| Wang, Dong-Xin |
NCT03629262: Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery |
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| Active, not recruiting | 4 | 712 | RoW | Dexmedetomidine, Sufentanil analgesia, Placebo | Peking University First Hospital, Beijing Jishuitan Hospital | Elderly, Orthopedic Surgery, Analgesia, Dexmedetomidine, Postoperative Delirium, Long-term Outcome | 12/19 | 12/22 | | |
NCT03933306: Intraoperative Goal-directed Blood Pressure and Dexmedetomidine on Outcomes |
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| Active, not recruiting | 4 | 496 | RoW | Dexmedetomidine, Dexmedetomidine hydrochloride injection, Placebo, Normal saline, Goal-directed blood pressure management, Routine blood pressure management | Peking University First Hospital | Blood Pressure, Dexmedetomidine, High-risk Patients, Abdominal Surgery, Postoperative Complications | 10/20 | 05/24 | | |
NCT04964219: Analgesic Effects of Low-dose S-ketamine in Major Spine Fusion Surgery |
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| Recruiting | 4 | 164 | RoW | S-ketamine, Placebo | Peking University First Hospital | S-ketamine, Postoperative Analgesia, Spine Fusion | 12/24 | 12/24 | | |
NCT04861337: Remimazolam and Postoperative Nausea and Vomiting in High-risk Patients |
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| Completed | 4 | 552 | RoW | Remimazolam, Remimazolam group, Placebo, Placebo group | Peking University First Hospital | Postoperative Nausea and Vomiting, Benzodiazepine, High-risk Patients | 12/22 | 04/23 | | |
NCT04955249: Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery |
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| Recruiting | 4 | 1440 | RoW | Dexmedetomidine, Intervention group, Placebo, Control group | Peking University First Hospital | Elderly, Hip Fracture Surgery, Patient-controlled Analgesia, Dexmedetomidine, Postoperative Delirium | 08/23 | 08/25 | | |
NCT05698407: Dexmedetomidine-Ropivacine Versus Sufentanil-Ropivacaine for Epidural Labor Analgesia |
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| Completed | 4 | 200 | RoW | Dexmedetomidine, Dexmedetomidine-ropivacaine combination, Sufentanil, Sufentanil-ropivacaine combination | Peking University First Hospital | Pregnancy Related | 06/23 | 08/23 | | |
NCT06231355: Liposomal vs. Conventional Bupivacaine for Pain Control |
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| Recruiting | 4 | 60 | RoW | Performing paravertebral nerve block with lipo-bupivacaine, 艾恒平 (Ai Heng Ping), Bupivacaine liposome injection, Performing paravertebral nerve block with bupivacaine, Bupivacaine injection | Peking University First Hospital | Local Anesthetics, Analgesia, Regional Block, Paravertebral Block | 06/24 | 07/24 | | |
NCT05732064: Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality |
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| Recruiting | 4 | 180 | RoW | Dexmedetomidine, Esketamine, Normal saline | Peking University First Hospital | Breast Cancer, Perioperative Period, Dexmedetomidine, Esketamine, Sleep Quality | 03/24 | 07/24 | | |
NCT06399185: Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort |
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| Recruiting | 4 | 1740 | RoW | Normal saline, Placebo, Dexmedetomidine, Esketamine, Combined dexmedetomidine-esketamine | Peking University First Hospital, Peking University Shenzhen Hospital | Urinary Catheter, Catheter-related Bladder Discomfort, Dexmedetomidine, Esketamine | 04/27 | 05/27 | | |
NCT04025840: Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery |
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| Recruiting | 4 | 260 | RoW | Epidural block, Epidural anesthesia/analgesia, Dexamethasone, Glucocorticoids | Peking University First Hospital, Peking University Cancer Hospital & Institute, The Second Affiliated Hospital of Chongqing Medical University | Pancreatic Cancer, Surgery, Epidural Block, Dexamethasone, Overall Survival | 07/24 | 07/26 | | |
NCT06411665: Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting |
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| Recruiting | 4 | 252 | RoW | Oliceridine, Oliceridine for injection, Morphine, Morphine for injection | Peking University First Hospital | Postoperative Nausea and Vomiting | 12/26 | 12/26 | | |
