β adrenergic blocker 
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58 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
atenolol / Generic mfg.
ChiCTR-ONC-11001645: Nitrendipine/atenolol combination tablets anti-hypertension treatment in community healthcare

Completed
4
9000
 
The enrolled patients aged 18-70 will be treated with nitrendipine/atenolol combination tablets for 6 months(some of them will be treated for 12 months). The initial dose comprised two tablets of nitrendipine(5 mg)/atenolol(10 mg) between 8:00 am and 10:00 am once a day.; If the blood pressure is higher than that of baseline at the end of the second week, the drugs may increase to 3 tablets(taking an additional tablet of drug at about 18:00 pm). If the blood pressure are poor controlled (≥ 140/90 mmHg) at the end of the fourth week, the drugs taken in the afternoon may increase to 2 tablets.; If the blood pressure are poor controlled (≥ 140/90 mmHg) at the end of the second month, the patients may take other antihypertensive drugs (other CCB and β-blockers are not allowed to take). If dose-related intolerance symptoms, suspected or definite low blood pressure occur in patients,the drugs taken may be reduced gradually.
The Beijing Hypertension League Institute; Fuwai Hospital PUMC & CAMS, Jiangsu Jiberer Pharmaceutical Company Limited
Primary hypertension
 
 
2004-004329-90: EARLY METABOLIC CHANGES WITH THIAZIDE OR BETA BLOCKER THERAPY FOR ESSENTIAL HYPERTENSION (MAIN STUDY).

Ongoing
4
66
Europe
ATENOLOL, BENDROFLUMETHIAZIDE, Nebivolol Hydrochloride, Amiloride hydrochloride, Hydrochlorothiazide, N/A, PL 0289/0172, Nebilet, No trade name, Apo-Hydro, Nebilet, No trade name, Apo-Hydro
CAMBRIDGE UNIVERSITY HOSPITALS FOUNDATION NHS TRUST
ESSENTIAL HYPERTENSION
 
 
2005-001214-40: A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivity

Ongoing
4
50
Europe
Atenolol, Atenolol, Nebliet, Atenolol, Nebliet
Imperial College London
Hypertension
 
 
2007-003549-33: Efectos de Nebivolol y Atenolol sobre la Presión Central Aórtica en Pacientes Hipertensos

Ongoing
4
152
Europe
Lovibon 5 mg, Blokium 50 mg y Blokium 100 mg, Hidrosaluretil, Lovibon 5 mg, Blokium 50 mg y Blokium 100 mg, Hidrosaluretil
Laboratorios MENARINI, S. A.
Hipertensión esencial leve o moderada
 
 
2006-006733-41: Effet de l’association fixe amlodipine/valsartan sur la Pression artérielle centrale chez des hypertendus essentiels non contrôlés par amlodipine 5mg

Ongoing
4
532
Europe
Exforge, Amlor, Atenolol, Exforge, Amlor, Atenolol
Novartis Pharma S.A.S.
Hypertension artérielle essentielle
 
 
2008-007516-15: Comparaison des effets du nébivolol et de l\'aténolol sur la fonction endothéliale vasomotrice des artères de conductance lors de l\'hypertension artérielle essentielle

Ongoing
4
100
Europe
NEBILOX, ATENOLOL BIOGARAN 50 mg, NEBILOX, ATENOLOL BIOGARAN 50 mg
Laboratoires NEGMA
Hypertension artérielle
 
 
2008-003773-41: Effect of heart rate and autonomic nervous system modulation on inflammatory state and peripheral vascular function in patients with type 2 diabetes.

Ongoing
4
150
Europe
PROCORALAN*56CPR RIV 5MG ALL/P, TENORMIN*42CPR 100MG, PROCORALAN*56CPR RIV 5MG ALL/P, TENORMIN*42CPR 100MG
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
diabetes type 2
 
 
2011-006090-25: The impact of heart rate on the effects of antihypertensive therapy on central and peripheral blood pressure Südame löögisageduse mõju vererõhuravimite mõjule tsentraalsele ja perifeersele vererõhule

Ongoing
4
100
Europe
ivabradine, nebivolol, atenolol, Procoralan, Nebilet, Atenolol-ratiopharm, Procoralan, Nebilet, Atenolol-ratiopharm
Tartu Ülikooli kardioloogiakliinik, Eesti Teadusfond
Patients with dual chamber (atrium and ventricle) cardiac pacemaker placed due to sick sinus syndrome (at least 1 month after implantation) Patsiendid, kellele on siinussõlme nõrkuse sündroomi tõttu varasemalt paigaldatud koja ja vatsakese elektroodiga kardiostimulaator (vähemalt 1 kuu peale implantatsiooni)
 
 
NCT04767061: Impact of Beta-blockers on Physical Function in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, The New York Community Trust
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/22
04/23
NCT05106179: The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Enrolling by invitation
4
1000
RoW
Atenolol Pill, Propranolol Pill
Center for Vascular Pathology, Moscow
Spinal Tumor, Spinal Hemangioma, Beta Blocker Toxicity
12/22
12/23
ChiCTR2100049628: Clinical study of arolol hydrochloride in the treatment of middle-aged and young people with essential hypertension

Not yet recruiting
4
72
 
Arotinolol hydrochloride ;Metoprolol succinate ;Atenolol
The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, Sponsorship
Essential Hypertension
 
 
NCT04757584: Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, National Institute on Aging (NIA)
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/23
04/23
NCT04931108: The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability.

