α2 adrenergic receptor antag Trials

160 Trials

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Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

idazoxan (RX 781094) / Houston Pharma

NCT05727189: A Study of Idazoxan in Healthy Participants

Recruiting

150

RoW

TR-01-XRR (1), R-Idazoxan HCL Extended Release (medium release rate) Tablet, TR-01-XRR (2), R-Idazoxan HCL Extended Release (faster release rate) Tablet, TR-01-XRR (3), R-Idazoxan HCL Extended Release (slower release rate) Tablet, TR-01-XRS, S-Idazoxan Extended Release Tablet, TR-01-XR, Racemic Idazoxan HCL Extended Release Tablet, TR-01-IR, Idazoxan HCL Immediate Release Tablet, Placebo, Matching Placebo Tablet

Terran Biosciences Australia Pty Ltd

Healthy

03/24

Validive (clonidine MBT) / Monopar Therap

2021-000999-11: Study comparing the efficacy and safety of a clonidine tablet that sticks to the gum to a placebo tablet to prevent severe inflammation of the mouth caused by radiation treatment in patients with cancer in the middle of the throat Estudio que compara la eficacia y la seguridad de una tableta de clonidina que se pega a la encía versus tableta de placebo para prevenir una inflamación severa de la boca causada por el tratamiento de radiación en pacientes con cáncer en el medio de la garganta

Not yet recruiting

2/3

260

Europe

Validive (Clonidine HCl mucoadhesive buccal tablet (MBT)), Muco-adhesive buccal tablet

Monopar Therapeutics Inc., Monopar Therapeutics Inc.

Chemoradiotherapy (CRT)-induced severe oral mucositis (SOM) in patients with oropharyngeal cancer (OPC) Mucositis oral severa (MOS) inducida por quimioradioterapia (QRT) en pacientes con cáncer orofaríngeo (COF), Severe inflammation of the mouth caused by radiation treatment in patients with cancer in the middle of the throat Inflamación severa de la boca causada por el tratamiento de radiación en pacientes con cáncer en el medio de la garganta, Body processes [G] - Digestive System and Oral Physiological Phenomena [G10]

VOICE, NCT04648020 / 2021-000999-11: Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer.

Terminated

190

Europe, US

Clonidine HCl Mucoadhesive Buccal Tablet, Validive®, Placebo Mucoadhesive Buccal Tablet

Monopar Therapeutics, Monopar Therapeutics Inc.

Chemoradiotherapy-Induced Severe Oral Mucositis

05/23

maprotiline / Generic mfg.

2013-004881-33: Multicentre trial in to investigate the usage of antidepressant and antipsychotics (with / without approval) in patients at the age of children and adolescents Groß an gelegte, einfache offene klinische Studie mit mehreren teilnehmenden Prüfzentren zur Anwendung von Antidepressiva und Neuroleptika (mit /ohne Zulassung)

Ongoing

1000

Europe

Tablet, Abilify, Zyprexa, Leponex, Seroquel, Risperdal, Zeldox, Melneurin, Dipiperon, Saroten, Cipramil, Anafranil, Aponal, Cymbalta, Cipralex, Fluctin, Fevarin, Tofranil, Ludiomil, Remergil, Nortrilen, Paroxat, Zoloft, Stangyl, Trevilor

Universitätsklinikum Würzburg, Kompetenznetz TDM-KJP e.V., BfArM

therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, Psychiatry and Psychology [F] - Mental Disorders [F03]

Teluron (terguride) / Pfizer, ErgoNex

2015-002586-39: Terguride Plus Symptomatic Therapy in Patients with Diffuse Cutaneous Systemic Sclerosis

Ongoing

148

Europe

Terguride, /, Tablet, METOCLOPRAMIDE ACCORD - 10 MG COMPRESSE 28 COMPRESSE IN BLISTER PVC/PVDC/AL

medac GmbH, MEDAC GMBH, medac GmbH

Diffuse cutaneous systemic sclerosis (dcSSc), systemic sclerosis, Diseases [C] - Immune System Diseases [C20]

2009-017869-27: A dual-center, open-label Proof of Concept study to evaluate the efficacy of Terguride for the treatment of fibrosis in patients with systemic sclerosis.

Ongoing

Europe

Terguride, PR1,

University Hospital Zurich

Diffuse scleroderma

paliperidone extended release / Generic mfg.

ChiCTR-IPR-16009208: The safety of Paliperidone Extended-Release Tablets and Olanzapine in treating patients with schizophrenia

Recruiting

120

Paliperidone Extended-Release Tablets ;Olanzapine

The Seventh People's Hospital of Shaoxing City; the seventh people’s hospital of Shaoxing City, the seventh people’s hospital of Shaoxing City

schizophrenia

NCT04478838: "Extended" (Alternate Day) Antipsychotic Dosing

Recruiting

120

Canada

Risperidone, Risperdal, Olanzapine, Zyprexa, Apo-Olanzapine, Sandoz-Olanzapine, Invega Paliperidone

Centre for Addiction and Mental Health

Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents

09/27

09/28

2006-005734-20: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Flexible Dose Paliperidone ER in the Treatment of Subjects with Schizoaffective Disorder

Ongoing

Europe

Paliperidone ER, R076477,

Janssen L.P.

Schizoaffective disorder

ChiCTR-TRC-12002273: Effects of paliperidone extended-release tablets (paliperidone ER) and olanzapine on metabolic profile, insulin resistance and beta-cell function in schizophrenic patients: a randomized 12-week study

Completed

N/A

paliperidone extended-release ;olanzapine

First Affiliated Hospital, College of Medicine, Zhejiang University; Level of the institution：, Key Medical Disciplines Funds in Zhejiang Province

Schizophrenia

ChiCTR-TRC-14004854: A randomized, controlled, multi-center clinical trial to study the treatment resistant schizophrenia (TRS) in Zhejiang province

Completed

N/A

200

Paliperidone Extended-Release Tablets ;Olanzapine

First Affiliated Hospital, Zhejiang University School of Medicine; None, self-financing

Schizophrenia

ChiCTR-TRC-14004452: The efficacy and safety of Paliperidone Extended-Release Tablets combined with sodium valproate in Bipolar disorder manic episode

Recruiting

N/A

200

PANSS ;Paliperidone Extended-Release Tablets combined with placebo ;Paliperidone Extended-Release Tablets combined with sodium valproate

First Affiliated Hospital, College of Medicine, Zhejiang University; First Affiliated Hospital, College of Medicine, Zhejiang University, National Natural Science Foundation (81301158)

Bipolar disorder

quetiapine / Generic mfg.

2007-004513-33: Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression

Ongoing

300

Europe

Dispersible tablet, Tablet, Lamictal, TillVal Folysra (Folic acid)

University of Oxford

Bipolar depression

ChiCTR2200061843: A 24-Week, Randomized, Open-Label, Haloperidol-Control Study to Evaluate the Efficacy of Quetiapine in Improving Social Cognitive Function of Patients with Schizophrenia

Completed

treatment with quetiapine ;treatment with haliperidol

Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Xi’An Janssen Pharmaceutical Ltd.

Schizophrenia

ChiCTR-TNRC-10001112: The study on clinical and biological characters of bipolar depression and the treatment scheme optimizing

Completed

640

Lithium, Sodium valproate, Lamotrigine, MECT, Sertraline, Citalopram, Escitalopram, venlafaxine, Quetiapine, Olanzapine, Risperidone, sulpiride

Guangzhou Scientific and Technological Bureau, Guangzhou Board of Health; Guangzhou first people's hospital, The Tackling Key Problems of Guangzhou Scientific and Technological Project

bipolar depressive disorder

ChiCTR-TRC-10000934: Pharmacogenomic study of schizophrenia

Completed

3000

Perphenazine 16-64 mg/d (N=250) or Haloperidol 6-20 mg/d (N=250) ;Risperidone 2-6mg/d ;Olanzapine 5-20 mg/d ;Quetiapine 400-750mg/d ;Aripiperazole 10~30 mg/d ;Ziprasidone 80-160 mg/d

The Sixth Hospital / Institute of Mental Health, Peking University; The Ministry of Science and Technology, The National High Technology Research and Development Program of China (863 program)

Schizophrenia

ChiCTR-IPR-16009475: The research of chronic insomnia clinical evaluation and optimization of treatment

Completed

100

alprazolam ;Zolpidem ;Trazodone ;Quetiapine

Shanghai Mental Health Center; Shanghai Mental Health Center, Shanghai science and technology committee

chronic insomnia

2004-003826-92: \"A Randomized, Parallel Group, Open Trial Examining the Safety, Efficacy and Tolerability of Fast Titration, 800mg/day by day 4, of Quetiapine Fumarate Compared to Standard Titration, 400mg/day by day 4, in the Treatment of Bipolar 1 Manic Episode.\"

Ongoing

150

Europe

Fumarato de quetiapina (Seroquel), Seroquel 25 mg comprimidos recubiertos con película Seroquel 100 mg comprimidos recubiertos con película Seroquel 200 mg comprimidos recubiertos con película, Seroquel 25 mg comprimidos recubiertos con película Seroquel 100 mg comprimidos recubiertos con película Seroquel 200 mg comprimidos recubiertos con película

AstraZeneca Farmacéutica Spain, S.A.

