Kutyifa, Valentina |
| Completed | N/A | 360 | Europe, RoW | CRT-D | Semmelweis University Heart and Vascular Center, University of Rochester, Sheba Medical Center, Pharmahungary Group | Cardiomyopathy | 08/22 | 08/22 | | |
MADIT S-ICD, NCT02787785: Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator |
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| Completed | N/A | 40 | Europe, US, RoW | Subcutaneous Implantable Cardioverter Defibrillator | Boston Scientific Corporation, University of Rochester | Tachycardia, Diabetes Mellitus, Cardiovascular Disease | 06/23 | 06/23 | | |
| Recruiting | N/A | 300 | US | Heart Rate Monitor Enhanced Treatment Optimization, LifeVest Wearable Cardioverter Defibrillator | Zoll Medical Corporation | Cardiomyopathies, Heart Failure | 09/24 | 12/24 | | |
BIO-LIBRA, NCT03884608: Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy |
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| Completed | N/A | 1000 | US | | Biotronik, Inc., University of Rochester | Cardiomyopathies, Gender, Implantable Defibrillator User | 11/24 | 11/24 | | |
A-SPIRE-HF, NCT04550052: A-SPIRE Heart Failure: Utilizing Health Tags to Identify Patients at Risk for Hospital Readmissions |
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| Active, not recruiting | N/A | 36 | US | | University of Rochester, Spire, Inc. | Heart Failure | 12/26 | 12/26 | | |
Sayfo, Sameh |
| Completed | N/A | 133 | US | AngioSafe Peripheral CTO Crossing System | AngioSafe, Inc., Veranex, Inc. | Peripheral Artery Occlusion, Peripheral Arterial Disease | 04/23 | 06/23 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Active, not recruiting | N/A | 75 | US | Misago® RX Self-expanding Peripheral Stent | Terumo Medical Corporation | Iliac Artery Stenosis | 03/25 | 09/26 | | |
| Recruiting | N/A | 200 | US, RoW | Esprit BTK System | Abbott Medical Devices | Chronic Limb-Threatening Ischemia | 04/27 | 05/29 | | |
| Recruiting | N/A | 300 | Europe, US, RoW | SELUTION SLR™ 018 DEB, Plain (Uncoated) Balloon Angioplasty (PTA) | MedAlliance, LLC, NAMSA, Cordis Corporation | Peripheral Arterial Disease, Superficial Femoral Artery Stenosis | 08/25 | 12/29 | | |
NCT06062329: SYMPHONY-PE Study for Treatment of Pulmonary Embolism |
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| Recruiting | N/A | 150 | US | Symphony Thrombectomy System | Imperative Care, Inc. | Acute Pulmonary Embolism, Thromboembolism, Emboli, Pulmonary, Thrombosis, Thrombus; Embolism, Embolism, Cardiovascular Diseases, Vascular Diseases | 03/25 | 04/25 | | |
NCT05677100: Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure |
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| Recruiting | N/A | 268 | US | Aortix System, Aortix Pump | Procyrion | Heart Failure, Cardiorenal Syndrome, Cardio-Renal Syndrome, ADHF, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure; With Decompensation, Heart Failure, Congestive | 07/25 | 12/25 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
| Recruiting | N/A | 1200 | Europe, Canada, US | FlowTriever System, Anticoagulation Agents | Inari Medical | Pulmonary Embolism | 07/26 | 07/26 | | |
Abo-Auda |
| Recruiting | N/A | 300 | US | Heart Rate Monitor Enhanced Treatment Optimization, LifeVest Wearable Cardioverter Defibrillator | Zoll Medical Corporation | Cardiomyopathies, Heart Failure | 09/24 | 12/24 | | |
Salazar, Robert |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
Salazar |
NCT05603832: A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement |
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| Active, not recruiting | 3 | 151 | US | F14, 0.25 % Bupivacaine HCl, Acetaminophen, Methocarbamol | Arthritis Innovation Corporation, Allucent | Post Operative Pain | 11/23 | 08/24 | | |
| Recruiting | N/A | 300 | US | Heart Rate Monitor Enhanced Treatment Optimization, LifeVest Wearable Cardioverter Defibrillator | Zoll Medical Corporation | Cardiomyopathies, Heart Failure | 09/24 | 12/24 | | |
Thukral, Nandish |
| Enrolling by invitation | N/A | 556 | US | Impella ECP | Abiomed Inc. | High-Risk Percutaneous Coronary Intervention | 12/25 | 12/26 | | |
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial |
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| Active, not recruiting | N/A | 527 | Europe, Canada, US | Impella CP® placement prior to reperfusion with Primary PCI | Abiomed Inc. | ST Elevation (STEMI) Myocardial Infarction of Anterior Wall | 09/24 | 10/30 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
Lavigne, Paul |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |