos patienter med inflammatorisk arthritis, såsom rheumatoid arthritis og ankyloserende spondylitis (sidstnævnte er en type arthritis, der forårsager langvarig betændelse i rygsøjlen og bækkenet).En randomiseret, dobbeltblindet, placebokontrolleret forsøg, dvs. i denne lægemiddelforsøg, gives en kontrolgruppe en placebo, mens en anden gruppe får substansen, der undersøges, dvs. Cannabis derivatet.

Ongoing
2
180
Europe
Cannabidiol tablet 10 mg, Dronabinol capsule 2.5. mg, Tablet, Capsule
King Christian 10th Hospital for Rheumatology, The Danish Rheumatism Association, The Region of Southern Denmark
Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS), RA and AS are autoimmune diseases. In RA the immune system attacks the membranes lining the joints, typically initially in small joints. AS affects the joints of the spine and the pelvic girdle., Diseases [C] - Musculoskeletal Diseases [C05]
 
 
2017-004823-66: Early-life stress, the endocannabinoid system, and fear memory extinction

Ongoing
2
48
Europe
Namisol, Hydrocortison CF, ECP002A, RVG 50730, Tablet, Hydrocortison CF
Radboudumc, Radboudumc
healthy volunteers gezonde vrijwilligers, intended indication: posttraumatic stress disorder (PTSD) beoogde indicatie: posttraumatic stress disorder (PTSD), Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
2018-000014-38: A Phase IIa Study to Determine the Safety, Tolerability and Efficacy of a daily oral dose of THX-110 in Adult Patients with Tourette Syndrome (TS)

Not yet recruiting
2
60
Europe
THX-110 [Dronabinol], THX-110 [PEA (Palmitoylethanolamide)], Capsule, soft, Tablet, Dronabinol Capsules, USP
Therapix Biosciences Ltd., Therapix Biosciences Ltd.
Tourette Syndrome, Neuropsychiatric disorder characterized by multiple motor or vocal tics., Diseases [C] - Nervous System Diseases [C10]
 
 
2021-000305-24: Evaluating the effects of a novel drug on THC effects

Ongoing
2
100
Europe
ANEB001, NAMISOL®, ANEB001, Capsule, soft, Tablet
Anebulo pharmaceuticals, Inc., Anebulo pharmaceuticals, Inc.
THC intoxication, THC overdose, Not possible to specify
 
 
NCT04596826 / 2019-003089-42: The Effect of Dronabinol on Ocular Hemodynamics in Patients With Primary Open Angle Glaucoma

Recruiting
2
100
Europe
Dronabinol 5 MG, Dronabinol 10 MG, Placebo
Medical University of Vienna
Retinal Blood Flow
10/23
10/23
THC-AD, NCT02792257: Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease

Completed
2
75
US
Dronabinol (Marinol®), Placebo
Johns Hopkins University, Mclean Hospital, Miami Jewish Health, National Institute on Aging (NIA), Tufts Medical Center
Alzheimer's Disease
05/24
05/24
DARP, NCT06454669: Dronabinol as an Adjunct for Reducing Pain

Recruiting
2
75
US
Dronabinol, Marinol, delta-9-tetrahydrocannabinol, Placebo
Christopher D. Verrico
Low Back Pain, Chronic Pain, Back Injuries
12/26
12/27
NCT06446479: Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Recruiting
2
28
US
Dronabinol Pill, Placebo
University of Colorado, Denver, National Institute on Alcohol Abuse and Alcoholism (NIAAA), Colorado State University
Cannabis Use Disorder
06/26
06/26
NCT06834997: Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's Hospital

Not yet recruiting
2
75
US
Dronabinol Capsules, Marinol, delta-9-tetrahydrocannabinol, Placebo
Baylor College of Medicine
Endometriosis, Endometriosis Related Pain, Endometriosis, Pain
12/27
05/28
NCT05477875: Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control

Completed
2
35
US
oral cannabinoid, dronabinol, oral codeine/acetaminophen
University of Florida, Consortium for Medical Marijuana Clinical Outcomes Research
Photorefractive Keratectomy, Myopia, Hyperopia
01/25
01/25
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Epidiolex (cannabidiol) / Jazz
NCT04899050: Epidiolex in Typical Absence Seizures

Completed
4
14
US
Cannabidiol (Epidiolex)
University of South Florida, Jazz Pharmaceuticals
Study the Efficacy of Epidiolex for Typical Absence Seizures
05/23
05/23
NCT04749628: Cannabidiol for Bilateral Total Knee Arthroplasty

Completed
4
37
US
cannabidiol, Epidiolex, Ora-sweet SF
Hospital for Special Surgery, New York
Pain, Postoperative, Opioid Use, Knee Osteoarthritis
10/24
01/25
CAN-SAD, NCT05649059: Investigating the Effects of Cannabidiol on Social Anxiety Disorder

Not yet recruiting
4
50
US
Cannabidiol, Epidiolex, Placebo
Massachusetts Institute of Technology, Massachusetts General Hospital
Phobia, Social
05/25
09/25
NCT05324449: Epidiolex® for Anxiety in Pediatric Epilepsy