Tratamiento del Episodio Maníaco Bipolar Tipo I

2004-005078-22: Quetiapin: Zur Sicherheit, Verträglichkeit und zum Einfluss auf kognitive Funktionen bei Patienten/innen mit einer schizophrenen Psychose Quetiapine: safety and influence on cognitive functions in patients with schizophrenia: a single-trial event-related potential analysis

Ongoing

Europe

Seroquel®, 47291.00.00, 47291.01.00, 47291.02.00, Seroquel®, Seroquel®

Medical School of Hannover

Patients with schizophrenia, who are not in an acute state of psychosis at enrolment (PANSS score < 80) and who do not show criteria of moderate depression, but may show depression-like symptoms corresponding to negative symptoms of schizophrenia (MADRS score ≤XXX). ICD classification code : F 20.0, 20.1, 20.2, 20.3, 20.5, 20.6

2004-002608-13: Pragmatic Randomised Control Trial of Quetiapine for psychosis in Parkinson’s Disease

Ongoing

Europe

Seroquel, Seroquel, Seroquel

King’s College London & King’s College Hospital

Parkinson\'s Disease with psychosis

2005-005072-32: Is it possible to modify the course of manic relapse? A pilot study of the effectiveness of quetiapine in preventing the development of manic episodes in Bipolar Disorder.

Ongoing

Europe

Quetiapine, Seroquel 100mg, Seroquel 150mg, Seroquel 200mg, Seroquel 300mg, Seroquel 100mg, Seroquel 150mg, Seroquel 200mg, Seroquel 300mg

Kings College London (IOP) / South London and Maudsley NHS Trust (Co-sponsorship)

Bipolar Disorder

2006-001317-15: BALANCE 2: Bipolar disorder:Antidepressant/Lamotrigine/ANtipsychotic Comparative Evaluation

Ongoing

630

Europe

Selective Serotonin Reuptake Inhibitors, SSRI, Quetiapine, Lamotrigine, Quetiapine, Lamotrigine

University of Oxford

Bipolar depression.

2006-002342-11: Multicenter study of neurotransmitters and neuropeptides in schizophrenia: A multidisciplinary study of biological, pharmacokinetic, receptor occupancy and clinical relationships in patients suffering from schizophrenia treated with quetiapine (Seroquel®).

Ongoing

Europe

Seroquel 25, Seroquel 100, Seroquel 300, Seroquel 25, Seroquel 100, Seroquel 300, Seroquel 25, Seroquel 100, Seroquel 300

Klinikum Fulda gAG

Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.

2007-000579-40: Effects of atypical versus typical neuroleptics on motivation, hedonia, and social cognition in patients with schizophrenia – an fMRI study

Ongoing

Europe

Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal

Charité Universitätsmedizin Berlin

Schizophrenia

2007-004528-19: Electrophysiological measurement of anterior cingulate cortex (ACC) function in schizophrenic patients treated with Seroquel® or Fluanxol®

Ongoing

Europe

Seroquel (Quetiapine), Fluanxol (Flupentixol), Seroquel, Fluanxol, Seroquel, Fluanxol

University of Wuerzburg

schizophrenia (295.10, 295.20, 295.30, 295.90 according to Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV)

2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD

Ongoing

300

Europe

Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary)

King\'s College London, North Essex Partnership NHS Foundation Trust

Alzheimer\'s disease

2013-003460-31: The effect of low doses of mirtazapine and quetiapine on sleep and daytime functioning.

Ongoing

Europe

mirtazapine, quetiapine, n/a,

GGZ-Drenthe, GGZ-Drenthe

Insomnia

2016-001637-27: Lithium versus Quetiapine in Treatment Resistant Depression.

Ongoing

276

Europe

Lithium carbonate, Quetiapine, Lithium citrate, Tablet, Syrup

South London and Maudsley NHS Foundation Trust, King's College London, National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme

Treatment resistant major depressive disorder (single episode or recurrent). Treatment resistant depression, defined as failure to respond to two or more adequate doses of antidepressant in the current episode, Treatment resistant depression: where the person with depression has not responded adequately to two or more antidepressants given in the current episode of depression., Psychiatry and Psychology [F] - Mental Disorders [F03]

2017-002406-12: HAMLETT. Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment. A study comparing continuation versus discontinuation/dose reduction of antipsychotic medication in patients remitted after a first episode of psychosis HAMLETT. Handling Antipsychotic Medication: Lange termijn evaluatie van specifiek toegepaste medicatie. Vergelijking tussen het doorgaan met antipsychotische medicatie bij patiënten die hersteld zijn van eerste psychotische episode en vroegtijdig afbouwen/stoppen.

Not yet recruiting

512

Europe

RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE, CID5073, CID135398745, CID5002, CID60795, CID3559, CID5355, CID115237, CID16362, CID213046, CID135398737, CID2159, CID5467, CID60149, CID667467, CIS5311507, Tablet, RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE

University Medical Center Groningen, ZonMw

HAMLETT compares regular treatment guidelines for patients in remission after a first episode of psychosis, namely continuation with antipsychotic medication for at least one year, with early dose reduction/discontinuation. HAMLETT vergelijkt de reguliere behandeling van patiënten in remissie na een eerste psychotische episode zoals beschreven in de richtlijnen, namelijk het continueren van antipsychotica voor minstens 1 jaar, met het vroegtijdig afbouwen/stoppen met medicatie., HAMLETT compares continuation versus early discontinuation of antipsychotic medication in patients who have recovered from their first episode of psychosis. HAMLETT vergelijkt de reguliere behandeling van patiënten die hersteld zijn van een eerste psychose, namelijk minimaal 1 jaar antipsychotica gebruiken, met vroegtijdig afbouwen/stoppn met medicatie, Psychiatry and Psychology [F] - Mental Disorders [F03]

2017-004602-17: Digital Medicine System

Not yet recruiting

Europe

DM-Aripiprazole, DM-Olanzapine, DM- Quetiapine, DM-Risperidone, Tablet, Aripiprazole, Olanzapine, Quetiapine, Risperidone

Otsuka Pharmaceutical, Otsuka Pharmaceutical

Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03]

ChiCTR1800014755: Study on individualized optimal treatment for antipsychotic drugs

Recruiting

2000

Risperidone ;Olanzapine ;Aripiperazole ;Quetiapine

国家科技部; Peking University Sixth Hospital, The Ministry of Science and Technology

Schizophrenia

LQD, NCT03004521: Lithium Versus Quetiapine in Treatment Resistant Depression

Recruiting

276

Europe

Quetiapine, Lithium

King's College London, University of Oxford, Newcastle University, Oxford Health NHS Foundation Trust, Northumberland, Tyne and Wear NHS Foundation Trust, South London and Maudsley NHS Foundation Trust, Tees, Esk and Wear Valleys NHS Foundation Trust, Sussex Partnership NHS Foundation Trust, Avon and Wiltshire Mental Health Partnership NHS Trust

Depressive Disorder, Treatment-Resistant

04/21

08/21

NCT04446234: Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building

Not yet recruiting

350

RoW

Risperidone, Aripiprazole, Ziprasidone, Amisulpride, Quetiapine

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine

Schizophrenia

12/22

NCT04513314: Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium

Withdrawn

Valproate, Depakote, Valproic acid, Quetiapine, seroquel, Standard of Care, Hospital Protocol

University of Miami

Covid19, Hyperactive Delirium, Pneumonia, Viral

03/23

ChiCTR2100049426: A randomized and controlled study of ruracidone in the treatment of bipolar depression in adolescents and early adulthood

Not yet recruiting

treatment with lurasidone ;treatment with quetiapine

Beijing AnDing Hospital, Capital Medical University; Beijing AnDing Hospital, Capital Medical University, Beijing Hospital Authority

bipolar disorder

TraQ, NCT05085808: RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium

Not yet recruiting

Trazodone, Desyrel, Quetiapine, Seroquel, Placebo

University of Southern California

Delirium, Morality, Quality of Life, Psych, Treatment Side Effects

07/26

12/26

ChiCTR2200064086: The clinical efficacy of Quetiapine in the treatment of PD hallucinations and the mechanism of electrophysiology and brain imaging

Not yet recruiting

Quetiapine ;none ;none

Nanjing Brain Hospital; Nanjing Brain Hospital, crosswise tasks

Parkinson's disease with hallucinations

CAMELOT, NCT05590637: Comparing Antipsychotic Medications in LBD Over Time

Recruiting

Pimavanserin, Nuplazid, Quetiapine, Seroquel

The University of Texas Health Science Center at San Antonio, Alzheimer's Association