NCT05698394: Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth |
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| Active, not recruiting | 4 | 364 | RoW | Esketamine, Placebo, normal saline, 0.9% sodium chloride | Peking University First Hospital | Prenatal Depression, Ketamine, Postpartum Depression | 10/25 | 11/25 | | |
NCT05718544: Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes |
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| Active, not recruiting | 4 | 199 | RoW | Esketamine, Dexmedetomidine, Sufentanil | Peking University First Hospital | Scoliosis Correction, Postoperative Analgesia, Esketamine, Dexmedetomidine, Chronic Postsurgical Pain | 09/24 | 10/24 | | |
NCT06566469: Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium |
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| Not yet recruiting | 4 | 340 | RoW | Dexmedetomidine, Esketamine, Normal saline | Peking University First Hospital | Older Patients, Nasal Administration, Dexmedetomidine, Esketamine, General Anesthesia, Emergence Delirium | 08/26 | 09/26 | | |
NCT06566482: Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA |
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| Recruiting | 4 | 100 | RoW | Dexmedetomidine-esketamine combination, Dexmedetomidine-esketamine group, Placebo, Placebo group | Peking University First Hospital | Obstructive Sleep Apnea, Surgery, Dexmedetomidine, Esketamine, Postoperative Sleep Quality | 09/25 | 12/25 | | |
NCT06613243: Different Doses of Dexmedetomidine Combined With Esketamine in Women Undergoing Cesarean Delivery |
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| Completed | 4 | 120 | RoW | Esketamine 0.2 mg/kg, Esketamine 0.2 mg/kg + dexmedetomidine 0.1 µg/kg, Esketamine 0.2 mg/kg + dexmedetomidine 0.15 µg/kg, Esketamine 0.2 mg/kg + dexmedetomidine 0.2 µg/kg | Peking University First Hospital | Cesarean Delivery, Esketamine, Neuropsychiatric Symptoms, Dexmedetomidine | 12/24 | 12/24 | | |
NCT05950646: Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality |
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| Recruiting | 4 | 154 | RoW | Dexmedetomidine, Esketamine, Normal saline | Peking University First Hospital, Beijing Hospital | Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine, Esketamine, Sleep Quality | 12/24 | 12/27 | | |
NCT05718024: Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality With Mechanical Ventilation |
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| Recruiting | 4 | 174 | RoW | Dexmedetomidine-esketamine, Propofol-remifentanil | Peking University First Hospital | Intensive Care Unit, Mechanical Ventilation, Dexmedetomidine, Esketamine, Sleep Quality | 06/25 | 07/25 | | |
NCT06062550: Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery |
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| Not yet recruiting | 4 | 312 | RoW | Esketamine | Peking University First Hospital | Scoliosis Correction, Esketamine, Dexmedetomidine, Postoperative Analgesia, Chronic Postsurgical Pain | 12/25 | 12/26 | | |
NCT06087510: Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes |
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| Not yet recruiting | 4 | 312 | RoW | Esketamine | Peking University First Hospital | Scoliosis Correction, Postoperative Analgesia, Esketamine, Dexmedetomidine, Chronic Postsurgical Pain | 03/26 | 12/26 | | |
NCT05343260: Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery |
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| Active, not recruiting | N/A | 1228 | RoW | Sevoflurane, Sevoflurane for inhalation, Propofol, Propofol for injection | Peking University First Hospital | Aged, Neoplasms, Surgical Procedure, Operative, Anesthesia, Inhalation, Anesthesia, Intravenous, Survival | 09/17 | 09/22 | | |
NCT03624595: Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery |
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| Active, not recruiting | N/A | 502 | RoW | Dexmedetomidine, Low-dose dexmedetomidine infusion, Placebo, Normal saline infusion | Dong-Xin Wang, Fu Wai Hospital, Beijing, China | Cardiac Surgery, Cardiopulmonary Bypass, Dexmedetomidine, Delirium, Survival | 07/21 | 08/24 | | |
NCT03289325: Dexmedetomidine and Long-term Outcomes in Elderly Patients After Cardiac Surgery |
