| Chen, Xin |
OPTIMA-6, NCT05410925: Efficacy and Safety of a Half-dose Bolus of r-SAK Prior to Primary PCI in ST-elevation Myocardial Infarction |
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| Recruiting | 4 | 2260 | RoW | Recombinant staphylokinase, Placebo | The First Affiliated Hospital with Nanjing Medical University | ST Elevation Myocardial Infarction | 12/26 | 12/27 | | |
NCT05182463: Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients |
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| Recruiting | 4 | 5000 | RoW | Peginterferon Alfa-2B, Nucleoside Analogs | Third Affiliated Hospital, Sun Yat-Sen University | Hepatitis B, Chronic | 12/26 | 11/29 | | |
| Recruiting | 4 | 210 | RoW | Realgar Indigo naturalis formula, RIF, Conventional chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Zhujiang Hospital, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou First People's Hospital, Huizhou Municipal Central Hospital, First Affiliated Hospital of Shantou University Medical College, Zhongshan People's Hospital, Guangdong, China, Zhongshan Bo Ai Hospital, First Affiliated Hospital of Guangxi Medical University, LiuZhou People's Hospital, Second Xiangya Hospital of Central South University, Hainan People's Hospital | Arsenic Trioxide, Childhood ALL | 09/27 | 09/30 | | |
TQB2450-III-09, NCT04964479: A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus K Drug in the Treatment of First-line Non-small Cell Lung Cancer(NSCLC) |
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| Recruiting | 3 | 375 | RoW | TQB2450 injection, Anlotinib Hydrochloride Capsules, Pembrolizumab injection, Placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 12/22 | 03/23 | | |
NCT05003245: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD |
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| Recruiting | 3 | 388 | RoW | HLX04-O，recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection, Lucentis | Shanghai Henlius Biotech | Age Related Macular Degeneration | 08/23 | 03/24 | | |
NCT06301854: Long-term Safety of TPN171H Tablet in Erectile Dysfunction. |
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| Recruiting | 3 | 472 | RoW | TPN171H, Simmerafil | Vigonvita Life Sciences | Erectile Dysfunction | 04/25 | 04/25 | | |
NCT04937387: Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled Asthma |
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| Completed | 3 | 359 | RoW | FF/VI, FF/UMEC/VI, ELLIPTA | GlaxoSmithKline | Asthma | 08/24 | 08/24 | | |
| Recruiting | 2 | 30 | RoW | Mitoxantrone hydrochloride liposome, Venetoclax, Cytarabine,Cytosine arabinoside, Cyclophosphamide | Institute of Hematology & Blood Diseases Hospital, China | Relapse Acute Myeloid Leukemia | 05/27 | 10/27 | | |
| Recruiting | 1/2 | 60 | RoW | PM8002, nab-paclitaxel | Biotheus Inc. | TNBC | 10/26 | 10/26 | | |
NCT05001412: Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLC |
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| Recruiting | 1 | 36 | RoW | Camrelizumab; apatinib; carboplatin; etoposide | Zhou Chengzhi, Jiangsu Hengrui Pharmaceutical Co., Ltd. | Extensive Stage Small Cell Lung Cancer | 01/23 | 01/24 | | |
NCT04613115: Relationship Between Arterial Variations and Patency of Arteriovenous Fistulae |
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| Completed | N/A | 1000 | RoW | | Beijing Tongren Hospital | Arteriovenous Fistula, Ultrasound, Artery | 06/21 | 06/22 | | |
GIANT, NCT04765592: Guo's Aortic Arch Reconstruction :The Prospective ,Multiple Center Study About the Safety and Efficacy of WeFlow-Arch Modeler Embedded Branch Stent Graft System ( Study) |
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| Active, not recruiting | N/A | 88 | RoW | WeFlow-Arch Modeler Embedded Branch Stent Graft System | Hangzhou Endonom Medtech Co., Ltd. | Aortic Arch Aneurysm | 02/25 | 02/29 | | |
PLACARD, NCT06336239: PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study |