Parkinson's Disease Psychosis, Dementia With Lewy Bodies

08/25

02/26

NCT05741502: An Exploratory Analysis of Immune and Inflammatory Response Associated with Clozapine

Recruiting

Clozapine, Antipsychotics,Other (non-Clozapine), Including Olanzapine, Risperidone, Paliperidone, Quetiapine, Aripiprazole, Ziprasidone, Lurasidone, Cariprazine, and all Typical antipsychotics

Ohio State University

Treatment-resistant Schizophrenia

03/26

06/26

NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder

Not yet recruiting

Hydroxyzine, Atarax, Vistaril, Escitalopram Oxalate, citalopram, fluoxetine, fluvoxamine, paroxetine, paroxetine CR, sertraline, venlafaxine XR,, Alprazolam, clomipramine, clonazepam, diazepam, imipramine, lorazepam, mirtazapine, reboxetine, Bupropion SR, divalproex, duloxetine, gabapentin, levetiracetam, milnacipran, moclobemide, olanzapine, phenelzine, quetiapine, risperidone, tranylcypromine

Sultan Qaboos University

Panic Disorder

12/26

2005-003251-13: Quetiapine Augmentation In Treatment-Resistant Depression – An Open Pilot Study

Ongoing

Europe

Seroquel, Seroquel 25 mg, Seroquel 100 mg, Seroquel 150 mg, Seroquel 200 mg, Seroquel 300 mg, Seroquel 25 mg, Seroquel 100 mg, Seroquel 150 mg, Seroquel 200 mg, Seroquel 300 mg

AstraZeneca UK Ltd

Depression

2009-011253-40: Paroxetine or Quetiapine in Addition to Mood Stabilizers in Bipolar Depression

Ongoing

Europe

DAPAROX*28CPR RIV 20MG PVC/PE/, SEROQUEL*60CPR RIV 100MG, DAPAROX*28CPR RIV 20MG PVC/PE/, SEROQUEL*60CPR RIV 100MG

AZIENDA SANITARIA OSPEDALIERA \"S. GIOVANNI BATTISTA DI TORINO\"

Major Depressive Episode in Bipolar Disorder

2010-021142-21: ?Alteraciones del sueño en pacientes con depresión mayor resistente al tratamiento con inhibidores selectivos de la recaptación de serotonina: ensayo clínico, aleatorizado, abierto, de grupos paralelos sobre la eficacia de Quetiapina de liberación prolongada vs Sales de Litio?

Ongoing

Europe

SEROQUEL PROLONG 50 mg comprimidos de liberación prolongada, PLENUR comprimidos de liberación modificada, SEROQUEL PROLONG 50 mg comprimidos de liberación prolongada, PLENUR comprimidos de liberación modificada

Fundación Institut de Recerca de l\' Hospital de la Santa Creu i Sant Pau

Depresión mayor resistente a Inhibidores Selectivos de la Recaptación de serotonina,Código de clasificación de la CIE : F-33

2016-004117-27: CONTROLLED, DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL FOR PROPHILAXIS OF POSOPERATIVE DELIRIUM IN HIGH RISK SURGICAL PATIENTS WITH QUETIAPINE. ENSAYO CLÍNICO CONTROLADO, DOBLE CIEGO Y ALEATORIZADO PARA LA PROFILAXIS CON QUETIAPINA DEL DELIRIO POSTOPERATORIO EN PACIENTES QUIRÚRGICOS DE RIESGO

Not yet recruiting

350

Europe

Capsule, Quetiapina NORMON 25 mg comprimidos recubiertos con peícula EFG

IBSAL (Instituto de Investigación Biomédica de, IBSAL, GRUPO DE RECUPERACION MULTIMODAL ESPAÑOL

Postoperative delirium in high risk surgical patients. Delirio postoperatorio en pacientes quirúrgicos de alto riesgo., Postoperative delirium. Delirio postoperatorio., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

NCT05690698: Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium

Completed

100

RoW

Quatiapine, Haloperidol

Alexandria University, Suez Canal University, Gezira University

Hyperactive Delirium

07/23

NCT06482554: Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms.

Recruiting

Lumateperone 42 mg, Lumateperone, Risperidone 2 mg, olanzapine; quetiapine; ziprasidone; aripiprazole

Louisiana State University Health Sciences Center Shreveport

Apathy, Schizophrenia, Schizophrenia; Psychosis

12/26

NCT06333990: Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

Recruiting

146

Quetiapine Fumarate, Seroquel, TAU, Treatment As Usual

Foundation for Advancing Veterans' Health Research, The University of Texas Health Science Center at San Antonio, Biomedical Research Institute of New Mexico

Mild Traumatic Brain Injury

06/28

INTENSIFY BD, NCT05973786: The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Recruiting

418

Europe

Escitalopram, ATC code: N06AB10, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04

Dr. Inge Winter, Universität Münster

Bipolar Depression

06/26

INTENSIFY, NCT05603104: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure

Recruiting

1254

RoW

Clozapine, ATC code: N05AH02, Esketamine Nasal Product, ATC code: N06AB10, Escitalopram, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04, Second-line Antidepressants, Second-line Antipsychotics, Ketamine Hydrochloride, N01AX03, Esketamine hydrochloride, N015X14

Dr. Inge Winter, Universität Münster

Schizophrenia and Related Disorders, Major Depressive Disorder, Bipolar Depression

06/26

2020-006062-36: A Phase II/III, randomized, 4-week, placebo-controlled study, designed to determine the safety, tolerability, and efficacy of evenamide (NW-3509) in patients with chronic schizophrenia.

Ongoing

2/3

196

Europe, RoW

Evenamide, NW3509, Capsule, hard

Newron Pharmaceuticals S.p.A., NEWRON PHARMACEUTICALS SPA, Newron Pharmaceuticals S.p.A, Newron Pharmaceuticals S.p.A., Newron Pharmaceuticals S.p.A

Chronic schizophrenia, Chronic schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03]

2021-001333-38: Clinical trial to study the effect of an already authorized drug on other pathologies by administering it to people with a recent diagnosis of schizophrenia. Ensayo clínico para estudiar el efecto que tiene un fármaco ya autorizado en otras patologías administrándolo en personas con reciente diagnóstico de esquizofrenia.

Not yet recruiting

2/3

Europe

VORTIOXETINA, HALOPERIDOL, Pimozida, Olanzapina, Risperidona, Chlorpromazine, Thioridazine, Quetiapine, Ziprasidone, aripiprazole, N06AX26, N05AD01, NO5AG02, NO5A H03, NO5AX08, N05AA01, N05AC02, N05AH04, N05AE04, N05AX12, Tablet, Capsule, hard, BRINTELLIX

Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI), Consejería de salud

Early schizophrenia Esquizofrenia temprana, Newly evolving schizophrenia Esquizofrenia de reciente evolución, Psychiatry and Psychology [F] - Mental Disorders [F03]

MEL-QUE, NCT06062953: Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients with Psychiatric Disorders and Comorbid Insomnia

Recruiting

2/3

255

Europe

Melatonin, Quetiapine, Placebo

Lone Baandrup, Danish Center for Sleep Medicine, Region Capital Denmark, Copenhagen Trial Unit, Center for Clinical Intervention Research, Mental Health Services in the Capital Region, Denmark

Psychiatric Disorders, Insomnia

02/29

ACTRN12622001532796: A multicentre, cluster randomised, double cross over pragmatic clinical trial comparing the safety and efficacy of enteral olanzapine with quetiapine in critically ill patients with hyperactive delirium

Not yet recruiting

1200

Royal Melbourne Hospital, The Australian and New Zealand Intensive Care Foundation

critical illness, hyperactive delirium

ACTRN12624001075572: A single centre pilot randomised controlled trial of enteral Guanfacine vs Quetiapine for agitated delirium in patients in the intensive care unit

Recruiting

Austin Hospital, Austin Health

Agitated delirium

2006-004783-31: A Double-Blind, Randomised, Parallel-Group, Placebo-Controlled, MultiCentre, Phase IIa Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ascending Multiple Oral Doses of AZD3480 in Schizophrenic Patients on Stable Antipsychotic Monotherapy with quetiapine, risperidone or olanzapine

Ongoing

Europe

AZD3480,

AstraZeneca AB

Schizophrenia

NCT05793632: Quetiapine in Prevention of Delirium

Completed

RoW

Quetiapine

Ain Shams University

Delirium

04/23

QOSA, NCT05303935: Effects of Quetiapine on Sleep and Next Day Alertness in People With Obstructive Sleep Apnea

Completed

RoW

Quetiapine 50 MG, Seroquel, Placebo, Sugar pill

Flinders University

Sleep Apnea, Obstructive

04/23

NCT04521478 / 2019-004264-21: A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Completed