Recruiting
4
32
RoW
Nitrendipine/Atenolol, Nitrendipine and Atenolol Tablets, Nitrendipine, Nitrendipine Tablets, Atenolol, Atenolol Tablets
Shanghai Jiao Tong University School of Medicine
Hypertension
06/23
06/23
NCT04914234: Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries

Recruiting
4
60
RoW
Atenolol Succinate Oral Tablet, Tenormin tablets, Metoprolol Succinate Oral Tablet, Seloken ZOC tablets
Damanhour Teaching Hospital
Hypotension Drug-Induced
07/25
07/25
NCT03596385 / 2017-002485-40: TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"

Completed
4
8507
Europe
Beta blocker, atenolol, bisoprolol, carvedilol, metoprolol, nevibolol.
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Myocardial Infarction
01/25
01/25
2009-011156-21: Effects of beta-blockers on exercise performance in uncomplicated hypertension Valutazione degli effetti della terapia beta-bloccante sulla tolleranza allo sforzo nell\'ipertensione arteriosa non complicata

Ongoing
3
60
Europe
CONGESCOR*50CPR RIV 10MG, ATENOLOLO TEVA*50CPR 100MG, CONGESCOR*50CPR RIV 10MG, ATENOLOLO TEVA*50CPR 100MG
FONDAZIONE MONZINO CENTRO CARDIOLOGICO, Centro Cardiologico
Non complicated arterial hypertension Ipertensione arteriosa non complicata
 
 
TREAT-SVDs, NCT03082014 / 2016-002920-10: Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function

Terminated
3
101
Europe
Amlodipine, Losartan, Atenolol
Ludwig-Maximilians - University of Munich, University of Edinburgh, Maastricht University Medical Center, UMC Utrecht, University of Oxford
Cerebral Small Vessel Diseases
07/22
07/22
APO, NCT04905277: Atenolol for the Prevention of Osteoporosis

Active, not recruiting
2
420
US
Atenolol 50 MG, Atenolol, Placebo
Sundeep Khosla, M.D., Columbia University, MaineHealth, University of California, San Francisco
Healthy
03/26
03/26
RaP-AF, NCT04513509: Rate Control in Patients With Atrial Fibrillation

Not yet recruiting
N/A
50
RoW
Atenolol, Bisoprolol, Metoprolol, Nebivolol, Propranolol, Diltiazem, Verapamil, digoxin
National Taiwan University Hospital
Atrial Fibrillation, Rate Control, Cardiopulmonary Exercise Test
06/22
06/22
NCT04755764: Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

Recruiting
N/A
60
US
Labetalol, Normodyne, Trandate, Atenolol, Tenormin, Nifedipine, Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL
Marshall University
Systolic Hypertension, Pregnancy Related, Diastolic Hypertension, Cardiac Output, Low, Cardiac Output, High
04/24
12/24
NCT05794997: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol

Active, not recruiting
N/A
817337
US
Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol
Brigham and Women's Hospital, National Institute on Aging (NIA), Rutgers University, Johns Hopkins University
Hypertension
01/23
12/23
NCT04224675: Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms

Not yet recruiting
N/A
424
NA
Atenolol, Captopril
Onassis Cardiac Surgery Centre
Aneurysm
03/23
03/23
NCT06505668: Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.

Recruiting
N/A
40
RoW
Atenolol 25 mg, Arm A, Ivabradine 10mg, Arm B
All India Institute of Medical Sciences, Bhubaneswar
Treatment Resistant Schizophrenia, Clozapine Adverse Reaction, Heart Rate Variability, Tachycardia
06/25
06/25
NCT06670690: Comparison Between Atenolol,Propnalol and Ivabradine

Completed
N/A
120
RoW
Atenolol 50 MG, Propranolol Pill, Ivabradine
Menoufia University
Intraoperative Bleeding
09/23
10/23
NCT05543122: Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Completed
N/A
39
Canada
either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe, Typical brand names include, but not limited to: Tenoretic, Wellbutrin, Zyban, Briviact, Cipralex, Lexapro, Diflucan, Vimpat, Lamictal, Keppra, Trexall, Xatmep, Ezetrol, Nexlizet
The Hospital for Sick Children, St. Justine's Hospital, University of Waterloo
Breast Feeding
12/23
03/24
ACTRN12607000109404: Stroke Prevention by Antihypertensive Drugs (SPREAD) Trial

Active, not recruiting
N/A
6000
 
Cardiovascular Institute, Chinese Academy of Medical Sciences, the Ministry of Science and Technology of China
Hypertension
 
 
sotalol / Generic mfg.
2009-011163-36: Ablación de sustrato de las taquicardias ventriculares monomórficas versus fármacos antiarrítmicos en pacientes con descargas apropiadas de desfibrilador automático implantable

Ongoing
4
180
Europe
TRANGOREX 200 mg comprimidos, CARVEDILOL SANDOZ 25 mg comprimidos, SOTALOL TEVA 80 mg Comprimidos, TRANGOREX 200 mg comprimidos, CARVEDILOL SANDOZ 25 mg comprimidos, SOTALOL TEVA 80 mg Comprimidos
FUNDACION PARA LA INVESTIGACION BIOMEDICA HOSPITAL GREGORIO MARAÑON
PREVENCION DE ARRITMIAS EN CARDIOPATIA ISQUEMICA
 
 
NCT03895411: Efficacy and Safety of Sotalol in Children With Arrhythmia

Not yet recruiting
4
500
RoW
sotalol, Propafenone, betaloc
Shengjing Hospital
Arrhythmia
12/20
12/22
DASH-AF, NCT04473807: Feasibility and Safety of IV Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy

Recruiting
4
80
US
Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients with Atrial Fibrillation, Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy
Kansas City Heart Rhythm Research Foundation, Texas Cardiac Arrhythmia Research Foundation, Munson Medical Center
Arrhythmias, Cardiac, Atrial Fibrillation
04/22
06/22
2018-001518-13: Elimination of ventricular premature beats and ventricular tachycardia with catheter ablation versus optimal anti-arrhythmic drug treatment Eliminatie van premature ventriculaire complexen met catheter ablatie versus optimale medicamenteuze behandeling met anti-arritmica.