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| Recruiting | N/A | 3000 | RoW | | Beijing Anzhen Hospital | Cardiovascular Disease, Type 2 Diabetes Mellitus | 07/24 | 12/24 | | |
GRAFT, NCT05754541: Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study( Study) |
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| Recruiting | N/A | 20 | RoW | WeFlow-Tribranch Aortic Arch Stent Graft System | Hangzhou Endonom Medtech Co., Ltd. | Aortic Aneurysm and Dissection | 12/23 | 12/25 | | |
NCT05021601: Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atrial Fibrillation |
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| Recruiting | N/A | 320 | RoW | Bi-atrial ablation, Left atrial ablation | China National Center for Cardiovascular Diseases | Persistent Atrial Fibrillation | 06/25 | 07/25 | | |
NCT06385379: Guo's Aortic Arch Reconstruction: A Multicenter, Prospective Study of the Novel WeFlow-Tribranch System (GENIUS Study) |
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| Recruiting | N/A | 90 | RoW | WeFlow-Tribranch embedded aortic Triple-branch arch Stent Graft system | Hangzhou Endonom Medtech Co., Ltd. | Aortic Arch Aneurysm | 12/25 | 12/30 | | |
| Recruiting | N/A | 480 | RoW | Usual care, POST-strategy | Istituto Auxologico Italiano | Hypertension,Essential, Hypertension, Uncontrolled | 12/24 | 12/24 | | |
| Not yet recruiting | N/A | 2000 | RoW | | China-Japan Friendship Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, First Hospital of China Medical University, Henan Provincial People's Hospital, Second Xiangya Hospital of Central South University, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Sichuan University, Ruijin Hospital Affiliated to Shanghai Jiao Tong University, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China | Chronic Obstructive Pulmonary Disease (COPD), Asthma, Bronchiectasis | 07/28 | 07/28 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Active, not recruiting | N/A | 255 | RoW | EDWARDS INSPIRIS RESILIA Aortic Valve | Edwards Lifesciences, Edwards (Shanghai) Lifesciences Medical Supplies Co., Ltd., Rundo International Pharmaceutical Research & Development Co.,Ltd., Fuwai Hospital, CAMS & PUMC | Aortic Valve Replacement | 12/28 | 12/29 | | |
NCT05376618: Pilot Study on Proteomics of Erythrocyte Proteins in Patients With COPD Based on TMT Technology |
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| Completed | N/A | 30 | RoW | no intervention | Zhujiang Hospital | Protein; Disease | 07/22 | 07/22 | | |
| zhang, yang |
ETER701, NCT04234607: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer |
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| Not yet recruiting | 3 | 738 | RoW | TQB2450, Anlotinib, Etoposide, Carboplatin, TQB2450（blank）, Anlotinib（blank) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Extensive Small Cell Lung Cancer | 12/22 | 12/22 | | |
EFFECT-neo, NCT06102395: Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC |
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| Recruiting | 3 | 272 | RoW | Pembrolizumab, Cisplatin, Carboplatin, Nedaplatin, Nab paclitaxel, Docetaxel, Liposomal paclitaxel, Fluorouracil | Beijing Tongren Hospital | Head and Neck Squamous Cell Carcinoma, Neoadjuvant Therapy, Pembrolizumab | 04/27 | 04/30 | | |
NCT04412564: A Study of TQ-B3101 Capsules in Subjects With Advanced Malignant Tumor |
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| Recruiting | 2 | 200 | RoW | TQ-B3101 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Malignant Tumor | 03/21 | 09/21 | | |
NCT03941574: A Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard Therapy |
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| Recruiting | 2 | 108 | RoW | HLX10 | Shanghai Henlius Biotech | MSI-H Solid Malignant Tumor | 05/24 | 06/26 | | |
NCT04968366: Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery |
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| Active, not recruiting | 1 | 11 | RoW | Autologous dendritic cells pulsed with multiple neoantigen peptides., Temozolomide adjuvant chemotherapy, the standard-of-care adjuvant chemotherapy for GBM patients | Beijing Tiantan Hospital, ZhongSheng BioTech Inc. | Glioblastoma Multiforme of Brain | 03/24 | 12/24 | | |
| Recruiting | 1 | 12 | RoW | personalized dendritic cell injection ZSNeo-DC1.1, DC vaccine | Beijing Tiantan Hospital, ZhongSheng BioTech Inc. | WHO Grade III Gliomas, WHO Grade IV Gliomas | 12/24 | 02/25 | | |
| Recruiting | 1 | 30 | RoW | IL13Rα2 CAR-T | Yang Zhang, TCRCure Biopharma Ltd. | Glioma | 05/26 | 05/27 | | |
| Terminated | 1 | 16 | RoW | Histone H3.3-K27M Neoantigen Vaccine Therapy | Yang Zhang, TCRCure Biopharma Ltd. | Diffuse Intrinsic Pontine Glioma | 10/24 | 10/24 | | |
NCT05473923: PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas |
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| Active, not recruiting | 1 | 30 | RoW | Receiving chemotherapeutic or targeted drugs recommended by molecular tumor board. | Beijing Tiantan Hospital, Beijing GeneX Health Technology Co., Ltd | Recurrent High Grade Glioma | 12/24 | 12/24 | | |
NCT06485245: Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060304 in Healthy and Elevated LDL-C Subjects |
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| Not yet recruiting | 1 | 80 | RoW | CS060304, Pleacbo | Cascade Pharmaceuticals, Inc | MASH | 04/25 | 09/25 | | |
NCT06482905: Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma. |
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| Recruiting | 1 | 52 | US, RoW | Anti-B7-H3 Chimeric Antigen Receptor T-Cell (CAR-T Cell) Injection/TX103 | Tcelltech Inc., Beijing Tiantan Hospital, Mayo Clinic | High-grade Glioma, WHO Grade Ⅳ Glioma | 09/26 | 06/27 | | |
NCT05241392: Safety and Efficacy Study of Anti-B7-H3 CAR-T Cell Therapy for Recurrent Glioblastoma |
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| Recruiting | 1 | 30 | RoW | B7-H3-targeting CAR-T cells | Beijing Tiantan Hospital | Glioblastoma | 12/24 | 12/24 | | |
Hypo-Mag, NCT06760195: Intra-arterial Hypothermic Magnesium Sulfate Infusion in Combination with Endovascular Thrombectomy in Acute Ischemic Stroke |
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| Not yet recruiting | 1 | 6 | RoW | Intra-arterial hypothermic magnesium sulfate infusion, Endovascular thrombectomy, Intravenous thrombolysis | Capital Medical University | Acute Ischemic Stroke | 06/25 | 06/25 | | |
NCT05886205: Induced Pluripotent Stem Cell Derived Exosomes Nasal Drops for the Treatment of Refractory Focal Epilepsy |
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| Recruiting | 1 | 34 | RoW | iPSC-Exos | Peking Union Medical College Hospital, Guidon Pharmaceutics Ltd. | Refractory Focal Epilepsy | 06/25 | 11/25 | | |
NCT05447247: Clinical Study on Treatment of Neurogenic Bladder by Electroacupuncture on Ba Liao Point Under Ultrasound Guidance |
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| Recruiting | N/A | 114 | RoW | Acupuncturing Ba Liao point under ultrasound guidance | Qilu Hospital of Shandong University | To Investigate the Clinical Effect of Acupuncturing Ba Liao for Neurogenic Bladder Under the Guidance of Ultrasound | 10/23 | 12/23 | | |
AMITY, NCT06436677: A Study of Molecular Subtyping-based Therapeutic Strategies for Cutaneous T-cell Lymphoma |
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| Recruiting | N/A | 100 | RoW | molecular subtype based treatment | Peking University First Hospital, Peking University Third Hospital, Peking University Cancer Hospital & Institute | Cutaneous T-Cell Lymphoma/Mycosis Fungoides, Cutaneous T Cell Lymphoma | 12/26 | 12/30 | | |
| Wang, Qi |
NCT04201808: Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides |
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| Recruiting | 4 | 100 | RoW | Tenofovir Alafenamide 25 MG, Vemlidy | New Discovery LLC, Beijing Ditan Hospital | Hepatitis B, Chronic | 09/23 | 09/23 | | |