389

Europe, Canada, Japan, US, RoW

BI 1358894, Placebo, Quetiapine

Boehringer Ingelheim

Depressive Disorder, Major

01/24

02/24

NCT04280965: Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury

Completed

Quetiapine Fumarate, Seroquel, Standard of care meducations

The University of Texas Health Science Center at San Antonio, South Central MIRECC

Post Traumatic Stress Disorder

04/22

10/22

NCT04950868: The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Active, not recruiting

Canada

Quetiapine

Verinder Sharma

Postpartum Depression

06/25

NCT05402111: A Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subjects With Schizophrenia Taking SEP-363856 or and Prior Antipsychotic (PA) Standard

Completed

SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

09/23

NCT05542264: A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia

Completed

SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

02/24

NCT05240261: Sleep Disorders in Chronic Kidney Disease Patients

Not yet recruiting

Quetiapine

Assiut University

Chronic Kidney Diseases

05/24

12/24

NCT06546358: Quetiapine Versus Trazadone in Women With Postpartum Depression

Not yet recruiting

Canada

Trazodone, Teva-Trazadone, Quetiapine, Quetiapine Fumarate

Lawson Health Research Institute

Postpartum Depression

09/25

12/25

ChiCTR2100054147: Correlation between dopamine receptor gene polymorphism and clinical effect of bipolar depressive episode

Not yet recruiting

180

Lamotrigine ;Quetiapine ;Bupropion ;None

Jiaxing Kangci Hospital; Jiaxing Kangci Hospital, Provincial Health Commission, Jiaxing Kangci Hospital, self-funded

Bipolar depression

ChiCTR-TRC-14004814: A randomized controlled trial of repetitive transcranial magnetic stimulation combined with quetiapine in the first-episode bipolar II depressive episode

Completed

N/A

quetiapine+false TMS treatment ;quetaipine+rTMS high-frequency ;quetaipine+rTMS low-frequency

The First Affiliated Hospital, Zhejiang University; The First Affiliated Hospital, Zhejiang University, Scientific research expenses

Bipolar II depressive episode

ChiCTR-IPR-16008425: Efficacy of quetiapine in behavioral and psychological symptoms of Alzheimer's disease patients

Not yet recruiting

N/A

120

Quetiapine ;Memantine

Changning Mental Health Center; Changning Mental Health Center, Key program of the Changning Science and Technology Committee

Alzheimer's disease

ChiCTR-COC-17011401: A study of gut microbiota, immunology, Imageology in patients with bipolar disorder

Recruiting

N/A

200

quetiapine monotherapy

First Affiliated Hospital, Zhejiang University School of Medicine; First Affiliated Hospital, Zhejiang University School of Medicine, Provincial Natural Science Foundation

Bipolar disorder

NCT06200584: Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics

Completed

N/A

140

RoW

Risperidone, neuroleptics, Olanzapine, Quetiapine, Risperidone and Vitamin D and Vitamin E, vitamin, Olanzapine and Vitamin D and Vitamin E, Quetiapine and Vitamin D and Vitamin E

Dr Rabia Arshad

Antipsychotics and Neuroleptics Toxicity

06/21

NCT05098353: Seroquel ® in Patients With Bipolar Disorder in Remission With Signs of Impaired Impulse Control

Recruiting

N/A

RoW

Quetiapine, Quetiapine - impulsivity

Federal Stare Budgetary Scientific Institution, Mental Health Research Center, Kazan State Medical University, Federal State Budgetary Institution V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, Saint-Petersburg, Russia

Bipolar Affective Disorder

11/21

12/21

NCT04209166: A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical Features

Recruiting

N/A

780

RoW

SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/ Serotonin and Norepinephrine Reuptake Inhibitors), SSRIs/SNRIs+Mood Stabilizer, SSRIs/SNRIs+Quetiapine, Usual Treatment

Shanghai Mental Health Center, Air Force Military Medical University, China, Guangzhou Psychiatric Hospital, Dalian Seventh People's Hospital, Wuhan Union Hospital, China, Shanghai Jiao Tong University School of Medicine

Major Depressive Disorder

10/22

SWITCH, NCT04312503: Observational Study on the Effect of Switch to Lurasidone in Subjects With Schizophrenia"

Completed

N/A

Europe

Lurasidone, Latuda, aripiprazole, olanzapine, quetiapine or risperidone

Aziende Chimiche Riunite Angelini Francesco S.p.A

Schizophrenia

10/22

ChiCTR2200059660: Clinical study of single intravenous injection of esmketamine combined with an oral antidepressant in the treatment of depressive disorde

Not yet recruiting

N/A

Use 0.25mg/kg ESM ketamine injection and physiological test Dilute saline injection to 50ml and drip intravenously for 40 minutes; Quetiapine fumarate (SRI Kang) was used as a synergist at a dose of 25-400 mg per day

Beijing Chaoyang Hospital; Beijing Chaoyang Hospital, self-raised

Depression

NCT05801289: Quetiapine as Prophylaxis for Delirium in CABG

Recruiting

N/A

RoW

Quetiapine, Seroquel

Ain Shams University

Delirium

04/23

NCT05840861: Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders

Recruiting

N/A

RoW

Vortioxetine, Quetiapine

Central South University

Major Depressive Disorder, Bipolar Disorder

08/23

09/23

NCT05833399: Correlation of Genetic Variations With Clinical Response in Substance Use Disorder

Recruiting

N/A

200

RoW

Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone, Seroquel, Olapex, Remeron, Tegretol, Moodapex, Tryptizol, Neurazine and Apexidone.

Alexandria University

Substance Use Disorders, Substance Dependence

03/24

12/24

ChiCTR2400083720: Effect of value orientation on brain activation in depressive patients with psychotic symptoms

Recruiting

N/A

Sertraline and quetiapine plus value-oriented short-term psychotherapy; Sertraline and quetiapine

The Second Affiliated Hospital of Xinxiang Medical College; The Second Affiliated Hospital of Xinxiang Medical College, Henan Province key research and development project

depression with psychotic symptoms

ChiCTR2100054169: Early effects of rTMS on bipolar depression by the modulation of prefrontal-amygdala/striatal brain network

Not yet recruiting

N/A

120

Combination therapy with rTMS and quetiapine ;Combination therapy with sham stimulation and quetiapine

Shenzhen Kangning Hospital; Shenzhen Kangning Hospital, Shenzhen Kangning Hospital

Bipolar depression

NCT06581302: Magnetic Seizure Therapy for Psychotic Disorders

Not yet recruiting

N/A

RoW

Magnetic seizure therapy by Magnetic stimulator, Seizure therapy, Antipsychotic medications (such as olanzpine, risperidone, aripiprazole, quetiapine, amisulpride, etc), antipsychotics

Shanghai Jiao Tong University School of Medicine

Psychotic Disorders

12/25

PRHDTDCSTMDE, NCT05498441: Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode

Recruiting

N/A

120

RoW

High-Definition Transcranial Direct Current Stimulation (HD-tDCS), Antipsychotics, mood stabilizers, etc.

Jiangsu Province Nanjing Brain Hospital

Major Depressive Episode

12/24

ChiCTR2300075440: Researches on the clinical curative effect of Yin-enching and Heat-cleaning on the treatment of the prodromal phases of bipolar disorder

Not yet recruiting

N/A

Traditional Chinese medicine formula granules+Imitated tablets of quetiapine fumarate; Chinese herbal placebo+quetiapine fumarate tablets

Beijing Anding Hospital，Capital Medical University; Beijing Anding Hospital，Capital Medical University, Beijing Municipal Administration of Hospital Incubating Program

the prodromal phases of bipolar disorder

TQDelirium, NCT05307003: Trazodone vs. Quetiapine for the Treatment of ICU Delirium

Recruiting

N/A

Trazodone, Desyrel, Quetiapine, Seroquel

University of Southern California

Delirium, Delirium of Mixed Origin, Delirium, Sepsis Associated, Delirium in Old Age, Delirium Confusional State, Psych, Morality, Treatment Side Effects

08/25

12/25

NCT04728581: Improving Sleep After TKA Using Mirtazapine and Quetiapine

Not yet recruiting

N/A

165

Europe

Mirtazapine, Quetiapine, Placebo

St. Anna Ziekenhuis, Geldrop, Netherlands

Osteo Arthritis Knee, Insomnia

05/26

01/27

NCT03449472: Bariatric Surgery and Pharmacokinetics of Quetiapine

Recruiting

N/A

Europe

Quetiapine, Quetiapine fumarate

Norwegian University of Science and Technology, St. Olavs Hospital, Volvat Medisinsk Senter Stokkan, Namsos Hospital, Alesund Hospital

Obesity, Morbid

10/26

CLASS-BD, NCT05480150: Chinese Longitudinal and Systematic Study of Bioplar Disorder

Recruiting

N/A

10000

RoW

Escitalopram Oxalate Tablets, Lexapro, Quetiapine Fumarate Tablets, Seroquel, Lurasidone, Latuda

First Affiliated Hospital of Zhejiang University

Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic

12/26

ACTRN12616001227482: Thyroid tests in people who are taking quetiapine.

