| Kereiakes, Dean |
NCT02806570: The CorCinch - Functional Mitral Valve Regurgitation (FMR) Study |
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| Completed | N/A | 35 | US | Mitral valve repair | Ancora Heart, Inc. | Heart Failure, Mitral Valve Insufficiency, Cardiomyopathies | 01/20 | 08/24 | | |
NCT03168776: PIONEER III Trial to Assess Safety and Efficacy of the BuMA Supreme™ Drug Coated Coronary Stent in Patients With Coronary Disease |
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| Active, not recruiting | N/A | 1632 | Europe, Canada, Japan, US | BuMA Supreme DES, Xience or Promus DES | Sino Medical Sciences Technology Inc., Nova Vascular LLC | Coronary Artery Disease | 10/20 | 09/24 | | |
NCT02799823: Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial |
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| Terminated | N/A | 11 | US | HLT Transcatheter Aortic Valve System | HLT Inc. | Aortic Valve Stenosis | 01/23 | 01/23 | | |
| Withdrawn | N/A | 10 | US | The HLT® Meridian® TAVR Valve (Meridian® with TriVentTM Anticalcification Treatment Valve and Pathfinder® Delivery System) | HLT Inc. | Aortic Regurgitation | 01/23 | 01/23 | | |
CRYSTAL, NCT03423511: Trial to Demonstrate the Safety and Effectiveness of the MiStent II for the Revascularization of Coronary Arteries. |
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| Not yet recruiting | N/A | 1300 | NA | MiStent II coronary artery stent, Xience or Promus coronary artery stents | Micell Technologies, Baim Institute for Clinical Research, North American Science Associates Inc., Yale Cardiovascular Research Group | Coronary Artery Disease | 06/23 | 06/27 | | |
| Active, not recruiting | N/A | 25 | US | J-Valve TF System | JC Medical, Inc. | Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation | 07/24 | 08/29 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
NCT05966662: Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO) |
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| Active, not recruiting | N/A | 145 | US | IVL with Shockwave C2+ 2Hz Coronary IVL Catheter | Shockwave Medical, Inc. | Coronary Artery Disease, Myocardial Infarction | 01/25 | 12/25 | | |
| Recruiting | N/A | 194 | US | J-Valve Transfemoral (TF) System | JC Medical, Inc., Bright Research Partners, Minneapolis Heart Institute Foundation, Cardiovascular Research Foundation, New York | Aortic Valve Regurgitation, Aortic Valve Disease Mixed | 09/27 | 09/31 | | |
NCT04496518: Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) |
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| Active, not recruiting | N/A | 2200 | Europe, US | Intrinsic Antitachycardia Pacing (iATP) Therapy | Medtronic | Ventricular Tachycardia | 01/25 | 01/27 | | |
NCT04489225: Personalized Therapy Study - HFRS (TriageHF) Post Approval Study |
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| Active, not recruiting | N/A | 2200 | Europe, US | Observational | Medtronic | Heart Failure | 01/25 | 01/27 | | |
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR |
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| Recruiting | N/A | 300 | Europe, US | Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication | Cardiac Dimensions, Inc. | Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases | 12/26 | 12/30 | | |
ASQ, NCT04024943: Personalized Therapy Study - Attain Stability Quad Post-Approval Study |
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| Active, not recruiting | N/A | 1092 | Europe, US | Quadripolar LV Lead, Medtronic CRT-P, Medtronic CRT-D | Medtronic | Heart Failure | 01/27 | 04/27 | | |
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry |
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| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | Defibrillation using EV-ICD | Medtronic | Ventricular Arrhythmia, Tachycardia | 05/30 | 10/37 | | |
| Koncar, Igor |
| Active, not recruiting | N/A | 320 | RoW | high-sensitive troponin | University of Belgrade | Carotid Artery Stenosis | 10/23 | 10/25 | | |
VASCULAIDRETRO, NCT06206369: Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression |
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| Recruiting | N/A | 11000 | Europe, RoW | No intervention, retrospective study | Amsterdam UMC, location VUmc, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Technical University of Twente, Universidade do Porto, Centre Hospitalier Universitaire de Nice, Stichting Allai, Faculty of Medicine, University of Belgrade, Brightfish Be, Hospital District of Helsinki and Uusimaa, University of Bergen, Asklepios Kliniken Hamburg GmbH, University of Oxford, VINČA INSTITUTE OF NUCLEAR SCIENCES Belgrado | Aneurysm Abdominal, Peripheral Arterial Disease | 05/29 | 05/29 | | |
| Not yet recruiting | N/A | 80 | RoW | Intra-Operative Positioning System (IOPS), Conventional group | Clinical Centre of Serbia, Centerline Biomedical, Inc. | Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Radiation Exposure | 05/25 | 07/25 | | |
| Recruiting | N/A | 50 | RoW | carbohydrate-rich beverage, the experimental group | University of Belgrade | Abdominal Aortic Aneurysm, Leriche Syndrome | 05/25 | 05/25 | | |
| Banovic, Marko |