NCT05580354: Safety and Efficacy of BCG Combined With Tislelizumab for BCG-untreated Patients With High-risk Non-muscle Invasive Bladder Cancer |
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| Not yet recruiting | 4 | 42 | RoW | BCG combined with Tislelizumab | Ruijin Hospital | Non-muscle-invasive Bladder Cancer | 10/24 | 05/25 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
APPROACH, NCT04841811: MRD Guiding Treatment After Almonertinib Induction Therapy for EGFRm+ Stage III NSCLC in the MDT Diagnostic Model. |
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| Recruiting | 3 | 192 | RoW | Almonertinib, ctDNA dynamic monitoring guided the Almonertinib treatment | Guangdong Association of Clinical Trials, Jiangsu Hansoh Pharmaceutical Co., Ltd. | Lung Cancer | 12/24 | 12/26 | | |
NCT05470413: Evaluate the Efficacy and Safety of SHR0302 in Adult Patients With Severe Alopecia Areata |
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| Active, not recruiting | 3 | 330 | RoW | SHR0302, Placebo | Reistone Biopharma Company Limited | Alopecia Areata | 10/23 | 02/24 | | |
NCT05102149: Study to Evaluate the Safety and Efficacy of PB-201 in Treatment-naive Patients With Type 2 Diabetes Mellitus |
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| Recruiting | 3 | 672 | RoW | PB-201, Vildagliptin, PB-201 matched placebo, Vildagliptin matched placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 11/23 | 04/25 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
| Recruiting | 1 | 32 | RoW | chlorpromazine and promethazine, C+P, lytic cocktail, Placebo group, Control group, endovascular thrombectomy, rt-PA, Intravenous thrombolysis | Capital Medical University, Linyi People's Hospital | Acute Ischemic Stroke | 01/25 | 02/25 | | |
| Recruiting | N/A | 100000 | RoW | No intervention | Nanjing Jinling Hospital, Peking University, Sun Yat-sen University, Shandong University, Zunyi Medical College, Zhejiang University, Huazhong University of Science and Technology | Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects, Preterm Birth, Low Birth Weight, Pregnancy With Medical Condition (Non-Specific), Gestational Diabetes, Gestational Hypertension | 12/21 | 12/22 | | |
NCT02515474: Comparison of LCBDE vs ERCP + LC for Choledocholithiasis |
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| Completed | N/A | 1000 | RoW | Laparoscopy, Laparoscopic common bile duct exploration (LCBDE), Endoscopy, Endoscopic Retrograde cholangiopancreatography (ERCP) | Hepatopancreatobiliary Surgery Institute of Gansu Province | Choledocholithiasis | 01/24 | 01/24 | | |
NCT05947461: Prevention of Post-ERCP Pancreatitis by Indomethacin Vs Diclofenac |
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| Terminated | N/A | 1204 | RoW | 100mg diclofenac, 100mg indomethacin | Air Force Military Medical University, China | Post-ERCP Acute Pancreatitis, NSAIDs, Indomethacin, Diclofenac, Endoscopic Retrograde Cholangiopancreatography | 06/24 | 06/24 | | |
| Recruiting | N/A | 200 | RoW | Hematoporphyrin, ERCP stents | Hepatopancreatobiliary Surgery Institute of Gansu Province | Cholangiocarcinoma Non-resectable | 05/24 | 05/24 | | |
NCT06686134: Comprehensive Clinical Evaluation Study of GLP-1RA |
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| Recruiting | N/A | 492 | RoW | | LI YAN | T2DM | 12/25 | 07/26 | | |
NCT06777485: China Liver Cancer Clinical Registry Cohort Database |
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| Recruiting | N/A | 10000 | RoW | Procedure/Surgery treatment, Anti-Tumor Drugs | Anhui Provincial Hospital | Liver Cancer | 01/35 | 01/35 | | |
NCT06773221: The Efficacy and Safety of Chiglitazar in Patients with MAFLD-related Cirrhosis |
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| Not yet recruiting | N/A | 195 | RoW | Chiglitazar 64mg, Placebo | Beijing Friendship Hospital, Beijing Ditan Hospital, Peking University People's Hospital, Beijing YouAn Hospital | Metabolic Dysfunction Associated Fatty Liver Disease, Compensated Liver Cirrhosis | 01/28 | 06/28 | | |