Not yet recruiting
4
180
Europe
Sotalol, Verapamil, Flecainide, Tablet
Maatschap Cardiologie Zwolle, Isala Zwolle
Premature ventricular beats, ventricular ectopy, ventricle tachycardia Premature ventriculaire complexen, ventriculaire extrasystolen, ventriculaire tachycardie, Premature cardiac beat Ventriculaire extrasystole (VES), Diseases [C] - Cardiovascular Diseases [C14]
 
 
Sotalol, NCT05418036: Safety Assessment for Protocol in Outpatient Unit

Recruiting
4
110
RoW
Sotalol Oral Tablet, sotalol choridrate
University of Sao Paulo General Hospital
Supraventricular Arrhythmia, Ventricular Arrythmia, Proarrhythmia, Antiarrhythmic Drug Adverse Reaction
02/23
06/23
VANISH2, NCT02830360: Antiarrhythmics or Ablation for Ventricular Tachycardia 2

Completed
4
416
Europe, Canada, US
Antiarrythmic Drug Therapy, Amiodarone (Cordarone) or Sotalol (Sotacor), Catheter ablation, VT ablation
John Sapp, Heart and Stroke Foundation of Canada, Abbott Medical Devices, Biosense Webster, Inc., Ottawa Heart Institute Research Corporation, Canadian Institutes of Health Research (CIHR), Cardiac Arrhythmia Network of Canada, Abbott, Nova Scotia Health Authority
Ventricular Tachycardia (VT)
06/24
06/24
NCT02347111: Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

Recruiting
4
162
US
Flecainide, Sotalol
University of Illinois at Chicago, Medtronic
Atrial Fibrillation
06/25
06/25
2015-005743-14: Fetal atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial

Ongoing
3
600
Europe
Flecainide acetate, sotalol, Digoxin, Tablet, Injection, flecainide acetate, SOTALOL, Digoxin
St Georges University Hospital NHS Foundation Trust
Fetal atrial flutter without hydrops, supraventricular tachycardia without hydrops and supraventricular tachycardia with hydrops, fetal heart rhythm abnormalities, Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
 
 
2021-006614-37: First-line catheter ablation for early treatment of Persistent (ongoing unless cardioverted) Atrial Fibrillation (AF) – a randomized study comparing isolation of pulmonary veins triggering AF using a Cryoballoon versus antiarrhythmic medication. Kryoablation som förstahandsval för tidig behandling av persisterande (fortgående såvida inte elektrisk eller medicinsk konvertering ges) förmaksflimmer - en randomiserad studie som jämför lungvensisolering med rytmstabiliserande läkemedel.

Ongoing
3
220
Europe
Tablet, tambocor, multaq, rytmonorm, sotalol
Carina Blomström Lundqvist, Swedish Research Council, Familjen Erling-Perssons Stiftelse, Swedish Heart and Lung Foundation
Persistent symptomatic atrial fibrillation Persisterande symptomatiskt förmaksflimmer, Irregular heart rhythm proved to be persistent symptomatic atrial fibrillation (chaotic rhythm in the hearts atria) that requires electrical or medical cardioversion to normal rhythm. Oregelbunden hjärtrytm som beror på ihållande förmaksflimmer som kräver medicinsk eller elektrisk konvertering för omslag till sinus rytm., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]
 
 
2021-002487-46: Prophylactic frequent premature ventricular complexeS sUPPression on left ventriculaR function impairmEnt in aSymptomatic patientSSUPPRESS Traitement prophylactique des extrasystoles ventriculaires fréquentes sur l’incidence de la cardiomyopathie rythmique induite chez les patients asymptomatiques

Not yet recruiting
3
298
Europe
Bisoprolol, Nebivolol, Flécaïnide, Verapamil, Diltiazem, Amiodarone, Sotalol, PROPAFENONE, C01BC03
Assistance Publique - Hôpitaux de Paris, PHRC
Premature ventricular contractions (PVCs) Contractions ventriculaires prématurées (PVC), Premature ventricular contractions (PVCs) Contractions ventriculaires prématurées (PVC), Diseases [C] - Cardiovascular Diseases [C14]
 
 
NCT02624765: Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)

Completed
3
105
Europe, Canada, US, RoW
Digoxin (monotherapy), Sotalol (monotherapy), Flecainide (monotherapy), Digoxin (dual therapy), Sotalol (dual therapy), Flecainide (dual therapy)
Edgar Jaeggi, Canadian Institutes of Health Research (CIHR)
Fetal Atrial Flutter Without Hydrops, Fetal Supraventricular Tachycardia Without Hydrops, Fetal Supraventricular Tachycardia With Hydrops
03/24
03/24
NCT05939076: First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation

Not yet recruiting
3
220
Europe
Pulmonary vein isolation, dronedarone - Multaq™ OR flecainide - Tambocor™ OR propafenone - Rytmonorm™ OR sotalol - Sotacor™
Region Örebro County, The Swedish Research Council, Erling-Persson Stiftelse, Swedish Heart Lung Foundation, Uppsala University
Atrial Fibrillation, Persistent
12/27
12/28
EARLY-AF, NCT02825979: Early Aggressive Invasive Intervention for Atrial Fibrillation

Active, not recruiting
N/A
303
Canada
Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy, sotalol, flecainide, propafenone, dronedarone
Jason Andrade, Ottawa Heart Institute Research Corporation, Medtronic, Baylis Medical Company
Atrial Fibrillation
09/22
11/22
DOFEGEN, NCT02439658: Genetics of QT Prolongation With Antiarrhythmics

Recruiting
N/A
1000
US
Dofetilide and/or sotalol, Tikosyn
Massachusetts General Hospital, Mayo Clinic, The Cleveland Clinic, University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)
Long QT Syndrome, Drug Toxicity
12/22
04/23
ECTOPIA, NCT03845010 / 2018-001518-13: Elimination of VPB With Ablation Versus Anti-arrhythmic Drug Treatment

Completed
N/A
22
Europe
Sotalol, Flecainide and verapamil, Catheter ablation
Maatschap Cardiologie Zwolle, Isala Zwolle
Ventricular Premature Beats
01/23
01/23
Cryo-InitialAF, NCT04942834: Using Cryoballoon Ablation as Initial Treatment for Persistent Atrial Fibrillation

Recruiting
N/A
286
RoW
Antiarrhythmic drug including Propafenone, Sotalol, Dronedarone and Amiodarone, cryoballoon ablation
Ruijin Hospital
Atrial Fibrillation, Persistent, Arrhythmias, Cardiac
07/25
01/26
PEAKS, NCT05247320: Prospective Evaluation Analysis and Kinetics Registry

Completed
N/A
167
US
Sotalol Injection
University of Utah, AltaThera Pharmaceuticals, LLC
Atrial Arrhythmia
08/23
08/23
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting
N/A
484
Europe, Canada, US, RoW
FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific Corporation
Persistent Atrial Fibrillation
02/26
12/27
EDearly AF, NCT06322017: Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation

Recruiting
N/A
294
Europe
Rhythm control by Pulmonary Vein Isolation (PVI) procedure, Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin)
Nantes University Hospital
Atrial Fibrillation
04/28
04/28
NCT06669299: Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies

Not yet recruiting
N/A
51
Europe
Re-Do ventricular tachycardia ablation, Antiarrhythmic Drug Therapy (amiodarone, sotalol, or mexiletine)
IRCCS Ospedale San Raffaele
Ventricular Tachycardia (VT)
12/27
12/27
ChiCTR2400088934: The prevention effect of Sotalol for post-operative atrial fibrillation after coronary artery bypass grafting: a randomized contrlled trial

Recruiting
N/A
340
 
Sotalol ; Metoprolol
Fuwai Hospital, Chinese Academy of Medical Sciences; Fuwai Hospital, Chinese Academy of Medical Sciences, National High Level Hospital Clinical Research Funding
coronary artery disease
 
 
dronedarone / Generic mfg.
2010-019442-87: Dronedarone in pacemaker patients with paroxysmal atrial fibrillation

Ongoing
4
50
Europe
Dronedarone - Multaq, Multaq, Multaq
East Sussex NHS Trust
Paroxysmal atrial fibrillation
 
 
EDORA, NCT04704050: Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence

Terminated
4
22
US
dronedarone 400 mg Oral Tablet, Multaq®, Placebo
Tulane University School of Medicine, University of Washington, Marrek, INC, Sanofi, Preventice, Mckesson
Atrial Fibrillation, Atrial Fibrillation Recurrent
12/22
12/22
ChiCTR2200062928: Effects of oral dronedarone hydrochloride tablets on NOACs concentrations in patients with paroxysmal or persistent atrial fibrillation: a randomized, controlled, single-center clinical study

Not yet recruiting
4
75
 
Amiodarone 200mg qd combined with dabigatran 110mg bid for 1 month ;Dronedarone 400mg bid plus dabigatran 110mg bid for 1 month ;Dabigatran 150mg bid for 1 month ;Amiodarone 200mg qd combined with rivaroxaban 15mg qd for 1 month ;Dronedarone 400mg bid combined with rivaroxaban 15mg qd for 1 month ;Rivaroxaban 20mg qd for 1 month
The First Hospital of China Medical University; The First Hospital of China Medical University, The CSPC Ouyi Pharmaceutical Co., Ltd
Atrial fibrillation
 
 
ChiCTR2100052758: A multicenter, randomized controlled clinical study of oral dronedarone hydrochloride tablets after catheter ablation in patients with persistent atrial fibrillation to reduce the first recurrence of atrial fibrillation

Recruiting
4
200
 
Dronedarone Hydrochloride Tablets ;Amiodarone
Shenzhen Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences; Shenzhen Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences, The CSPC Ouyi Pharmaceutical Co., Ltd.
Atrial fibrillation
 
 
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation

Completed
4
339
US
Dronedarone, Multaq
American Heart Association, Duke Clinical Research Institute, Sanofi
Atrial Fibrillation
01/24
06/24
ChiCTR2200066977: Comparison of the effectiveness and safety of dronedarone and amiodarone for preventing atrial fibrillation recurrence after catheter ablation: an open label study

Not yet recruiting
4
280
 
Dronedarone ;Amidarone
The First Affiliated Hospital, Zhejiang University School of Medicine; The First Affiliated Hospital, Zhejiang University School of Medicine, Shijiazhuang Pharmaceutical Group Ouyi Pharmaceutical Co., Ltd
Atrial Fibrillation
 
 
DORIS, NCT05655468: Effect of Prolonged Use of Dronedarone on Recurrence in Patients With Non-paroxysmal Atrial Fibrillation After Radiofrequency Ablation

Recruiting
4
268
RoW
Dronedarone, Placebo
Shanghai East Hospital
Atrial Fibrillation
04/25
11/25
ChiCTR2300069986: Effect of oral dronedarone hydrochloride tablets on rivaroxaban serum concentration in patients with paroxysmal and persistent atrial fibrillation：A randomized, controlled, single-center clinical study

Not yet recruiting
4
60
 
Dronedarone 400mg bid, Rivaroxaban 15mg qd, 1 month ;Rivaroxaban 15mg qd, 1 month
The Second Affiliated Hospital of the Military Medical University of the PLA Air Force; The Second Affiliated Hospital of the Military Medical University of the PLA Air Force, The CSPC Ouyi Pharmaceutical Co.，Ltd
Atrial Fibrillation
 
 
ChiCTR2500096575: Study on the effect of Shensong Yangxin capsule combined with dronedarone on maintaining sinus rhythm after radiofrequency ablation for persistent atrial fibrillation

Not yet recruiting
4
120
 
The total course of treatment for Shensong Yangxin Capsules 1.6g tid+Dronedarone 400mg bid orally was 3 months, and later changed to Shensong Yangxin Capsules 1.6g tid to maintain for 1 year.; Dronedarone 400mg bid for a total course of 3 months
Mianyang 404 Hospital; Mianyang 404 Hospital, raise independently
atrial fibrillation
 
 
ChiCTR2400086750: Safety and efficacy of dronedarone combined with sorafenib in the treatment of advanced hepatocellular carcinoma: a phase I/II exploratory study

Not yet recruiting
1/2
46
 
Dronedarone combined with sorafenib
The First Affiliated Hospital of Army Medical University, PLA; The First Affiliated Hospital of Army Medical University, PLA, Self-funded
hepatocellular carcinoma
 
 
DMT-PVC I, ChiCTR2200058438: Dronedarone versus metoprolol in the treatment of idiopathic RVOT premature ventricular complexes: a multicenter, parallel, open label, randomized controlled trial-

Not yet recruiting
N/A
110
 
Dronedarone 400mg bid (morning and evening with meals), for 3 months ;Metoprolol, 25mg bid, for 3 months
The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital); The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital), The CSPC Ouyi Pharmaceutical Co., Ltd
Premature ventricular complexes
 
 
Sotylize (sotalol oral solution) / Azurity Pharma
No trials found
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
atenolol / Generic mfg.
ChiCTR-ONC-11001645: Nitrendipine/atenolol combination tablets anti-hypertension treatment in community healthcare

