- |||||||||| Journal: Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities. (Pubmed Central) - Nov 27, 2023
Conclusion From these results, FCA is proposed as a useful functional ingredient to alleviate atopic dermatitis through skin topical application and oral administration. WT-29 isolated from Wedelia exerts anti-inflammatory and anti-allergic effects mainly through NF-?B, Nrf2/Keap-1, MAPK pathways and regulating of autophagy, suggesting that it might be a potential anti-inflammatory and anti-allergic agent and could be used as medicine or health benefit product.
- |||||||||| Propolis (Exhibit Hall; Poster Board No. P715) - Apr 11, 2023 - Abstract #IMMUNOLOGY2023IMMUNOLOGY_1223;
Median duration of serum-free IgE concentration maintained at < 82.8 ng/mL increased with increasing dose of YH35342 and were longer in all YH35324 dose groups than in the omalizumab and placebo groups (P<0.05). Keywords: Propolis, mast cell, anaphylaxis, histamine,
- |||||||||| Journal: Humulene Inhibits Acute Gastric Mucosal Injury by Enhancing Mucosal Integrity. (Pubmed Central) - Jun 3, 2021
α-Humulene may attenuate HCl/ethanol-induced gastritis by inhibiting histamine release and NF-κB activation and stimulating antioxidants and mucosal protective factors, particularly Muc5ac and Muc6. Therefore, these data suggest that α-humulene is a potential drug candidate for the treatment of stress-induced or alcoholic gastritis.
- |||||||||| Journal: Tripterine is a potential anti-allergic compound. (Pubmed Central) - Feb 9, 2021
This comprehensive review serves as a useful resource for medicinal plants with anti-allergic rhinitis potential, understanding the underlying mechanisms of action and for future exploration to find natural product candidates in the development of novel anti-allergic rhinitis agents. TRI, as an active immunoregulatory factor, has great potential in the treatment of mast cell-mediated allergic diseases.
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