||||||||||Journal: 2,3-Dihydrobenzo-dioxine piperidine derivatives as potent and selective α2c antagonists. (Pubmed Central) - May 31, 2022 No abstract available In this manuscript, we report a series of benzodioxine methyl piperidine derivatives as highly potent and selective α2C antagonists by ligand design to improve the pharmacokinetics of a previous candidate molecule.