Ongoing

2

20

Europe

Carbenoxolone, Carbenoxolone, Carbenoxolone

University Hospitals Birmingham NHS Trust

Impared glucose tolerance

 

 

Completed

4

78

 

salt water ;Ondansetron ;Granisetron ;metoclopramide+oxytocin ;Hemabate ;Hemabate+oxytocin ;methergine ;methergine+oxytocin ;Dexmedetomidine ;Dexmedetomidine+oxytocin ;oxytocin ;tropisetron ;tropisetron

Department of Anesthesiology, West China Second University Hospital, Sichuan University; Level of the institution：, Self-financing

isolated—uterine smooth muscle in pregnant women

 

 

Not yet recruiting

4

69

 

1.20 minutes befor the operation, intravenous inject with 10mg dexamethasone, 100mg FlurbiprofenAxetil. 2. preincision, inject with 8ml 0.5%levobupivacaine in subcutaneous and transversusabdominis. 3. afterlaparotomy, inject with 8ml 0.5%levobupivacaine in transversusabdominis. 4. beforsutureperitoneum, inject with 8ml 0.5% levobupivacaine in subcutaneous and transversusabdominis. 5. Celecoxib, 200mg per day, 3 days, take orally. ;After open colectomy, give the patient a patient-controlled analgesia pump. apatient-controlled analgesia pump contain 200ug sufentanil, 5mg Dezocine, 3mg Tropisetron, 100ml physiological saline. ;After laparoscopy, give the patient a patient-controlled analgesia pump. apatient-controlled analgesia pump contain 200ug sufentanil, 5mg Dezocine, 3mg Tropisetron, 100ml physiological saline.

Department of Digestive Surgery, Xijing Hospital of Digestive Diseases, the Fourth Military Medical University; Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, Nil

colon carcinoma

 

 

Recruiting

4

200

 

no tropisetron ;give tropisetron

Shiyan Taihe Hospital, Hubei University of Medicine; Shiyan Taihe Hospital, Hubei University of Medicine, National Natural Science Foundation of China (NSFC, Grant No. 81270414)

Postoperative the transition from acute pain to chronic pain after cesarean section

 

 

Not yet recruiting

4

40

 

Tropisetron combined with Risperidone ;Placebo combined with Risperidone

Beijing An'ding Hospital, Capital Medical University; Beijing An'ding Hospital, Capital Medical University, Beijing Municipal Administration of Hospitals'Youth Programme ' Talent cultivation in Beijing Anding Hospital (subject nova)

schizophrenia

 

 

Completed

4

180

 

5mg tropisetron ;1ug/kg nalmefene ;2ug/kg nalmefene

Sichuan Academy of Medical Sciences · Sichuan Provincial People's Hospital; Sichuan Academy of Medical Sciences · Sichuan Provincial People's Hospital, Self-supporting

Postoperative pain of pulmonary nodules

 

 

Not yet recruiting

4

300

 

Fentanyl 1mg + esketamine 50mg + tropisetron 10mg) ;Fentanyl 1mg + Tropisetron 10mg

Panzhihua Central Hospital; Panzhihua Central Hospital, Panzhihua City Guiding Science and Technology Department

postpartum depression, PPD

 

 

Not yet recruiting

4

100

 

Sufentanil 2 μg/kg + ketochromate tromethamine 90 mg + S-ketamine 50 mg + tropisetron 30 mg + 0.9% sodium chloride solution, the volume is 120 ml ;Sufentanil 2 μg/kg +ketochromate tromethamine 90 mg +tropisetron 30 mg + 0.9% sodium chloride solution, the volume is 120 ml

Peking University Cancer Hospital & Institute; Peking University Cancer Hospital & Institute, N/A

s-ketamine related neurometabolic molecular pathway

 

 

Recruiting

4

136

 

5 mg dexamethasone, 5 mg tropisetron, ;5 mg tropisetron

Changhai Hospital, Navy Military Medical University, Shanghai; Changhai Hospital, Navy Military Medical University, Shanghai, Self-raised

primary liver cancer

 