Recruiting

N/A

PathWest Laboratory Medicine, PathWest Laboratory Medicine

Mental health disorders, Schizophrenia, Bipolar disorder, Anxiety

ACTRN12616001242415: Thyroid tests in people who will be taking quetiapine.

Recruiting

N/A

PathWest Laboratory Medicine, PathWest Laboratory Medicine

Psychosis, treated with quetiapine, Mood disorders, treated with quetiapine, Agitation, treated with quetiapine

quetiapine extended-release / Generic mfg.

APQ-TRD, NCT04936126: Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression

Recruiting

150

RoW

Quetiapine, Amantadine, Pramipexole

All India Institute of Medical Sciences, Bhubaneswar, Indian Council of Medical Research

Treatment Resistant Depression

07/24

09/24

SMART-BD, NCT06433635: Sequential Multiple Assignment Randomized Trial for Bipolar Depression

Not yet recruiting

2726

Canada, US

Cariprazine, Vraylar, Aripiprazole/Escitalopram combination, Abilify/ Lexapro, Quetiapine, Seroquel, Lurasidone, Latuda

Massachusetts General Hospital, Patient-Centered Outcomes Research Institute

Bipolar I Disorder, Depression

02/30

C-SAPP, NCT04373317: Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Recruiting

358

Pimavanserin, Quetiapine

VA Office of Research and Development

Parkinson's Disease Psychosis

10/25

08/26

NCT03465787: A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia

Completed

210

RoW

Lurasidone HCL 160 mg, Quetiapine XR 600 mg

Bukwang Pharmaceutical

Schizophrenia

10/22

SEP361-304, NCT04115319 / 2019-002259-40: A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

Completed

475

Europe, US, RoW

SEP363856, quetiapine XR, Seroquel XR

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

12/22

NCT04513912 / 2020-000341-14: A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Completed

757

Europe, Canada, US, RoW

Seltorexant, Matching placebo to Seltorexant, Quetiapine XR, Matching placebo to Quetiapine XR

Janssen Research & Development, LLC

Depressive Disorder, Major

10/23

ChiCTR2200066465: Bioequivalence of Quetiapine Fumarate Extended-release Tablets (Fasting /Feeding) in Healthy Human Body: a Randomized Cross-Over Controlled Trial

Not yet recruiting

In the morning of period I, participants received a single dose of test preparation after an overnight fast. In the period Ⅱ, participants crossed a single dose of reference preparation according to the randomized grouping table. ;In the morning of period I, participants received a single dose of reference preparation after an overnight fast. In the period Ⅱ, participants crossed a single dose of test preparation according to the randomized grouping table. ;In the morning of period I, participants received a single dose of test preparation after a high fat meal. In the period Ⅱ, participants crossed a single dose of reference preparation according to the randomized grouping table. ;In the morning of period I, participants received a single dose of reference preparation after a high fat meal. In the period Ⅱ, participants crossed a single dose of test preparation according to the randomized grouping table.

Xiangya Boai Rehabilitation Hospital; Europharm Laboratoires Co., Ltd., Europharm Laboratoires Co., Ltd.

Pharmacokinetics and Bioequivalence Study in human

NCT00710918: Quetiapine Compared With Placebo in the Management of Fibromyalgia

Recruiting

N/A

quetiapine, Seroquel XR, Placebo

East Tennessee State University Research Foundation

Fibromyalgia

06/11

12/11

mirtazapine / Generic mfg.

2006-003194-27: mirtazapine versus placebo in functional dyspepsia: a randomized, double-blind, placebo-controlled trial

Ongoing

Europe

mirtazapine, Orodispersible tablet, Remergon Soltab 15 mg

University Hospitals KU Leuven

functional dyspepsia diagnosed according to international consensus criteria ("Rome II criteria")

2009-016953-16: Depressions-Spektrums-Störung und differenzielle Effekte neuerer Antidepressiva auf die Verkehrssicherheit

Ongoing

120

Europe

Cipralex, Solvex, Remergil, Elontril, Valdoxan, Tablet, Cipralex, Solvex, Remergil, Elontril, Valdoxan

Inn-Salzach-Klinikum gGmbH

Spectrum of depressive diseases, ICD-10: F32.x, F33.x

ChiCTR-TRC-13003161: Clinical trials of antidepressant mirtazapine for the treatment of functional dyspepsia patients with weight loss

Completed

Group A is treated with conventional therapy during 8 weeks ;Group B is treated with conventional therapy in combination with Paroxetine during 8 weeks ;Group C is treated with conventional therapy in combination with Mirtazapine during 8 weeks

Guangzhou Nansha Central Hospital, Guangzhou First People's Hospital Affiliated to Guangzhou Medical College; Guangzhou Nansha Central Hospital, Guangzhou First People's Hospital Affiliated to Guangzhou Medical University, Self-funding

Functional Dyspepsia with Weight loss

2014-004862-89: The effect of mirtazapine (REMERGON®) an tetracyclic antidepressant on gastric movements and satiation in healthy subjects

Ongoing

Europe

mirtazapine, Film-coated tablet, REMERGON

KULeuven, KuLeuven

Functional Dyspepsia, the presence of dyspepsia in patients from which the cause of the gastric symptoms is unknown ( not organic nor metabolic), Diseases [C] - Digestive System Diseases [C06]

2004-002788-25: Hippocampal volume in young adults with moderate to severe depression before and after combined antidepressant therapy

Ongoing

160

Europe

Trevilor retard, Remergil Soltab, VENLA,

Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg

moderate to severe depression (episodes and recurrent diseases)

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

idazoxan (RX 781094) / Houston Pharma

NCT05727189: A Study of Idazoxan in Healthy Participants

Recruiting

150

RoW

Terran Biosciences Australia Pty Ltd

Healthy

03/24

Validive (clonidine MBT) / Monopar Therap

Not yet recruiting

2/3

260

Europe

Validive (Clonidine HCl mucoadhesive buccal tablet (MBT)), Muco-adhesive buccal tablet

Monopar Therapeutics Inc., Monopar Therapeutics Inc.

VOICE, NCT04648020 / 2021-000999-11: Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer.

Terminated

190

Europe, US

Clonidine HCl Mucoadhesive Buccal Tablet, Validive®, Placebo Mucoadhesive Buccal Tablet

Monopar Therapeutics, Monopar Therapeutics Inc.

Chemoradiotherapy-Induced Severe Oral Mucositis

05/23

maprotiline / Generic mfg.

Ongoing

1000

Europe

Universitätsklinikum Würzburg, Kompetenznetz TDM-KJP e.V., BfArM

Teluron (terguride) / Pfizer, ErgoNex

2015-002586-39: Terguride Plus Symptomatic Therapy in Patients with Diffuse Cutaneous Systemic Sclerosis

Ongoing

148

Europe

Terguride, /, Tablet, METOCLOPRAMIDE ACCORD - 10 MG COMPRESSE 28 COMPRESSE IN BLISTER PVC/PVDC/AL

medac GmbH, MEDAC GMBH, medac GmbH

Diffuse cutaneous systemic sclerosis (dcSSc), systemic sclerosis, Diseases [C] - Immune System Diseases [C20]

2009-017869-27: A dual-center, open-label Proof of Concept study to evaluate the efficacy of Terguride for the treatment of fibrosis in patients with systemic sclerosis.

Ongoing

Europe

Terguride, PR1,

University Hospital Zurich

Diffuse scleroderma

paliperidone extended release / Generic mfg.

ChiCTR-IPR-16009208: The safety of Paliperidone Extended-Release Tablets and Olanzapine in treating patients with schizophrenia

Recruiting

120

Paliperidone Extended-Release Tablets ;Olanzapine

The Seventh People's Hospital of Shaoxing City; the seventh people’s hospital of Shaoxing City, the seventh people’s hospital of Shaoxing City

schizophrenia

NCT04478838: "Extended" (Alternate Day) Antipsychotic Dosing

Recruiting

120

Canada

Risperidone, Risperdal, Olanzapine, Zyprexa, Apo-Olanzapine, Sandoz-Olanzapine, Invega Paliperidone

Centre for Addiction and Mental Health

Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents

09/27

09/28

Ongoing

Europe

Paliperidone ER, R076477,

Janssen L.P.

