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Journal, IO biomarker:
CD277 agonist enhances the immunogenicity of relapsed/refractory acute myeloid leukemia towards Vδ2 T cell cytotoxicity.
(Pubmed Central) - Sep 14, 2022
These findings suggest a decisive role of CD277 in mediating the recognition of R/R AML cells by Vδ2 T cells. CD277 agonist combining adoptive transfer of Vδ2 T cells may improve the efficacy in the treatment of R/R AML.