| Zhang, Anna |
NCT05115942: Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Viral Hepatitis B Phase 3 Trial. |
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| Completed | 3 | 248 | RoW | Hydronidone capsules, F351, The placebo capsules, N | Beijing Continent Pharmaceutical Co, Ltd. | Liver Fibrosis | 10/24 | 10/24 | | |
NCT05905172: Hydronidone Capsules in Long-term Treatment in Patients With Chronic Viral Hepatitis B Liver Fibrosis |
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| Recruiting | 3 | 248 | RoW | Hydronidone capsules, F351, The placebo capsules, N | Beijing Continent Pharmaceutical Co, Ltd. | Liver Fibrosis | 06/28 | 10/28 | | |
| Chen, Yu |
NCT04766307: A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2 |
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| Recruiting | 4 | 1100 | RoW | Interleukin-2, IL-2 | Beijing Chest Hospital | Tuberculosis, Pulmonary | 12/21 | 12/21 | | |
| Completed | 4 | 354 | RoW | PZA sensitivity guided ultra-short all Oral Regimen, Standardized Shorter Regimen | Huashan Hospital | Multidrug Resistant Tuberculosis | 08/24 | 08/24 | | |
NCT06041425: The Effects of Oxycodone Versus Sufentanil on Pain and Inflammatory Response After TACE |
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| Completed | 4 | 40 | RoW | Oxycodone, preemptive analgesia, Sufentanil | The First Affiliated Hospital with Nanjing Medical University | Hepatocellular Carcinoma, Transcatheter Arterial Chemoembolization, Pain, Inflammation | 12/23 | 12/23 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
MRG002-006, NCT04839510: A Study of MRG002 in the Treatment of HER2-positive Unresectable Locally Advanced or Metastatic Urothelium Cancer |
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| Recruiting | 2 | 58 | RoW | MRG002 | Shanghai Miracogen Inc. | Locally Advanced Urothelial Cancer, Metastatic Urothelial Carcinoma | 06/22 | 09/22 | | |
NCT05114603: A Phase II Clinical Trial to Evaluate HLX208 in Advanced Melanoma Patients With BRAF V600 Mutation |
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| Recruiting | 2 | 30 | RoW | HLX208 | Shanghai Henlius Biotech | Advanced Melanoma | 08/23 | 08/24 | | |
NCT05823246: Safety and Efficacy Study of QLF31907 in Advanced Melanoma and Urothelial Carcinoma |
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| Recruiting | 2 | 66 | RoW | QLF31907 | Qilu Pharmaceutical Co., Ltd. | Melanoma, Urothelial Carcinoma | 10/23 | 07/24 | | |
NCT04614740: The Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors |
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| Recruiting | 2 | 115 | RoW | VC004 | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced Solid Tumor, Metastatic Solid Tumor | 01/24 | 06/24 | | |
NCT05664139: Recombinant Human Adenovirus Type 5 Injection Combined With PD-1 Monoclonal Antibody and Nab-paclitaxel in the Treatment of Patients With Liver Metastases From Malignant Melanoma |
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| Not yet recruiting | 2 | 30 | NA | Recombinant Human Adenovirus Type 5 Injection,Camrelizumab,Nab-paclitaxel | Fujian Cancer Hospital, Jiangsu Hengrui Pharmaceutical Co., Ltd., SunWay Biotech Co., LTD. | Malignant Melanoma, Liver Metastases | 12/24 | 12/25 | | |
NCT06081920: A Study of IBI363 in Subjects With Advanced Melanoma |
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| Recruiting | 2 | 120 | RoW | IBI363 | Innovent Biologics (Suzhou) Co. Ltd. | Melanoma | 06/25 | 07/26 | | |
NCT04135456: The Optimal Dose of Mannitol for Intraoperative Brain Relaxation During the Operation of Aneurysmal Subarachnoid Hemorrhage |
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| Active, not recruiting | 1/2 | 99 | RoW | Mannitol | Beijing Tiantan Hospital | Aneurysmal Subarachnoid Hemorrhage | 11/23 | 01/24 | | |