Recruiting
4
20
US
Cannabidiol 100 MG/ML, Epidiolex
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Anxiety, Epilepsy
04/25
04/26
EpiCom, NCT05864846: A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

Recruiting
4
75
Europe, Canada, US
Cannabidiol Oral Solution [Epidiolex], Epidiolex
Jazz Pharmaceuticals
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
01/26
01/26
NCT05044819: Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

Active, not recruiting
4
154
US
Cannabidiol, Epidiolex
Jazz Pharmaceuticals, Jazz Pharmaceuticals Research UK Limited
Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
08/27
03/28
ACTRN12621001659897: A pilot randomised controlled trial testing the efficacy of cannabidiol for anxiety in Tourette Syndrome

Not yet recruiting
3
40
 
Children's Health Queensland Hospital and Health Service, Children's Health Queensland Hospital and Health Service
Tourette Syndrome, Anxiety
 
 
ACTRN12623000526673: A Randomised Controlled Trial of Cannabidiol (CBD) for the treatment of Cannabis Use Disorder (CUD)

Recruiting
3
250
 
University of Sydney, National Health and Medical Research Council
Cannabis use disorder, Drug addiction
 
 
NCT04611438: Research on Cognitive Effect of Cannabidiol on Dravet Syndrome and Lennox-Gastaut SyndromeGastaut Syndrome

Recruiting
3
107
RoW
Cannabidiol
Yonsei University
Dravet Syndrome, Lennox Gastaut Syndrome
03/21
06/21
NCT05016349: Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.

Not yet recruiting
3
160
NA
All trans-retinoic acid, Vesanoid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone, Cannabidiol, Epidiolex, 9 cis retinoic acid, Tamoxifen, Standard therapy
Mahmoud Ramadan mohamed Elkazzaz, Ministry of Health, Saudi Arabia
Breast Cancer Female
10/21
12/21
2021-003094-61: A safety and efficacy study of cannabidiol oral solution (GWP42003-P) in children and adolescents with epilepsy between 1 and 18 years of age, inclusive Studio sulla sicurezza e sull’efficacia della soluzione orale di cannabidiolo (GWP42003-P) in bambini e adolescenti affetti da epilessia di età compresa tra 1 e 18 anni compiuti.

Not yet recruiting
3
240
Europe
Cannabidiol (CBD), [GWP42003-P], Oral solution, Soluzione orale di CBD, conosciuta e approvata in EU come Epidyolex 100mg/ml soluzione orale
GW RESEARCH LTD., GW Research Ltd
Epilepsy with myoclonic-atonic seizures epilessia con crisi miocloniche-atoniche, Epilepsy with seizures epilessia con convulsioni, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT05288283: Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

Terminated
3
3
Europe, US
GWP42003-P, EPIDIOLEX, Cannabidiol, Cannabidiol oral solution (CBD-OS), Placebo
Jazz Pharmaceuticals
Seizures Associated With EMAS
09/23
09/23
NCT04485104 / 2020-002132-67: Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Terminated
3
3
Europe, US
GWP42003-P, Cannabidiol, Epidiolex, Epidyolex
Jazz Pharmaceuticals
Seizure in Participants With Tuberous Sclerosis Complex, Seizure in Participants With Dravet Syndrome, Seizure in Participants With Lennox-Gastaut Syndrome
01/25
01/25
NCT06333041: Study of Cannabidiol in Sanfilippo Syndrome

Not yet recruiting
2/3
35
US
Epidiolex, Cannabidiol; CBD, Placebo
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Sanfilippo Syndrome, Mucopolysaccharidosis III
06/26
01/27
2019-001633-14: A pilot study to assess the efficacy and safety of CBD oral solution in addition to standard treatment for pediatric subjects with Developmental and Epileptic Encephalopathy Studio pilota per valutare una soluzione orale a base di cannabidiolo (CBD) in aggiunta al trattamento standard di bambini affetti da Encefalopatia Evolutiva ed Epilettica (DEE)

Not yet recruiting
2
20
Europe
Epidiolex, [Epidiolex], Oral solution, Epidiolex
IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA, GW Pharmaceuticals
Developmental and Epileptic Encephalopathy (DEE) Encefalopatia Evolutiva ed Epilettica (DEE), Developmental and Epileptic Encephalopathy (DEE) Encefalopatia Evolutiva ed Epilettica (DEE), Diseases [C] - Nervous System Diseases [C10]
 
 
2021-001959-13: Adjunctive cannabidiol therapy in patients with CDKL5 deficiency disorder. Interventional drug study on efficacy and safety with focus on seizure effects Terapia con cannabidiolo in add-on nei pazienti con sindrome CDKL5. Studio interventistico con farmaco su efficacia e sicurezza con un focus sugli effetti delle crisi epilettiche.

Not yet recruiting
2
15
Europe
Epidyolex, [Epidyolex], Oral solution, Epidyolex
FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE, GW Researched Limited Cambridge
patients with CDKL5 pazienti con sindrome CDKL5, patients with CDKL5 pazienti con sindrome CDKL5, Diseases [C] - Nervous System Diseases [C10]
 
 
2019-003369-16: An irregular trial in which the identity of those receiving the intervention in twin groups is concealed from both the administrators and subject until the test is completed. The trial is to check the safety and efficacy of GWP42003-P versus Placebo as a joining therapy in Participants with Schizophrenia Experiencing Inadequate Response to Ongoing Antipsychotic Treatment. Un ensayo irregular en el que la identidad de quienes reciben la intervención en grupos gemelos se oculta tanto a los administradores como al sujeto hasta que se completa la prueba.El estudio es para investigar la seguridad y la eficacia de GWP42003-P frente a placebo como tratamiento complementario en participantes con esquizofrenia que experimenten respuesta inadecuada al tratamiento con antipsicóticos en curso.

Not yet recruiting
2
366
Europe
Cannabidiol (CBD), GWP42003-P, Oral solution, CBD-Oral Solution, is known as Epidyolex, and is the approved name in the EU
GW Research Ltd., GW Research Ltd
Schizophrenia is neurodevelopmental syndrome, results from gradual alterations in brain connectivity. Can persist for years before psychosis emerges. Individuals have a 2 to 3 fold increased risk of death from a range of comorbid somatic conditions and suicide, the former attributable to unhealthy lifestyle, predisposition, and antipsychotic medication. Individuals typically smoke, can be overweight or obese, suffer from hypertension, dyslipidemias, metabolic syndrome, and diabetes. Esquizofrenia es un síndrome del neurodesarrollo resultado de alteraciones graduales en la conectividad cerebral.Puede persistir durante años antes de que surja la psicosis.El riesgo de muerte es de 2 a 3 veces mayor debido a una variedad de afecciones somáticas comórbidas y suicidio,el primero atribuible a un estilo de vida poco saludable,predisposición y medicamentos antipsicóticos. Las personas suelen fumar,tener sobrepeso u obesidad, hipertensión,dislipidemias,síndrome metabólico ydiabetes, schizophrenia is a severe long-term mental health condition. It causes a range of different psychological symptoms. La esquizofrenia es una afección grave de salud mental a largo plazo. Causa una variedad de síntomas psicológicos diferentes, Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
NCT04482244: RCT of CBD for Anxiety in Advanced Breast Cancer

Active, not recruiting
2
50
US
Cannabidiol, Epidiolex, CBD, Placebo
Dana-Farber Cancer Institute, Hans and Mavis Lopater Foundation
Advanced Breast Cancer, Anxiety, CBD
09/24
09/25
NCT04517799: Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism

Active, not recruiting
2
42
US
Epidiolex, cannabidiol, placebo oral solution
University of California, San Diego, Wholistic Research and Education Foundation, Center for Medicinal Cannabis Research
Autism, Autism Spectrum Disorder
06/25
12/25
NCT04978428: Epidiolex in Obsessive Compulsive Disorder and Related Disorders

Recruiting
2
15
US
Cannabidiol, Epidiolex
University of Chicago
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
11/25
11/25
GWND19189, NCT04745026 / 2020-002819-21: Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder

Completed
2
103
Europe, Canada, US, RoW
GWP42003-P, Epidiolex®, cannabidiol, CBD-OS, Placebo
Jazz Pharmaceuticals
Autism Spectrum Disorder
12/23
12/23
NCT04754399: Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias

Completed
2
40
US
Cannabidiol (CBD), Epidiolex
University of Michigan Rogel Cancer Center, American Society of Clinical Oncology
Arthralgia, Breast Cancer
10/23
10/23
EBCBD, NCT05651607: Evaluation of the Efficacy of CANNABIDIOL on the Pruritus in Children With Hereditary Epidermolysis Bullosa

Completed
2
10
Europe
Cannabidiol, Epidyolex
Assistance Publique - Hôpitaux de Paris, HELEBOR, Fondation Apicil, Lions Club International Foundation
Hereditary Epidermolysis Bullosa
11/23
11/23
NCT06213233: MIVetsCan: Cannabidiol (CBD)-Care Trial

Recruiting
2
468
US
Placebo, Cannabidiol, Epidiolex
Kevin Boehnke, Michigan, State of, Licensing and Regulatory Affairs
Pain, Chronic
12/26
12/26
CORK, NCT06234631: Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Recruiting
2
380
US
Epidiolex oral solution, Cannabidiol, Placebo
Chad Brummett, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Knee Replacement Surgery, Osteoarthritis, Knee
01/29
01/29
NCI-2022-02479, NCT05388058: Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy

Completed
2
30
US
Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Placebo Administration, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
Mayo Clinic, National Cancer Institute (NCI)
Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm
07/23
07/23
CHAPPII, NCT05942911: Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis

Suspended
2
20
RoW
IHL-675A, Cannabidiol, CBD, Epidiolex, Epydiolex, Hydroxychloroquine, HCQ, Plaquenil, Placebo
Incannex Healthcare Ltd
Rheumatoid Arthritis
10/24
10/25
NCT04105231: Cannabidiol for Treatment of Non-affective Psychosis and Cannabis Use

