| Reasanz (serelaxin) / Novartis |
2013-005054-30: A study aiming at evaluating the affect of a new drug serelaxin on the capacity of work of the left chamber of the heart and its impact on the outcome in patients with acute heart failure. |
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| Ongoing | 3 | 36 | Europe | Serelaxin, RLX030, Solution for infusion | Ospedale San Raffaele s.r.l., Ospedale San Raffaele Srl | Acute Heart Failure, Acute shortness of breath due to heart failure, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2014-002257-19: Study to evaluate the effect of using ecocargiografia serelaxina in the functioning of the right ventricle. Estudio para evaluar mediante ecocargiografia el efecto de serelaxina en el funcionamiento del ventriculo derecho. |
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| Ongoing | 3 | 60 | Europe | Serelaxina, Solution for infusion | Fundación para la Investigación Biomédica del Hospital Ramón y Cajal, Fundación para la Investigación Biomédica del Hospital Ramón y Cajal | ICA hospitalized patients with high normal blood pressure, and mild to moderate renal failure at the time of selection Pacientes hospitalizados por ICA, con presión arterial normal a elevada, e insuficiencia renal leve a moderada en el momento de la selección., Patients with acute heart failure Pacientes con insuficiencia cardíaca aguda, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| AZD3427 / AstraZeneca |
Re-PHIRE, NCT05737940: A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2 |
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| Recruiting | 2 | 220 | Europe, Canada, Japan, US, RoW | AZD3427, Placebo | AstraZeneca, Parexel | Pulmonary Hypertension (World Health Organization Group 2), Heart Failure | 04/25 | 08/25 | | |
Re-PERFUSE, NCT06611423: AZD3427 Effects on Renal Perfusion in Heart Failure Patients With Reduced Ejection Fraction and Renal Impairment |
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| Recruiting | 1 | 12 | Europe | AZD3427, AZD3427 Placebo, Dopamine, Radiolabelled ligand, Saline | AstraZeneca, CTC Clinical Trial Consultants AB, Karolinska Institutet | Heart Failure With Reduced Ejection Fraction (HFrEF), Renal Impairment | 09/25 | 09/25 | | |
