| pixatimod (PG545) / Zucero Therap |
NCT05061017: Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC) |
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| Completed | 2 | 14 | US | Pixatimod, (PG545), Nivolumab, OPDIVO®, Cyclophosphamide (low dose) | Diwakar Davar, Aculeus Therapeutics | NSCLC, Metastatic Colorectal Carcinoma, Refractory Melanoma | 02/24 | 03/24 | | |
| Defitelio (defibrotide) / IRCCS San Raffaele Hospital, Jazz |
| Completed | 2b | 156 | Europe | Defibrotide, Placebo | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | COVID19 | 02/23 | 02/23 | | |
NCT04313036: 5-day Defibrotide Treatment for Hepatic SOS/VOD |
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| Recruiting | 2 | 24 | US | Defibrotide | Loyola University | Sinusoidal Obstruction Syndrome, Veno-occlusive Disease, Bone Marrow Transplant Complications | 05/22 | 08/22 | | |
NCT03805581: Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome |
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| Completed | 2 | 20 | US | Defibrotide, Defitelio® | New York Medical College, Johns Hopkins University | Sickle Cell Disease, Acute Chest Syndrome | 07/22 | 11/23 | | |
NCT04777422: Defibrotide in Children With High Risk Kawasaki Disease |
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| Active, not recruiting | 2 | 2 | US | Defibrotide, Defitelio® | New York Medical College, Johns Hopkins University, Columbia University, New York University | Kawasaki Disease | 10/23 | 06/24 | | |
| Recruiting | 2 | 42 | US | Defibrotide | Brigham and Women's Hospital, Jazz Pharmaceuticals | Covid19 | 09/24 | 03/25 | | |
NCT06182410: Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma |
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| Withdrawn | 2 | 15 | NA | Defibrotide, Noravid | University of California, San Francisco, Jazz Pharmaceuticals | Transplant-Associated Thrombotic Microangiopathy, Neuroblastoma, High-risk Neuroblastoma, Thrombotic Microangiopathies | 05/27 | 05/27 | | |
NYMC-571, NCT02675959: Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease |
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| Recruiting | 2 | 40 | US | Defibrotide | New York Medical College, University of California, Los Angeles, Medical College of Wisconsin, Tufts Medical Center, Baylor College of Medicine, Johns Hopkins University, Dana-Farber Cancer Institute, Children's Hospital Los Angeles | Sickle Cell Disease | 12/24 | 12/25 | | |
| Recruiting | 2 | 20 | US | Defibrotide, Defitelio | New York Medical College | Sinusoidal Obstruction Syndrome, Veno-occlusive Disease | 08/26 | 08/27 | | |
NCT00263978: Defibrotide Compassionate Use for Patients With Life Threatening Veno-Occlusive Disease of the Liver |
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| No Longer Available | N/A | | US | Defibrotide | Emory University | Liver Diseases | 06/09 | 06/09 | | |
NCT00143546: Compassionate Use of Defibrotide for Patients With Veno-occlusive Disease of the Liver |
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| No Longer Available | N/A | | US | Defibrotide, Veno-occlusive disease, VOD, Hepatic veno-occlusive disease. | St. Jude Children's Research Hospital | Hepatic Veno-occlusive Disease | | | | |
| roneparstat (LB401) / Leadiant Biosci |
| No trials found |