CLEAR-HF, NCT06689553: Percutaneously Delivered Automated Continual Fluid Removal System in Patients with Advanced Diuretic-Resistant Heart Failure |
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| Not yet recruiting | N/A | 8 | RoW | Automated Continual Fluid Removal System | Paragate Medical LTD | Heart Failure | 11/25 | 02/26 | | |
ELEANOR, NCT05438862: Early Aortic vaLve surgEry Versus wAtchful waitiNg Strategy in Severe Asymptomatic aOrtic reguRgitation |
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| Recruiting | N/A | 217 | Europe, RoW | State of art aortic valve surgery | Na Homolce Hospital, University Hospital Hradec Kralove, Centre of Cardiovascular and Transplantation Surgery, Czech Republic, St. Anne's University Hospital Brno, Czech Republic, VZW Cardiovascular Research Center Aalst, General University Hospital, Prague, University Clinical Centre of Republic of Srpska | Aortic Valve Regurgitation | 12/26 | 12/27 | | |
| Puri, Rishi |
| Available | N/A | | US | Revivent TC System | BioVentrix | Heart Failure, Left Ventricle Remodeling | | | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Recruiting | N/A | 15 | US | TricValve® Transcatheter Bicaval Valve System, TricValve System | P+F Products + Features USA Inc., P+F Products + Features GmbH, Meditrial USA Inc. | Tricuspid Regurgitation, Tricuspid Valve Disease | 11/25 | 09/29 | | |
| Recruiting | N/A | 650 | Europe, Canada, Japan, US, RoW | Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT) | Medtronic Cardiovascular | Moderate Aortic Valve Stenosis | 02/26 | 12/34 | | |
| Enrolling by invitation | N/A | 200 | Europe, Canada, US | Transcatheter Tricuspid Valve Replacement | Montefiore Medical Center, The Cleveland Clinic, University of Toronto, University Hospital, Bordeaux | Tricuspid Regurgitation | 08/26 | 08/27 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
| Boudoulas, Konstantinos |
GenePHIT, NCT05598333: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure |
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| Recruiting | 2 | 150 | US | AB-1002, Gene Therapy, NAN-101 | Asklepios Biopharmaceutical, Inc. | Congestive Heart Failure | 10/26 | 12/30 | | |
| Recruiting | 1 | 12 | US | 3 x 10e13vg NAN-101 | Asklepios Biopharmaceutical, Inc. | Congestive Heart Failure, Heart Failure, Heart Disease, Ischemic, Cardiovascular Diseases, Heart Failure, Systolic, Heart Failure，Congestive, Heart Arrhythmia, Heart Failure, Diastolic, Heart; Complications | 12/26 | 12/26 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
ASPIRE PH, NCT04555161: Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System |
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| Recruiting | N/A | 30 | US | Aria CV Pulmonary Hypertension System, Aria CV PH System | Aria CV, Inc | Pulmonary Arterial Hypertension, Pulmonary Hypertension, Right Heart Dysfunction | 10/25 | 10/26 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion |
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| Active, not recruiting | N/A | 450 | Europe, Canada, US | Investigational PFO Closure Device, Standard of Care PFO Closure Device | Occlutech International AB | Stroke, Patent Foramen Ovale, PFO | 11/25 | 10/26 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Recruiting | N/A | 1000 | Canada, US | | Medstar Health Research Institute | Mitral Valve Disease | 02/27 | 02/27 | | |
| Recruiting | N/A | 3784 | Europe, US, RoW | Coronary and peripheral stents, Pacing catheters, Vascular plugs, Measurement and imaging (FFR and OCT), Peripheral dilatation catheters, Coronary dilatation catheters, Coronary and peripheral guidewires, Vessel closure/compression devices, Vascular access introducers | Abbott Medical Devices | Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism | 11/30 | 11/31 | | |
| Kojović, Maja |
NCT04692844: Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor |
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| Completed | N/A | 61 | Europe | Propranolol, Primidone | University Medical Centre Ljubljana | Essential Tremor | 12/22 | 12/22 | | |
NCT05683925: Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Characteristics in Parkinson's Disease |
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| Completed | N/A | 30 | Europe | Noninvasive transcutaneous auricular vagus nerve stimulation at 100Hz, taVNS100, Noninvasive transcutaneous auricular vagus nerve stimulation at 25Hz, taVNS25, Noninvasive transcutaneous earlobe stimulation at 25Hz, sVNS | University Medical Centre Ljubljana | Parkinson Disease, Gait Disorders, Neurologic | 02/23 | 02/23 | | |
NCT04825119: Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen |
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| Recruiting | N/A | 110 | Europe | Nusinersen, Spinraza | University Medical Centre Ljubljana | Tremor, Involuntary Movements, SMA, MND (Motor Neurone DIsease) | 07/21 | 07/21 | | |
| Coressel, Alexa |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Dion, Dellia |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Tramell, Lynette |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
| Recruiting | N/A | 2650 | Europe, Canada, Japan, US, RoW | Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 08/27 | 08/30 | | |
