| Ge, Jian |
NCT06363994: A Global Phase 3 Study of Orelabrutinib+BR Vs.BR in Pts with TN MCL |
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| Recruiting | 3 | 476 | RoW | Orelabrutinib, Bendamustine Injection, Rituximab, Orelabrutinib Placebo | InnoCare Pharma Inc. | Mantle Cell Lymphoma | 06/31 | 06/32 | | |
ICP-CL-01203, NCT06378138: ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma |
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| Recruiting | 2/3 | 226 | RoW | ICP-248, Orelabrutinib | Beijing InnoCare Pharma Tech Co., Ltd. | Hematologic Malignancies | 11/30 | 07/31 | | |
NCT05698147: Selinexor in Combination With MTX+Ritu to Treat R/R CNSL |
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| Recruiting | 1/2 | 30 | RoW | Selinexor, ATG-010, Rituximab, RiTUXimab Injection, Methotrexate, MTX | Tong Chen, MD, Antengene Corporation | Central Nervous System Lymphoma | 06/26 | 12/26 | | |
NCT06532643: Safety and Efficacy of Anti-CD20/CD30 CAR-T Cells in Subjects with Relapsed/Refractory Lymphoma |
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| Recruiting | 1 | 9 | RoW | anti-CD20/CD30-CAR-T cells, Fludarabine, Cyclophosphamide | Shanghai First Song Biotechnology Co., LTD | Relapsed/Refractory Lymphoma | 09/25 | 09/26 | | |
NCT06532630: Anti-CD19-CAR-T Cells in Subjects With Relapsed/Refractory B Cell Malignancies |
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| Recruiting | 1 | 9 | RoW | Anti-CD19-CAR-T cells, Fludarabine, Cyclophosphamide | Shanghai First Song Biotechnology Co., LTD | B-Cell Malignancy | 09/25 | 09/26 | | |
| Recruiting | 1 | 105 | RoW | ICP-248 | Beijing InnoCare Pharma Tech Co., Ltd. | Hematological Malignancies | 08/24 | 10/26 | | |
NCT06647160: Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control |
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| Not yet recruiting | N/A | 200 | RoW | Blue star MAX-5 spectacle lens, Single-vision spectacle lens | Zhongshan Ophthalmic Center, Sun Yat-sen University | Myopia, Progressive | 12/26 | 03/27 | | |
| Lin, Haotian |
NCT04003558: Deep Learning Algorithms for Prediction of Lymph Node Metastasis and Prognosis in Breast Cancer MRI Radiomics (RBC-01) |
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| Recruiting | N/A | 1500 | RoW | No interventions | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sun Yat-sen University, Tungwah Hospital of Sun Yat-Sen University, Shunde Hospital of Southern Medical University, Zhongshan Ophthalmic Center, Sun Yat-sen University | Breast Neoplasm Female, Early-stage Breast Cancer, Radiomics, Axillary Lymph Node, Survival, Prosthesis | 05/20 | 01/25 | | |
RBC-02, NCT04004559: MRI Radiomics Assessing Neoadjuvant Chemotherapy in Breast Cancer to Predict Lymph Node Metastasis and Prognosis |
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| Recruiting | N/A | 600 | RoW | No interventions | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sun Yat-sen University, Tungwah Hospital of Sun Yat-Sen University | Invasive Breast Cancer, Neoadjuvant Chemotherapy, Radiomics, Axillary Lymph Node, Prognosis | 10/20 | 05/25 | | |
NCT06756009: Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters |
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| Recruiting | N/A | 500 | RoW | Ophthalmic examination, General Condition Examination | Zhongshan Ophthalmic Center, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Second Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial People's Hospital, Nanfang Hospital of Southern Medical University, Guangdong of China, Zhongshan People's Hospital, Guangdong, China, Guangdong Provincial People's Hospital, China, First People's Hospital of Foshan | Diagnostic Techniques, Ophthalmological, Liver Transplantation, Liver Cirrhoses | 12/25 | 12/26 | | |
NCT03230799: Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery |
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| Recruiting | N/A | 100 | RoW | minimal invasive lens surgery, traditional cataract surgery | Sun Yat-sen University | Congenital Cataract | 06/22 | 12/22 | | |
NCT05490823: Validation of a Smartphone App for Anemia Screening Among General Population |
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| Recruiting | N/A | 1000 | RoW | A smartphone app for anemia screening | Sun Yat-sen University | Anemia | 12/22 | 12/22 | | |
| Recruiting | N/A | 6000 | RoW | | Sun Yat-sen University | Ophthalmology, Lens Opacities, Biological Age | 12/22 | 12/22 | | |
| Recruiting | N/A | 200 | RoW | | Sun Yat-sen University | Healthy, Vision; Disorder, Loss | 12/22 | 04/23 | | |
NCT05615519: Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus |
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| Recruiting | N/A | 300 | RoW | A new technology based on 3D reconstruction and deep learning algorithm to achieve an automatic diagnosis of strabismus based on patient-sourced videos of programmatic cover tests. | Sun Yat-sen University | Strabismus, Exotropia, Esotropia, Vertical Strabismus | 03/23 | 04/23 | | |
NCT06015178: Enhancing Medical Researchers' Self-learning With an Intelligent Language Model |
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| Recruiting | N/A | 60 | RoW | Intelligent Language Model, control | Zhongshan Ophthalmic Center, Sun Yat-sen University | Medical Artificial Intelligence, Interdisciplinary Research, Self-Directed Learning | 10/23 | 04/24 | | |
NCT03908359: Comparison of the Effect of Minimal Invasive Lens Surgery and Traditional Cataract Surgery |
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| Recruiting | N/A | 100 | RoW | traditional cataract surgery, minimal invasive lens surgery | Sun Yat-sen University | Congenital Cataract | 11/23 | 12/23 | | |
NCT06229379: The Effects of a Large Language Model on Clinical Questioning Skills |
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| Completed | N/A | 84 | RoW | "Digital twin patient", Interaction with real patients | Sun Yat-sen University | Cataract, Glaucoma, Diabetic Retinopathy, Keratitis, Conjunctivitis | 05/24 | 08/24 | | |
NCT05645341: Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular Surface |
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| Completed | N/A | 535 | RoW | screening system for ocular surface malignant tumors | Sun Yat-sen University | Orbital Neoplasms, Conjunctival Neoplasms, Eye Neoplasms | 06/23 | 06/23 | | |
NCT05865860: Application and Safety Evaluation of 3D Visualization System in Microsurgical Training |
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| Recruiting | N/A | 42 | RoW | | Zhongshan Ophthalmic Center, Sun Yat-sen University | Microsurgery, Binocular Visual Function, Nervous System | 04/24 | 04/24 | | |
NCT06633393: Effect of a Myopia Prediction System on Myopia Prevention and Control |
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| Not yet recruiting | N/A | 20000 | RoW | Feedback on Predicted High Myopia Risk at Age 18 Using the Myopia Prediction System, Feedback on Ophthalmic Examinations | Zhongshan Ophthalmic Center, Sun Yat-sen University | Myopia, Randomized Controlled Trials, Artificial Intelligence (AI) | 12/25 | 02/26 | | |
NCT04849819: the SDMEAI Study: a Multi-center Epidemiological Study |
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| Not yet recruiting | N/A | 1000 | NA | Corticosteroids, immunosuppressors, biological agents | Sun Yat-sen University | Eye Involvement of Systemic Diseaes, Adverse Drug Effect on Eye, Artificial Intelligence | 04/25 | 04/26 | | |
| Recruiting | N/A | 2500 | RoW | | Zhongshan Ophthalmic Center, Sun Yat-sen University | Eye Diseases | 02/28 | 02/29 | | |
NCT04890847: A Platform for Multidisciplinary Medical Artificial Intelligence Development |
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| Recruiting | N/A | 200 | RoW | | Sun Yat-sen University | Medical Artificial Intelligence, Medical Imaging | 04/21 | 05/21 | | |