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| Completed | N/A | 285 | RoW | dexmedetomidine hydrochloride for injection, Aibeining (trade name), 0.9% sodium chloride for injection, Normal saline | Peking University First Hospital, Chinese Academy of Medical Sciences, Fuwai Hospital | Cardiac Surgery, Dexmedetomidine, Long-term Outcome, Mortality, Quality of Life | 05/22 | 05/22 | | |
NCT03012971: Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery |
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| Active, not recruiting | N/A | 1500 | RoW | Dexmedetomidine supplemented morphine analgesia, Morphine analgesia | Peking University First Hospital, Affiliated Hospital of Hebei University, Qingdao Municipal Hospital, The Second Affiliated Hospital of Air Force Medical University, Beijing Chao Yang Hospital, Beijing Shijitan Hospital, Capital Medical University, Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Beijing Ditan Hospital, Guizhou Provincial People's Hospital, The Third Xiangya Hospital of Central South University, Shanxi Provincial Cancer Hospital, Tianjin Hospital of ITCWM-Nankai Hospital, Zhongda Hospital | Elderly, Surgery, Analgesia, Dexmedetomidine, Long-term Outcome | 05/22 | 05/24 | | |
NCT03012984: Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium |
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| Completed | N/A | 1500 | RoW | Dexmedetomidine supplemented morphine analgesia, Morphine analgesia | Peking University First Hospital, Affiliated Hospital of Hebei University, Qingdao Municipal Hospital, The Second Affiliated Hospital of Air Force Medical University, Peking University International Hospital, Guizhou Provincial People's Hospital, The Third Xiangya Hospital of Central South University, Shanxi Provincial Cancer Hospital, Tianjin Hospital of ITCWM-Nankai Hospital, Zhongda Hospital, Chongqing University Fuling Hospital | Elderly, Surgery, Analgesia, Dexmedetomidine, Complication, Postoperative, Delirium | 05/22 | 06/22 | | |
NCT04377633: Anesthesia-handover Checklist and Perioperative Outcomes in Elderly |
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| Completed | N/A | 1421 | RoW | Oral handover, Checklist handover | Peking University First Hospital | Elderly Patients, Major Surgery, Anesthesia; Adverse Effect, Prevention, Postoperative Complications | 11/23 | 12/23 | | |
NCT03927378: Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression |
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| Completed | N/A | 364 | RoW | S-ketamine, S-ketamine hydrochloride, Placebo, Normal saline | Peking University First Hospital, Peking University International Hospital, Hunan Provincial Maternal and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, Women's Hospital School Of Medicine Zhejiang University | Prenatal Depression, Ketamine, Postpartum Depression | 08/22 | 08/22 | | |
NCT04940091: Epidural Analgesia and Maternal Fever During Labor |
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| Recruiting | N/A | 780 | RoW | Epidural analgesia, No other intervention | Peking University First Hospital, Guangdong Women and Children Hospital, Tangshan Maternal and Child Health Hospital, Dongguan Maternal and Child Health Hospital, Beijing Haidian Maternal and Child Health Hospital, Beijing Fuxing Hospital, Fourth Hospital of Shijiazhuang City, Xiamen Maternity & Child Care Hospital | Epidural Analgesia, Analgesic Effect, Fever | 09/22 | 10/22 | | |
NCT04876937: Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients |
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| Recruiting | N/A | 116 | RoW | Dexmedetomidine, Dexmedetomidine hydrochloride, Placebo (normal saline), Normal saline | Peking University First Hospital, China-Japan Friendship Hospital, Beijing Hospital, Beijing Friendship Hospital, Beijing Shijitan Hospital, Capital Medical University, Beijing Tongren Hospital | Adult, Intensive Care Unit, Sepsis, Mechanical Ventilation, Delirium, Dexmedetomidine | 03/23 | 04/24 | | |
NCT04209218: Intraoperative Blood Pressure Management and Dexamethasone in Lung Cancer Surgery |
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| Recruiting | N/A | 1988 | RoW | Dexamethasone, Glucocorticoids, Targeted blood pressure management, Placebo, Normal saline, Routine blood presure management | Peking University First Hospital | Lung Cancer, Surgery, Blood Pressure Management, Dexamethasone, Overall Survival, Postoperative Complications | 12/23 | 12/26 | | |
