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29 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Vasaloc (low-dose danazol) / Ampio
NCT03312400: Low-Dose Danazol for the Treatment of Telomere Related Diseases

Recruiting
2
40
US
Danazol
National Heart, Lung, and Blood Institute (NHLBI)
Telomere Disease
04/26
10/27
danazol oral / Generic mfg.
ChiCTR-TRC-12002424: Clinical study on therapeutic efficacy and mechanism of all-trance-retinoid acid in refractory immune thrombocytopenia patients

Completed
4
80
 
All-trance retinoid acid + Danazol ;Danazol
Peking University People's Hospital, Peking University Institute of Hematology; Level of the institution:, Beijing Municipal Science and technology Commission
immune thrombocytopenia
 
 
ChiCTR1900025219: A prospective, open-label, multicenter clinical trail for Ruxolitinib combined with Prednisone, Thalidomide and Danazole in adult patients wiht myelofibrosis

Not yet recruiting
4
80
 
Ruxolitinib combined with Prednisone, Thalidomide and Danazol
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences; Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Institute of Hematology and Blood Diseases Hospital,Chinese Academy of Medical Sciences
myelofibrosis
 
 
ChiCTR2000041485: Efficacy of Danazol after no response to cyclosporin in transfusion independent aplastic anemia: a prospective study

Recruiting
4
228
 
Cyclosporine combined with danazol ;Cyclosporine
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, self-raised
transfusion independent aplastic anemia
 
 
ChiCTR2400090244: Efficacy and Safety of Danazol Suppository in the Treatment of Endometriosis-Associated Pain:A Clinical Study

Not yet recruiting
4
200
 
Use danazol suppositories regularly
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences; Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, The company funded
Endometriosis
 
 
MOMENTUM, NCT04173494 / 2019-000583-18: A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants

Calendar Jan 2024 - Dec 2024: Regulatory approval in EU (based on MOMENTUM trial) for myelofibrosis
Hourglass Jan 2023 - Jun 2023 : Approval in US for myelofibrosis (based on MOMENTUM trial)
Jun 2023 - Jun 2023: Anticipated FDA action date for NDA in myelofibrosis based on MOMENTUM trial
Checkmark New data from MOMENTUM trial in myelofibrosis at ASH 2022
Dec 2022 - Dec 2022: New data from MOMENTUM trial in myelofibrosis at ASH 2022
More
Completed
3
195
Europe, Canada, US, RoW
Momelotinib, MMB, GS-0387, CYT387, Placebo to match danazol, Danazol, Danocrine, Placebo to match momelotinib
Sierra Oncology LLC - a GSK company
Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
12/21
12/22
2018-004400-19: Study of the effects of telomerase reactivation with Danazol on ovarian function. A Pilot Study. Estudio de los efectos de la reactivación de la telomerasa con Danazol en la función ovárica. Estudio piloto.

Not yet recruiting
3
45
Europe
Capsule, DANATROL
IVIRMA MADRID, FINOX AG
low ovarian reserve Baja respuesta ovárica, Premature ovarian aging Envejecimiento del ovario, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13]
 
 
PACIFICA, NCT03165734 / 2017-001772-28: A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

Calendar May 2026 - Sep 2026: Data from PACIFICA trial for myelofibrosis
Recruiting
3
399
Europe, Canada, US, RoW
Pacritinib, Physician's Choice medications, corticosteroids, hydroxyurea, danazol, low-dose ruxolitinib
Swedish Orphan Biovitrum, Sobi, Inc., PSI CRO
Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
06/25
12/25
NCT05697471: Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis

Recruiting
3
120
RoW
Dienogest, Danazol
Far Eastern Memorial Hospital
Endometriosis
12/25
12/25
NCT04324060: A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia

Active, not recruiting
2/3
75
RoW
Danazol + rhTPO (recombinant human thrombopoietin injection), Danazol + sodium chloride
Peking Union Medical College Hospital
Low/Intermediate Risk-1 MDS
03/22
12/22
ACTRN12620001363976p: The TELO-SCOPE Study: Attenuating Telomere Attrition with Danazol. Is there Scope to Dramatically Improve Health Outcomes for Adults and Children with Pulmonary Fibrosis?

Not yet recruiting
2
50
 
The University of Queensland, Australian Government Department of Health, Medical Research Future Fund
Pulmonary fibrosis associated with age adjusted telomere length less than the 10th centile.
 
 
ACTRN12620001363976: The TELO-SCOPE Study: Attenuating Telomere Attrition with Danazol. Is there Scope to Dramatically Improve Health Outcomes for Adults and Children with Pulmonary Fibrosis?

Recruiting
2
50
 
The University of Queensland, Australian Government Department of Health, Medical Research Future Fund
Pulmonary fibrosis associated with age adjusted telomere length less than the 10th centile.
 