NCT05148533: A Study of Single Drug TJ011133 and Toripalimab Combine Treatment for Advanced Solid Tumor |
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| Terminated | 1/2 | 7 | RoW | TJ1133 Injection | TJ Biopharma Co., Ltd. | Advanced Solid Tumor | 02/23 | 02/23 | | |
| Recruiting | 1/2 | 380 | RoW | PM8002 | Biotheus Inc. | Malignant Neoplasm | 11/25 | 11/25 | | |
NCT06214156: A Clinical Study of T3011 in Subjects With Advanced Melanoma |
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| Recruiting | 1/2 | 42 | RoW | T3011 | Shanghai Pharmaceuticals Holding Co., Ltd | Advanced Melanoma | 09/25 | 09/25 | | |
NCT05944224: A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors. |
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| Recruiting | 1/2 | 63 | RoW | SPH4336, Cadonilimab | Shanghai Pharmaceuticals Holding Co., Ltd | Advanced Solid Tumors | 05/25 | 12/25 | | |
| Recruiting | 1 | 189 | RoW | KY-0118 | Novatim Immune Therapeutics (Zhejiang) Co., Ltd. | Neoplasms, Neoplasms by Histologic Type | 12/25 | 12/25 | | |
NCT04773951: A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors |
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| Recruiting | 1 | 156 | RoW | JS004, a recombinant humanized, IgG4κ monoclonal antibody (mAb) specific to B- and T-lymphocyte attenuator (BTLA); Toripalimab Injection | Shanghai Junshi Bioscience Co., Ltd. | Melanoma, Renal Carcinoma, Urothelial Carcinoma | 02/24 | 08/24 | | |
NCT05989958: The Safety and Tolerability Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver Failure |
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| Recruiting | 1 | 12 | NA | HepaCure | Hexaell Biotech Co., Ltd. | Acute on Chronic Hepatic Failure, Liver Failure, Hepatitis | 09/24 | 09/24 | | |
NCT04936178: A Study of NB003 in Patients With Advanced Malignancies |
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| Recruiting | 1 | 258 | Europe, US, RoW | NB003 tablets | Ningbo Newbay Technology Development Co., Ltd | Advanced Solid Tumor | 07/25 | 12/25 | | |
| Recruiting | 1 | 144 | US, RoW | ADRX-0706 | Adcentrx Therapeutics | Solid Tumors, Triple Negative Breast Cancer (TNBC), Urothelial Cancer, Cervical Cancer | 09/25 | 12/26 | | |
| Completed | N/A | 89 | RoW | Bedaquiline, BDQ, Pyrazinamide, PZA, Linezolid, LZD, Cycloserine, Cs, Clofazimine, CFZ | Huashan Hospital | Multidrug Resistant Tuberculosis | 06/24 | 06/24 | | |
NCT04968028: Multi-centre Study to Evaluate ACAF Versus Laminoplasty in Treating Cervical Ossification of the Posterior Longitudinal Ligament |
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| Recruiting | N/A | 164 | RoW | ACAF, Anterior Controllable Antedisplacement and Fusion, Laminoplasty | Shanghai Changzheng Hospital, Changhai Hospital, Shanghai 6th People's Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Tongji Hospital, Peking University Shenzhen Hospital, The Second Affiliated Hospital of Harbin Medical University, Xuanwu Hospital, Beijing, Jining Medical University, The Affiliated Hospital of Qingdao University, Shanxi Bethune Hospital, Tang-Du Hospital | Ossification of Posterior Longitudinal Ligament, Cervical Spondylosis With Myelopathy | 07/25 | 12/26 | | |
rTMS, NCT06145932: Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor |
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| Recruiting | N/A | 40 | RoW | real rTMS, sham rTMS | Second Affiliated Hospital of Soochow University | Essential Tremor | 10/26 | 12/26 | | |
| Not yet recruiting | N/A | 60 | NA | Gamma Entrainment Stimulation, Audio-assistied therapy | Beijing Tiantan Hospital, Shanghai Joyingmed Sensory Stimulation Lab | Subarachnoid Hemorrhage, Aneurysmal, Cognitive Dysfunction | 03/25 | 03/25 | | |
NCT06356506: A Study on Factors of Biochemical Response in Autoimmune Hepatitis |
