University Clinical Center Kragujevac Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Li, Ping

NCT06381323: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Recruiting

RoW

Finerenone, Nifedipine

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Primary Aldosteronism, Finerenone, Mineralocorticoid Receptor Antagonist

03/27

04/27

NCT06256289: Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome

Not yet recruiting

Canagliflozin 100mg Tab, Invokana, Metformin Hydrochloride, Glucophage

Ping Li,MD

Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease

04/25

NCT04939441: Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF)

Active, not recruiting

100

RoW

Tenofovir alafenamide, Vemlidy®

Jidong Jia, Beijing Ditan Hospital, ShuGuang Hospital, Tianjin Third Central Hospital, Huashan Hospital, The Sixth Peoples Hospital of Zhengzhou, Tianjin Second People's Hospital, Ruijin Hospital, Shanghai East Hospital

Chronic Hepatitis B

05/24

05/25

NCT05814770: Comparing the Efficacy and Safety of Finerenone and Spironolactone in the Treatment of Primary Aldosteronism

Not yet recruiting

Finerenone, Kerendia, Spironolactone

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, National Key Research and Development Program of China, National Natural Science Foundation of China

Primary Aldosteronism, Hypertension

03/25

03/26

NDKD, NCT06110130: Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With

Recruiting

Empagliflozin 10 MG, Placebo

Washington D.C. Veterans Affairs Medical Center, Boehringer Ingelheim

Chronic Kidney Diseases

12/25

12/26

NCT05182463: Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients

Recruiting

5000

RoW

Peginterferon Alfa-2B, Nucleoside Analogs

Third Affiliated Hospital, Sun Yat-Sen University

Hepatitis B, Chronic

12/26

11/29

NCT04373967: Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 Diabetes

Recruiting

424

RoW

Victoza®., Metformin Hydrochloride, TQZ2451

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Type 2 Diabetes

12/21

RECAM, NCT04807348: Chiglitazar Added to Metformin for Type 2 Diabetes

Completed

533

RoW

Chiglitazar 32mg, Bilessglu, CS038, Chiglitazar 48mg, Placebo, Chiglitazar simulator, Metformin Hydrochloride, Glucophage

Chipscreen Biosciences, Ltd.

Type 2 Diabetes

02/23

NCT06280716: A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis

Recruiting

430

RoW

Placebo, Lebrikizumab, LY3650150, Topical Corticosteroid

Eli Lilly and Company

Atopic Dermatitis

12/25

11/26

TRAPP, NCT05811676: Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women with Placenta Previa

Recruiting

1680

RoW

Tranexamic acid, 0.9% sodium chloride

Guangzhou Medical University, Dongguan Maternal and Child Health Care Hospital, Foshan Women and Children Hospital, BoAi Hospital of Zhongshan, Women and Children's Hospital of Chongqing Medical University, Tianjin Central Hospital of Gynecology Obstetrics, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Urumqi Maternal and Child Health Care Hospital, Zhuhai Women and Children's Hospital, The First Affiliated Hospital of Zhengzhou University, Hunan Provincial Maternal and Child Health Care Hospital, Dalian women and children's medical group, Nanfang Hospital, Southern Medical University, Huadu District People's Hospital of Guangzhou, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, First Affiliated Hospital, Sun Yat-Sen University, Shenzhen Maternity & Child Healthcare Hospital, Shenzhen Baoan Women's and Children's Hospital, Dongguan People's Hospital, First Affiliated Hospital of Xinjiang Medical University, Tongji Hospital, Peking Union Medical College, Peking University First Hospital, The First Affiliated Hospital of Guangzhou Medical University, Second Affiliated Hospital of Guangzhou Medical University, Fifth Affiliated Hospital of Guangzhou Medical University, Shijiazhuang Obstetrics and Gynecology Hospital

Hemorrhage, Postpartum, Placenta Previa

02/25

04/25

NCT06631170: Efficacy and Safety of Roflumilast Cream in Subjects with Atopic Dermatitis

Recruiting

351

RoW

Roflumilast Cream 0.15%, Vehicle cream

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.

Atopic Dermatitis (AD)

08/25

ACHIEVE, NCT04808752: Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases

Active, not recruiting

RoW

Almonertinib, Investigational Product

Zhejiang Cancer Hospital, Jiangsu Hansoh Pharmaceutical Co., Ltd.

Lung Cancer

06/24

07/24

NCT06677879: A Prospective Cohort Study of Proton and Photon Therapy for Left-sided Breast Cancer.

