| Recruiting | 3 | 330 | Europe | Clarithromycin 500mg, A β-lactam/β-lactamase inhibitor or a 3rd generation cephalosporin or a fluoroquinolone, Tablets | Hellenic Institute for the Study of Sepsis | Community-acquired Pneumonia | 11/25 | 01/26 | | |
MODIFY, NCT05909683: Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the Trial) |
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| Recruiting | 3 | 190 | Europe | Change of antimicrobials based on BCID2 and Reveal Rapid AST tests. Stop of antimicrobials based on PCT results., Standard of Care | Hellenic Institute for the Study of Sepsis | Sepsis | 07/25 | 07/25 | | |
| Completed | 2 | 44 | Europe | Bezlotoxumab, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians., Normal saline 0.9% or 5% dextrose water, Standard-of-care treatment according to local guidelines or to the decision of the attending physicians | Hellenic Institute for the Study of Sepsis | Clostridioides Difficile Infection, Stool Microbiome, Organ Dysfunction Syndrome, Clostridioides Difficile Infection Recurrence, Mortality | 06/23 | 06/23 | | |