NCT05246007: Nocturnal Low-dose Dexmedetomidine Infusion and Perioperative Sleep Quality |
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| Not yet recruiting | N/A | 432 | RoW | Dexmedetomidine, Dexmedetomidine for infusion, Normal Saline, Normal Saline for infusion | Peking University First Hospital, Beijing Hospital | Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine, Sleep Quality | 12/23 | 12/26 | | |
NCT05537155: Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery |
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| Not yet recruiting | N/A | 112 | RoW | Buccal acupuncture in addition to routine care, Routine care | Peking University First Hospital, Beijing Jishuitan Hospital | Older Patients, Orthopedic Surgery, Postoperative Delirium, Acupuncture, Treatment | 01/24 | 03/24 | | |
NCT05494502: Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients |
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| Recruiting | N/A | 1206 | RoW | Erector spinae plane block, Control group | Peking University First Hospital, Peking University Cancer Hospital & Institute | Breast Neoplasms, Mastectomy, Nerve Block, Dexmedetomidine, Pain, Postoperative, Chronic Pain, Prognosis | 01/24 | 07/27 | | |
NCT05210764: General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia |
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| Recruiting | N/A | 366 | RoW | propofol, Propofol anesthesia group, sevoflurane, Sevoflurane anesthesia group, S-ketamine, S-ketamine anesthesia group | Peking University First Hospital | General Anesthetic, Electroencephalogram | 03/26 | 08/26 | | |
NCT05576766: Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy |
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| Not yet recruiting | N/A | 90 | RoW | Routine care, ERAS management pathway | Peking University First Hospital | Prostate Cancer, Prostatectomy, Enhanced Recovery After Surgery, Prehabilitation, Length of Hospital Stay | 05/24 | 07/24 | | |
NCT04964206: Neuraxial Labor Analgesia and Offspring Neurodevelopment |
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| Recruiting | N/A | 5580 | RoW | Neuraxial labor analgesia, No neuraxial labor analgesia | Dong-Xin Wang, Beijing Obstetrics and Gynecology Hospital, Ningxia Women and Children's Hospital, Taiyuan central hospital | Offspring, Adult, Labor Pain, Maternal Anesthesia and Analgesia Affecting Fetus or Newborn, Neurodevelopmental Delay, Postpartum Depression | 05/24 | 05/26 | | |
NCT05626153: Anesthesia Quality Improvement and Patients With Planned ICU Admission |
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| Not yet recruiting | N/A | 2000 | RoW | Routine anesthesia care, Improved anesthesia care | Peking University First Hospital | Anesthesia, Extubation, Intensive Care Unit, Postoperative Complications | 05/24 | 07/24 | | |
NCT06256354: Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival |
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| Recruiting | N/A | 3992 | RoW | Routine thermal management, Target temperature management | Peking University First Hospital, Peking University | Hypothermia, Delirium, Long-term Survivors, Cancer Surgery | 02/29 | 01/30 | | |
NCT05939193: Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC |
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| Recruiting | N/A | 168 | RoW | Urine-guided hydration, Forced administration of furosemide, Routine hydration, Routine administration of furosemide | Peking University First Hospital, Aerospace Center Hospital | Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy, Hydration, Diuresis, Acute Kidney Injury, Postoperative Complications | 07/24 | 01/25 | | |
NCT06003218: Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation |
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| Recruiting | N/A | 88 | RoW | Dexmedetomidine-esketamine combination, Remifentanil, Oxycodone | Peking University First Hospital | Liver Cancer, Radiofrequency Ablation, Esketamine, Dexmedetomidine | 07/24 | 08/24 | | |
NCT06468436: Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients |
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| Not yet recruiting | N/A | 1508 | RoW | Dexmedetomidine-Esketamine Combination, Dexmedetomidine hydrochloride, Esketamine hydrochloride, Dexmedetomidine | Peking University First Hospital, Peking University International Hospital, Tianjin Medical University General Hospital | Aged, Intensive Care Units, Ventilators, Mechanical, Dexmedetomidine, Esketamine, Delirium | 06/30 | 12/30 | | |
| Recruiting | N/A | 6254 | Europe, Japan, US, RoW | Tight pressure management, Routine pressure management | The Cleveland Clinic | Blood Pressure | 12/26 | 04/27 | | |
NCT04204798: Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery |
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| Recruiting | N/A | 1410 | RoW | Dexmedetomidine, Placebo, Normal saline | Peking University First Hospital, Peking University Third Hospital, Beijing Hospital | Elderly, Surgery, Intensive Care Unit, Dexmedetomidine, Overall Survival | 01/25 | 01/25 | | |
NCT06793163: Diagnosis and Allergen Identification of Perioperative Anaphylaxis |
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| Not yet recruiting | N/A | 115 | RoW | | Peking University First Hospital | Perioperative/Postoperative Complications, Anaphylaxis, Tryptase, Allergens, Skin Testing | 12/27 | 12/27 | | |
NCT06482749: Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery |
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| Not yet recruiting | N/A | 568 | RoW | Repetitive transcranial magnetic stimulation, Sham stimulation | Peking University First Hospital, Xijing Hospital, Air Force Medical University, Peking University Shenzhen Hospital | Older Patients, Cognitive Impairment, Repetitive Transcranial Magnetic Stimulation, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder | 08/28 | 12/29 | | |
NCT04451538: Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery |
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| Recruiting | N/A | 970 | RoW | Nutritional intervention group, Control group | Peking University First Hospital, The Forth Medical Center of PLA General Hospital, Tianjin Orthopedic Hospital | Elderly Patients, Malnutrition, Hip Fractures, Nutritional Intervention, Perioperative Outcomes, Survival | 06/25 | 07/25 | | |
NCT06030804: Perioperative Dexmedetomidine and Long-term Survival After Cancer Surgery |
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| Recruiting | N/A | 4532 | RoW | Dexmedetomidine, Dexmedetomidine hydrochloride, Placebo, Normal saline | Peking University First Hospital, Peking University | Elderly, Cancer Surgery, Dexmedetomidine, Long-Term Survivors | 09/25 | 10/28 | | |
NCT05149196: Goal-directed Hemodynamic Management and Kidney Injury After Radical Nephrectomy or Nephroureterectomy |
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| Not yet recruiting | N/A | 1724 | RoW | Targeted hemodynamic management, Routine care | Peking University First Hospital | Nephrectomy, Nephroureterectomy, Hemodynamic Management, Acute Kidney Injury, Chronic Kidney Diseases | 12/32 | 12/34 | | |
NCT03629418: Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery |
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| Recruiting | N/A | 612 | RoW | Targeted blood-pressure management, Norepinephrine, Routine blood-pressure management, Phenylephrine and other vasopressors | Peking University First Hospital | Coronary Artery Bypass, Off-Pump, Intraoperative Hypotension, Acute Kidney Injury, Preventive Medicine, Intraoperative Care | 12/25 | 07/26 | | |
NCT04715581: Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty |
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| Recruiting | N/A | 538 | RoW | Preoperative nutritional optimization, Preoperative exercise training, Postoperative exercise training | Peking University First Hospital | Old Age; Debility, Digestive Cancer, Surgery, Preoperative Rehabilitation, Nutrition Therapy, Outcomes | 12/25 | 12/27 | | |
| Yi, Fu |
SINUS, NCT06516822: CPVI With Modified Linear Ablation Versus CPVI in Patients With Long-standing Persistent Atrial Fibrillation |
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| Recruiting | N/A | 320 | RoW | CPVI-MLA, CPVI only | The First Affiliated Hospital with Nanjing Medical University | Long-standing Persistent Atrial Fibrillation, Ablation | 12/27 | 12/27 | | |
| LI, Chunyin |
| No trials found |