Recruiting
2
64
Europe
Cannabidiol, Epidiolex, Risperidone, Risperidon
Lone Baandrup, Danish Center for Sleep Medicine, Copenhagen University Hospital, Denmark, Glostrup University Hospital, Copenhagen, University of Copenhagen
Dual Diagnosis
06/25
06/25
NCT05823753: Cannabidiol to Reduce Anxiety Reactivity

Completed
2
63
US
Cannabidiol, Epidiolex, Placebo
University of California, San Diego
Social Anxiety, Social Anxiety Disorder
08/24
08/24
NCT06840899: CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury

Not yet recruiting
2
20
US
CBD, Epidiolex
University of Wisconsin, Madison
Supra-sacral Spinal Cord Injury, Spinal Cord Injury, Urinary Incontinence
01/27
01/27
NCT04992624: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

Recruiting
2
200
US
Placebo, Cannabidiol (CBD), Epidiolex, Tetrahydrocannabinol (Marinol® or generic equivalent (e.g., dronabinol), Dronabinol
Steven E Harte, PhD, National Center for Complementary and Integrative Health (NCCIH), National Institute on Drug Abuse (NIDA)
Osteoarthritis, Knee, Osteoarthritis of the Knee
10/26
10/26
NCT06538389: High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer

Recruiting
2
36
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, BRC-001, Cannabidiol, CBD, CBD Oil, Placebo Administration, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI), Biopharmaceutical Research Company
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Breast Adenocarcinoma, Breast Ductal Carcinoma In Situ, Estrogen Receptor-Positive Breast Carcinoma, Progesterone Receptor-Positive Breast Carcinoma
08/26
08/26
NCT04620512: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

Not yet recruiting
2
200
US
Placebo, THC 10 mg/day, dronabinol, Marinol, CBD 150 mg/day, Epidiolex®, CBD 150 mg/day plus THC 10 mg/day
Richard Harris, National Institute on Drug Abuse (NIDA), National Center for Complementary and Integrative Health (NCCIH)
Osteoarthritis, Knee
10/25
10/25
NCT06731894: Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Not yet recruiting
2
120
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Dronabinol, (-)-.DELTA.9-Tetrahydrocannabinol, Abbott 40566, Delta(9)-Tetrahydrocannibinol, Delta-9-Tetrahydrocannabinol, Delta-9-THC, Delta9-THC, Marinol, SP 104, SP-104, SYNDROS, Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol, Tetrahydrocannabinol, THC, Placebo Administration, Survey Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/26
10/26
NCT05269628: Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype

Recruiting
2
166
US
Cannabidiol (CBD), Epidiolex® 100 mg/mL solution, Tetrahydrocannabinol (THC), Marinol®, dronabinol capsules, Placebo CBD, Placebo THC
Tiffany J. Braley, MD, MS, National Center for Complementary and Integrative Health (NCCIH)
Multiple Sclerosis, Sleep, Pain
06/27
06/27
NCT05066308: Cannabidiol for Reduction of Brain Neuroinflammation

Recruiting
2
80
US
CBD, Epidiolex, Placebo
Massachusetts General Hospital
Back Pain, Depressive Symptoms
09/26
12/26
NCT03014440: Study of Cannabidiol for Drug-Resistant Epilepsies

No Longer Available
1/2
NA
Cannabidiol, CBD, Epidiolex
Eric Marsh, MD, University of Pittsburgh, Geisinger Clinic
Drug Resistant Epilepsy
 
 
NCT04642404: CBD for Dental Pain

Completed
1/2
64
US
Epidiolex 100 mg/mL Oral Solution, Cannabidiol (CBD), Placebo
The University of Texas Health Science Center at San Antonio
Odontalgia, Toothache
03/23
03/23
NCT05132699: Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder

Completed
1/2
21
US
Cannabidiol (CBD) oral solution, Epidiolex, Placebo, Placebo oral solution, Massed Prolonged Exposure (mPE), Behavioral Therapy
The University of Texas Health Science Center at San Antonio, National Center for Advancing Translational Sciences (NCATS)
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
06/23
06/23
CBD, NCT06381791: for Pain Following Orthopedic Shoulder Surgery

Recruiting
1/2
80
US
Epidiolex, Cannabidiol Oral Solution, Placebo oral solution, Placebo
The Methodist Hospital Research Institute
Shoulder Osteoarthritis, Rotator Cuff Injuries
12/26
12/27
ACTRN12622000289718p: A Phase I Clinical Trial of IHL-675A to Assess Safety and Pharmacokinetics in Healthy Volunteers

Not yet recruiting
1
36
 
Incannex Healthcare Ltd, Incannex Healthcare Ltd
Inflammation
 
 
ACTRN12622000427774: A Phase I Clinical Trial comparing Pharmacokinetics of EMD-RX5 Cannabidiol (CBD) capsules to Epidyolex CBD oil in Healthy Volunteers.