| Not yet recruiting | N/A | 526 | NA | Ecological assessment and intervention, Audio-based Mindfulness intervention | The University of Hong Kong | Mindfulness | 07/25 | 12/25 | | |
| Recruiting | N/A | 10000 | RoW | Installation or registration of smartphone application | Chinese Alliance Against Lung Cancer | Solitary Pulmonary Nodule | 10/25 | 10/25 | | |
NCT06123858: Non-alcoholic Steatohepatitis Registry Platform Study |
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| Recruiting | N/A | 2500 | RoW | | AstraZeneca | NASH With Fibrosis | 12/26 | 12/26 | | |
NCT05947162: Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism |
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| Not yet recruiting | N/A | 150 | RoW | extinction training (nicotine cues), extinction training (neutral cues), Time-restricted smoking cessation, Time-restricted fasting, Dietary intervention, Time-restricted fasting with food supplemnet | Shenzhen Kangning Hospital | Tobacco Use Disorder | 07/27 | 07/27 | | |
| Not yet recruiting | N/A | 668 | RoW | Mindful yoga, Psychoeducation | The University of Hong Kong | Psychological | 03/28 | 09/28 | | |
NICCE, NCT05028231: Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study |
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| Recruiting | N/A | 46 | RoW | Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy | Tongji Hospital, National Natural Science Foundation of China | Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapies | 12/22 | 12/24 | | |
NCT05707585: Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage |
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| Recruiting | N/A | 2064 | RoW | Quantitative Chromogenic Imprinted Gene in situ Hybridization (QCIGISH) | The Second Affiliated Hospital of Dalian Medical University, Fudan University, Zongda Hospital affiliated to Southeast University, West China Hospital, Henan Provincial People's Hospital, First Hospital of China Medical University, Shengjing Hospital, The First Affiliated Hospital of Guangzhou Medical University, Lisen Imprinting Diagnostics, Inc. | Lung Cancer | 01/24 | 07/24 | | |
| Song, Lei |
UltraFuture I, NCT05498740: Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia |
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| Recruiting | N/A | 200 | RoW | Drug eluting Balloon | Zhejiang Zylox Medical Device Co., Ltd. | Peripheral Arterial Disease (PAD) | 12/22 | 12/24 | | |
NCT06391788: Efficacy and Safety of Thoracoscopic Morrow Surgery in the Treatment of Hypertrophic Obstructive Cardiomyopathy |
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| Recruiting | N/A | 132 | RoW | thoracoscopic Morrow surgery, modified Morrow surgery | China National Center for Cardiovascular Diseases | Cardiomyopathy, Hypertrophic Obstructive, Minimally Invasive Surgery | 02/25 | 03/25 | | |
NCT06512571: CVI Alterations in FD: a Prospective, Multicenter, Observational Cohort Study |
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| Not yet recruiting | N/A | 300 | RoW | | China National Center for Cardiovascular Diseases | Fabry Disease, Cardiac Variant | 07/26 | 07/26 | | |
NCT03356236: Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation |
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| Recruiting | N/A | 828 | RoW | | Yue Han | Hepatocarcinoma | 08/24 | 12/24 | | |
| Not yet recruiting | N/A | 500 | RoW | Assessment of plaque morphology, structure, and stability in non-culprit lesions | Chinese PLA General Hospital | Coronary Arterial Disease (CAD), Acute Coronary Syndromes | 12/27 | 12/31 | | |
| Active, not recruiting | N/A | 5000 | RoW | | China National Center for Cardiovascular Diseases | Coronary Heart Disease, Chronic Total Occlusion of Coronary Artery, Percutaneous Coronary Intervention, Intravascular Ultrasound | 12/24 | 12/25 | | |
| Recruiting | N/A | 125 | RoW | | China National Center for Cardiovascular Diseases | Coronary Artery Disease Progression, Radial Wall Strain, Atherosclerotic Lesion, Optical Coherence Tomography | 06/25 | 12/26 | | |