Schizoaffective disorder

Completed

N/A

paliperidone extended-release ;olanzapine

First Affiliated Hospital, College of Medicine, Zhejiang University; Level of the institution：, Key Medical Disciplines Funds in Zhejiang Province

Schizophrenia

ChiCTR-TRC-14004854: A randomized, controlled, multi-center clinical trial to study the treatment resistant schizophrenia (TRS) in Zhejiang province

Completed

N/A

200

Paliperidone Extended-Release Tablets ;Olanzapine

First Affiliated Hospital, Zhejiang University School of Medicine; None, self-financing

Schizophrenia

ChiCTR-TRC-14004452: The efficacy and safety of Paliperidone Extended-Release Tablets combined with sodium valproate in Bipolar disorder manic episode

Recruiting

N/A

200

PANSS ;Paliperidone Extended-Release Tablets combined with placebo ;Paliperidone Extended-Release Tablets combined with sodium valproate

First Affiliated Hospital, College of Medicine, Zhejiang University; First Affiliated Hospital, College of Medicine, Zhejiang University, National Natural Science Foundation (81301158)

Bipolar disorder

quetiapine / Generic mfg.

2007-004513-33: Comparative Evaluation of QUEtiapine-Lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in patients with bipolar depression

Ongoing

300

Europe

Dispersible tablet, Tablet, Lamictal, TillVal Folysra (Folic acid)

University of Oxford

Bipolar depression

ChiCTR2200061843: A 24-Week, Randomized, Open-Label, Haloperidol-Control Study to Evaluate the Efficacy of Quetiapine in Improving Social Cognitive Function of Patients with Schizophrenia

Completed

treatment with quetiapine ;treatment with haliperidol

Beijing Anding Hospital, Capital Medical University; Beijing Anding Hospital, Capital Medical University, Xi’An Janssen Pharmaceutical Ltd.

Schizophrenia

ChiCTR-TNRC-10001112: The study on clinical and biological characters of bipolar depression and the treatment scheme optimizing

Completed

640

Lithium, Sodium valproate, Lamotrigine, MECT, Sertraline, Citalopram, Escitalopram, venlafaxine, Quetiapine, Olanzapine, Risperidone, sulpiride

Guangzhou Scientific and Technological Bureau, Guangzhou Board of Health; Guangzhou first people's hospital, The Tackling Key Problems of Guangzhou Scientific and Technological Project

bipolar depressive disorder

ChiCTR-TRC-10000934: Pharmacogenomic study of schizophrenia

Completed

3000

Perphenazine 16-64 mg/d (N=250) or Haloperidol 6-20 mg/d (N=250) ;Risperidone 2-6mg/d ;Olanzapine 5-20 mg/d ;Quetiapine 400-750mg/d ;Aripiperazole 10~30 mg/d ;Ziprasidone 80-160 mg/d

The Sixth Hospital / Institute of Mental Health, Peking University; The Ministry of Science and Technology, The National High Technology Research and Development Program of China (863 program)

Schizophrenia

ChiCTR-IPR-16009475: The research of chronic insomnia clinical evaluation and optimization of treatment

Completed

100

alprazolam ;Zolpidem ;Trazodone ;Quetiapine

Shanghai Mental Health Center; Shanghai Mental Health Center, Shanghai science and technology committee

chronic insomnia

Ongoing

150

Europe

AstraZeneca Farmacéutica Spain, S.A.

Tratamiento del Episodio Maníaco Bipolar Tipo I

Ongoing

Europe

Seroquel®, 47291.00.00, 47291.01.00, 47291.02.00, Seroquel®, Seroquel®

Medical School of Hannover

2004-002608-13: Pragmatic Randomised Control Trial of Quetiapine for psychosis in Parkinson’s Disease

Ongoing

Europe

Seroquel, Seroquel, Seroquel

King’s College London & King’s College Hospital

Parkinson\'s Disease with psychosis

2005-005072-32: Is it possible to modify the course of manic relapse? A pilot study of the effectiveness of quetiapine in preventing the development of manic episodes in Bipolar Disorder.

Ongoing

Europe

Quetiapine, Seroquel 100mg, Seroquel 150mg, Seroquel 200mg, Seroquel 300mg, Seroquel 100mg, Seroquel 150mg, Seroquel 200mg, Seroquel 300mg

Kings College London (IOP) / South London and Maudsley NHS Trust (Co-sponsorship)

Bipolar Disorder

2006-001317-15: BALANCE 2: Bipolar disorder:Antidepressant/Lamotrigine/ANtipsychotic Comparative Evaluation

Ongoing

630

Europe

Selective Serotonin Reuptake Inhibitors, SSRI, Quetiapine, Lamotrigine, Quetiapine, Lamotrigine

University of Oxford

Bipolar depression.

Ongoing

Europe

Seroquel 25, Seroquel 100, Seroquel 300, Seroquel 25, Seroquel 100, Seroquel 300, Seroquel 25, Seroquel 100, Seroquel 300

Klinikum Fulda gAG

Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.

2007-000579-40: Effects of atypical versus typical neuroleptics on motivation, hedonia, and social cognition in patients with schizophrenia – an fMRI study

Ongoing

Europe

Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal, Seroquel, Haloperidol Hexal

Charité Universitätsmedizin Berlin

Schizophrenia

2007-004528-19: Electrophysiological measurement of anterior cingulate cortex (ACC) function in schizophrenic patients treated with Seroquel® or Fluanxol®

Ongoing

Europe

Seroquel (Quetiapine), Fluanxol (Flupentixol), Seroquel, Fluanxol, Seroquel, Fluanxol

University of Wuerzburg

schizophrenia (295.10, 295.20, 295.30, 295.90 according to Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV)

2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD

Ongoing

300

Europe

Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary)

King\'s College London, North Essex Partnership NHS Foundation Trust

Alzheimer\'s disease

2013-003460-31: The effect of low doses of mirtazapine and quetiapine on sleep and daytime functioning.

Ongoing

Europe

mirtazapine, quetiapine, n/a,

GGZ-Drenthe, GGZ-Drenthe

Insomnia

2016-001637-27: Lithium versus Quetiapine in Treatment Resistant Depression.

Ongoing

276

Europe

Lithium carbonate, Quetiapine, Lithium citrate, Tablet, Syrup

South London and Maudsley NHS Foundation Trust, King's College London, National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme

Not yet recruiting

512

Europe

University Medical Center Groningen, ZonMw

2017-004602-17: Digital Medicine System

Not yet recruiting

Europe

DM-Aripiprazole, DM-Olanzapine, DM- Quetiapine, DM-Risperidone, Tablet, Aripiprazole, Olanzapine, Quetiapine, Risperidone

Otsuka Pharmaceutical, Otsuka Pharmaceutical

Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03]

ChiCTR1800014755: Study on individualized optimal treatment for antipsychotic drugs

Recruiting

2000

Risperidone ;Olanzapine ;Aripiperazole ;Quetiapine

国家科技部; Peking University Sixth Hospital, The Ministry of Science and Technology

Schizophrenia

LQD, NCT03004521: Lithium Versus Quetiapine in Treatment Resistant Depression

Recruiting

276

Europe

Quetiapine, Lithium

Depressive Disorder, Treatment-Resistant

04/21

08/21

NCT04446234: Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building

Not yet recruiting

350

RoW

Risperidone, Aripiprazole, Ziprasidone, Amisulpride, Quetiapine

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine

Schizophrenia

12/22

NCT04513314: Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium

Withdrawn

Valproate, Depakote, Valproic acid, Quetiapine, seroquel, Standard of Care, Hospital Protocol

University of Miami

Covid19, Hyperactive Delirium, Pneumonia, Viral

03/23

ChiCTR2100049426: A randomized and controlled study of ruracidone in the treatment of bipolar depression in adolescents and early adulthood

Not yet recruiting

treatment with lurasidone ;treatment with quetiapine

Beijing AnDing Hospital, Capital Medical University; Beijing AnDing Hospital, Capital Medical University, Beijing Hospital Authority

bipolar disorder

TraQ, NCT05085808: RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium

Not yet recruiting

Trazodone, Desyrel, Quetiapine, Seroquel, Placebo

University of Southern California

Delirium, Morality, Quality of Life, Psych, Treatment Side Effects

07/26

12/26

ChiCTR2200064086: The clinical efficacy of Quetiapine in the treatment of PD hallucinations and the mechanism of electrophysiology and brain imaging

Not yet recruiting

Quetiapine ;none ;none

Nanjing Brain Hospital; Nanjing Brain Hospital, crosswise tasks

Parkinson's disease with hallucinations

CAMELOT, NCT05590637: Comparing Antipsychotic Medications in LBD Over Time

Recruiting

Pimavanserin, Nuplazid, Quetiapine, Seroquel

The University of Texas Health Science Center at San Antonio, Alzheimer's Association

Parkinson's Disease Psychosis, Dementia With Lewy Bodies

08/25

02/26

NCT05741502: An Exploratory Analysis of Immune and Inflammatory Response Associated with Clozapine

Recruiting

Clozapine, Antipsychotics,Other (non-Clozapine), Including Olanzapine, Risperidone, Paliperidone, Quetiapine, Aripiprazole, Ziprasidone, Lurasidone, Cariprazine, and all Typical antipsychotics

