Completed

4

880

 

Acarbose: titrated from 50mg qd to 100mg tid, taken for 12 months. Anothore oral Antidiabetic agent can be added after 6 months therapy ;Metformin: titrated from 500mg qd to 1500mg qd, taken for 12 months. Anothore oral Antidiabetic agent can be added after 6 months therapy.

China-Japan Friendship Hospital; Chinese Diabetes Society, Bayer Healthcare Company Ltd.

Newly diagnosed type 2 diabetes

 

 

Completed

4

100

 

Acarbose+conventional hypoglycemic therapy ;conventional hypoglycemic therapy

The Second Affiliated Hospital of Dalian Medical University; The Second Affiliated Hospital of Dalian Medical University, Part from a investigator initiative funds for Bayer Health and Pharmaceuticals, Beijing, China. Part from Liaoning Provincial funds for Natural Science, 20062160

Diabetes Mellitus

 

 

Completed

4

50

 

acarbose compared to placebo

Peking University People's Hospital; Level of the institution：, Bayer Healthcare

Diabetes

 

 

Completed

4

4100

 

acarbose

The General Hospital of the People's Liberation Army (PLAGH); The General Hospital of the People's Liberation Army (PLAGH), Bayer healthcare

Hypertension and ischemic heart disease

 

 

Ongoing

4

50

Europe

Glucobay 50 / 100, 9835.01.00,

Medizinische Klinik B, Herzzentrum Ludwigshafen

1. To study the effect of Acarbose treatment on endothelial function as a potential mechanism for the beneficial effects of better postprandial glycemic control in patients with impaired glucose tolerance or newly diagnosed diabetes mellitus

 

 

Not yet recruiting

4

50

 

Placebo ;acarbose

China-Japan Friendship Hospital; Bureau of Health Care for Senior Officials, Health Care for Senior Officials Foundation

postprandial hypotension

 

 

Recruiting

4

648

 

saxagliptin combination therapy with metformin ;saxagliptin combination therapy with acarbose ;saxagliptin combination therapy with gliclazide MR

China-Japan Friendship Hospital; AstraZeneca Pharmaceutical Co. Ltd, AstraZeneca Pharmaceutical Co. Ltd

Type 2 diabetes mellitus

 

 

Recruiting

4

160

 

saxagliptin ;acarbose

Tianjin Medical University Metabolic Diseases Hospital; Tianjin Medical University Metabolic Diseases Hospital, Tianjin Medical University

Diabetic nephropathy

 

 

Recruiting

4

90

 

dapaglifozin ;acarbose

The Second Hospital of Changzhou, affiliated to Nanjing Medical University; Level of the institution：, Patients self-care after signing informed consent

type 2 diabetes

 

 

Recruiting

4

128

 

Dapagliflozin(Anda don) 10mg once after breakfast increase Metfomin 500mg twice after breakfast and dinner,if glucose controls poor,metformin can be added to 1000mg twice after breakfast and dinner. ;Acarbose (Bai Tang) 50 mg three times at the same time of three meals increase Metfomin 500mg twice after breakfast and dinner,if glucose controls poor,metformin can be added to 1000mg twice after breakfast and dinner and Acarbose can be added to 100mg three times at the same time of

Zhujiang Hospital, Southern Medical University; Zhujiang Hospital, Southern Medical University, Self-financing

Type 2 diabetes

 

 

Not yet recruiting

4

150

 

Acarbose ;Sitagliptin

Beijing Hospital; Beijing Hospital, BAYER Company

Type 2 diabetes

 

 

Recruiting

4

432

 

Insulin / metformin + acarbose chewable tablets ;Insulin / metformin

The First Affiliated Hospital of Zhengzhou University; Hangzhou Sino-US East China Pharmaceutical Co., Ltd., Hangzhou Sino-US East China Pharmaceutical Co., Ltd.

type 2 diabetes

 

 

