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- | Journal: MicroRNA-181a-5p Curbs Osteogenic Differentiation and Bone Formation Partially Through Impairing Runx1- Dependent Inhibition of AIF-1 Transcription. (Pubmed Central) - Jan 7, 2023
Tail vein injection of a miR-181a-5p antagonist induced bone formation in OVX-induced osteoporotic mice. In conclusion, miR-181a-5p affects osteogenic differentiation and bone formation partially via the modulation of the Runx1/AIF-1 axis.
- | Journal: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria. (Pubmed Central) - Feb 5, 2021
In addition, we found that EFhd1 has Ca-independent β-actin-binding and Ca-dependent β-actin-bundling activities. These findings suggest that EFhd1, an actin-binding and -bundling protein in the mitochondria, may contribute to the Ca-dependent regulation of mitochondrial morphology and energy synthesis.
- | Bay11-7082 / InvivoGen
Journal: Role of allograft inflammatory factor-1 in the regulation of inflammation and oxidative stress in primary peritoneal mesothelial cells. (Pubmed Central) - Sep 11, 2019
Additionally, AIF-1-evoked inflammation in peritoneal mesothelial cells was attenuated by the addition of NF-κB inhibitor (BAY 11-7082). In brief, this study provides us novel information to understand the molecular regulation mechanisms of AIF-1 in peritoneal fibrosis.