Ohio State University

Treatment-resistant Schizophrenia

03/26

06/26

NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder

Not yet recruiting

Sultan Qaboos University

Panic Disorder

12/26

2005-003251-13: Quetiapine Augmentation In Treatment-Resistant Depression – An Open Pilot Study

Ongoing

Europe

Seroquel, Seroquel 25 mg, Seroquel 100 mg, Seroquel 150 mg, Seroquel 200 mg, Seroquel 300 mg, Seroquel 25 mg, Seroquel 100 mg, Seroquel 150 mg, Seroquel 200 mg, Seroquel 300 mg

AstraZeneca UK Ltd

Depression

2009-011253-40: Paroxetine or Quetiapine in Addition to Mood Stabilizers in Bipolar Depression

Ongoing

Europe

DAPAROX*28CPR RIV 20MG PVC/PE/, SEROQUEL*60CPR RIV 100MG, DAPAROX*28CPR RIV 20MG PVC/PE/, SEROQUEL*60CPR RIV 100MG

AZIENDA SANITARIA OSPEDALIERA \"S. GIOVANNI BATTISTA DI TORINO\"

Major Depressive Episode in Bipolar Disorder

Ongoing

Europe

Fundación Institut de Recerca de l\' Hospital de la Santa Creu i Sant Pau

Depresión mayor resistente a Inhibidores Selectivos de la Recaptación de serotonina,Código de clasificación de la CIE : F-33

Not yet recruiting

350

Europe

Capsule, Quetiapina NORMON 25 mg comprimidos recubiertos con peícula EFG

IBSAL (Instituto de Investigación Biomédica de, IBSAL, GRUPO DE RECUPERACION MULTIMODAL ESPAÑOL

NCT05690698: Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium

Completed

100

RoW

Quatiapine, Haloperidol

Alexandria University, Suez Canal University, Gezira University

Hyperactive Delirium

07/23

NCT06482554: Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms.

Recruiting

Lumateperone 42 mg, Lumateperone, Risperidone 2 mg, olanzapine; quetiapine; ziprasidone; aripiprazole

Louisiana State University Health Sciences Center Shreveport

Apathy, Schizophrenia, Schizophrenia; Psychosis

12/26

NCT06333990: Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

Recruiting

146

Quetiapine Fumarate, Seroquel, TAU, Treatment As Usual

Foundation for Advancing Veterans' Health Research, The University of Texas Health Science Center at San Antonio, Biomedical Research Institute of New Mexico

Mild Traumatic Brain Injury

06/28

Recruiting

418

Europe

Escitalopram, ATC code: N06AB10, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04

Dr. Inge Winter, Universität Münster

Bipolar Depression

06/26

INTENSIFY, NCT05603104: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure

Recruiting

1254

RoW

Dr. Inge Winter, Universität Münster

Schizophrenia and Related Disorders, Major Depressive Disorder, Bipolar Depression

06/26

Ongoing

2/3

196

Europe, RoW

Evenamide, NW3509, Capsule, hard

Newron Pharmaceuticals S.p.A., NEWRON PHARMACEUTICALS SPA, Newron Pharmaceuticals S.p.A, Newron Pharmaceuticals S.p.A., Newron Pharmaceuticals S.p.A

Chronic schizophrenia, Chronic schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03]

Not yet recruiting

2/3

Europe

Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI), Consejería de salud

Early schizophrenia Esquizofrenia temprana, Newly evolving schizophrenia Esquizofrenia de reciente evolución, Psychiatry and Psychology [F] - Mental Disorders [F03]

MEL-QUE, NCT06062953: Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients with Psychiatric Disorders and Comorbid Insomnia

Recruiting

2/3

255

Europe

Melatonin, Quetiapine, Placebo

Lone Baandrup, Danish Center for Sleep Medicine, Region Capital Denmark, Copenhagen Trial Unit, Center for Clinical Intervention Research, Mental Health Services in the Capital Region, Denmark

Psychiatric Disorders, Insomnia

02/29

Not yet recruiting

1200

Royal Melbourne Hospital, The Australian and New Zealand Intensive Care Foundation

critical illness, hyperactive delirium

ACTRN12624001075572: A single centre pilot randomised controlled trial of enteral Guanfacine vs Quetiapine for agitated delirium in patients in the intensive care unit

Recruiting

Austin Hospital, Austin Health

Agitated delirium

Ongoing

Europe

AZD3480,

AstraZeneca AB

Schizophrenia

NCT05793632: Quetiapine in Prevention of Delirium

Completed

RoW

Quetiapine

Ain Shams University

Delirium

04/23

QOSA, NCT05303935: Effects of Quetiapine on Sleep and Next Day Alertness in People With Obstructive Sleep Apnea

Completed

RoW

Quetiapine 50 MG, Seroquel, Placebo, Sugar pill

Flinders University

Sleep Apnea, Obstructive

04/23

NCT04521478 / 2019-004264-21: A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Completed

389

Europe, Canada, Japan, US, RoW

BI 1358894, Placebo, Quetiapine

Boehringer Ingelheim

Depressive Disorder, Major

01/24

02/24

NCT04280965: Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury

Completed

Quetiapine Fumarate, Seroquel, Standard of care meducations

The University of Texas Health Science Center at San Antonio, South Central MIRECC

Post Traumatic Stress Disorder

04/22

10/22

NCT04950868: The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression

Active, not recruiting

Canada

Quetiapine

Verinder Sharma

Postpartum Depression

06/25

Completed

SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

09/23

NCT05542264: A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia

Completed

SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

02/24

NCT05240261: Sleep Disorders in Chronic Kidney Disease Patients

Not yet recruiting

Quetiapine

Assiut University

Chronic Kidney Diseases

05/24

12/24

NCT06546358: Quetiapine Versus Trazadone in Women With Postpartum Depression

Not yet recruiting

Canada

Trazodone, Teva-Trazadone, Quetiapine, Quetiapine Fumarate

Lawson Health Research Institute

Postpartum Depression

09/25

12/25

ChiCTR2100054147: Correlation between dopamine receptor gene polymorphism and clinical effect of bipolar depressive episode

Not yet recruiting

180

Lamotrigine ;Quetiapine ;Bupropion ;None

Jiaxing Kangci Hospital; Jiaxing Kangci Hospital, Provincial Health Commission, Jiaxing Kangci Hospital, self-funded

Bipolar depression

ChiCTR-TRC-14004814: A randomized controlled trial of repetitive transcranial magnetic stimulation combined with quetiapine in the first-episode bipolar II depressive episode

Completed

N/A

quetiapine+false TMS treatment ;quetaipine+rTMS high-frequency ;quetaipine+rTMS low-frequency

The First Affiliated Hospital, Zhejiang University; The First Affiliated Hospital, Zhejiang University, Scientific research expenses

Bipolar II depressive episode

ChiCTR-IPR-16008425: Efficacy of quetiapine in behavioral and psychological symptoms of Alzheimer's disease patients

Not yet recruiting

N/A

120

Quetiapine ;Memantine

Changning Mental Health Center; Changning Mental Health Center, Key program of the Changning Science and Technology Committee

Alzheimer's disease

ChiCTR-COC-17011401: A study of gut microbiota, immunology, Imageology in patients with bipolar disorder

Recruiting

N/A

200

quetiapine monotherapy

First Affiliated Hospital, Zhejiang University School of Medicine; First Affiliated Hospital, Zhejiang University School of Medicine, Provincial Natural Science Foundation

Bipolar disorder

NCT06200584: Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics

Completed

N/A

140

RoW

Risperidone, neuroleptics, Olanzapine, Quetiapine, Risperidone and Vitamin D and Vitamin E, vitamin, Olanzapine and Vitamin D and Vitamin E, Quetiapine and Vitamin D and Vitamin E

Dr Rabia Arshad

Antipsychotics and Neuroleptics Toxicity

06/21

NCT05098353: Seroquel ® in Patients With Bipolar Disorder in Remission With Signs of Impaired Impulse Control

Recruiting

N/A

RoW

Quetiapine, Quetiapine - impulsivity

Bipolar Affective Disorder

11/21

12/21

NCT04209166: A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical Features

Recruiting

N/A

780

RoW

SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/ Serotonin and Norepinephrine Reuptake Inhibitors), SSRIs/SNRIs+Mood Stabilizer, SSRIs/SNRIs+Quetiapine, Usual Treatment

Major Depressive Disorder

10/22

SWITCH, NCT04312503: Observational Study on the Effect of Switch to Lurasidone in Subjects With Schizophrenia"

Completed

N/A

Europe

Lurasidone, Latuda, aripiprazole, olanzapine, quetiapine or risperidone

Aziende Chimiche Riunite Angelini Francesco S.p.A

Schizophrenia

10/22

ChiCTR2200059660: Clinical study of single intravenous injection of esmketamine combined with an oral antidepressant in the treatment of depressive disorde

Not yet recruiting

N/A

Beijing Chaoyang Hospital; Beijing Chaoyang Hospital, self-raised

Depression

NCT05801289: Quetiapine as Prophylaxis for Delirium in CABG

Recruiting

N/A

RoW

Quetiapine, Seroquel

Ain Shams University

Delirium

04/23

NCT05840861: Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders

Recruiting

N/A

RoW

Vortioxetine, Quetiapine

Central South University

Major Depressive Disorder, Bipolar Disorder

08/23

09/23

NCT05833399: Correlation of Genetic Variations With Clinical Response in Substance Use Disorder

Recruiting

N/A

200

RoW

Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone, Seroquel, Olapex, Remeron, Tegretol, Moodapex, Tryptizol, Neurazine and Apexidone.

