- |||||||||| Journal, IO biomarker: AAMP is a binding partner of costimulatory human B7-H3. (Pubmed Central) - Aug 4, 2022
Finally, an interaction between AAMP and B7-H3 could be observed on expression level, hinting toward a combined synergistic effect. AAMP was identified as a novel interaction partner of B7-H3, opening new possibilities to create a targeted therapy against the pro-tumorigenic costimulatory protein B7-H3.
- |||||||||| Journal: MicroRNA-125b inhibits the proliferation of vascular smooth muscle cells induced by platelet-derived growth factor BB. (Pubmed Central) - Jun 8, 2021
Furthermore, western blot and immunofluorescence analyses demonstrated that AAMP and SRF expression levels decreased following transfection with miR-125b mimic compared with the NC group, the effects of which were reversed following transfection with miR-125 inhibitor. Taken together, the results of the present study suggested that miR-125b inhibits the proliferative and migratory abilities of VSMCs by regulating the expression levels of AAMP and SRF.
|