THRIVE-131, NCT04935879: A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises |
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| Completed | 3 | 243 | Europe, US, RoW | Inclacumab, Placebo | Pfizer | Sickle Cell Disease, Vaso-occlusive Pain Episode in Sickle Cell Disease, Vaso-occlusive Crisis | 06/24 | 06/24 | | |
| Active, not recruiting | N/A | 45 | US | Healthy volunteers without SCT, Healthy volunteers with SCT, Volunteers with SCD | UConn Health | Sickle Cell Disease, Sickle Cell Trait | 12/25 | 12/25 | | |
| Not yet recruiting | N/A | 48 | US | Hemanext ONE System, Conventional RBCs | Hemanext, Emory University, University of Connecticut, University of Pittsburgh Medical Center, Johns Hopkins All Children's Hospital, Johns Hopkins University | Sickle Cell Anaemia, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0) | 02/28 | 06/28 | | |
PROSPECT, NCT04930445: Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD |
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| Terminated | N/A | 262 | US | Oxbryta® (voxelotor) 500mg Tablets, Voxelotor, Oxbryta® | Pfizer, Pfizer | Sickle Cell Disease | 10/24 | 10/24 | | |