Completed
4
9000
 
The enrolled patients aged 18-70 will be treated with nitrendipine/atenolol combination tablets for 6 months(some of them will be treated for 12 months). The initial dose comprised two tablets of nitrendipine(5 mg)/atenolol(10 mg) between 8:00 am and 10:00 am once a day.; If the blood pressure is higher than that of baseline at the end of the second week, the drugs may increase to 3 tablets(taking an additional tablet of drug at about 18:00 pm). If the blood pressure are poor controlled (≥ 140/90 mmHg) at the end of the fourth week, the drugs taken in the afternoon may increase to 2 tablets.; If the blood pressure are poor controlled (≥ 140/90 mmHg) at the end of the second month, the patients may take other antihypertensive drugs (other CCB and β-blockers are not allowed to take). If dose-related intolerance symptoms, suspected or definite low blood pressure occur in patients,the drugs taken may be reduced gradually.
The Beijing Hypertension League Institute; Fuwai Hospital PUMC & CAMS, Jiangsu Jiberer Pharmaceutical Company Limited
Primary hypertension
 
 
2004-004329-90: EARLY METABOLIC CHANGES WITH THIAZIDE OR BETA BLOCKER THERAPY FOR ESSENTIAL HYPERTENSION (MAIN STUDY).

Ongoing
4
66
Europe
ATENOLOL, BENDROFLUMETHIAZIDE, Nebivolol Hydrochloride, Amiloride hydrochloride, Hydrochlorothiazide, N/A, PL 0289/0172, Nebilet, No trade name, Apo-Hydro, Nebilet, No trade name, Apo-Hydro
CAMBRIDGE UNIVERSITY HOSPITALS FOUNDATION NHS TRUST
ESSENTIAL HYPERTENSION
 
 
2005-001214-40: A trial to compare the effects of nebivolol versus atenolol on various cardiovascular measurements including insulin sensitivity

Ongoing
4
50
Europe
Atenolol, Atenolol, Nebliet, Atenolol, Nebliet
Imperial College London
Hypertension
 
 
2007-003549-33: Efectos de Nebivolol y Atenolol sobre la Presión Central Aórtica en Pacientes Hipertensos

Ongoing
4
152
Europe
Lovibon 5 mg, Blokium 50 mg y Blokium 100 mg, Hidrosaluretil, Lovibon 5 mg, Blokium 50 mg y Blokium 100 mg, Hidrosaluretil
Laboratorios MENARINI, S. A.
Hipertensión esencial leve o moderada
 
 
2006-006733-41: Effet de l’association fixe amlodipine/valsartan sur la Pression artérielle centrale chez des hypertendus essentiels non contrôlés par amlodipine 5mg

Ongoing
4
532
Europe
Exforge, Amlor, Atenolol, Exforge, Amlor, Atenolol
Novartis Pharma S.A.S.
Hypertension artérielle essentielle
 
 
2008-007516-15: Comparaison des effets du nébivolol et de l\'aténolol sur la fonction endothéliale vasomotrice des artères de conductance lors de l\'hypertension artérielle essentielle

Ongoing
4
100
Europe
NEBILOX, ATENOLOL BIOGARAN 50 mg, NEBILOX, ATENOLOL BIOGARAN 50 mg
Laboratoires NEGMA
Hypertension artérielle
 
 
2008-003773-41: Effect of heart rate and autonomic nervous system modulation on inflammatory state and peripheral vascular function in patients with type 2 diabetes.

Ongoing
4
150
Europe
PROCORALAN*56CPR RIV 5MG ALL/P, TENORMIN*42CPR 100MG, PROCORALAN*56CPR RIV 5MG ALL/P, TENORMIN*42CPR 100MG
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
diabetes type 2
 
 
2011-006090-25: The impact of heart rate on the effects of antihypertensive therapy on central and peripheral blood pressure Südame löögisageduse mõju vererõhuravimite mõjule tsentraalsele ja perifeersele vererõhule

Ongoing
4
100
Europe
ivabradine, nebivolol, atenolol, Procoralan, Nebilet, Atenolol-ratiopharm, Procoralan, Nebilet, Atenolol-ratiopharm
Tartu Ülikooli kardioloogiakliinik, Eesti Teadusfond
Patients with dual chamber (atrium and ventricle) cardiac pacemaker placed due to sick sinus syndrome (at least 1 month after implantation) Patsiendid, kellele on siinussõlme nõrkuse sündroomi tõttu varasemalt paigaldatud koja ja vatsakese elektroodiga kardiostimulaator (vähemalt 1 kuu peale implantatsiooni)
 
 
NCT04767061: Impact of Beta-blockers on Physical Function in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, The New York Community Trust
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/22
04/23
NCT05106179: The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Enrolling by invitation
4
1000
RoW
Atenolol Pill, Propranolol Pill
Center for Vascular Pathology, Moscow
Spinal Tumor, Spinal Hemangioma, Beta Blocker Toxicity
12/22
12/23
ChiCTR2100049628: Clinical study of arolol hydrochloride in the treatment of middle-aged and young people with essential hypertension

Not yet recruiting
4
72
 
Arotinolol hydrochloride ;Metoprolol succinate ;Atenolol
The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, Sponsorship
Essential Hypertension
 
 
NCT04757584: Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Completed
4
9
US
Beta blockers, atenolol, betaxolol, bisoprolol, metoprolol, nebivolol, nadolol, propranolol, acebutolol, penbutolol, pindolol, carvedilol, labetalol, sotalol, metoprolol succinate, metoprolol tartrate
Weill Medical College of Cornell University, National Institute on Aging (NIA)
Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction, Cardiac Failure, Heart Disease
04/23
04/23
NCT04931108: The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability.