Recruiting

780

RoW

Proton radiotherapy, Photon radiotherapy

Shanghai Proton and Heavy Ion Center

Breast Cancer

07/26

07/28

TQB3702-II-02, NCT06566586: A Clinical Study to Evaluate the Efficacy and Safety of TQB3702 Tablets Combined With Immunochemotherapy for the Treatment of B-cell Lymphoma

Recruiting

RoW

TQB3702 tablets+Chemotherapy regimen

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

B-cell Lymphoma

03/26

12/27

SPHIC-TR-PCa2021-01, NCT05106699: Carbon Ion Followed by Proton Radiotherapy for Prostate Cancer With Pelvic Lymph Nodes Metastases

Recruiting

RoW

proton plus carbon ion radiation

Shanghai Proton and Heavy Ion Center

Prostate Cancer

05/25

05/26

SPHIC-TR-PCa2020-01, NCT05010343: Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer

Recruiting

140

RoW

carbon ion irradation, Carbon Ion Irradiation With SIB

Shanghai Proton and Heavy Ion Center

Localized Prostate Cancer

07/25

07/28

PALIZADE, NCT05781750: A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis

Suspended

279

Europe, US, RoW

zetomipzomib, KZR-616, placebo, matching placebo

Kezar Life Sciences, Inc.

Lupus Nephritis

05/26

07/26

SPHIC-TR-BCa2022-02, NCT05692674: A Prospective Phase II Study for Adjuvant Hypofractionated Intensity-modulated Proton Radiotherapy for Post Operative Breast Cancer With Implantation Reconstruction

Recruiting

RoW

adjuvant hypofractionated intensity-modulated proton radiotherapy

Shanghai Proton and Heavy Ion Center

Breast Cancer

09/28

PM8002-A001, NCT05918445: PM8002 in the Treatment of Patients With Advanced Solid Tumors

Recruiting

1/2

380

RoW

PM8002

Biotheus Inc.

Malignant Neoplasm

11/25

SPHIC-TR-PCa2019-01, NCT04724577: 12 Fractions Carbon Ion Radiotherapy for Localized Prostate Cancer

Recruiting

RoW

carbon ion radiotherapy

Shanghai Proton and Heavy Ion Center

Radiotherapy, Prostate Cancer

12/22

06/23

NCT06375161: Anti-CD19-CAR-T Cells in Relapsed/Refractory B-cell Tumor Patients.

Recruiting

RoW

anti-CD19-CAR-T cells

Shanghai Tongji Hospital, Tongji University School of Medicine

B Cell Malignancies

12/25

12/39

NCT04606433: Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia

Recruiting

RoW

GNC-038

Sichuan Baili Pharmaceutical Co., Ltd., SystImmune Inc.

Non Hodgkin Lymphoma, Acute Lymphoblastic Leukemia

06/25

11/25

TQB2223-I-01, NCT05894421: TQB2223 Injection in Combination With Penpulimab in Patients With Advanced Cancers

Recruiting

RoW

TQB2223 injection+ Penpulimab Injection

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Advanced Cancer

01/25

01/26

NCT05924750: A Study of BL-M11D1 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting

RoW

BL-M11D1

Sichuan Baili Pharmaceutical Co., Ltd.

Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)

08/25

SPHIC-TR-BCa2022-01, NCT05692661: A Dose Escalation Study of Proton and Carbon Ion Irradiation for HER2 Positive and Triple Negative Breast Cancer

Recruiting

RoW

proton plus carbon ion radiotherapy

Shanghai Proton and Heavy Ion Center

Triple Negative Breast Cancer, HER2-positive Breast Cancer

10/25

01/26

CHESS1901, NCT03990753: Microbiome/Peptidome-based Model for Non-invasive Detection of High-risk Gastroesophageal Varices in Compensated Cirrhosis (/APPHA1901)

Recruiting

N/A

1000

RoW

esophagogastroduodenoscopy

Nanfang Hospital of Southern Medical University, Southern Medical University, China, LanZhou University, Zhongda Hospital, Medical School, Southeast University, Guangdong Second Provincial General Hospital, Xingtai People's Hospital, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Tianjin Second People's Hospital, Zhejiang University Lishui Hospital, The Second Hospital of Anhui Medical University, The Sixth People's Hospital of Shenyang, Xi'an Gaoxin Hospital, King Chulalongkorn Memorial Hospital affiliated to Chulalongkorn University, Ankara University

Compensated Cirrhosis

06/21

06/22

ETRAS-China, NCT03080519: Endovascular Therapy for Renal Artery Stenosis in China

Not yet recruiting

N/A

5000

RoW

Endovascular Therapy

Chinese Academy of Medical Sciences, Fuwai Hospital

Renal Artery Obstruction, Hypertension, Renovascular

04/22

04/24

NCT04108169: Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.