Not yet recruiting

4

600

 

basic medication + Dapagliflozin ;basic medication + Acarbose

The Affiliated Hospital of Qingdao University; The Affiliated Hospital of Qingdao University, Self-raising

type 2 diabetes

 

 

Completed

4

87

 

After 7-10 days of intensive insulin pump treatment, the combination of insulin glargine, metformin hydrochloride and liraglutide was given; After 7-10 days of intensive insulin pump therapy, metformin hydrochloride, daglipzin and acarbose were given combined therapy

Guangrao County People's Hospital of Dongying city; Department of Endocrinology, Guangrao County People's Hospital of Dongying city, Department of Endocrinology, Guangrao County People,s Hospital of Dongying city

Type 2 Diabetes

 

 

Recruiting

3

50

RoW

Metformin plus pioglitazone, Acarbose

Nanjing First Hospital, Nanjing Medical University

Type 2 Diabetes, Blood Glucose Fluctuation

05/23

05/23

Not yet recruiting

3

1780

Europe

Tablet, Solution for injection

ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), DGOS

Pregnant women with Gestational Diabetes Mellitus (GDM) Diabète gestationnel, Pregnant women with Gestational diabetes mellitus (GDM) Diabète Gestationnel chez la femme enceinte, Diseases [C] - Nutritional and Metabolic Diseases [C18]

 

 

Not yet recruiting

2

48

 

Sanye Tablets + Acarbose Simulation Agent ;Sanye Tablets Simulation Agent + Acarbose Simulation Agent ;Acarbose +Sanye Tablets Simulation Agent

Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine; Tianjin University of Traditional Chinese Medicine, The central government funding for 4.7441 million yuan, according to the regulations of the contract that project tasks, to local investment 5 million yuan, enterprises (units) self-raised 7.5 million

Type 2 Diabetes Mellitus and Hyperlipidemia

 

 

Active, not recruiting

2

320

Europe

EMP16-120/40, MR orlistat 120 mg, Conventional orlistat 120 mg,, Xenical, EMP16-60/20, Placebo

Empros Pharma AB, CTC Clinical Trial Consultants AB

Overweight or Obesity

11/23

03/24

Completed

1

20

 

Three leaves tablet vs acarbose

the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine; The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, National special projects for major new drugs created by Ministry of Science and Technology

diabetes mellitus

 

 

Completed

1

300

 

Diet and exercise interventions ;Diet, exercise and acarbose interventions ;Diet, exercise and Probucol interventions

West China Hospital, Sichuan University; West China Hospital, Sichuan University, Science and Technology Bureau of Sichuan Province, China; Bayer; Shandong Qilu Pharmaceutical Co., Ltd.; Medtronic, Inc.

Diabetes

 

 

Recruiting

1

16

 

different dose of acarbose

The Third Xiangya Hospital of Central South University; The Third Xiangya Hospital of Central South University, NA

NA

 

 

Not yet recruiting

1

60

 

Sucrose-Sucrose+TEST 100mg-Sucrose-Sucrose+CONTROL 100mg ;Sucrose-Sucrose+CONTROL 100mg-Sucrose-Sucrose+TEST 100mg

West China Hospital, Sichuan University; West China Hospital, Sichuan University, From Sponsor

None, Healthy adults

 

 

Recruiting

1

600

RoW

Metformin, gliclazide modified release tablets, acarbose, Lantus, Novomix30

Third Affiliated Hospital, Sun Yat-Sen University

Diabetic Retinopathy

07/23

07/25

Completed

N/A

30

 

Acarbose+routine diet guidence for diabetes patients ;Acarbose+whole grains, traditional Chinese medicinal foods and prebiotics diet

Shanghai Jiao Tong University; Shanghai Jiao Tong University, National Nature Science Foundation

Type 2 Diabetes

 

 

Completed

N/A

46

 

Saxagliptin ;acarbose

Jiangsu Jiankang Vocational College; JIANGSU JIANKANG VOCATIONAL COLLEGE, college level

diabetes

 

 

Not yet recruiting

N/A

120

 