 

Completed

4

200

RoW

tropisetron, metoclopramide, dexamethasone, normal saline

The Second Affiliated Hospital of Chongqing Medical University

Nausea and Vomiting

10/23

11/23

Completed

4

480

RoW

Glycopyrronium in Combination With Tropisetron, Normal Saline in Combination With Tropisetron

The Second Affiliated Hospital of Chongqing Medical University, Chongqing General Hospital, Chongqing Medical University, The People's Hospital of DAZU ，Chongqing, The People's Hospital of Chongqing Kaizhou District, Fuling Hospital affiliated to Chongqing University, Qianjiang Central Hospital of Chongqing, Stomatological Hospital of Chongqing Medical University, People's Hospital of Changshou Chongqing, The Ninth People's Hospital of Chongqing, The First People's Hospital Of Chongqing Liang Jiang New Area, People's Hospital of Xiushan County, Wushan County People's Hospital, Three Gorges Hospital of Chongqing University, First Affiliated Hospital of Chongqing Medical University, Department of Anesthesiology, Daping Hospital, Institute of Surgery Research, the Army Medical University, The People's Hospital of Nanchuan, Chongqing Traditional Chinese Medicine Hospital, People's Hospital of Shapingba District， Chongqing, Chongqing Liangping District People's Hospital, Chongqing Jiangbei Hospital of Traditional Chinese Medicine, People's Hospital of Chongqing Hechuan

Postoperative Nausea and Vomiting

06/23

06/23

Not yet recruiting

4

110

 

nomal saline 5ml iv ;Tropisetron 5mg iv injection

Xiangyang Central Hospital; Xiangyang Central Hospital, Hospital

Patients with brachial plexus anesthesia

 

 

Not yet recruiting

4

90

 

Postoperative analgesia pump use: 2 μg/kg + 10 mg of tropisetron + 0.9% saline to 100 mL; Postoperative analgesia pump use: 2 μg/kg + dexketoprofen tromethamine 300 mg + tropisetron 10 mg + 0.9% saline to 100 mL

Hangzhou First People's Hospital; Hangzhou First People's Hospital, Self-funded

Postoperative pain

 

 

Completed

3

116

RoW

Fosaprepitant, shanqi, tropisetron, luoting, Dexamethasone, xiluoan

Shantou University Medical College

Cervical Cancer, Nasopharyngeal Cancer, Chemotherapy-induced Nausea and Vomiting, Radiation-Induced Nausea and Vomiting, Antiemetic

07/23

08/23

Recruiting

2

68

 

Cheek acupuncture combined with tropisetron; Tropisetron

First Affiliated Hospital of China Medical University; First Affiliated Hospital of China Medical University, Department of Anesthesiology,First Affiliated Hospital of China Medical University

Postoperative nausea and vomiting(PONV)

 

 

Recruiting

1

130

 

Tropisetron ;Tropisetron and propofol

People's Hospital of Three Gorges University; People's Hospital of Three Gorges University, self-funded

nausea and vomit

 

 

Not yet recruiting

N/A

120

 

Day 1 palonosetron+dexamethasone+aprepitant, Day 2~4 dexamethasone+aprepitant ;Day 1 tropisetron+dexamethasone+aprepitant, Day 2~4 dexamethasone+aprepitant ;Day 1 palonosetron+dexamethasone, Day 2~4 dexamethasone ;Day 1 palonosetron+dexamethasone, Day 2~4 dexamethasone+metoclopramide

Guangzhou General Hospitol of Guangzhou Military Command PLA; Guangzhou General Hospitol of Guangzhou Military Command PLA, Self-funded

Chemotherapy-induced nausea andvomiting

 

 

Completed

N/A

173

 

Acupuncture + Drugs ;Acupuncture + Normal saline ;Drugs+False acupuncture ;Normal saline+False acupuncture

Cangzhou Central Hospital; Cangzhou Central Hospital, Providing by department

Nausea and vomiting

 