Recruiting

N/A

240

RoW

Left atrial appendage occlusion surgery

Beijing Institute of Heart, Lung and Blood Vessel Diseases

Heart Surgery

10/22

01/23

NCT02739659: Carbon Ion Radiotherapy for the Treatment of Localized Prostate Cancer

Recruiting

N/A

RoW

carbon-ion radiotherapy

Shanghai Proton and Heavy Ion Center

Prostate Carcinoma

12/22

12/24

NCT05392712: Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis

Recruiting

N/A

430

RoW

Magnetometer

Qilu Hospital of Shandong University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Weifang People's Hospital, Linyi People's Hospital, Jining First People's Hospital, The First Affiliated Hospital with Nanjing Medical University, Second Affiliated Hospital, School of Medicine, Zhejiang University, First Affiliated Hospital Xi'an Jiaotong University, Chongqing Emergency Medical Center, Guangdong Provincial Hospital of Traditional Chinese Medicine, First People's Hospital of Hangzhou, Central hospital Affiliated to Shandong First Medical University, Weihai Central Hospital, Heze Municipal Hospital

Chest Pain, Acute Coronary Syndrome, Myocardial Infarction

08/24

12/24

NCT06142175: Relmacabtagene Autoleucel in Patients With LBCL

Recruiting

N/A

200

RoW

Relmacabtagene Autoleucel, JWCAR029

Shanghai Ming Ju Biotechnology Co., Ltd.

Large B-cell Lymphoma

12/24

ASORPWICE, NCT03521739: Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events

Recruiting

N/A

100000

RoW

Chinese Academy of Medical Sciences, Fuwai Hospital

Blood Pressure, Pulse Wave Analysis, Ankle Brachial Index, Patient Outcome Assessment

12/22

12/23

NCT04833192: Evaluation of New Diagnostic Indicator of Subclinical Hypercortisolism

Recruiting

N/A

202

RoW

experimental group

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Adrenal Incidentaloma, Subclinical Hypercortisolism

04/23

12/23

NCT05826080: Effect of Adrenocorticotropic Hormone Stimulation During Adrenal Vein Sampling in Primary Aldosteronism

Recruiting

N/A

RoW

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Primary Aldosteronism, Aldosterone-Producing Adenoma, Idiopathic Hyperaldosteronism

10/23

09/24

NCT05896826: Magnetocardiography in the Accurate Identification of Myocardial Infarction

Recruiting

N/A

500

RoW

Magnetometer

Qilu Hospital of Shandong University, Chongqing Emergency Medical Center, Weifang People's Hospital, Linyi People's Hospital, Weihai Central Hospital, Jining First People's Hospital, The First Affiliated Hospital with Nanjing Medical University, Second Affiliated Hospital, School of Medicine, Zhejiang University, First Affiliated Hospital Xi'an Jiaotong University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Central hospital Affiliated to Shandong First Medical University, Heze Municipal Hospital, First People's Hospital of Hangzhou

Chest Pain, Acute Coronary Syndrome, Myocardial Infarction

10/24

12/24

NCT05021406: Extension Study of Carvedilol RCT Study

Recruiting

N/A

240

RoW

Carvedilol 12.5 MG, Nucleos(t)ide Analogues

Beijing Friendship Hospital

Liver Cirrhosis, Portal Hypertension

10/24

TAILOR-TAVR, NCT05511792: Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0)

Recruiting

N/A

206

RoW

TAVR for BAV Using Down Sizing with the Evolut Pro platform, Down Sizing Strategy, TAVR for BAV Using Traditional Sizing strategy with the Evolut Pro platform, Standard Sizing Strategy

Second Affiliated Hospital, School of Medicine, Zhejiang University

Aortic Stenosis With Bicuspid Valve

06/25

06/29

NCT04995159: Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVasâ„¢ BRS System

Not yet recruiting

N/A

2150

RoW

Single anti-platelet therapy, SAPT strategy, Dual anti-platelet therapy, DAPT strategy

Lepu Medical Technology (Beijing) Co., Ltd.