Alexandria University

Substance Use Disorders, Substance Dependence

03/24

12/24

ChiCTR2400083720: Effect of value orientation on brain activation in depressive patients with psychotic symptoms

Recruiting

N/A

Sertraline and quetiapine plus value-oriented short-term psychotherapy; Sertraline and quetiapine

The Second Affiliated Hospital of Xinxiang Medical College; The Second Affiliated Hospital of Xinxiang Medical College, Henan Province key research and development project

depression with psychotic symptoms

ChiCTR2100054169: Early effects of rTMS on bipolar depression by the modulation of prefrontal-amygdala/striatal brain network

Not yet recruiting

N/A

120

Combination therapy with rTMS and quetiapine ;Combination therapy with sham stimulation and quetiapine

Shenzhen Kangning Hospital; Shenzhen Kangning Hospital, Shenzhen Kangning Hospital

Bipolar depression

NCT06581302: Magnetic Seizure Therapy for Psychotic Disorders

Not yet recruiting

N/A

RoW

Magnetic seizure therapy by Magnetic stimulator, Seizure therapy, Antipsychotic medications (such as olanzpine, risperidone, aripiprazole, quetiapine, amisulpride, etc), antipsychotics

Shanghai Jiao Tong University School of Medicine

Psychotic Disorders

12/25

PRHDTDCSTMDE, NCT05498441: Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) Treatment for Major Depressive Episode

Recruiting

N/A

120

RoW

High-Definition Transcranial Direct Current Stimulation (HD-tDCS), Antipsychotics, mood stabilizers, etc.

Jiangsu Province Nanjing Brain Hospital

Major Depressive Episode

12/24

ChiCTR2300075440: Researches on the clinical curative effect of Yin-enching and Heat-cleaning on the treatment of the prodromal phases of bipolar disorder

Not yet recruiting

N/A

Traditional Chinese medicine formula granules+Imitated tablets of quetiapine fumarate; Chinese herbal placebo+quetiapine fumarate tablets

Beijing Anding Hospital，Capital Medical University; Beijing Anding Hospital，Capital Medical University, Beijing Municipal Administration of Hospital Incubating Program

the prodromal phases of bipolar disorder

TQDelirium, NCT05307003: Trazodone vs. Quetiapine for the Treatment of ICU Delirium

Recruiting

N/A

Trazodone, Desyrel, Quetiapine, Seroquel

University of Southern California

Delirium, Delirium of Mixed Origin, Delirium, Sepsis Associated, Delirium in Old Age, Delirium Confusional State, Psych, Morality, Treatment Side Effects

08/25

12/25

NCT04728581: Improving Sleep After TKA Using Mirtazapine and Quetiapine

Not yet recruiting

N/A

165

Europe

Mirtazapine, Quetiapine, Placebo

St. Anna Ziekenhuis, Geldrop, Netherlands

Osteo Arthritis Knee, Insomnia

05/26

01/27

NCT03449472: Bariatric Surgery and Pharmacokinetics of Quetiapine

Recruiting

N/A

Europe

Quetiapine, Quetiapine fumarate

Norwegian University of Science and Technology, St. Olavs Hospital, Volvat Medisinsk Senter Stokkan, Namsos Hospital, Alesund Hospital

Obesity, Morbid

10/26

CLASS-BD, NCT05480150: Chinese Longitudinal and Systematic Study of Bioplar Disorder

Recruiting

N/A

10000

RoW

Escitalopram Oxalate Tablets, Lexapro, Quetiapine Fumarate Tablets, Seroquel, Lurasidone, Latuda

First Affiliated Hospital of Zhejiang University

Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic

12/26

ACTRN12616001227482: Thyroid tests in people who are taking quetiapine.

Recruiting

N/A

PathWest Laboratory Medicine, PathWest Laboratory Medicine

Mental health disorders, Schizophrenia, Bipolar disorder, Anxiety

ACTRN12616001242415: Thyroid tests in people who will be taking quetiapine.

Recruiting

N/A

PathWest Laboratory Medicine, PathWest Laboratory Medicine

Psychosis, treated with quetiapine, Mood disorders, treated with quetiapine, Agitation, treated with quetiapine

quetiapine extended-release / Generic mfg.

APQ-TRD, NCT04936126: Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression

Recruiting

150

RoW

Quetiapine, Amantadine, Pramipexole

All India Institute of Medical Sciences, Bhubaneswar, Indian Council of Medical Research

Treatment Resistant Depression

07/24

09/24

SMART-BD, NCT06433635: Sequential Multiple Assignment Randomized Trial for Bipolar Depression

Not yet recruiting

2726

Canada, US

Cariprazine, Vraylar, Aripiprazole/Escitalopram combination, Abilify/ Lexapro, Quetiapine, Seroquel, Lurasidone, Latuda

Massachusetts General Hospital, Patient-Centered Outcomes Research Institute

Bipolar I Disorder, Depression

02/30

C-SAPP, NCT04373317: Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Recruiting

358

Pimavanserin, Quetiapine

VA Office of Research and Development

Parkinson's Disease Psychosis

10/25

08/26

NCT03465787: A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia

Completed

210

RoW

Lurasidone HCL 160 mg, Quetiapine XR 600 mg

Bukwang Pharmaceutical

Schizophrenia

10/22

SEP361-304, NCT04115319 / 2019-002259-40: A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

Completed

475

Europe, US, RoW

SEP363856, quetiapine XR, Seroquel XR

Otsuka Pharmaceutical Development & Commercialization, Inc.

Schizophrenia

12/22

Completed

757

Europe, Canada, US, RoW

Seltorexant, Matching placebo to Seltorexant, Quetiapine XR, Matching placebo to Quetiapine XR

Janssen Research & Development, LLC

Depressive Disorder, Major

10/23

ChiCTR2200066465: Bioequivalence of Quetiapine Fumarate Extended-release Tablets (Fasting /Feeding) in Healthy Human Body: a Randomized Cross-Over Controlled Trial

Not yet recruiting

Xiangya Boai Rehabilitation Hospital; Europharm Laboratoires Co., Ltd., Europharm Laboratoires Co., Ltd.

Pharmacokinetics and Bioequivalence Study in human

NCT00710918: Quetiapine Compared With Placebo in the Management of Fibromyalgia

Recruiting

N/A

quetiapine, Seroquel XR, Placebo

East Tennessee State University Research Foundation

Fibromyalgia

06/11

12/11

mirtazapine / Generic mfg.

2006-003194-27: mirtazapine versus placebo in functional dyspepsia: a randomized, double-blind, placebo-controlled trial

Ongoing

Europe

mirtazapine, Orodispersible tablet, Remergon Soltab 15 mg

University Hospitals KU Leuven

functional dyspepsia diagnosed according to international consensus criteria ("Rome II criteria")

2009-016953-16: Depressions-Spektrums-Störung und differenzielle Effekte neuerer Antidepressiva auf die Verkehrssicherheit

Ongoing

120

Europe

Cipralex, Solvex, Remergil, Elontril, Valdoxan, Tablet, Cipralex, Solvex, Remergil, Elontril, Valdoxan

Inn-Salzach-Klinikum gGmbH

Spectrum of depressive diseases, ICD-10: F32.x, F33.x

ChiCTR-TRC-13003161: Clinical trials of antidepressant mirtazapine for the treatment of functional dyspepsia patients with weight loss

Completed

Functional Dyspepsia with Weight loss

2014-004862-89: The effect of mirtazapine (REMERGON®) an tetracyclic antidepressant on gastric movements and satiation in healthy subjects

Ongoing

Europe

mirtazapine, Film-coated tablet, REMERGON

KULeuven, KuLeuven

Functional Dyspepsia, the presence of dyspepsia in patients from which the cause of the gastric symptoms is unknown ( not organic nor metabolic), Diseases [C] - Digestive System Diseases [C06]

2004-002788-25: Hippocampal volume in young adults with moderate to severe depression before and after combined antidepressant therapy

Ongoing

160

Europe

Trevilor retard, Remergil Soltab, VENLA,

Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg

moderate to severe depression (episodes and recurrent diseases)

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