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| Not yet recruiting | N/A | 630 | RoW | | Beijing Friendship Hospital | Autoimmune Hepatitis | 05/34 | 05/34 | | |
OHAVM, NCT04136860: Long-term Outcomes After Different Management Strategies for High-level Cerebral Arteriovenous Malformation |
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| Recruiting | N/A | 1000 | RoW | | Beijing Tiantan Hospital, Peking University International Hospital | Arteriovenous Malformation of Brain | 11/24 | 12/24 | | |
NCT04662918: Validation of CAGIB Score for In-hospital Mortality of Cirrhotic Patients With Acute Gastrointestinal Bleeding |
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| Recruiting | N/A | 3000 | Europe, US, RoW | | Xingshun Qi | GastroIntestinal Bleeding | 12/24 | 12/24 | | |
NCT05885828: The PRECISION-T2D Study: Precision Nutrition Study for Type 2 Diabetes |
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| Recruiting | N/A | 200 | RoW | White bread, Breakfast A, Whole wheat bread, Breakfast B, Plant-based diet, Conventional diabetic diet, Follow-up visit every 1-2 years | Westlake University, Hangzhou Third People's Hospital | Type 2 Diabetes | 12/24 | 12/33 | | |
NCT05720299: A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila on Insulin Resistance Among Obese Subjects. |
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| Recruiting | N/A | 120 | RoW | Treatment with Akkermansia muciniphila, Treatment with placebo | Yu Chen | Obesity Associated Disorder | 12/24 | 12/24 | | |
| Recruiting | N/A | 3000 | RoW | | Beijing Friendship Hospital | Drug-induced Liver Injury | 12/26 | 12/28 | | |
NCT05409482: A Real-world Study of Camrelizumab Combined With Apatinib Mesylate in Unresectable Hepatocellular Carcinoma |
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| Recruiting | N/A | 300 | RoW | | Meng Chao Hepatobiliary Hospital of Fujian Medical University, Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Hepatocellular Carcinoma | 03/26 | 03/26 | | |
| Recruiting | N/A | 100000 | RoW | Multi-disciplinary assessment | Beijing Tiantan Hospital | Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure, Aortic Diseases, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Cerebral Infarction, Occlusion and Stenosis of Precerebral Arteries, Occlusion and Stenosis of Cerebellar Arteries, Cerebral Aneurysm, Moyamoya Disease, Arteriovenous Malformation of Cerebral Vessels | 12/32 | 12/32 | | |
| Not yet recruiting | N/A | 500 | RoW | | Huashan Hospital | Multidrug Resistant Tuberculosis | 12/22 | 12/22 | | |
| Recruiting | N/A | 5000 | RoW | Surgical clipping and endovascular coiling | Beijing Tiantan Hospital, Peking University International Hospital | Aneurysmal Subarachnoid Hemorrhage | 03/32 | 04/32 | | |
| Li, Guangming |
NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( ) |
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| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | IVA337, Lanifibranor, Placebo | Inventiva Pharma | NASH - Nonalcoholic Steatohepatitis | 09/25 | 09/26 | | |
NCT05734807: A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia |
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| Completed | 2 | 74 | RoW | Nucleoside/nucleotide reverse transcriptase inhibitors (NrtIs), HH-003 and NrtIs, HH-003, NrtIs and PEG-IFN-α | Huahui Health | Chronic HBV Infection | 04/24 | 04/24 | | |
NCT06569524: Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjects With Non-alcoholic Steatohepatitis (NASH) |
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| Recruiting | 2 | 120 | RoW | TQA2225/AP025 or TQA2225/AP025 Placebo 25mg, TQA2225/AP025 or TQA2225/AP025 Placebo 50mg | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Non-alcoholic Steatohepatitis | 12/26 | 12/27 | | |
NCT06123858: Non-alcoholic Steatohepatitis Registry Platform Study |