Coronary Heart Disease

01/26

01/28

NCT03261934: Risk Assessment and Syndrome Evolution Models for Chronic Atrophic Gastritis Malignant Transformation

Recruiting

N/A

2000

RoW

No intervention

Beijing University of Chinese Medicine, The University of Science and Technology of China, China Academy of Chinese Medical Sciences, Harvard Medical School (HMS and HSDM)

Risk Assessment of Chronic Atrophic Gastritis Malignant Transformation

12/30

ACTRN12622000019707: Effects of recorded maternal voice on heart rate and anthropometric parameters in premature infants: A randomized controlled trial

Completed

N/A

108

Ping Li, Ping Li

heart rate, anthropometric parameters

NCT04289701: Hypertension Registry of "Hypertension Prevention and Control Initiative in China"

Recruiting

N/A

200000

RoW

Health Services for Systematic Hypertension Management

Chinese Academy of Medical Sciences, Fuwai Hospital

Hypertension

12/22

12/24

NCT05357456: Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

Recruiting

N/A

RoW

Cognitive function assessment; functional magnetic resonance imaging, fMRI, laparoscopic adrenal surgery

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Autonomous Cortisol Secretion, Adrenal Incidentaloma, Non-functioning Adrenal Adenomas

10/24

10/26

Nedovic, Jasmina

NANORAY-312, NCT04892173 / 2021-002163-22: JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Recruiting

500

Europe, Japan, US, RoW

JNJ-90301900 (NBTXR3), Functionalized hafnium oxide nanoparticles, NBTXR3, Cetuximab, Erbitux, Radiation Therapy

Johnson & Johnson Enterprise Innovation Inc., Nanobiotix SA

Locally Advanced Head and Neck Squamous Cell Carcinoma, Aged

06/26

06/27

NCT04381650 / 2020-004325-23: A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

Active, not recruiting

1/2

Europe, Japan, US, RoW

TAK-981, Pembrolizumab

Takeda, Takeda Development Center Americas, Inc.

Advanced or Metastatic Solid Tumors

11/25

Zdravkovic-Petrovic, Natasa

LUCENT-3, NCT03519945 / 2017-004092-31: A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

Jan 2022 - Mar 2022 : Data from LUCENT 3 trial for moderate-to-severe ulcerative colitis

Recruiting

1063

Europe, Canada, Japan, US, RoW

Mirikizumab, LY3074828

Eli Lilly and Company

Ulcerative Colitis

07/26

12/27

Chen, Qinkai

NCT04381143: ASPIrin in Reducing Events in Dialysis ( ASPIRED )

Recruiting

9000

RoW

Aspirin 100 mg Oral Tablet, Matching Placebo

Guangdong Provincial People's Hospital, The George Institute

CKD (Chronic Kidney Disease) Stage 5D

09/26

12/26

ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting

404

Europe, Canada, Japan, US, RoW

Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo

Chinook Therapeutics, Inc.

IgA Nephropathy, Immunoglobulin A Nephropathy

12/26

NCT05136456: Evaluate the Efficacy and Safety of SHR1459 Tablets in Patients With Primary Membranous Nephropathy

Active, not recruiting

RoW

SHR1459 Low Dose, SHR1459 High Dose, Placebo

Reistone Biopharma Company Limited

Primary Membranous Nephropathy

08/23

03/24

NCT05810961: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Primary Membranous Nephropathy (ZL-1103-014)

Terminated

RoW

efgartigimod IV, placebo

argenx, Zai Lab Pty. Ltd.

Membranous Nephropathy

08/24

NCT05810948: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Lupus Nephritis (ZL-1103-013)

Active, not recruiting

RoW

efgartigimod IV, Placebo

argenx, Zai Lab (Shanghai) Co., Ltd.

Lupus Nephritis

07/25

09/25

PALIZADE, NCT05781750: A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis

Suspended

279

Europe, US, RoW

zetomipzomib, KZR-616, placebo, matching placebo

Kezar Life Sciences, Inc.

Lupus Nephritis

05/26

07/26

NCT05450523: Neutrophil Gelatinase-Associated Lipocalin (NGAL) Rapid Test (Colloidal Gold) Clinical Trial Protocol

Completed

N/A

220

RoW

Qingdao HIGHTOP Biotech Co., Ltd.

Peritoneal Dialysis-associated Peritonitis

09/22

Balaz, Jozef

ABX464-106, NCT05507216: ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

Recruiting

612

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

03/25

04/25

LUCENT-URGE, NCT05767021: A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis

Active, not recruiting

160

Europe, US, RoW

Mirikizumab, LY3074828

Eli Lilly and Company

Ulcerative Colitis, Ulcerative Colitis Chronic

08/24

09/25

VIVID-2, NCT04232553 / 2019-002687-27: A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

Recruiting

778

Europe, Canada, Japan, US, RoW

Mirikizumab, LY3074828

Eli Lilly and Company

Crohn's Disease

11/24

12/26

ABTECT, NCT05535946: - Maintenance

Recruiting

1050

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

01/26

01/30

LUCENT-3, NCT03519945 / 2017-004092-31: A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)

Jan 2022 - Mar 2022 : Data from LUCENT 3 trial for moderate-to-severe ulcerative colitis

Recruiting

1063

Europe, Canada, Japan, US, RoW

Mirikizumab, LY3074828

Eli Lilly and Company

Ulcerative Colitis

07/26

12/27

NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Recruiting

268

Europe, Canada, Japan, US, RoW

TAK-279, Zasocitinib, Placebo

Takeda

Crohn's Disease

09/26

07/27

NCT06254950: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Recruiting

207

Europe, Canada, Japan, US, RoW

TAK-279, Zasocitinib, Placebo

Takeda

Ulcerative Colitis

09/26

08/27

Contact, Site Public

NCT04985682 / 2022-004149-11: A Study of ADVATE in People With Hemophilia A in India

Completed

RoW

ADVATE

Baxalta now part of Shire, Takeda Development Center Americas, Inc.

Hemophilia A

02/23

SWITCH, NCT04718779: A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy

Completed

Digital Engagement Application (GD App), No Intervention

Takeda

Gaucher Disease

02/23

COMPASS-CD, NCT04809363: A Study of CDPATH™ to Help Manage and Treat Crohn's Disease

Active, not recruiting

200

CDPATH™, PROSPECT, Blood Draw

Takeda

Crohn's Disease

10/25

06/26

NCT05341115 / 2022-002471-11: A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty

Recruiting

RoW

Leuprorelin Acetate Depot 3M, Leuprolide acetate Depot 3M

Takeda, Takeda

Central Precocious Puberty

05/25

TAK-665-4001, NCT05058391 / 2022-004193-39: A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in India

Completed

RoW

Elaprase, Idursulfase

Takeda, Takeda Biopharmaceuticals India Pvt. Ltd.

Hunter Syndrome

04/24

NCT05442554: A Study of Brentuximab Vedotin Treatment in Chinese Adults With CD30-Positive Cutaneous T-Cell Lymphoma

Completed

RoW

Brentuximab vedotin, SGN-35

Takeda

T-Cell Lymphoma

08/24

NCT05067868: A Study of Replagal in Children and Adults With Fabry Disease in India

Active, not recruiting

RoW

Replagal

Shire

Fabry Disease

10/26

11/26

TAK-113-4002, NCT06562543: A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

Recruiting

Fruquintinib, Fruzaqla™

Takeda

Colorectal Cancer

02/28

NCT04085172 / 2018-000821-29: A Study of TAK-503 in Children and Teenagers With Attention Deficit Hyperactivity Disorder (ADHD)

Active, not recruiting

288

Europe, US

Guanfacine hydrochloride (TAK-503), Intuniv, SPD503, Atomoxetine hydrochloride, Placebo

Shire, Takeda Development Center Americas, Inc.

Attention Deficit Hyperactivity Disorder

06/27

ASPIRE, NCT04118088 / 2017-002491-10: A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula

Active, not recruiting

Europe, RoW

Darvadstrocel, Alofisel, Cx601

Takeda, Takeda Development Center Americas, Inc.

Crohn's Disease, Complex Perianal Fistula

03/26

NCT05494593: A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

Recruiting

ELAPRASE, Idursulfase, Rituximab, Methotrexate, Intravenous Immunoglobulin (IVIG)

Takeda, Takeda Development Center Americas, Inc.

Mucopolysaccharidosis (MPS), Hunter Syndrome

07/28

NCT06045754: A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Recruiting

150

Canada, US

Vedolizumab, Entyvio, Adalimumab, Humira, Ustekinumab, Stelara

Takeda

Crohn's Disease

06/27

NCT06095128: A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Recruiting

Canada, US

Vedolizumab, Entyvio, MLN0002, Tofacitinib, Xeljanz, CP-690, CP-550

Takeda

Ulcerative Colitis

07/27

PhALLCON, NCT03589326 / 2018-000397-30: A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

	Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Sep 2019 - Sep 2019: Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Initiation of new trial in Ph+ ALL
	Jul 2018 - Jul 2018: Initiation of new trial in Ph+ ALL

Active, not recruiting

245

Europe, Canada, Japan, US, RoW

Ponatinib, Iclusig, Imatinib, Gleevec, Vincristine, Dexamethasone, Cytarabine, Methotrexate, Prednisone

Takeda

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

08/22

07/27

NCT04840667 / 2018-004689-32: A Study of Replagal in Treatment-naïve Adults With Fabry Disease

Terminated

Europe, Canada

REPLAGAL, SHP675

Shire

Fabry Disease

12/22

NCT04444895 / 2019-004823-20: A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor

Completed

Europe, Canada, Japan, US

Lanadelumab, DX-2930, SHP643, TAK-743

Shire, Takeda Development Center Americas, Inc.