Completed
1
12
 
Emyria Ltd, Emyria Ltd
psychological distress
 
 
2016-000936-17: A randomized trial to evaluate the safety, tolerability, and pharmacokinetics of GWP42003-P in conjunction with therapeutic hypothermia in neonates with moderate or severe birth asphyxia

Not yet recruiting
1
32
Europe
Cannabidiol (CBD), GWP42003-P, Solution for infusion
GW Research Ltd, GW Research Ltd
Neonatal Hypoxic-Ischemic Encephalopathy, Brain injury caused by a lack of oxygen-rich blood in a newborn's brain, Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
 
 
ACTRN12622000289718: A Phase I Clinical Trial of IHL-675A to Assess Safety and Pharmacokinetics in Healthy Volunteers

Completed
1
36
 
Incannex Healthcare Ltd, Incannex Healthcare Ltd
Inflammation
 
 
NCT05023070: Investigation of the Pharmacokinetic Profile of CBD

Completed
1
24
US
Cannabidiol, Nantheia ATL5, Epidiolex
Icahn School of Medicine at Mount Sinai
Healthy
02/23
02/23
ACTRN12623000730606: A Phase 1, 2-Part, Open-Label, Pilot Trial to Assess the Relative Bioavailability of 3 Formulations of Cannabidiol (CBD) under FASTED (Part A) and FED (Part B) conditions in Healthy Adult Male Subjects.

Completed
1
15
 
Sapient Therapeutics (Australia) PTY Ltd, Sapient Therapeutics (Australia) PTY Ltd
Neurological
 
 
NCT04721691: Efficacy of Epidiolex in Patients With Electrical Status Epilepticus of Sleep (ESES).

Recruiting
1
34
US
Epidiolex 100 mg/mL Oral Solution, Placebo
Northwell Health, Jazz Pharmaceuticals
Electrical Status Epilepticus of Slow-Wave Sleep
01/25
04/25
NCT06192589: Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions

Recruiting
1
240
US
Cannabidiol, Epidiolex, Placebo, Citalopram, Celexa, Morphine
Food and Drug Administration (FDA), Spaulding Clinical Research LLC
Cannabidiol, Drug Induced Liver Injury, Drug Interaction
09/24
09/24
NCT04231643: Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers

Terminated
1
19
US
Dronabinol, Epidiolex, Placebos
University of California, San Diego, National Institute on Drug Abuse (NIDA)
Bipolar Disorder
11/23
11/23
NCT04777643: Sex Differences in Neural Response to Cannabidiol

Completed
1
19
US
Cannabidiol, Placebo
Yale University
CBD, Neural Responses
04/23
04/23
NCT04878627: Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa

Active, not recruiting
1
40
US
Cannabidiol, Epidiolex, Placebo
University of California, San Diego
Anorexia Nervosa
11/25
11/25
NCT06578455: A Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions

Completed
1
32
Canada
Cannabidiol (CBD) Powder, CBD-NE, Cannabidiol 100 MG/ML [Epidiolex], Epidyolex
DSM Nutritional Products, Inc., Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
CBD Pharmacokinetics, Healthy Participants
11/24
12/24
NCT05269706: Investigation of the Pharmacokinetic Profile of CBD

Completed
1
60
US
Cannabidiol 200mg, BSPG CBD, Epidiolex, Cannabidiol 400mg, Placebo
Yasmin Hurd
Opioid Use Disorder
02/23
02/23
NCT05672342: Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Withdrawn
1
120
US
Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Delta-8-Tetrahydrocannabinol, .DELTA.8-TETRAHYDROCANNABINOL, delta-8-THC, Placebo Administration, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/25
10/25
NCT05490511: Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus

Recruiting
1
72
US
Tacrolimus single dose, Period 1, Epidiolex single dose, Period 2, Epidiolex steady-state and tacrolimus single dose, Period 3
Indiana University, The National Center for Complementary and Integrative Health
CBD, Transplant Complication, Kidney Disease, Chronic
10/28
10/28
ACTRN12624000888561: Cannabidiol on beyond-Seizure outcomes in children and adults with Developmental and Epileptic Encephalopathy

Not yet recruiting
N/A
20
 
Hunter New England Local Health District, Jazz Pharmaceuticals
Epilepsy
 
 
ACTRN12623000855628: Effect of cannabidiol on sleep in developmental and epileptic encephalopathies

Not yet recruiting
N/A
26
 
Alfred Health, Jazz Pharmaceuticals
Epilepsy
 
 
NCT02556008: Cannabidiol for Pediatric Epilepsy (Compassionate Use)

No Longer Available
N/A
US
cannabidiol (CBD), Epidiolex
University of California, Los Angeles
Refractory Childhood Epilepsy
 
 
CBD, NCT02397863: Epidiolex and Drug Resistant Epilepsy in Children

Available
N/A
US
Cannabidiol (Epidiolex), Epidiolex
Augusta University, State of Georgia
Epilepsy
12/19
01/20
OPERA, NCT05772429: Long-Term Follow-Up of a Cohort of Participants Prescribed Epidyolex in France in a Real-life Setting

Completed
N/A
158
Europe
Epidiolex, Cannabidiol, Epidyolex
Jazz Pharmaceuticals
Seizures
07/24
07/24
EpiTALY, NCT05485831: Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY

Recruiting
N/A
100
Europe
Epidiolex 100 mg/mL Oral Solution
Jazz Pharmaceuticals, Advice Pharma Group srl
Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
01/26
01/26
NCT06113237: Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

Recruiting
N/A
50
US
Epidiolex, Epidyolex, Cannabidiol
Jazz Pharmaceuticals
Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
08/33
08/33
Cesamet (nabilone) / Bausch Health, Viatris
NABI, NCT05885685: Investigating the Effects of Nabilone on Endocannabinoid Metabolism

Recruiting
4
30
Canada
Nabilone Oral Capsule, TEVA-nabilone
Centre for Addiction and Mental Health
Healthy
10/26
10/26
2009-011862-27: Überprufung der wirksamkeit und Sicherheit einer Add-on Therapie mit dem synthetischen Cannabinomimetikum Nabilone bei Patienten mit Tumorschmerz

Ongoing
3
40
Europe
Nabilone 0,5 mg,
ZISOP Zentrum für interdisziplinäre Schmerztherapie Landeskrankenhaus Klagenfurt
Pain related to cancer (solid tumors)
 
 
2017-004253-16: Investigation of the effect of Nabilon in patients suffering from Parkinson´s Disease with non-Motor symptoms (e.g.sleeping dirsorders, cognitive dysfunction, hallucinations, autonomic dysfunction,...)

Ongoing
3
48
Europe
Nabilone, Capsule, hard
Medizinische Universität Innsbruck, Universitätsklinik für Neurologie, AOP Orphan Pharmaceuticals AG
Subject with non-Motor symptoms of Parkinson´s disease, Parkinson´s disease, Diseases [C] - Nervous System Diseases [C10]
 
 
DISCO-POT, NCT05180968: DIalysis Symptom COntrol-Pruritus Outcome Trial

Completed
3
14
Canada
Nabilone 0.5 MG Oral Capsule, TEVA-Nabilone, Placebo Nabilone, TEVA-Nabilone Placebo
University of Manitoba, Population Health Research Institute
End Stage Renal Disease, Pruritus
08/23
08/23
NAB-IT, NCT04516057: Nabilone for Agitation Blinded Intervention Trial

Recruiting
3
112
Canada
Nabilone, Cesamet, Placebo
Sunnybrook Health Sciences Centre, Alzheimer's Drug Discovery Foundation, Weston Brain Institute
Alzheimer Disease, Agitation
10/25
10/25
CATNP, NCT04057456: Cannabinoids and an Anti-inflammatory Diet for the Treatment of Neuropathic Pain After Spinal Cord Injury

Recruiting
3
140
Canada
Placebo diet, Anti-inflammatory diet, Nabilone Capsules, Placebo capsules
Eldon Loh, MD, Ontario Neurotrauma Foundation
Spinal Cord Injuries, Neuropathic Pain
06/26
12/26
2015-004227-31: Clinical pilot study to review the impact of perioperative administration of the synthetic cannabinoid nabilone in the context of spinal fusion surgery on the coping with surgery and the pain perception of patients with severely reduced quality of life Klinische Pilotstudie zur Überprüfung des Einflusses einer perioperativen Einnahme des synthetischen Cannabinoids Nabilon im Rahmen stabilisierender Wirbelsäulenoperationen auf die Operationsbewältigung und das Schmerzempfinden von Patienten mit stark reduzierter Lebensqualität

Ongoing
2
36
Europe
Capsule, Canemes 1 mg Kapseln
OA Dr. Philipp Becker c/o Abteilung für Wirbelsäulenchirurgie, Orthopädisches Spital Speising GmbH, Orthopädisches Spital Speising GmbH, AOP Orphan Pharmaceuticals AG
Spine disease Wirbelsäulenerkrankung, Spine disease Wirbelsäulenerkrankung, Diseases [C] - Musculoskeletal Diseases [C05]
 
 
2017-000192-86: Investigation of the effect of Nabilon in patients suffering from Parkinson´s Disease with non-motor symptoms (e.g.sleeping disorders,cognitive dysfunction, hallucinations, autonomic dysfunction including urinary incontinence, constipation,...)

Ongoing
2
48
Europe
Nabilone, Capsule
Medizinische Universität Innsbruck, Universitätsklinik für Neurologie, AOP Orphan Pharmaceuticals AG
Subjects with non-motor symptoms of Parkinson´s disease, Parkinson´s disease, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT04801641: A Pilot Trial of Nabilone for the Treatment of Obesity

Terminated
2
24
Canada
Placebo, Nabilone
Centre for Addiction and Mental Health
Obesity
08/23
08/23
NCT05494437: Effect of PP-01 on Cannabis Withdrawal Syndrome

Completed
2
234
US
PP-01 High Dose, PP-01 Low Dose, Placebo, Nabilone, Gabapentin
PleoPharma, Inc.
Cannabis Withdrawal
08/23
08/23
AgiNab, NCT05742698: Nabilone for Agitation in Frontotemporal Dementia