 

Not yet recruiting

N/A

288

 

Phase I: ginger and tangerine warm-stomach cream tropisetronon; Phase II: blank ;Phase I: blank, Phase II: ginger and tangerine warm-stomach cream tropisetronon

The First College of Clinical Medicine, Guangzhou University of Chinese Medicine; The First College of Clinical Medicine, Guangzhou University of Chinese Medicine, self-financed

colorectal cancer

 

 

Recruiting

N/A

600

 

navoban 5mg intravenous injection and dexamethasone 5mg intravenous infusion ;navoban 5mg intravenous injection and dexamethasone 5mg acupoint injection ;navoban 5mg intravenous injection and saline 1ml acupoint injection ;navoban 5mg intravenous injection and simple acupoint stimulation ;navoban 5mg intravenous injection and dexamethasone 5mg 2cm injection beside acupoint

Shaanxi Province Tumor Hospital; Shaanxi Province Tumor Hospital, own expense

nausea and vomiting after surgery

 

 

Recruiting

N/A

50

 

1 hour before induction of anesthesia, oral celecoxib capsules 200 mg, pregabalin capsules 150 mg；Before the end of the operation, use ropivacaine injection 20ml: 150mg for local infiltration anesthesia at the operating area or screw entry site；After the patient was awake from anesthesia, he was intravenously infus ;After the patient is awake from anesthesia, a patient-controlled analgesia pump is placed intravenously, prepared with 100ug sufentanil citrate, 10mg tropisetron hydrochloride injection, and 20mg dezocine injection (loading volume 2ml + continuous dose 2ml/h + self-controlled analgesia The pump dose is 0.5ml/time, the lock

Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine; Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine, The equipment and materials needed for the research will be provided by the hospital of traditional Chinese medicine of xinjiang uygur autonomous region

Lumbar degenerative disease

 

 

Recruiting

N/A

102

 

ultrasound-guided transversus abdominis plane block (0.375% ropivacaine 20ml on each side） combined with PCIA（butorphanol 3.5ug/kg/h ，flurbiprofen axetil 83 ug/kg/h+Tropisetron mesylate13.33mg) ;sufentanil 150ug, tropisetron mesylate 13.33mg ;morphine 8mg, ropivacaine 135mg

Guangdong Second Provincial General Hospital; Guangdong Second Provincial General Hospital, Youth Fund Projects of Guangdong Second Provincial General Hospital

Cesarean section

 

 

Completed

N/A

90

 

0.5% lidocaine 5mL planetary ganglion block after general anesthesia induction+1mL saline intravenous injection after surgery; After induction of general anesthesia, 0.5% lidocaine 5mL planetary ganglion block+intravenous injection of 5mg (1mL) of bitropisetron; Intravenous injection of 5mg (1mL) of Sabidosetron

Gynecological patients who require laparoscopic surgery

 

 

Recruiting

N/A

300

 

Fentanyl 15ug/kg+ tolisetron 10mg ;Butorphanol 0.15mg/kg+ Tropisetron 10mg ;Fentanyl 7.5ug/kg+ butorphanol 0.075mg/kg+ tolisetron 10mg

The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, Special Fund for Clinical Exploration of Static Analgesia in Guizhou, Yunnan Town

Gastrointestinal tract and thoracic tumors

 

 

Not yet recruiting

N/A

90

 

 

 

Not yet recruiting

N/A

84

 

After admission, relevant contraindications were excluded and PCIA analgesia was used. The formula was 2ug/kg sufentanil+10mg tropisetron, diluted with physiological saline to 100ml, with a background dose of 2ml/h set, and no patient-controlled analgesic dose set.; Perform ultrasound guided PENG block, using local anesthetic: 15ml of bupivacaine liposome+ 5ml of 0.9% NS, with a total amount of 20ml. After observing for 0.5 hours to confirm no adverse reactions, PCIA analgesic pump was used. The drug formula, except for the absence of sufentanil, was set with the same drugs and parameters as Group B.

