| RNS60 / Revalesio |
2016-002382-62: The effects of RNS60 on ALS biomarkers L'effetto del farmaco RNS60 sui biomarcatori della SLA |
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| Ongoing | 2 | 142 | Europe | RNS60, RNS60, Solution for infusion, Nebuliser solution | IRCCS- ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI, Associazione ALSA, Revalesio Corporation, Associazione "Get out" ONLUS | Amyotrophic Lateral Sclerosis Sclerosi Laterale Amiotrofica, Motor Neuron Disease Malattia del neurone motorio, Diseases [C] - Nervous System Diseases [C10] | | | | |
RESCUE, NCT04693715: Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy |
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| Completed | 2 | 82 | US | RNS60, Placebo | Revalesio Corporation | Stroke, Ischemic | 11/23 | 11/23 | | |
NCT02988297: Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis |
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| Not yet recruiting | 2 | 140 | NA | RNS60, Placebo | Revalesio Corporation | Amyotrophic Lateral Sclerosis | 11/27 | 11/27 | | |
| Amitiza (lubiprostone) / Takeda, Mallinckrodt |
NCT04985669: Study of Comparative Effectiveness of Prucalopride and Lubiprostone in Constipation Predominant Irritable Bowel Syndrome |
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| Recruiting | 4 | 140 | RoW | Prucalopride 2mg, calopride | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Patient Satisfaction | 02/22 | 03/22 | | |
ChiCTR2400088155: Evaluating lubiprostone for effective in colonoscopic bowel preparation |
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| Not yet recruiting | 4 | 244 | | Use of rupiprostenone before bowel preparation; Use of rupiprostenone before bowel preparation; control group 1 ; control group 12 | The Affiliated People’s Hospital of Ningbo University; The Affiliated People’s Hospital of Ningbo University, self-finance | Bowel Preparation | | | | |
ChiCTR2400090921: A Randomized Controlled Study of the Efficacy and Safety of a Bowel Preparation Regimen of 1L Polyethylene Glycol Combined with Lubiprostone Versus 2L Polyethylene Glycol |
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| Not yet recruiting | 4 | 284 | | 1L Polyethylene Glycol (PEG) + Lubiprostone; 2L Polyethylene Glycol (PEG) | The First Affiliated Hospital Of Guangzhou Medical University; The First Affiliated Hospital Of Guangzhou Medical University, Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd | Bowel preparation protocol before colonoscopy | | | | |
ChiCTR2400090127: Efficacy and Safety of Lubiprostone Compared to Lactulose in Elderly Patients with Chronic Constipation: A Randomized, Controlled, Open-Label, Multicenter Clinical Study |
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| Not yet recruiting | 4 | 190 | | Subjects will take Lubiprostone capsules orally for 4 consecutive weeks, 24 μg per capsule, 1 capsule per dose, twice daily; Subjects will take lactulose solution orally for 4 consecutive weeks, starting with an initial dose of 30 mL per day. The maintenance dose will be 10-25 mL per day, administered orally, for a total duration of 4 weeks. | Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School; Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Corporate Sponsorship | Chronic constipation | | | | |
ChiCTR1800015360: The efficacy and safety of Lubiprostone capsule in the treatment of functional constipation: a randomized, double-blind, multi-center, placebo-parallel-controlled Confirmatory clinical trial |
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| Not yet recruiting | 3 | 260 | | lubiprostone capsules ;Placebo capsules | The First Affiliated Hospital of Sun Yat-sen University; Nanjing ChiaTai TianQing Pharmaceuticals LP, self-raised | functional constipation | | | | |
NCT05768334: Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease |
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| Completed | 3 | 116 | RoW | Lubiprostone 24Mcg Oral twice daily | Helwan University | NAFLD | 02/23 | 02/23 | | |
NCT06543979: Anorectal Manometery in Pediatric Chronic Refractory Constipation |
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| Recruiting | 1/2 | 60 | RoW | lubiprostone , single arm, lubicont, biofeed back sessions, botox injection | Ain Shams University | Chronic Constipation | 09/25 | 10/25 | | |
| Recruiting | N/A | 3000 | RoW | No Intervention | Jeil Pharmaceutical Co., Ltd. | Constipation | 05/24 | 11/24 | | |
NCT03720613: Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain |
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| Recruiting | N/A | 34532 | US | Naldemedine, Symproic®, Lubiprostone, Amitiza®, Naloxegol, Movantik® | BioDelivery Sciences International, HealthCore, Inc. | Opioid-induced Constipation | 11/30 | 11/30 | | |
| rufinamide / Generic mfg. |
NCT03778424: An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303 |
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| Available | N/A | | Europe | Rufinamide | Eisai Inc. | Lennox Gastaut Syndrome | | | | |