| Recruiting | N/A | 560000 | RoW | | Sun Yat-sen University | Ophthalmology, Hospitalization | 04/21 | 12/21 | | |
NCT05058599: Reconstruction Technology to Auxiliary Diagnosis and Guarantee Patient Privacy |
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| Recruiting | N/A | 400 | RoW | DM | Sun Yat-sen University | 3D-reconstruction, Patient Privacy, Deep Learning, Digital Medicine | 09/21 | 01/22 | | |
NCT04859634: Real-time Artificial Intelligence System for Detecting Multiple Ocular Fundus Lesions by Ultra-widefield Fundus Imaging |
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| Recruiting | N/A | 2000 | RoW | Taking an ultra-widefield fundus image | Sun Yat-sen University, Shenzhen Eye Hospital, Xudong Ophthalmic Hospital, IKang Physical Examination Center, Beijing Tongren Hospital, Guangdong Provincial People's Hospital, Yangxi General Hospital People's Hospital | Artificial Intelligence, Diagnostic Imaging, Abnormality of the Fundus, Diagnostic Screening Programs | 02/22 | 12/22 | | |
NCT05527925: Effects of Visual Reconstruction on Brain Function and Structure in Children With Congenital Cataract |
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| Recruiting | N/A | 100 | RoW | MRI | Sun Yat-sen University | Congenital Cataracts | 12/22 | 06/23 | | |
NCT05223712: Artificial Intelligence System for the Detection and Prediction of Kidney Diseases Using Ocular Information |
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| Recruiting | N/A | 4000 | RoW | Diagnostic Test: Chronic Kidney Diseases | Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University | Artificial Intelligence, Ophthalmology, Kidney Diseases | 12/22 | 12/22 | | |
| Recruiting | N/A | 1000 | RoW | | Sun Yat-sen University | Cataract, Retina Disorder | 12/24 | 06/25 | | |
NCT05680090: Artificial Intelligent System for Eye Emergency Triage and Primary Diagnosis |
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| Recruiting | N/A | 100 | RoW | Artificial intelligent system for eye emergency triage and primary diagnosis | Sun Yat-sen University | Emergencies, Eye Diseases | 01/23 | 01/23 | | |
| Liu, Yizhi |
NCT03230799: Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery |
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| Recruiting | N/A | 100 | RoW | minimal invasive lens surgery, traditional cataract surgery | Sun Yat-sen University | Congenital Cataract | 06/22 | 12/22 | | |
NCT03605160: An Innovative Method Fluid-jet to to Remove Residual Lens Fibers |
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| Active, not recruiting | N/A | 740 | RoW | traditional polish, fluid-jet | Sun Yat-sen University | Posterior Capsule Opacification | 01/23 | 01/23 | | |
NCT05136950: Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation |
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| Recruiting | N/A | 228 | RoW | Secondary in-the-bag IOL fixation, Secondary ciliary sulcus IOL fixation | Zhongshan Ophthalmic Center, Sun Yat-sen University | Lens Implantation, Intraocular | 07/23 | 07/33 | | |
NCT03908359: Comparison of the Effect of Minimal Invasive Lens Surgery and Traditional Cataract Surgery |
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| Recruiting | N/A | 100 | RoW | traditional cataract surgery, minimal invasive lens surgery | Sun Yat-sen University | Congenital Cataract | 11/23 | 12/23 | | |
NCT05628129: Effect of Mobile Communication on Congenital Ectopia Lentis Follow-up Adherence |
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| Recruiting | N/A | 114 | RoW | smartphone application service and phone reminder | Zhongshan Ophthalmic Center, Sun Yat-sen University | Ectopia Lentis | 10/24 | 11/24 | | |
NCT03589937: Ocular Development and Refractive Error Changes Among Children and Adolescent - A Longitudinal Study |
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| Active, not recruiting | N/A | 7050 | RoW | | Zhongshan Ophthalmic Center, Sun Yat-sen University | Myopia | 07/24 | 07/24 | | |
