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pentylenetetrazole
(BTD-001) /
Balance Therap
Journal:
D-limonene Inhibits Pentylenetetrazole-Induced Seizure via Adenosine A2A Receptor Modulation on GABAergic Neuronal Activity.
(Pubmed Central) - Mar 9, 2021
These results suggest that D-limonene exhibits anticonvulsant activity through modulation of adenosine A2A receptors on GABAergic neuronal function.
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[VIRTUAL] A COMPUTATIONAL CHEMOGENOMICS METHOD FOR THE PREDICTION OF OFF-TARGET INTERACTIONS WITH COAGULATION FACTOR XA
() - May 16, 2020 - Abstract #EHA2020EHA_1937;
Conclusion Factor Xa is a direct target of anticoagulant drugs, however, undesired interaction may cause adverse effects, such as hemorrhage. Our in silico method may be useful for the prediction of off-targets in the early drug discovery process