Sancailianmei particle ;acarbose

Teaching Hospital of Chengdu University of Traditional Chinese Medicine; Chengdu university of traditional Chinese medicine, Special project funds

type 2 Diabetes Mellitus

 

 

Recruiting

N/A

50

 

Sitagliptin ;acarbose

South Hospital of Fujian Provincial Hospital; Fujian Medical University, Fujian medical university sailing fund

diabetic peripheral neuropathy

 

 

Recruiting

N/A

240

 

Dietary fiber ;Acarbose+Dietary fiber ;Semaglutide ;Dulaglutide

Shanghai First People's Hospital; Shanghai First People's Hospital, Shanghai Jiaotong University Medical-Engineering Cross Research Fund

polycystic ovary syndrome (PCOS)

 

 

Not yet recruiting

3

118

NA

Voglibose + Metformin, Glibenclamide + Metformin

University of Zambia, University Teaching Hospital, Lusaka, Zambia

Diabetes Mellitus Type 2 Without Complication

12/23

01/24

Recruiting

3

30

RoW

Miglustat, Zavesca

Tehran University of Medical Sciences, Mashhad University of Medical Sciences, Kashan University of Medical Sciences

GM2 Gangliosidosis, Supportive Care

12/24

12/24

Ongoing

2

24

Europe

ZAVESCA, ZAVESCA, ZAVESCA

HOSPICES CIVILS DE LYON

Mucopolysaccharidose de type III

 

 

Not yet recruiting

2

10

Europe

Miglustat Gen.Orph 100 mg, capsule rigide, [Miglustat Gen.Orph 100 mg, capsule rigide], Capsule, hard, MIGLUSTAT GEN.ORPH - 100 MG - CAPSULA, RIGIDA - USO ORALE - BLISTER (OPA/ALLU/PVC) - 84 CAPSULE

IRCCS Fondazione Stella Maris, IRCCS Fondazione Stella Maris, Tom Wahlig Stiftung Foundation

Spastic paraparesis type 11 (SPG11), caused by mutations in spatacsin protein, is characterized by the association of peripheral neuropathy, parkinsonism, ataxia, cognitive impairment, hypotrophy of the corpus callosum and retinal degeneration. The disease progresses with degeneration of motor and cognitive functions up to total dependence on caregivers. At the moment there are no therapies capable of modifying its natural history and progression. Paraparesi spastica di tipo 11 (SPG11) è la forma di paraparesi spastica autosomica recessiva più frequente dovuta a mutazioni della proteina spatacsina. E' caratterizzata dall’ associazione di neuropatia periferica, parkinsonismo, atassia, deficit cognitivo, e degenerazione retinica. La malattia progredisce con degenerazione delle funzioni motorie e cognitive fino alla totale dipendenza dai caregivers. Al momento non vi sono terapie capaci di modificarne la storia naturale e la progressione., SPG11 is a rare, uncurable neurodegenerative disease characterized by weak and stiff legs, ataxia, dementia with progressive loss of autonomy. La SPG11 è una malattia genetica del cervello e dei nervi caratterizzata da debolezza e rigidità degli arti, parkinsonismo, disequilibrio, e perdita di autonomia ed è senza cura., Diseases [C] - Nervous System Diseases [C10]

 

 

Active, not recruiting

1/2

6

US

Miglustat 100Mg Oral Capsule

Beyond Batten Disease Foundation, Theranexus

Batten Disease

05/24

08/24

Not yet recruiting

2

156

Europe

EMP16-02 120/40, EMP16-02 150/50, Capsule

Empros Pharma AB, Empros Pharma AB

Obesity Fetma, Obesity Fetma, Body processes [G] - Metabolic Phenomena [G03]

 

 

Recruiting

1

20

Europe

Xenical® vs EMP 22, Part I, EMP 22 vs Xenical®, EMP 16 vs Xenical®, Part II

Empros Pharma AB, CTC Clinical Trial Consultants AB

Overweight or Obesity

12/24

12/24