DME HOME, NCT06610747: Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT |
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| Not yet recruiting | N/A | 308 | RoW | Home-based Care Monitoring, Aflibercept 2Mg/0.05Ml Inj,Oph, Aflibercept 2-mg/0.05mL intravitreal ophthalmic injection, Laser Treatment, Standard Hospital/clinic-based Care Monitoring | Zhongshan Ophthalmic Center, Sun Yat-sen University, Dongguan Guangming Ophthalmic Hospital, The Second People's Hospital of Foshan | Diabetic Macular Edema | 04/27 | 04/27 | | |
NCT05728762: Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention |
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| Active, not recruiting | N/A | 1920 | RoW | Novel LEDs | Zhongshan Ophthalmic Center, Sun Yat-sen University | Myopia, Refractive Errors, Eye Diseases | 12/25 | 12/25 | | |
NCT05654025: Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens |
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| Recruiting | N/A | 604 | RoW | | Zhongshan Ophthalmic Center, Sun Yat-sen University | Ectopia Lentis, Dislocation, Lens | 12/27 | 12/27 | | |
| Recruiting | N/A | 5000 | RoW | | Zhongshan Ophthalmic Center, Sun Yat-sen University | Pediatric Cataract | 01/32 | 02/32 | | |
NCT05223712: Artificial Intelligence System for the Detection and Prediction of Kidney Diseases Using Ocular Information |
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| Recruiting | N/A | 4000 | RoW | Diagnostic Test: Chronic Kidney Diseases | Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University | Artificial Intelligence, Ophthalmology, Kidney Diseases | 12/22 | 12/22 | | |
NCT05565547: Multimodal Equipment for Teleophthalmology Assessment (META) |
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| Not yet recruiting | N/A | 400 | NA | META, Commercial devices | Zhongshan Ophthalmic Center, Sun Yat-sen University | Eye Diseases | 03/23 | 05/23 | | |
| Not yet recruiting | N/A | 3000 | RoW | Portable slit-lamp photography | Sun Yat-sen University | Catarct Screening, Artificial Intelligence | 06/23 | 06/23 | | |
| Chen, Weirong |
| Completed | N/A | 115 | RoW | Ophthalmic examination, Whole-exome sequencing | Zhongshan Ophthalmic Center, Sun Yat-sen University | Congenital Cataract | 12/22 | 12/22 | | |
NCT05136209: Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy |
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| Recruiting | N/A | 50 | RoW | PCCC procedure without A-vit, PCCC+A-Vit procedure | Sun Yat-sen University | Congenital Cataract | 11/26 | 11/26 | | |
| Zheng, Yingfeng |
| Recruiting | N/A | 4000 | RoW | Ophthalmic examinations, Wearable devices | Sun Yat-sen University | Myopia | 02/23 | 02/23 | | |
NCT05087173: Effectiveness of Using Interactive Consulting System to Enhance Decision Aids of COVID-19 Vaccination |
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| Recruiting | N/A | 1200 | RoW | Chatbot | Sun Yat-sen University | COVID-19 | 08/23 | 12/23 | | |
NCT05622565: Explainable Ocular Fundus Diseases Report Generation System |
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| Recruiting | N/A | 15000 | RoW | Various modalities of ocular fundus imaging | Sun Yat-sen University | Ophthalmological Disorder, Image, Body | 12/23 | 07/24 | | |
NCT05231174: Efficacy of Using Large Language Model to Assist in Diabetic Retinopathy Detection |
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| Completed | N/A | 535 | RoW | A self-evlaution tool based on Large Language Model | Sun Yat-sen University | Diagnosis, Diabetic Retinopathy | 07/23 | 07/23 | | |
NCT04246346: Effectiveness of Using Interactive Consulting System to Enhance Informed Choice |
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| Recruiting | N/A | 660 | RoW | An interactive chatbot for patient decision aid, Senior ophthalmologists | Sun Yat-sen University | Age-related Cataract | 12/23 | 12/23 | | |
