| Anton, Stephen D |
| Recruiting | 4 | 20000 | US | Atorvastatin 40 Mg Oral Tablet, Lipitor, Placebo oral tablet | Duke University, National Institute on Aging (NIA), National Heart, Lung, and Blood Institute (NHLBI), Wake Forest University Health Sciences | Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases | 12/26 | 12/26 | | |
| Recruiting | 2 | 40 | US | Krill oil, Mixed vegetable oil | University of Florida, National Institute on Aging (NIA) | Chronic Musculoskeletal Pain | 01/26 | 03/26 | | |
NCT05568511: Home-based Digital Exercise Training Program to Improve Physical Function of Older Sepsis Survivors - HEAL Sepsis Trial |
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| Recruiting | N/A | 40 | US | App-based exercise program, Standard of Care | University of Florida, National Institute on Aging (NIA) | Exercise Program, Standard Care Control | 12/24 | 12/24 | | |
| Recruiting | N/A | 52 | US | Time Restricted Eating intervention, TRE intervention, Successful Aging Comparison Group (LEARN) | University of Florida, Florida Department of Health, Ed and Ethel Moore Alzheimer's Disease Research Program | Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease | 08/25 | 08/25 | | |
| Recruiting | N/A | 24 | US | Center-Based Walking Exercise, Home-Based Walking Exercise | University of Florida | Fatigue, Breast Cancer, Cancer, Therapy-Related | 08/25 | 08/25 | | |
| Completed | N/A | 197 | US | Bariatric Surgery Candidates, Non surgical/Community volunteers | University of Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Diabetes, Weightloss | 11/22 | 11/22 | | |
| Recruiting | N/A | 15 | US | Time Restricted Eating Intervention | University of Florida, National Institute on Aging (NIA) | Aging | 12/25 | 03/26 | | |
| Clark, David G |
| Completed | 2b | 353 | Europe, US | Nalbuphine ER Tablets, NAL ER Tablets, Matching Placebo Tablets | Trevi Therapeutics | Prurigo Nodularis | 05/22 | 02/23 | | |
| Active, not recruiting | 2 | 60 | Europe, Canada | Nalbuphine ER, Active, Placebo | Trevi Therapeutics | Refractory Chronic Cough | 01/25 | 01/25 | | |
| Recruiting | 2 | 160 | Europe, Canada, RoW | nalbuphine ER 27 mg, Active, Placebo, nalbuphine ER 54 mg, nalbuphine ER 108 mg | Trevi Therapeutics | Idiopathic Pulmonary Fibrosis | 04/25 | 04/25 | | |
| Completed | 1 | 100 | US | practice of a complex walking task, Dosage A: transcranial direct current stimulation (tDCS), Dosage B: transcranial direct current stimulation (tDCS) | VA Office of Research and Development | Aging | 08/24 | 08/24 | | |
NCT03504826: Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics |
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| Active, not recruiting | N/A | 21 | US | Hybrid Assistive Limb (HAL) | Brooks Rehabilitation, University of Florida | Spinal Cord Injuries | 07/24 | 12/24 | | |
| Recruiting | N/A | 850 | Europe, US, RoW | Flortaucipir, 18F-AV-1451 (also known as [F-18]T807 or LY3191748), Florbetaben, AV-45, Neuraceq, Fluorodeoxyglucose, FDG | Indiana University, Alzheimer's Therapeutic Research Institute, National Institute on Aging (NIA), Alzheimer's Association | Early Onset Alzheimer Disease, Alzheimer Disease, Mild Cognitive Impairment | 05/25 | 05/25 | | |
NCT03737760: "Mind in Motion": Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults |
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| Active, not recruiting | N/A | 270 | US | | University of Florida, National Institute on Aging (NIA) | Effect of Age-related Changes in the Brain on Walking Ability | 05/25 | 05/25 | | |
NCT04363684: ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) |
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| Recruiting | N/A | 2100 | Canada, US | | Mayo Clinic, University of California, San Francisco, National Institute on Aging (NIA), National Institute of Neurological Disorders and Stroke (NINDS) | Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Behavioral Variant Frontotemporal Dementia (bvFTD), Semantic Variant Primary Progressive Aphasia (svPPA), Nonfluent Variant Primary Progressive Aphasia (nfvPPA), FTD With Amyotrophic Lateral Sclerosis (FTD/ALS), Amyotrophic Lateral Sclerosis, Oligosymptomatic PSP (oPSP), C9orf72, GRN Related Frontotemporal Dementia, MAPT Gene Mutation, TBK1 Gene Mutation, Oligosymptomatic Progressive Supranuclear Palsy | 06/25 | 06/25 | | |
