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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Nierenberg, Andrew A
MBD, NCT03395392: NRX-101 for Bipolar Depression With Subacute Suicidal Ideation	Completed	2/3	74	US	NRX-101, Lurasidone HCl, Latuda	NeuroRx, Inc., Prevail Infoworks, Inc	Bipolar Depression, Suicidal Ideation and Behavior	02/24	03/24
NCT02481245: BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study	Recruiting	2	30	US	Bezafibrate, Bezalip	Massachusetts General Hospital, Brain & Behavior Research Foundation, J Willard and Alice S. Marriott Foundation	Bipolar Disorder, Depressive Episode	02/23	06/23
NCT03748446: Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder	Recruiting	1	20	US	Xenon, Nitrogen gas	Massachusetts General Hospital	Major Depressive Disorder, Bipolar Depression	09/24	12/24
Eikermann, Matthias
NCT04092894: Suvorexant and Sleep/Delirium in ICU Patients	Recruiting	4	120	US	Suvorexant 20 mg, Belsomra, Placebo oral tablet, Placebo	Beth Israel Deaconess Medical Center, Merck Sharp & Dohme LLC	Insomnia, Sleep Fragmentation, Sleep Initiation and Maintenance Disorders, Postoperative Delirium	12/24	07/25
PANDORA, NCT04093219: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients	Recruiting	3	900	US	IV acetaminophen, ofirmev, Placebo	Beth Israel Deaconess Medical Center, National Institute on Aging (NIA)	Delirium in Old Age, Delirium, Coronary Artery Disease	01/25	01/26
MINDDS II, NCT06192615: Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep	Recruiting	3	1800	US	Intravenous Dexmedetomidine, Intravenous Precedex, Sublingual Dexmedetomidine, Sublingual Precedex, Intravenous Placebo, Placebo, Sublingual Placebo	Massachusetts General Hospital	Delirium	10/27	03/29
NCT01969227: The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures	Completed	N/A	15	US	Subanesthetic ketamine	Massachusetts General Hospital, Beth Israel Deaconess Medical Center	Mechanical Ventilation, Airway Patency, Respiratory Depression	12/22	12/22
Kamdar, Mihir
NCT06001749: Psilocybin in Cancer Pain Study	Recruiting	2	15	US	Psilocybin	Yvan Beaussant, MD, MSci, Cy Biopharma, Pancreatic Cancer North America	Opioid-Related Disorders, Pain Management, Pain Management and Care, Advanced Cancer, Advanced Cancers	12/25	12/26
Meyer, Matthew
NCT04836702: Echocardiography as Risk-Assessment for Major Adverse Cardiac Events in Major Vascular Surgery Patients	Completed	N/A	813	NA		University of Virginia	Left-Sided Heart Failure, Right-Sided Heart Failure, Heart Valve Diseases	06/20	03/22