Angioedema

05/23

NCT03927027: Axillary Reverse Mapping in Preventing Lymphedema in Patients with Breast Cancer Undergoing Axillary Lymph Node Dissection

Active, not recruiting

534

Isosulfan Blue, Axillary Lymph Node Dissection, ALND, axillary dissection, Mapping, Quality-of-Life Assessment, Questionnaire Administration

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III

11/26

01/27

NRG-BR003, NCT02488967: Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

Active, not recruiting

782

Canada, US

Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplat, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR- 138719, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Laboratory Biomarker Analysis, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat

NRG Oncology, National Cancer Institute (NCI)

Breast Adenocarcinoma, Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor Negative, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage IIIA Breast Cancer, Stage IIIC Breast Cancer, Triple-Negative Breast Carcinoma

10/26

NCT03393975 / 2017-000858-18: A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Completed

Europe, Japan, US

BAX930, rADAMTS13, SHP-655, TAK-755, recombinant ADAMTS13, BAX 930, Standard of care

Baxalta now part of Shire, Takeda Development Center Americas, Inc.

Thrombotic Thrombocytopenic Purpura (TTP)

12/23

05/24

SWOG-S1600, NCT03757949: Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery

Active, not recruiting

203

Laboratory Biomarker Analysis, Nutritional Intervention, Placebo Administration, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration

SWOG Cancer Research Network, National Cancer Institute (NCI)

Bladder Carcinoma

01/24

01/27

NCT03550391: Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Recruiting

206

Canada, US

Memantine, Hippocampal-avoidant (HA-WBRT) Radiotherapy, Stereotactic Radiosurgery (SRS)

Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, NRG Oncology

Brain Metastases

06/27

12/27

NCT03879135 / 2018-003453-16: A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)

Active, not recruiting

Europe, US, RoW

rVWF, Vonvendi, Vonicog alfa, rFVIII, Octocog alfa, ADVATE

Baxalta now part of Shire, Takeda Development Center Americas, Inc.

Von Willebrand Disease (VWD)

03/25

EA2183, NCT04248452: Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Recruiting

314

Capecitabine, Ro 09-1978/000, Xeloda, Fluorouracil, 5 Fluorouracil, 5 Fluorouracilum, 5 FU, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-FU, 5FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Leucovorin, folinic acid, Leucovorin Calcium, Adinepar, Calcifolin, Calcium (6S)-Folinate, Calcium Folinate, Calcium Leucovorin, Calfolex, Calinat, Cehafolin, Citofolin, Citrec, Citrovorum Factor, Cromatonbic Folinico, Dalisol, Disintox, Divical, Ecofol, Emovis, Factor, Citrovorum, Flynoken A, Folaren, Folaxin, FOLI-cell, Foliben, Folidan, Folidar, Folinac, Folinate Calcium, Folinic Acid Calcium Salt Pentahydrate, Folinoral, Folinvit, Foliplus, Folix, Imo, Lederfolat, Lederfolin, Leucosar, leucovorin, Rescufolin, Rescuvolin, Tonofolin, Wellcovorin, Oxaliplatin, 1-OHP, Ai Heng, Aiheng, Dacotin, Dacplat, Diaminocyclohexane Oxalatoplatinum, Eloxatin, Eloxatine, JM-83, Oxalatoplatin, Oxalatoplatinum, RP 54780, RP-54780, SR-96669, Radiation Therapy, Cancer Radiotherapy, Irradiate, irradiated, Irradiation, RADIATION, Radiation Therapy, NOS, Radiotherapeutics, RADIOTHERAPY, RT, Therapy, Radiation

ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)

Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Metastatic Esophageal Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Oligometastatic Esophageal Adenocarcinoma, Oligometastatic Gastric Adenocarcinoma, Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IV Gastric Cancer AJCC v8, Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8

03/28

NCT03941860: Testing the Addition of Ixazomib/Placebo to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial

Active, not recruiting

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspirate, BONE MARROW, LIQUID, Human Bone Marrow Aspirate, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Ixazomib Citrate, MLN 9708, MLN-9708, MLN9708, Ninlaro, Lenalidomide, CC 5013, CC-5013, CC5013, CDC 501, Revlimid, Placebo Administration, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration

National Cancer Institute (NCI)

Multiple Myeloma

08/23

04/25

SOLARIS, NCT04094688: Vitamin D3 with Chemotherapy and Bevacizumab in Treating Patients with Advanced or Metastatic Colorectal Cancer

Active, not recruiting

455

Bevacizumab, Oxaliplatin, Leucovorin Calcium, Fluorouracil, Irinotecan Hydrochloride, Irinotecan, Cholecalciferol, Vitamin D3, Quality-of-Life Assessment, Questionnaire Administration

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Colorectal Adenocarcinoma

01/26

07/26

SKYWAY, NCT04938427 / 2021-002481-40: A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

Completed

270

Europe, Canada, Japan, US, RoW

Placebo, Soticlestat, TAK-935

Takeda

Lennox Gastaut Syndrome (LGS)

01/24

NCT06165341: Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Recruiting

Europe, Canada, US

Fazirsiran Injection, TAK-999, ARO-AAT, ADS-001, Placebo

Takeda

Alpha1-Antitrypsin Deficiency

08/28

NCT02932618 / 2016-001477-33: A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

Recruiting

Europe, US, RoW

von Willebrand factor (Recombinant), VONVENDI, rVWF, BAX111, BAX 111, Antihemophilic Factor (Recombinant), ADVATE, Recombinant Factor VIII, rFVIII

Baxalta now part of Shire, Takeda Development Center Americas, Inc.

Von Willebrand Disease

01/25

NCT04939090: Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Recruiting

360

Olanzapine, Megestrol Acetate, Questionnaire Administration

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Advanced Malignant Solid Neoplasm, Anorexia, Hematopoietic and Lymphoid Cell Neoplasm

05/26

12/26

SKYLINE, NCT04940624 / 2021-002480-22: A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Completed

144

Europe, Canada, Japan, US, RoW

Soticlestat, TAK-935, Placebo

Takeda

Dravet Syndrome (DS)

04/24

NCT06172296: Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting

478

Canada, US, RoW

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Asta B 518, B 518, B-518, B518, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR 138719, WR- 138719, WR-138719, WR138719, Dinutuximab, Ch 14.18UTC, Ch14.18, Dinutuximab Beta, MOAB Ch14.18, monoclonal antibody Ch14.18, Qarziba, Unituxin, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP 16213, VP-16, VP-16-213, VP-16213, VP16, VP16213, FDG-Positron Emission Tomography and Computed Tomography Scan, FDG PET/CT, Hematopoietic Cell Transplantation, HCT, Hematopoietic Stem Cell Infusion, HEMATOPOIETIC STEM CELL TRANSPLANT, Hematopoietic Stem Cell Transplantation, HSCT, SCT, Stem Cell Transplant, stem cell transplantation, Stem Cell Transplantation, NOS, Irinotecan, Isotretinoin, 13-cis retinoic acid, 13-cis-Retinoate, 13-cis-Retinoic Acid, 13-cis-Vitamin A Acid, 13-cRA, Absorica, Accure, Accutane, Amnesteem, cis-Retinoic Acid, Cistane, Claravis, Isotretinoinum, Isotrex, Isotrexin, Myorisan, Neovitamin A, Neovitamin A Acid, Oratane, Retinoicacid-13-cis, Ro 4-3780, Ro-4-3780, Roaccutan, Roaccutane, Roacutan, Sotret, ZENATANE, Leukapheresis, Leukocyte Adsorptive Apheresis, Leukocytopheresis, Therapeutic Leukopheresis, White Blood Cell Reduction Apheresis, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Melphalan, Alanine Nitrogen Mustard, CB-3025, L-PAM, L-Phenylalanine Mustard, L-Sarcolysin, L-Sarcolysin Phenylalanine mustard, L-Sarcolysine, Melphalan for Injection-Hepatic Delivery System, Melphalanum, Phenylalanine Mustard, Phenylalanine Nitrogen Mustard, Sarcoclorin, Sarkolysin, WR-19813, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation, Radionuclide Imaging, NM, Nuclear Medicine, nuclear medicine scan, radioimaging, Radionuclide Scanning, Scan, Scintigraphy, Survey Administration, Temozolomide, CCRG-81045, Gliotem, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temizole, Temodal, Temodar, Temomedac, TMZ, Thiotepa, 1,1',1''-Phosphinothioylidynetrisaziridine, Girostan, N,N', N''-Triethylenethiophosphoramide, Oncotiotepa, SH 105, SH-105, SH105, STEPA, Tepadina, Tepylute, TESPA, Tespamin, Tespamine, Thio-Tepa, Thiofosfamide, Thiofozil, Thiophosphamide, Thiophosphoamide, Thiophosphoramide, Thiotef, Tifosyl, TIO TEF, Tio-tef, Triethylene Thiophosphoramide, Triethylenethiophosphoramide, Tris(1-aziridinyl)phosphine sulfide, TSPA, WR 45312, Topotecan, Hycamptamine, Topotecan Lactone, Tumor Resection, Vincristine, LCR, Leurocristine, VCR, Vincrystine