| Recruiting | N/A | 2529 | US | Pain EASE, Tailored exercise, Continued Care and Active Monitoring, Cognitive Behavioral Therapy (CBT), Spinal Manipulation Therapy (SMT), Yoga | VA Office of Research and Development | Chronic Low Back Pain | 06/25 | 06/26 | | |
| Recruiting | N/A | 70 | US | Complex Balance Tasks | VA Office of Research and Development | Traumatic Brain Injury | 06/25 | 06/25 | | |
NCT05830942: Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults |
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| Recruiting | N/A | 120 | US | Walking Exercise, Prefrontal Active tDCS, Prefrontal Sham tDCS | University of Florida, National Institute on Aging (NIA) | Cognitive Dysfunction, Mobility Limitation, Frail Elderly | 04/27 | 04/27 | | |
| Active, not recruiting | N/A | 73 | Europe | AS Domelock System | Zimmer Biomet | Avascular Necrosis, Revision Surgery, Conditions Consequent to Earlier Operations, Arthritis, Rheumatoid, Arthritis, Degenerative, Arthritis;Traumatic | 12/32 | 12/32 | | |
| Buford, Thomas W |
| Completed | 2 | 223 | US | Aerobic exercise, Perindopril, Losartan, HCTZ | University of Alabama at Birmingham, University of Colorado, Denver, AdventHealth Translational Research Institute | Hypertension, Aging, Sedentary Lifestyle | 09/24 | 09/24 | | |
| Manini, Todd M |
NCT03573583: Time Course Adaptations Using Deuterated Creatine (D3Cr) Method |
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| Completed | N/A | 21 | US | Resistance Training, RT, Strength Training, Weight Training, Successful Aging, HE, Health Education | University of Florida, National Institute on Aging (NIA) | Sarcopenia | 08/20 | 08/20 | | |
STRONGER, NCT05721898: Assessment of Cortical Bone Mechanics Technology (CBMT) Fracture Discrimination Capability |
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| Completed | N/A | 394 | US | Cortical Bone Mechanics Technology | Ohio University, Indiana University School of Medicine, University of Florida, University of South Florida | Osteoporosis, Osteopenia or Osteoporosis, Osteoporosis, Postmenopausal, Osteoporosis Risk, Osteoporotic Fractures, Fragility Fracture, Bone Fracture | 10/23 | 10/23 | | |
| Recruiting | N/A | 50 | US | Actionable remotely generated health data, Non-Actionable remotely generated health data | University of Florida, National Institute on Aging (NIA) | Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | 10/26 | 10/26 | | |
| Woods, Adam J |
| Recruiting | 3 | 7600 | US | Cognitive Training, Computerized Cognitive Stimulation | University of South Florida, National Institute on Aging (NIA) | Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias | 01/26 | 01/26 | | |
NCT04018092: The Revitalize Study in Older Adults at Risk for Alzheimer's Disease |
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| Recruiting | 2 | 168 | US | Active NIR-PBM, Sham NIR-PBM | University of Florida, University of Arizona, National Institute on Aging (NIA) | Cognitive Aging, Alzheimer Disease, Protection Against | 04/25 | 04/25 | | |
| Completed | N/A | 379 | US | Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation), Educational Training | University of Florida, University of Arizona, National Institute on Aging (NIA) | Aging | 04/22 | 04/22 | | |
NCT05377411: SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults |
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| Completed | N/A | 33 | US | tDCS, cognitive training | University of Florida, Soterix Medical | Aging | 06/24 | 06/24 | | |
NCT03551392: Pilot Intervention With Near Infrared Stimulation |
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| Recruiting | N/A | 24 | US | Medx Console System, Low Level Light Therapy, Photobiomodulation, Transcranial Near Infrared Stimulation, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit | University of Florida, McKnight Brain Research Foundation, University of Arizona | Aging | 04/26 | 04/26 | | |
| Completed | N/A | 197 | US | Bariatric Surgery Candidates, Non surgical/Community volunteers | University of Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Diabetes, Weightloss | 11/22 | 11/22 | | |
| Recruiting | N/A | 1305 | US | Cognitive Training, Computerized Cognitive Stimulation | University of Alabama at Birmingham, University of Florida, University of Minnesota, National Institute on Aging (NIA), Clemson University, University of California, San Francisco | Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia | 08/27 | 08/27 | | |