| Not yet recruiting | N/A | 5000 | NA | FAST Technique, The next-generation quantitative flow ratio and radial wall strain, Angiography, Coronary angiography | China National Center for Cardiovascular Diseases | ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease, Percutaneous Coronary Intervention | 06/25 | 06/28 | | |
| Not yet recruiting | N/A | 20000 | RoW | | China National Center for Cardiovascular Diseases | Cardiovascular Diseases | 10/25 | 10/30 | | |
| Recruiting | N/A | 3000 | RoW | | China National Center for Cardiovascular Diseases | Cardiomyopathy, Hypertrophic | 12/25 | 12/28 | | |
| Qu, Peng |
HEARTRIP, NCT03809273: Effects of Yangxinshi Pills on the Exercise Tolerance Compared With Trimetazidine in Patients After PCI |
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| Recruiting | 4 | 668 | RoW | Yangxinshi, Trimetazidine, Yangxinshi mimic, Trimetazidine mimic | Shenyang Northern Hospital | Percutaneous Coronary Intervention | 12/20 | 12/20 | | |
| Recruiting | N/A | 4500 | RoW | | Harbin Medical University, Abbott | Acute Myocardial Infarction | 07/21 | 12/22 | | |
NCT04569669: The Sensitivity and Specificity of CardioSimFFRct Analysis Software on Coronary Artery Stenosis |
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| Not yet recruiting | N/A | 325 | RoW | FFR and FFRCT | CCRF Inc., Beijing, China, Shengshi Technology, Co., Ltd, Hangzhou, China | Coronary Stenosis | 10/21 | 03/22 | | |
NCT05862103: Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort |
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| Recruiting | N/A | 15000 | RoW | Treatment Strategies | Yu Bo | Acute Myocardial Infarction, Adverse Event | 08/25 | 12/26 | | |
| Wu, Jun |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
| Recruiting | N/A | 3500 | RoW | | Tang-Du Hospital, Esaote (Shenzhen) Medical Equipment Co. Ltd, The First Affiliated Hospital, Zhejiang University School of Medicine, Shannxi Provincial People's Hospital, Shengjing Hospital, First Hospital of China Medical University, Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Renmin Hospital of Wuhan University, Beijing University of Chinese Medicine Third Affiliated Hospital, The First Affiliated Hospital of Shanxi Medical University, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, The First Hospital of Jilin University, The Afffiliated Hospital of Guizhou Medical University, Yan An Hospital Affiliated to Kunming Medical University, Second Affiliated Hospital of Guangzhou Medical University, Third Xiangya Hospital of Central South University, Ruijin Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Anhui Medical University, The Second Hospital of Anhui Medical University, The First Affiliated Hospital of USTC, The Affiliated Hospital of Qingdao University, First Affiliated Hospital of Xinjiang Medical University, Hospital of Northwestern Polytechnical University, GEM Flower Xian Changqing Staff Hospital, Xi'an Central Hospital, The Second Affiliated Hospital of Xi'an Medical University, Second Affiliated Hospital of Xi'an Jiaotong University, First Affiliated Hospital of Guangxi Medical University, Karamay Central Hospital of Xinjiang, The Fourth Affiliated Hospital of Xinjiang Medical University, Xi'an No.1 Hospital, Xianyang Hospital of Yan'an University, General Hospital of Xinjiang Production and Construction Corps, Air Force Medical Center | Healthy, Adults, Carotid Intima-media Thickness, Vascular Stiffness, Chinese | 05/22 | 05/22 | | |
NCT05975398: China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH） |
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| Recruiting | N/A | 450 | RoW | Emergency neurosurgery, Conservative treatment | Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Beijing Shuyi Hospital, Beijing Anzhen Hospital, Guangzhou Red Cross Hospital, Beijing Pinggu District Hospital, Beijing Friendship Hospital, Wuxi No. 2 People's Hospital, Dezhou People's Hospital, Binzhou People's Hospital | Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications | 06/25 | 12/25 | | |