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| Recruiting | N/A | 2500 | RoW | | AstraZeneca | NASH With Fibrosis | 12/26 | 12/26 | | |
| Li, Shuang |
NCT04694365: Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function |
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| Completed | 1 | 24 | RoW | Fluzoparib | Jiangsu HengRui Medicine Co., Ltd. | Hepatic Impairment, Healthy Subjects | 06/24 | 06/24 | | |
NCT05933824: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects |
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| Completed | 1 | 36 | RoW | LP-98 injection, placebo-controlled | Shanxi Kangbao Biological Product Co., Ltd., Institute of Pathogen Biology, Chinese Academy of Medical Sciences | Hiv | 04/24 | 04/24 | | |
NCT06005714: Effect of Pharmacokinetics in Healthy Chinese Subjects |
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| Active, not recruiting | 1 | 36 | RoW | Mindeudesivir hydrobromide tablets and Clarithromycin tablets, Mindeudesivir hydrobromide tablets and Cyclosporine softgels | Shanghai Vinnerna Biosciences Co., Ltd. | The Effects of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects | 11/23 | 12/23 | | |
NCT06732973: A Bioequivalence Study of JS005 Pre-filled Syringe and JS005 Auto-injector |
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| Not yet recruiting | 1 | 272 | RoW | JS005 | Shanghai Junshi Bioscience Co., Ltd., Sponsor GmbH | Health Volunteer | 06/25 | 12/25 | | |
NCT06771479: A Study Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine |
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| Not yet recruiting | 1 | 120 | NA | MVA strain monkeypox attenuated live vaccine (low dose), MVA strain monkeypox attenuated live vaccine (high dose), Placebo | Shanghai Institute Of Biological Products | Monkeypox | 06/25 | 05/26 | | |
NCT05170620: Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions |
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| Recruiting | N/A | 200 | RoW | laser ablation | Tongji Hospital | Squamous Intraepithelial Lesions, Laser Burn | 12/23 | 12/24 | | |
NCT05892354: Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy |
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| Recruiting | N/A | 190 | RoW | Enteral immunonutrition, Standard enteral nutrition | First Affiliated Hospital of Guangxi Medical University, Guangdong Provincial People's Hospital, Zhejiang Cancer Hospital, Zhejiang Provincial People's Hospital, Fujian Cancer Hospital, Fujian Provincial Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, The First Affiliated Hospital of Nanchang University, Second Affiliated Hospital of Nanchang University, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Qingdao Central Hospital, Huizhou Municipal Central Hospital, Haikou People's Hospital, The Second Affiliated Hospital of Hainan Medical University, Zhejiang Provincial Tongde Hospital, Guilin Medical University, China, Liuzhou Workers Hospital, Wuzhou Red Cross Hospital, Red Cross Hospital of Yulin City, First People's Hospital of Yulin, Hainan Cancer Hospital | Locally Advanced Nasopharyngeal Carcinoma | 04/25 | 04/27 | | |
NCT05510830: Diagnostic Cervical Conization for Persistent Infection or Integration of HPV |
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| Not yet recruiting | N/A | 250 | RoW | diagnostic cervical conization | Tongji Hospital, National Natural Science Foundation of China | Human Papilloma Virus Infection, Human Papilloma Virus Integration, Cervical Intraepithelial Neoplasia, Cervical Cancer, Cervical Conization | 01/28 | 01/30 | | |
NCT05300243: The Predictive Role of HPV Integration in HSIL and Cervical Cancer |
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| Recruiting | N/A | 1 | RoW | HPV integration test | Tongji Hospital | HPV Integration | 04/22 | 06/22 | | |