Recruiting
2
45
Canada
Nabilone, Nabilone Oral Capsule, TEVA Nabilone, Placebo
Simon Ducharme, MD, Alzheimer's Drug Discovery Foundation
Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant, Primary Progressive Aphasia, bvFTD, PPA, FTD
04/26
05/26
NCT04880278: Multimodal Assessment of Cannabinoid Target Engagement in Adults With Obsessive-Compulsive Disorder

Withdrawn
1/2
60
US
Nabilone, Cesamet (brand name), Placebo
New York State Psychiatric Institute, National Institute of Mental Health (NIMH)
Obsessive-Compulsive Disorder
05/24
05/24
N-AND, NCT05273320: Clinical Trial of Nabilone for Aggression in Adults with Intellectual and Developmental Disabilities

Recruiting
1
30
Canada
Nabilone, 02392925 Teva-Nabilone 0.25 mg Capsule; 02384892 Teva-Nabilone 1 mg Capsule
Hsiang-Yuan Lin
Intellectual Disability, Developmental Disability, Aggression, Behavior Problem
12/25
12/25
NCT03422861: Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients

Not yet recruiting
N/A
80
Canada
Nabilone, Cesamet, Placebos
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Inflammatory Bowel Diseases
09/24
12/24
ACTRN12618001292268: Perceptual Effects of Caffeine and Nabilone (PECAN)

Recruiting
N/A
66
 
University of Western Australia, University of Western Australia
Psychosis, Schizophrenia
 
 
dronabinol oral / Generic mfg.
2005-000817-37: A Study On The Efficacy Of Delta-9-Tetrahydrocannabinol (Dronabinol) In Renal Itch

Ongoing
4
24
Europe
Dronabinol, Marinol®, Marinol®
Cardiff University
Itch associated with chronic renal failure
 
 
NCT04734080: Dronabinol in Total Knee Arthroplasty (TKA)

Completed
4
114
US
Dronabinol 5mg Cap, marinol, Placebo oral tablet, placebo
Hospital for Special Surgery, New York
Total Knee Arthroplasty, Opioid Use
10/23
04/24
DOPE, NCT05820685: Dronabinol On the Pain Experience

Terminated
4
482
US
Standard of care, Dronabinol
The University of Texas Health Science Center, Houston, The Eastern Association for the Surgery of Trauma
Trauma Injury
04/24
04/24
PrECEPT, NCT04374773: Effects of Pregnancy-associated Hormones on THC Metabolism in Women

Active, not recruiting
4
12
US
Dronabinol, THC, tetrahydrocannabinol
University of Washington, National Institute on Drug Abuse (NIDA)
Pregnancy Related, Cannabis Use
03/25
08/25
2005-002728-33: Cannabinoid Use in Progressive Inflammatory brain Disease

Ongoing
3
492
Europe
Dronabinol,
Plymouth Hospitals NHS Trust
Progressive multiple sclerosis
 
 
NCT05335252: Dronabinol After Arthroscopic Surgery

Recruiting
3
30
US
Dronabinol, Marinol, Placebo
Northwestern University
Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
12/24
06/25
dronabinol, NCT04298528: A RCT Comparing Dronabinol to a Placebo for Post-operative Pain in Total Joint Arthroplasty

Recruiting
3
460
US
Dronabinol, Marinol, Placebo, Lactose
Colorado Joint Replacement
Osteoarthritis, Knee
02/24
02/25
2022-004238-20: BONG: Breathlessness and alternatives to Opioid treatment in Non-malign Groups of severe lung disease Lindring af svær åndenød med Dronabinol hos patienter med svær Kronisk Obstruktiv Lungesygdom (KOL)

Not yet recruiting
3
30
Europe
Dronabinol kapsel 2,5 mg, Capsule, soft
Vejle Hospital, Vejle Hospital
COPD, Chronic obstructive pulmonary disease, Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09]
 
 
BONG, NCT06473701: Reducing Breathlessness With Dronabinol in COPD Patients

Recruiting
3
30
Europe
Dronabinol 2.5mg Capsule, Delta9-tetrahydrocannabinol, Placebo
Vejle Hospital, Region of Southern Denmark, Odense Patient Data Explorative Network, University of Southern Denmark, University of Aarhus
COPD, Breathlessness, Cannabis
04/26
07/26
POINT, NCT06175273: Pediatric Oncology Nutrition Intervention Trial

Recruiting
2/3
45
US
Oral Nutrition Supplement, Tube Feed, Cyproheptadine, Olanzapine, Standard of Care
Corey Hawes, National Center for Advancing Translational Sciences (NCATS)
Pediatric Cancer, Nutrition Related Cancer, Nutrition Aspect of Cancer, Muscle Loss, Malnutrition, Child
03/25
03/25
NAVE-Sci-001, NCT05239390: SCI-110 for Alzheimer Disease and Agitation

Recruiting
2a
20
RoW
SCI -110, Dronabinol and PEA
The Israeli Medical Center for Alzheimer's
Alzheimer Disease
06/23
06/23
ACTRN12619000491167: Tetrahydrocannabinol for cancer-related anorexia

Recruiting
2
250
 
Palliative Care Clinical Studies Collaborative, NSW Health
Cancer-related anorexia
 
 
2006-004482-33: Investigating the acute effects of THC on functional brain systems

Ongoing
2
21
Europe
Dronabinol,
University Medical Center Utrecht
This research project will be performed with healthy volunteers in order to determine whether THC modulates activity in functional brain systems.
 
