Walter Reed Project - Kenya Med. Research Institute Kericho CRS (12501)
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 5 Trials 
9 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Sawe, Fredrick
GlycoShig3, NCT04602975: A Study to Investigate the Safety and Immunogenicity of the SF2a-TT15 Synthetic Carbohydrate-based Conjugate Vaccine Against Shigella Flexneri 2a

Completed
2
248
RoW
Injection SF2A-TT15 10 µg Adjuvanted, SF2A-TT15 10 µg Adjuvanted, Anti-shigella experimental vaccine (10µg with alhydrogel), Injection SF2A-TT15 10 µg, SF2A-TT15 10 µg not adjuvanted, Anti-shigella experimental vaccine (10µg without alhydrogel), Injection Adjuvanted Placebo, Placebo with Alhydrogel injection, Injection Placebo, Placebo without alhydrogel injection, Injection SF2A-TT15 2 µg Adjuvanted, SF2A-TT15 2 µg Adjuvanted, Anti-shigella experimental vaccine (2µg with alhydrogel), Injection SF2A-TT15 2 µg, SF2A-TT15 2 µg not adjuvanted, Anti-shigella experimental vaccine (2µg without alhydrogel)
Institut Pasteur, Wellcome Trust, Bill & Melinda Gates Medical Research Institute, Henry M. Jackson Foundation Medical Research International, Walter Reed Army Institute of Research (WRAIR), Parexel, ClinWin Research
Healthy
04/23
11/23
NCT05073003 / 2021-000891-12: A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants

Recruiting
1/2
550
Europe, RoW
altSonflex Placebo, altSonflex1-2-3 Dose C, Shigella vaccine, altSonflex1-2-3 Dose B, altSonflex1-2-3 Dose A, GSK's Meningococcal A, C, Y and W-135 conjugate vaccine, MENVEO, GSK's Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine, BOOSTRIX, GSK's Diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis (inactivated), and Haemophilus influenzae type b vaccine, INFANRIX Hexa, Sanofi Pasteur's Typhoid Vi polysaccharide vaccine, TYPHIM VI, Serum Institute of India's Measles and rubella vaccine, MR-VAC
GlaxoSmithKline
Diarrhoea
06/25
06/25
Chirchir, Samwel K
BEe-HIVe, NCT04193189: B-Enhancement of HBV Vaccination in Persons Living With HIV (): Evaluation of HEPLISAV-B

Completed
3
640
US, RoW
HEPLISAV-B, ENGERIX-B
National Institute of Allergy and Infectious Diseases (NIAID), Dynavax Technologies Corporation
HIV Infection, Hepatitis B
08/24
08/24
PHOENIx MDR-TB, NCT03568383: Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients

Recruiting
3
5610
RoW
Delamanid (DLM), Isoniazid (INH), Pyridoxine (vitamin B6)
National Institute of Allergy and Infectious Diseases (NIAID), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Otsuka Pharmaceutical Development & Commercialization, Inc.
Tuberculosis, MDR
07/27
07/27
RAD-TB, NCT06192160: Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis

Not yet recruiting
2
315
RoW
Isoniazid, INH, Rifampicin, RIF, Pyrazinamide, PZA, Ethambutol, EMB, Bedaquiline, BDQ, Pretomanid, Pa, Linezolid, LZD, TBI-223, Sutezolid, SZD
National Institute of Allergy and Infectious Diseases (NIAID), TB Alliance
Pulmonary Tuberculosis
03/26
03/27
NCT06705478: Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Not yet recruiting
2
186
US, RoW
Pramipexole ER, Escitalopram
National Institute of Allergy and Infectious Diseases (NIAID), Cipla Ltd.
Major Depressive Disorder, Mild Neurocognitive Disorder, HIV
12/26
12/26
NCT05383742: Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Recruiting
2
330
RoW
Rifampicin (RIF), Isoniazid (INH), Linezolid (LZD), Pyrazinamide (PZA), ethambutol (EMB), Rifampicin, Isoniazid
National Institute of Allergy and Infectious Diseases (NIAID)
Tuberculous Meningitis
05/27
05/27
NCT02140255: Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

Recruiting
1/2
1120
US, RoW
Nucleoside Reverse Transcriptase Inhibitors (NRTIs), Nevirapine (NVP), Lopinavir/Ritonavir (LPV/r), Raltegravir (RAL), VRC01, DTG, VRC07-523LS
National Institute of Allergy and Infectious Diseases (NIAID), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Mental Health (NIMH)
HIV Infection
01/28
12/31
NCT04518228: Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Recruiting
N/A
325
US, RoW
Bictegravir (BIC), Tenofovir alafenamide (TAF), Cabotegravir (CAB), Dolutegravir (DTG), Atazanavir/ritonavir (ATV/r), Darunavir/ritonavir (DRV/r), Lopinavir/ritonavir (LPV/r), Cobicistat, Ritonavir, First-Line TB Treatment, Second-Line TB Treatment, Doravirine (DOR)
National Institute of Allergy and Infectious Diseases (NIAID), International Maternal Pediatric Adolescent AIDS Clinical Trials Group, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Mental Health (NIMH), Gilead Sciences, ViiV Healthcare, Merck Sharp & Dohme LLC
HIV Infections, Tuberculosis
03/26
03/26
Ngeno, Hellen
No trials found

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