Recruiting
4
32
RoW
Nitrendipine/Atenolol, Nitrendipine and Atenolol Tablets, Nitrendipine, Nitrendipine Tablets, Atenolol, Atenolol Tablets
Shanghai Jiao Tong University School of Medicine
Hypertension
06/23
06/23
NCT04914234: Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries

Recruiting
4
60
RoW
Atenolol Succinate Oral Tablet, Tenormin tablets, Metoprolol Succinate Oral Tablet, Seloken ZOC tablets
Damanhour Teaching Hospital
Hypotension Drug-Induced
07/25
07/25
NCT03596385 / 2017-002485-40: TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"

Completed
4
8507
Europe
Beta blocker, atenolol, bisoprolol, carvedilol, metoprolol, nevibolol.
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Myocardial Infarction
01/25
01/25
2009-011156-21: Effects of beta-blockers on exercise performance in uncomplicated hypertension Valutazione degli effetti della terapia beta-bloccante sulla tolleranza allo sforzo nell\'ipertensione arteriosa non complicata

Ongoing
3
60
Europe
CONGESCOR*50CPR RIV 10MG, ATENOLOLO TEVA*50CPR 100MG, CONGESCOR*50CPR RIV 10MG, ATENOLOLO TEVA*50CPR 100MG
FONDAZIONE MONZINO CENTRO CARDIOLOGICO, Centro Cardiologico
Non complicated arterial hypertension Ipertensione arteriosa non complicata
 
 
TREAT-SVDs, NCT03082014 / 2016-002920-10: Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function

Terminated
3
101
Europe
Amlodipine, Losartan, Atenolol
Ludwig-Maximilians - University of Munich, University of Edinburgh, Maastricht University Medical Center, UMC Utrecht, University of Oxford
Cerebral Small Vessel Diseases
07/22
07/22
APO, NCT04905277: Atenolol for the Prevention of Osteoporosis

Active, not recruiting
2
420
US
Atenolol 50 MG, Atenolol, Placebo
Sundeep Khosla, M.D., Columbia University, MaineHealth, University of California, San Francisco
Healthy
03/26
03/26
RaP-AF, NCT04513509: Rate Control in Patients With Atrial Fibrillation

Not yet recruiting
N/A
50
RoW
Atenolol, Bisoprolol, Metoprolol, Nebivolol, Propranolol, Diltiazem, Verapamil, digoxin
National Taiwan University Hospital
Atrial Fibrillation, Rate Control, Cardiopulmonary Exercise Test
06/22
06/22
NCT04755764: Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

Recruiting
N/A
60
US
Labetalol, Normodyne, Trandate, Atenolol, Tenormin, Nifedipine, Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL
Marshall University
Systolic Hypertension, Pregnancy Related, Diastolic Hypertension, Cardiac Output, Low, Cardiac Output, High
04/24
12/24
NCT05794997: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol

Active, not recruiting
N/A
817337
US
Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol
Brigham and Women's Hospital, National Institute on Aging (NIA), Rutgers University, Johns Hopkins University
Hypertension
01/23
12/23
NCT04224675: Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms

Not yet recruiting
N/A
424
NA
Atenolol, Captopril
Onassis Cardiac Surgery Centre
Aneurysm
03/23
03/23
NCT06505668: Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial.

Recruiting
N/A
40
RoW
Atenolol 25 mg, Arm A, Ivabradine 10mg, Arm B
All India Institute of Medical Sciences, Bhubaneswar
Treatment Resistant Schizophrenia, Clozapine Adverse Reaction, Heart Rate Variability, Tachycardia
06/25
06/25
NCT06670690: Comparison Between Atenolol,Propnalol and Ivabradine

Completed
N/A
120
RoW
Atenolol 50 MG, Propranolol Pill, Ivabradine
Menoufia University
Intraoperative Bleeding
09/23
10/23
NCT05543122: Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Completed
N/A
39
Canada
either of Atenolol, Bupropion, Brivaracetam, Escitalopram, Fluconazole, Lacosamide, Lamotrigine, Levetiracetam, Methotrexate or Ezetimibe, Typical brand names include, but not limited to: Tenoretic, Wellbutrin, Zyban, Briviact, Cipralex, Lexapro, Diflucan, Vimpat, Lamictal, Keppra, Trexall, Xatmep, Ezetrol, Nexlizet
The Hospital for Sick Children, St. Justine's Hospital, University of Waterloo
Breast Feeding
12/23
03/24
ACTRN12607000109404: Stroke Prevention by Antihypertensive Drugs (SPREAD) Trial

Active, not recruiting
N/A
6000
 
Cardiovascular Institute, Chinese Academy of Medical Sciences, the Ministry of Science and Technology of China
Hypertension
 
 
sotalol / Generic mfg.
2009-011163-36: Ablación de sustrato de las taquicardias ventriculares monomórficas versus fármacos antiarrítmicos en pacientes con descargas apropiadas de desfibrilador automático implantable

Ongoing
4
180
Europe
TRANGOREX 200 mg comprimidos, CARVEDILOL SANDOZ 25 mg comprimidos, SOTALOL TEVA 80 mg Comprimidos, TRANGOREX 200 mg comprimidos, CARVEDILOL SANDOZ 25 mg comprimidos, SOTALOL TEVA 80 mg Comprimidos
FUNDACION PARA LA INVESTIGACION BIOMEDICA HOSPITAL GREGORIO MARAÑON
PREVENCION DE ARRITMIAS EN CARDIOPATIA ISQUEMICA
 
 
NCT03895411: Efficacy and Safety of Sotalol in Children With Arrhythmia

Not yet recruiting
4
500
RoW
sotalol, Propafenone, betaloc
Shengjing Hospital
Arrhythmia
12/20
12/22
DASH-AF, NCT04473807: Feasibility and Safety of IV Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy

Recruiting
4
80
US
Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients with Atrial Fibrillation, Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy
Kansas City Heart Rhythm Research Foundation, Texas Cardiac Arrhythmia Research Foundation, Munson Medical Center
Arrhythmias, Cardiac, Atrial Fibrillation
04/22
06/22
2018-001518-13: Elimination of ventricular premature beats and ventricular tachycardia with catheter ablation versus optimal anti-arrhythmic drug treatment Eliminatie van premature ventriculaire complexen met catheter ablatie versus optimale medicamenteuze behandeling met anti-arritmica.