 
2017-004226-15: Can-ArtEffect and safety of using Canabis derivatives for the treatment of pain in patients with inflammatory Arthritis, such as reumatoid arthritis and ankylosing spondylitis, the latter being a type of arthritis that causes a long term inflammation of the joints of the spine. A randomized, double blinded, placebo controlled trial, i.e. in this drug trial, a control group is given a placebo while another group is given the Cannabis derivative being studied. Can-ArtEffekt og sikkerhed ved anvendelse af Canabis-derivater til behandling af smerte hos patienter med inflammatorisk arthritis, såsom rheumatoid arthritis og ankyloserende spondylitis (sidstnævnte er en type arthritis, der forårsager langvarig betændelse i rygsøjlen og bækkenet).En randomiseret, dobbeltblindet, placebokontrolleret forsøg, dvs. i denne lægemiddelforsøg, gives en kontrolgruppe en placebo, mens en anden gruppe får substansen, der undersøges, dvs. Cannabis derivatet.

Ongoing
2
180
Europe
Cannabidiol tablet 10 mg, Dronabinol capsule 2.5. mg, Tablet, Capsule
King Christian 10th Hospital for Rheumatology, The Danish Rheumatism Association, The Region of Southern Denmark
Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS), RA and AS are autoimmune diseases. In RA the immune system attacks the membranes lining the joints, typically initially in small joints. AS affects the joints of the spine and the pelvic girdle., Diseases [C] - Musculoskeletal Diseases [C05]
 
 
2017-004823-66: Early-life stress, the endocannabinoid system, and fear memory extinction

Ongoing
2
48
Europe
Namisol, Hydrocortison CF, ECP002A, RVG 50730, Tablet, Hydrocortison CF
Radboudumc, Radboudumc
healthy volunteers gezonde vrijwilligers, intended indication: posttraumatic stress disorder (PTSD) beoogde indicatie: posttraumatic stress disorder (PTSD), Psychiatry and Psychology [F] - Mental Disorders [F03]
 
 
2018-000014-38: A Phase IIa Study to Determine the Safety, Tolerability and Efficacy of a daily oral dose of THX-110 in Adult Patients with Tourette Syndrome (TS)

Not yet recruiting
2
60
Europe
THX-110 [Dronabinol], THX-110 [PEA (Palmitoylethanolamide)], Capsule, soft, Tablet, Dronabinol Capsules, USP
Therapix Biosciences Ltd., Therapix Biosciences Ltd.
Tourette Syndrome, Neuropsychiatric disorder characterized by multiple motor or vocal tics., Diseases [C] - Nervous System Diseases [C10]
 
 
2021-000305-24: Evaluating the effects of a novel drug on THC effects

Ongoing
2
100
Europe
ANEB001, NAMISOL®, ANEB001, Capsule, soft, Tablet
Anebulo pharmaceuticals, Inc., Anebulo pharmaceuticals, Inc.
THC intoxication, THC overdose, Not possible to specify
 
 
NCT04596826 / 2019-003089-42: The Effect of Dronabinol on Ocular Hemodynamics in Patients With Primary Open Angle Glaucoma

Recruiting
2
100
Europe
Dronabinol 5 MG, Dronabinol 10 MG, Placebo
Medical University of Vienna
Retinal Blood Flow
10/23
10/23
THC-AD, NCT02792257: Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease

Completed
2
75
US
Dronabinol (Marinol®), Placebo
Johns Hopkins University, Mclean Hospital, Miami Jewish Health, National Institute on Aging (NIA), Tufts Medical Center
Alzheimer's Disease
05/24
05/24
DARP, NCT06454669: Dronabinol as an Adjunct for Reducing Pain

Recruiting
2
75
US
Dronabinol, Marinol, delta-9-tetrahydrocannabinol, Placebo
Christopher D. Verrico
Low Back Pain, Chronic Pain, Back Injuries
12/26
12/27
NCT06446479: Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Recruiting
2
28
US
Dronabinol Pill, Placebo
University of Colorado, Denver, National Institute on Alcohol Abuse and Alcoholism (NIAAA), Colorado State University
Cannabis Use Disorder
06/26
06/26
NCT06834997: Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's Hospital

Not yet recruiting
2
75
US
Dronabinol Capsules, Marinol, delta-9-tetrahydrocannabinol, Placebo
Baylor College of Medicine
Endometriosis, Endometriosis Related Pain, Endometriosis, Pain
12/27
05/28
NCT05477875: Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control

Completed
2
35
US
oral cannabinoid, dronabinol, oral codeine/acetaminophen
University of Florida, Consortium for Medical Marijuana Clinical Outcomes Research
Photorefractive Keratectomy, Myopia, Hyperopia
01/25
01/25
 

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