National Cancer Institute (NCI)

Ganglioneuroblastoma, Nodular, Neuroblastoma

12/29

ASCENDE-SBRT, NCT06235697: Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

Recruiting

710

Canada, US

Radiation, Radiation SBRT only, ADT, Androgen Deprivation Therapy

Canadian Cancer Trials Group, NRG Oncology

Prostate Cancer

10/32

04/33

TAK-935-3004, NCT06422377: A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Terminated

Europe

Soticlestat, TAK-935

Takeda

Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS)

08/24

CASPAR, NCT04455750: A Clinical Study Evaluating the Benefit of Adding Rucaparib to Enzalutamide for Men with Metastatic Prostate Cancer That Has Become Resistant to Testosterone-Deprivation Therapy

Active, not recruiting

Enzalutamide, Rucaparib camsylate, Placebo, Leuprolide Acetate, Goserelin Acetate, Degarelix, Quality-of-Life Assessment, Questionnaire Administration

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)

Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC V8, Stage IVA Prostate Cancer AJCC V8, Stage IVB Prostate Cancer AJCC V8

03/26

09/27

NCT04974749 / 2022-004246-35: A Study of REPLAGAL® in Treatment-naive Chinese Participants With Fabry Disease

Completed

RoW

REPLAGAL, Agalsidase Alfa, TAK-675

Takeda, Takeda Development Center Americas, Inc

Fabry Disease

01/24

NCT02375204: Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors

Active, not recruiting

420

Europe, US, RoW

paclitaxel, Taxol, ifosfamide, Ifex®, IFOS, cisplatin, CDDP, pegylated G-CSF, G-CSF, carboplatin, Paraplatin®, CBDCA, etoposide phosphate, VePesid®, Toposar®, VP16, stem cell reinfusion

Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI), European Organisation for Research and Treatment of Cancer - EORTC, Movember Foundation, Institute of Cancer Research (ICR), United Kingdom, Cancer Research UK, UNICANCER, Irish Group CTI

Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma, Mixed Germ Cell Tumor, Yolk Sac Tumor, Childhood Teratoma, Malignant Germ Cell Neoplasm, Extragonadal Seminoma, Non-seminomatous Germ Cell Tumor, Seminoma

06/31

NCT05460325 / 2023-001105-31: A Study of Lanadelumab (SHP643) in Chinese Participants With Hereditary Angioedema (HAE)

Completed

RoW

Lanadelumab, SHP643, TAKHZYRO, TAK-743, DX-2930, Lanadelumab Injection

Takeda, Takeda

Hereditary Angioedema (HAE)

11/23

NEO-RT, NCT06205485: Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Recruiting

250

Canada, US

Leucovorin, Oxaliplatin, Fluoruracil, Capecitabine, Radiation

Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, ECOG-ACRIN Cancer Research Group, NRG Oncology, SWOG Cancer Research Network

Rectal Cancer

01/30

06/30

NRG-GI003, NCT03186898: Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

Recruiting

186

Proton Therapy (Radiation Therapy), Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RADIATION, Radiation Therapy, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation, Photon Therapy (Radiation Therapy)

NRG Oncology, National Cancer Institute (NCI)

Unrectable or Locally Recurrent Hepatocellular Carcinoma

06/27

06/29

NCT06475989: Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Recruiting

264

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cabozantinib, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Dabrafenib, BRAF Inhibitor GSK2118436, GSK-2118436, GSK-2118436A, GSK2118436, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Questionnaire Administration, Trametinib, GSK 1120212, GSK-1120212, GSK1120212, JTP-74057, MEK Inhibitor GSK1120212

ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)

Refractory Differentiated Thyroid Gland Carcinoma

09/30

NRG-BN013, NCT06500455: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Recruiting

269

Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fractionated Stereotactic Radiation Therapy, Fractionated Stereotactic Radiotherapy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Stereotactic Radiosurgery, SRS, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery

NRG Oncology, National Cancer Institute (NCI)

Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8

06/28

06/33



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