| Recruiting | N/A | 1000 | Europe | Valproic acid, carbamazepine, phenobarbital, phenytoin, levetiracetam, lamotrigine, topiramate, oxcarbazepine, stiripentol, clobazam, brivaracétam, felbamate, lacosamide, rufinamide, gabapentine, pregabaline, sultiame, tiagabine, vigabatrine, mesuximide, primidone, perampanel, ethosuximide, zonisamide, cannabidiol, genetic polymorphisms | Assistance Publique - Hôpitaux de Paris | Epilepsy | 06/26 | 06/26 | | |
| piracetam / Generic mfg. |
ChiCTR2000034474: Clinical observation of piracetam injection in the treatment of cerebral infarction patients |
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| Not yet recruiting | 4 | 360 | | piracetam injection | Zhujiang Hospital of Southern Medical University; Zhujiang Hospital of Southern Medical University, sponsor | Cerebral infarction | | | | |
ChiCTR2000040466: A randomized, blinding, parallel controlled, multicenter clinical trial of compound procine cerebroside and ganglioside injection in the treatment of craniocerebral injury |
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| Recruiting | 4 | 900 | | compound procine cerebroside and ganglioside injection; Piracetam Injection | Tianjin Medical University General Hospital; Tianjin Medical University General Hospital, Jilin Tiancheng Pharmaceutical Co., Ltd | craniocerebral injury | | | | |
NCT05918341: Subtherapeutic Dose of Piracetam as a Therapy Adherence Marker |
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| Not yet recruiting | 4 | 10 | NA | Piracetam | The Netherlands Cancer Institute | Drug Adherence Marker | 09/23 | 09/23 | | |
| Not yet recruiting | 4 | 60 | NA | Piracetam, no other interventions, Placebo | Ain Shams University, King Salman International university | Diabetic Peripheral Neuropathy | 08/25 | 08/25 | | |
2005-005460-80: A single center, randomized, open-label, comparative study to assess efficacy and safety of piracetam 4.8g/d administered for 6 months as adjuvant to standard vestibular rehabilitation (VR) therapy utilizing Cooksey Cawthorne exercises to adults suffering from moderate to severe vertigo of peripheral origin lasting for at least 3 months. |
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| Ongoing | 2 | 50 | Europe | Nootrop, | N/A | moderate to severe vertigo of peripheral origin | | | | |
ChiCTR2400083497: A study on the impact of EEG biofeedback therapy on cognitive function in patients with non dementia vascular cognitive impairment |
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| Recruiting | 1 | 76 | | On the basis of routine treatment and nursing, combined with EEG biofeedback adjuvant therapy, once a day, 30 minutes each time, 5 times a week, a total of 10 times (intervention for 4 weeks).; Routine treatment includes: controlling blood pressure, regulating blood sugar, regulating lipid metabolism, nourishing nerves, and improving circulation, while administering drugs that improve cognitive function such as ibuprofen soft capsules, piracetam capsules, and donepezil hydrochloride Routine care: such as admission guidance, dietary care, medication guidance, primary rehabilitation gymnastics guidance, psychological care, and discharge rehabilitation guidance. | Affiliated Hospital of North Sichuan Medical College; Affiliated Hospital of North Sichuan Medical College, Hospital provide their own supplies | vascular cognitive impairment no dementia | | | | |
NCT06689644: Effect of a Plant Based Nootropic on Perceptual Decision Making. |
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| Completed | N/A | 37 | Europe | Nootropics (ginkgo biloba, nicergoline, piracetam, or others), Placebo, Perceptual decision-making performance, Electroencephalography | University of Leeds | Cognitive Enhancement | 03/24 | 06/24 | | |
| SR419 / Shanghai SIMR Biotech |
NCT05357677: To Evaluate the Efficacy and Safety of SR419 in Patients With Postherpetic Neuralgia (PHN) |
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| Completed | 2 | 83 | RoW | SR419 | Shanghai SIMR Biotechnology Co., Ltd. | Postherpetic Neuralgia | 01/23 | 01/23 | | |
| M201-A / AETAS Pharma |
NCT04609059: First-in-Patient Study for Sing le Dose of M201-A Hydrochloride Injection in Japanese Patients With Paroxysmal Atrial Fibrillation |
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| Recruiting | 2 | 42 | Japan | M201-A Injection, Placebo | Kitasato University, Aetas Pharma Co., Ltd. | Paroxysmal Atrial Fibrillation | 10/19 | 12/20 | | |
| SR750 / Shanghai SIMR Biotech |
NCT06571448: Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia |
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| Not yet recruiting | 2 | 162 | NA | SR750 tablet, Placebo | Shanghai SIMR Biotechnology Co., Ltd. | Trigeminal Neuralgia | 10/25 | 11/25 | | |
NCT05083468: The Safety, Tolerability, and Pharmacokinetics (PK) of SR750 in Healthy Volunteers |
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| Completed | 1 | 83 | RoW | SR750 tablet, matching placebo | SIMR (Australia) Biotech Pty Ltd. | Healthy Volunteers | 10/22 | 10/22 | | |
NCT05753033: The Pharmacokinetics (PK), Safety, Tolerability of SR750 in Healthy Volunteers |
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| Completed | 1 | 56 | RoW | SR750 tablet, Placebo | Shanghai SIMR Biotechnology Co., Ltd. | Healthy | 09/23 | 09/23 | | |
| Undisclosed epilepsy therapeutic / Shanghai SIMR Biotech |
| No trials found |