| Recruiting | N/A | 120 | RoW | Home OCT monitoring model, Hospital-based monitoring with a staff-administrated OCT | Zhongshan Ophthalmic Center, Sun Yat-sen University | Macular Edema Due to Diabetes Mellitus | 12/23 | 06/24 | | |
NCT05689073: A Conversational AI System to Enhance Knowledge About Vaccines and Promote Vaccination |
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| Completed | N/A | 430 | RoW | Conversational AI system, Printed educational Brochure | Sun Yat-sen University | Vaccination Hesitancy | 08/23 | 08/23 | | |
NCT04262596: Effectiveness of an Interactive Consulting System to Enhance Patients' Decision-making: A Randomized Controlled Trial |
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| Completed | N/A | 492 | RoW | Interactive Consulting System, A traditional patient decision aid brochure | Sun Yat-sen University | Age-related Cataract | 08/23 | 08/23 | | |
DME HOME, NCT06610747: Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT |
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| Not yet recruiting | N/A | 308 | RoW | Home-based Care Monitoring, Aflibercept 2Mg/0.05Ml Inj,Oph, Aflibercept 2-mg/0.05mL intravitreal ophthalmic injection, Laser Treatment, Standard Hospital/clinic-based Care Monitoring | Zhongshan Ophthalmic Center, Sun Yat-sen University, Dongguan Guangming Ophthalmic Hospital, The Second People's Hospital of Foshan | Diabetic Macular Edema | 04/27 | 04/27 | | |
| Lin, Mingkai |
NCT05130554: XEN45 in the Treatment of Chinese Patients With Primary Open-angle Glaucoma |
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| Active, not recruiting | N/A | 20 | RoW | XEN45 gel stent implantation, XEN | Zhongshan Ophthalmic Center, Sun Yat-sen University, Allergan | Glaucoma, Glaucoma, Open-Angle, Surgery | 06/22 | 09/22 | | |
NCT04495491: Predicting the Effect of Laser Peripheral Iridotomy |
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| Recruiting | N/A | 200 | RoW | pupillary block group, plateau iris group, mixing mechanism group | Zhongshan Ophthalmic Center, Sun Yat-sen University | Glaucoma | 12/20 | 03/21 | | |
| Zuo, Chengguo |
NCT06243497: Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment |
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| Recruiting | N/A | 200 | RoW | Ultrasound CycloPlasty | Zhongshan Ophthalmic Center, Sun Yat-sen University | Glaucoma, Ultrasound Cyclo Plasty, Aqueous Humor, Tear, Cytokines | 02/27 | 02/27 | | |
NCT05251792: Macular Pigment Optical Density in Primary Angle-closure Disease |
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| Recruiting | N/A | 60 | RoW | Ocular examination | Zhongshan Ophthalmic Center, Sun Yat-sen University | Glaucoma, Glaucoma, Angle-Closure, Macular Pigment Optical Density | 03/24 | 12/24 | | |
| Zheng, Weixin |
NCT06527326: the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy |
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| Recruiting | N/A | 400 | RoW | Live Combined Bifidobacterium, Placebo | Second Affiliated Hospital, School of Medicine, Zhejiang University | Central Serous Chorioretinopathy | 07/25 | 07/26 | | |
| Wang, Qiwei |
| Recruiting | N/A | 190 | RoW | | Peking University Cancer Hospital & Institute | DMMR Cancer, MSI-H, Solid Tumor | 02/26 | 02/26 | | |
| Huang, Zhihong O |
NCT05251792: Macular Pigment Optical Density in Primary Angle-closure Disease |
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| Recruiting | N/A | 60 | RoW | Ocular examination | Zhongshan Ophthalmic Center, Sun Yat-sen University | Glaucoma, Glaucoma, Angle-Closure, Macular Pigment Optical Density | 03/24 | 12/24 | | |
| Shi, Huanyang |
NCT06243497: Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment |
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| Recruiting | N/A | 200 | RoW | Ultrasound CycloPlasty | Zhongshan Ophthalmic Center, Sun Yat-sen University | Glaucoma, Ultrasound Cyclo Plasty, Aqueous Humor, Tear, Cytokines | 02/27 | 02/27 | | |
