||||||||||Journal: Oxidative stress creates a unique, CaMKII-mediated substrate for atrial fibrillation in heart failure. (Pubmed Central) - Nov 23, 2019 Computational modeling illustrated how conduction slowing (e.g., due to increase in CaMKII-p-Nav1.5) interacts with fibrosis to cause reentry in the PLA. We conclude that OS via CaMKII leads to substrate for triggered activity and reentry in HF PLA by mechanisms independent of but complementary to fibrosis.