Not yet recruiting
4
180
Europe
Sotalol, Verapamil, Flecainide, Tablet
Maatschap Cardiologie Zwolle, Isala Zwolle
Premature ventricular beats, ventricular ectopy, ventricle tachycardia Premature ventriculaire complexen, ventriculaire extrasystolen, ventriculaire tachycardie, Premature cardiac beat Ventriculaire extrasystole (VES), Diseases [C] - Cardiovascular Diseases [C14]
 
 
Sotalol, NCT05418036: Safety Assessment for Protocol in Outpatient Unit

Recruiting
4
110
RoW
Sotalol Oral Tablet, sotalol choridrate
University of Sao Paulo General Hospital
Supraventricular Arrhythmia, Ventricular Arrythmia, Proarrhythmia, Antiarrhythmic Drug Adverse Reaction
02/23
06/23
VANISH2, NCT02830360: Antiarrhythmics or Ablation for Ventricular Tachycardia 2

Completed
4
416
Europe, Canada, US
Antiarrythmic Drug Therapy, Amiodarone (Cordarone) or Sotalol (Sotacor), Catheter ablation, VT ablation
John Sapp, Heart and Stroke Foundation of Canada, Abbott Medical Devices, Biosense Webster, Inc., Ottawa Heart Institute Research Corporation, Canadian Institutes of Health Research (CIHR), Cardiac Arrhythmia Network of Canada, Abbott, Nova Scotia Health Authority
Ventricular Tachycardia (VT)
06/24
06/24
NCT02347111: Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

Recruiting
4
162
US
Flecainide, Sotalol
University of Illinois at Chicago, Medtronic
Atrial Fibrillation
06/25
06/25
2015-005743-14: Fetal atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial

Ongoing
3
600
Europe
Flecainide acetate, sotalol, Digoxin, Tablet, Injection, flecainide acetate, SOTALOL, Digoxin
St Georges University Hospital NHS Foundation Trust
Fetal atrial flutter without hydrops, supraventricular tachycardia without hydrops and supraventricular tachycardia with hydrops, fetal heart rhythm abnormalities, Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
 
 
2021-006614-37: First-line catheter ablation for early treatment of Persistent (ongoing unless cardioverted) Atrial Fibrillation (AF) – a randomized study comparing isolation of pulmonary veins triggering AF using a Cryoballoon versus antiarrhythmic medication. Kryoablation som förstahandsval för tidig behandling av persisterande (fortgående såvida inte elektrisk eller medicinsk konvertering ges) förmaksflimmer - en randomiserad studie som jämför lungvensisolering med rytmstabiliserande läkemedel.

Ongoing
3
220
Europe
Tablet, tambocor, multaq, rytmonorm, sotalol
Carina Blomström Lundqvist, Swedish Research Council, Familjen Erling-Perssons Stiftelse, Swedish Heart and Lung Foundation
Persistent symptomatic atrial fibrillation Persisterande symptomatiskt förmaksflimmer, Irregular heart rhythm proved to be persistent symptomatic atrial fibrillation (chaotic rhythm in the hearts atria) that requires electrical or medical cardioversion to normal rhythm. Oregelbunden hjärtrytm som beror på ihållande förmaksflimmer som kräver medicinsk eller elektrisk konvertering för omslag till sinus rytm., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]
 
 
2021-002487-46: Prophylactic frequent premature ventricular complexeS sUPPression on left ventriculaR function impairmEnt in aSymptomatic patientSSUPPRESS Traitement prophylactique des extrasystoles ventriculaires fréquentes sur l’incidence de la cardiomyopathie rythmique induite chez les patients asymptomatiques

Not yet recruiting
3
298
Europe
Bisoprolol, Nebivolol, Flécaïnide, Verapamil, Diltiazem, Amiodarone, Sotalol, PROPAFENONE, C01BC03
Assistance Publique - Hôpitaux de Paris, PHRC
Premature ventricular contractions (PVCs) Contractions ventriculaires prématurées (PVC), Premature ventricular contractions (PVCs) Contractions ventriculaires prématurées (PVC), Diseases [C] - Cardiovascular Diseases [C14]
 
 
NCT02624765: Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)

Completed
3
105
Europe, Canada, US, RoW
Digoxin (monotherapy), Sotalol (monotherapy), Flecainide (monotherapy), Digoxin (dual therapy), Sotalol (dual therapy), Flecainide (dual therapy)
Edgar Jaeggi, Canadian Institutes of Health Research (CIHR)
Fetal Atrial Flutter Without Hydrops, Fetal Supraventricular Tachycardia Without Hydrops, Fetal Supraventricular Tachycardia With Hydrops
03/24
03/24
NCT05939076: First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation

Not yet recruiting
3
220
Europe
Pulmonary vein isolation, dronedarone - Multaq™ OR flecainide - Tambocor™ OR propafenone - Rytmonorm™ OR sotalol - Sotacor™
Region Örebro County, The Swedish Research Council, Erling-Persson Stiftelse, Swedish Heart Lung Foundation, Uppsala University
Atrial Fibrillation, Persistent
12/27
12/28
EARLY-AF, NCT02825979: Early Aggressive Invasive Intervention for Atrial Fibrillation

Active, not recruiting
N/A
303
Canada
Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy, sotalol, flecainide, propafenone, dronedarone
Jason Andrade, Ottawa Heart Institute Research Corporation, Medtronic, Baylis Medical Company
Atrial Fibrillation
09/22
11/22
DOFEGEN, NCT02439658: Genetics of QT Prolongation With Antiarrhythmics

Recruiting
N/A
1000
US
Dofetilide and/or sotalol, Tikosyn
Massachusetts General Hospital, Mayo Clinic, The Cleveland Clinic, University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)
Long QT Syndrome, Drug Toxicity
12/22
04/23
ECTOPIA, NCT03845010 / 2018-001518-13: Elimination of VPB With Ablation Versus Anti-arrhythmic Drug Treatment

Completed
N/A
22
Europe
Sotalol, Flecainide and verapamil, Catheter ablation
Maatschap Cardiologie Zwolle, Isala Zwolle
Ventricular Premature Beats
01/23
01/23
Cryo-InitialAF, NCT04942834: Using Cryoballoon Ablation as Initial Treatment for Persistent Atrial Fibrillation

Recruiting
N/A
286
RoW
Antiarrhythmic drug including Propafenone, Sotalol, Dronedarone and Amiodarone, cryoballoon ablation
Ruijin Hospital
Atrial Fibrillation, Persistent, Arrhythmias, Cardiac
07/25
01/26
PEAKS, NCT05247320: Prospective Evaluation Analysis and Kinetics Registry

Completed
N/A
167
US
Sotalol Injection
University of Utah, AltaThera Pharmaceuticals, LLC
Atrial Arrhythmia
08/23
08/23
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting
N/A
484
Europe, Canada, US, RoW
FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific Corporation
Persistent Atrial Fibrillation
02/26
12/27
EDearly AF, NCT06322017: Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation

Recruiting
N/A
294
Europe
Rhythm control by Pulmonary Vein Isolation (PVI) procedure, Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin)
Nantes University Hospital
Atrial Fibrillation
04/28
04/28
NCT06669299: Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies

Not yet recruiting
N/A
51
Europe
Re-Do ventricular tachycardia ablation, Antiarrhythmic Drug Therapy (amiodarone, sotalol, or mexiletine)
IRCCS Ospedale San Raffaele
Ventricular Tachycardia (VT)
12/27
12/27
ChiCTR2400088934: The prevention effect of Sotalol for post-operative atrial fibrillation after coronary artery bypass grafting: a randomized contrlled trial

Recruiting
N/A
340
 
Sotalol ; Metoprolol
Fuwai Hospital, Chinese Academy of Medical Sciences; Fuwai Hospital, Chinese Academy of Medical Sciences, National High Level Hospital Clinical Research Funding
coronary artery disease
 
 
dronedarone / Generic mfg.
2010-019442-87: Dronedarone in pacemaker patients with paroxysmal atrial fibrillation

Ongoing
4
50
Europe
Dronedarone - Multaq, Multaq, Multaq
East Sussex NHS Trust
Paroxysmal atrial fibrillation
 
 
EDORA, NCT04704050: Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence

Terminated
4
22
US
dronedarone 400 mg Oral Tablet, Multaq®, Placebo
Tulane University School of Medicine, University of Washington, Marrek, INC, Sanofi, Preventice, Mckesson
Atrial Fibrillation, Atrial Fibrillation Recurrent
12/22
12/22
ChiCTR2200062928: Effects of oral dronedarone hydrochloride tablets on NOACs concentrations in patients with paroxysmal or persistent atrial fibrillation: a randomized, controlled, single-center clinical study

Not yet recruiting
4
75
 
Amiodarone 200mg qd combined with dabigatran 110mg bid for 1 month ;Dronedarone 400mg bid plus dabigatran 110mg bid for 1 month ;Dabigatran 150mg bid for 1 month ;Amiodarone 200mg qd combined with rivaroxaban 15mg qd for 1 month ;Dronedarone 400mg bid combined with rivaroxaban 15mg qd for 1 month ;Rivaroxaban 20mg qd for 1 month
The First Hospital of China Medical University; The First Hospital of China Medical University, The CSPC Ouyi Pharmaceutical Co., Ltd
Atrial fibrillation
 
 
ChiCTR2100052758: A multicenter, randomized controlled clinical study of oral dronedarone hydrochloride tablets after catheter ablation in patients with persistent atrial fibrillation to reduce the first recurrence of atrial fibrillation

Recruiting
4
200
 
Dronedarone Hydrochloride Tablets ;Amiodarone
Shenzhen Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences; Shenzhen Hospital, Fuwai Hospital, Chinese Academy of Medical Sciences, The CSPC Ouyi Pharmaceutical Co., Ltd.
Atrial fibrillation
 
 
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation

Completed
4
339
US
Dronedarone, Multaq
American Heart Association, Duke Clinical Research Institute, Sanofi
Atrial Fibrillation
01/24
06/24
ChiCTR2200066977: Comparison of the effectiveness and safety of dronedarone and amiodarone for preventing atrial fibrillation recurrence after catheter ablation: an open label study

Not yet recruiting
4
280
 
Dronedarone ;Amidarone
The First Affiliated Hospital, Zhejiang University School of Medicine; The First Affiliated Hospital, Zhejiang University School of Medicine, Shijiazhuang Pharmaceutical Group Ouyi Pharmaceutical Co., Ltd
Atrial Fibrillation
 
 
DORIS, NCT05655468: Effect of Prolonged Use of Dronedarone on Recurrence in Patients With Non-paroxysmal Atrial Fibrillation After Radiofrequency Ablation

Recruiting
4
268
RoW
Dronedarone, Placebo
Shanghai East Hospital
Atrial Fibrillation
04/25
11/25
ChiCTR2300069986: Effect of oral dronedarone hydrochloride tablets on rivaroxaban serum concentration in patients with paroxysmal and persistent atrial fibrillation：A randomized, controlled, single-center clinical study

Not yet recruiting
4
60
 
Dronedarone 400mg bid, Rivaroxaban 15mg qd, 1 month ;Rivaroxaban 15mg qd, 1 month
The Second Affiliated Hospital of the Military Medical University of the PLA Air Force; The Second Affiliated Hospital of the Military Medical University of the PLA Air Force, The CSPC Ouyi Pharmaceutical Co.，Ltd
Atrial Fibrillation
 
 
ChiCTR2500096575: Study on the effect of Shensong Yangxin capsule combined with dronedarone on maintaining sinus rhythm after radiofrequency ablation for persistent atrial fibrillation

Not yet recruiting
4
120
 
The total course of treatment for Shensong Yangxin Capsules 1.6g tid+Dronedarone 400mg bid orally was 3 months, and later changed to Shensong Yangxin Capsules 1.6g tid to maintain for 1 year.; Dronedarone 400mg bid for a total course of 3 months
Mianyang 404 Hospital; Mianyang 404 Hospital, raise independently
atrial fibrillation
 
 
ChiCTR2400086750: Safety and efficacy of dronedarone combined with sorafenib in the treatment of advanced hepatocellular carcinoma: a phase I/II exploratory study

Not yet recruiting
1/2
46
 
Dronedarone combined with sorafenib
The First Affiliated Hospital of Army Medical University, PLA; The First Affiliated Hospital of Army Medical University, PLA, Self-funded
hepatocellular carcinoma
 
 
DMT-PVC I, ChiCTR2200058438: Dronedarone versus metoprolol in the treatment of idiopathic RVOT premature ventricular complexes: a multicenter, parallel, open label, randomized controlled trial-

Not yet recruiting
N/A
110
 
Dronedarone 400mg bid (morning and evening with meals), for 3 months ;Metoprolol, 25mg bid, for 3 months
The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital); The First Affiliated Hospital with Nanjing Medical University (Jiangsu Province Hospital), The CSPC Ouyi Pharmaceutical Co., Ltd
Premature ventricular complexes
 
 
Sotylize (sotalol oral solution) / Azurity Pharma
No trials found

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