 
NCT04481282: The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
40
RoW
Terbutaline, Bricanyl Brethine, Danazol, Danocrine, Cleregil, Danol
Peking University People's Hospital
Immune Thrombocytopenia
03/21
07/21
NCT05353673: The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
120
RoW
Sitagliptin, JANUVIA, Danazol, Danocrine
Peking University People's Hospital
Immune Thrombocytopenia, Blood Coagulation Disorders, Thrombocytopenia, Physiological Effects of Drugs
12/22
02/23
NCT05471050: The Combination of Tacrolimus and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
120
RoW
TAC, Danazol
Peking University People's Hospital
Immune Thrombocytopenia
03/23
06/23
NCT05281068: The Combination of Iguratimod and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
120
RoW
Iguratimod, Iremod, Danazol
Peking University People's Hospital, Beijing Hospital, China-Japan Friendship Hospital, Beijing Friendship Hospital, The First Affiliated Hospital of Zhengzhou University, First Affiliated Hospital of Chongqing Medical University, Shanxi Bethune hospital, Shanxi, China
ITP, Immune Thrombocytopenia
09/23
12/23
NCT05494307: The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia

Not yet recruiting
2
228
NA
Terbutaline, Danazol
Peking University People's Hospital
Immune Thrombocytopenia
09/23
02/24
NCT06176911: The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
124
RoW
Teriflunomide, AUBAGIO, Danazol
Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital
Immune Thrombocytopenia
12/24
07/25
NCT05852847: Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
216
RoW
Baricitinib 2 MG [Olumiant], Olumiant, Danazol
Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital
Immune Thrombocytopenia
11/24
05/25
TELO-SCOPE, NCT04638517: The Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

Recruiting
2
50
RoW
Danazol, Placebo
The University of Queensland
Pulmonary Fibrosis, Telomere Shortening, Telomere Disease, Dyskeratosis Congenita
12/24
06/25
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
NCT04873102: Danazol for Treatment of Cytopenias in Patients With Cirrhosis

Recruiting
2
10
US
Danazol Pill, Danocrine
University of Southern California
Cirrhosis, Liver, Cytopenia
11/25
11/25
NCT03460808: The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Not yet recruiting
1/2
200
RoW
atorvastatin, Acetylcysteine, Danazol, Danocrine, Cleregil, Danol
Peking University People's Hospital
Immune Thrombocytopenia
01/20
01/23
ANDROTELO, NCT03710356 / 2018-001686-17: Evaluating Efficacy and Safety of Danazol in Severe Hematologic or Pulmonary Disease Related to Telomeropathy

Not yet recruiting
1/2
40
NA
Danazol 200 MG
Assistance Publique - Hôpitaux de Paris
Telomere Shortening, Telomere Length, Mean Leukocyte
10/21
10/22
PRETELL, NCT04807309: PREvention of TELomere-related Complications After Lung Transplant

Withdrawn
1/2
30
NA
Danazol Pill, Placebo
Brigham and Women's Hospital
Short Telomere Length, Lung Transplant
11/21
01/22
ChiCTR1800020309: Autophagy mechanism of ovarian EMs cells with intervention of Luo's prescription for endometriosis based on PI3K/Akt/mTOR signaling pathway: an in vitro study

Not yet recruiting
N/A
200
 
None ;Luo 's prescription for endometriosis ;Luo 's prescription for endometriosis ;Luo 's prescription for endometriosis ;Danazol ;Danazol ;Danazol ;Temsirolimus ;Temsirolimus ;Temsirolimus
The First Affiliated Hospital of Guangzhou University of Chinese Medicine; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Traditional Chinese Medicine Bureau Of Guangdong Province
Endometriosis
 
 
ChiCTR1900027553: Clinical therapies for patients in subtypes of non-severe aplastic anemia

Not yet recruiting
N/A
490
 
Cyclosporine ;Cyclosporine ;Cyclosporine+Danazol ;CSA+TPO+G-CSF
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, Tianjin Major Disease Prevention and Control Science and Technology Project
non-severe aplastic anemia
 
 
ChiCTR1800016177: Withdraw by the investigator Efficacy and safety of danazol combined with low-dose glucocorticoids in the treatment of refractory/recurrent primary immune thrombocytopenia: a multicenter, single arm, prospective and open clinical study

Suspended
N/A
30
 
danazol combined with low-dose glucocorticoids
Second Affiliated Hospital of Dalian Medical University; Second affiliated hospital of Dalian medical university, Research funding
Immune thrombocytopenic purpura
 
 
ethinyl estradiol/ferrous fumarate/norethindrone / Generic mfg.
NCT04899778: Do Oral Contraceptives Protect Against ACL Injuries in Female Athletes

Recruiting
4
100
US
Oral Contraceptive Pill, norethindrn a-e estradiol-iron, Birth Control, norethindrn a-e estradiol-iron, Blisovi 24 Fe 1 mg-20 mcg
Cedars-Sinai Medical Center
Ligament Injury
09/24
12/24
Lyta 28 (levonorgestrel/ethinylestradiol/ferrous fumarate) / Incepta Pharma
No trials found
vaginal danazol (VML-0501) / Viramal
No trials found

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