Fujian provincial hospital; Fujian provincial hospital, None

Preoperative analgesia for hip fracture

 

 

Not yet recruiting

N/A

120

 

Postoperative analgesic formula in the experimental group (S group): sufentanil 2ug/kg + esketamine 0.72mg/kg + tropisetron 6mg; Postoperative analgesic formula in the control group (C group): sufentanil 2ug/kg + tropisetron 6mg

Affiliated Hospital of Xuzhou Medical University; Affiliated Hospital of Xuzhou Medical University, raise independently

sleep disturbance

 

 

Not yet recruiting

N/A

126

 

Add 2ug/kg sufentanil+tropisetron 20mg+0.5mg/kg of Esketamine in the electronic analgesia pump, the total amount is 200ml, the load is 12.5ml, and the maintenance amount is 2ml/h. PCIA2ml, lock-in time of 15 minutes, and the entire process of psychological counseling provided by psychologists to the patient.; Add 2ug/kg sufentanil+tropisetron 20mg to the electronic analgesic pump, with a total volume of 200ml, a loading capacity of 12.5ml, and a maintenance capacity of 2ml/h. PCIA2ml, lock-in time of 15 minutes, and the entire process of psychological counseling provided by psychologists to the patient.

Beijing Anzhen Hospital affiliated to Beijing Capital Medical University; Beijing Anzhen Hospital affiliated to Capital Medical University, Self-financed

Postoperative depression symptoms after cardiac valve surgery under extracorporeal circulation

 

 

Not yet recruiting

N/A

564

 

After admission to the laboratory, routine anesthesia monitoring, general anesthesia induced propofol 1.5mg/kg, sufentanil 0.3-0.6ug/kg, cis-atracurium besylate 0.15mg/kg, followed by intraoperative continuous intravenous infusion of propofol 4-12mg/kg/h + remifentanil 0.1-1.0ug/kg/h, intermittent intravenous bolus injection of cis-atracurium besylate to maintain good muscle relaxation, continued until the end of the operation; After the end of the operation, a disposable electronic pump intravenous self-controlled analgesia (PCIA, sufentanil 0.03ug/kg/h + tropisetron 10 mg) was started with a total volume of 100 ml, and continuous infusion was started at a rate of 2 mL/hr for 48 hours.; After admission, routine anesthesia monitoring, general anesthesia induced propofol 1.5mg/kg, sufentanil 0.3ug/kg, esketamine 0.25mg/kg, cis-atracurium besylate 0.15mg/kg, and then intraoperative continuous intravenous infusion of 0.25-0.5mg/kg/h of esketamine + propofol 4-12mg/kg/h + remifentanil 0.1-1.0ug/kg/h, intermittent intravenous bolus injection of cis-atracurium besylate to maintain a good muscle relaxation state, Continue until the end of the procedure; After the end of the operation, a disposable electronic pump was started with intravenous self-controlled analgesia (PCIA, sufentanil 0.03 ug/kg/h + esketamine 0.015 mg/kg/h + tropisetron 10 mg) with a total volume of 100 ml, and continuous infusion was started at a rate of 2 mL/hr for 48 hours.; After entering the room, routine anesthesia monitoring was induced by general anesthesia with propofol 1.5 mg/kg, esketamine 0.5 mg/kg, cis-atracurium besylate 0.15 mg/kg, followed by intraoperative continuous intravenous infusion of 0.5-1.0 mg/kg/h of esketamine + propofol 4-12 mg/kg/h, and intermittent intravenous bolus injection of cis-atracurium besylate to maintain good muscle relaxation until the end of the operation. After the end of the operation, a disposable electronic pump was started with intravenous self-controlled analgesia (PCIA, esketamine 0.03 mg/kg/h + tropisetron 10 mg) with a total volume of 100 ml, and continuous infusion was started at a rate of 2 mL/hr for 48 hours.

Xuzhou Central Hospital; Xuzhou Central Hospital, Xuzhou Central Hospital

postoperative delirium