NCT04820972: Early-Start Antiplatelet Treatment After Neurosurgery in Patients With Spontaneous Intracerebral Hemorrhage |
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| Recruiting | N/A | 250 | RoW | Antiplatelet Agents | Beijing Tiantan Hospital, The Second Affiliated Hospital of Kunming Medical University, First Affiliated Hospital of Fujian Medical University, The Second Xiangya Hospital of Central South Medical University, First Affiliated Hospital of Harbin Medical University, Gangzhou Red Cross Hospital ，Jinan University, Beijing Chao Yang Hospital, RenJi Hospital, Sichuan Academy of Medical Sciences, Chongqing General Hospital, Binzhou Medical University, Fujian Medical University Union Hospital, Shanxi Provincial People Hospital, Beijing Friendship Hospital, Qilu Hospital of Shandong University, Second Affiliated Hospital, School of Medicine, Zhejiang University | Spontaneous Intracerebral Hemorrhage | 02/23 | 05/23 | | |
NCT06214767: Study on Treatment Decision-Making and Prognostic Follow-Up for Untreated Cerebral Cavernous Malformations |
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| Recruiting | N/A | 1200 | RoW | | Beijing Tiantan Hospital, RenJi Hospital, Beijing Chao Yang Hospital, Beijing Friendship Hospital, Guangzhou Red Cross Hospital, Affiliated Hospital of Guangdong Medical University, Shanxi Provincipal People's Hospital, Qilu Hospital of Shandong University, Central South University, First Affiliated Hospital of Harbin Medical University | Hemangioma, Cavernous, Central Nervous System | 12/25 | 06/26 | | |
NCT06185465: Effectiveness and Safety of Using Prontosan to Treat Bacterial Biofilm |
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| Recruiting | N/A | 60 | RoW | Prontosan Wound Irrigation Solution, Debridement surgery, Normal Saline | The First Hospital of Jilin University, Shenzhen Second People's Hospital, Fujian Medical University Union Hospital | Irrigation Solution, Chronic Wound, Pressure Injury, Diabetic Foot Ulcer, Burns | 02/24 | 02/25 | | |
NCT06249087: Multifunctional Nutrition Tube on Social Condition and Experience in Cerebralvascular Accident |
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| Recruiting | N/A | 80 | RoW | comprehensive rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric Tube Feeding | Zeng Changhao | Stroke | 05/24 | 05/24 | | |
NCT06248892: The Effect of Oral and Nasal Feeding on Cerebral Small Vessel Disease |
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| Recruiting | N/A | 88 | RoW | Nasogastric Tube Feeding, Intermittent Oro-esophageal Tube Feeding, comprehensive rehabilitation therapy | Zeng Changhao | Cerebral Small Vessel Diseases | 04/24 | 05/24 | | |
NCT06249425: Transcranial Direct Current Stimulation Combined With Oral Feeding on Dysphagia |
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| Recruiting | N/A | 80 | RoW | Comprehensive rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Transcranial direct current stimulation | Zeng Changhao | Stroke | 05/24 | 05/24 | | |
NCT06255353: Effect of Different Feeding Modes in Intracerebral Hemorrhage |
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| Recruiting | N/A | 120 | RoW | Intermittent Oro-esophageal Tube Feeding, Basic treatment, Nasogastric Tube Feeding | Zeng Changhao | Intracerebral Hemorrhage | 06/24 | 06/24 | | |
NCT06248879: Intermittent Oro-esophageal Tube Feeding in Late Dysphagia for Nasopharyngeal Carcinoma |
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| Withdrawn | N/A | 80 | RoW | Intermittent Oral-esophageal Tube Feeding, Nasogastric Tube Feeding, comprehensive rehabilitation therapy | People's Hospital of Zhengzhou University | Dysphagia | 04/24 | 04/24 | | |
NCT06249490: Stellate Ganglion Block in Obstructive Sleep Apnea |
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| Recruiting | N/A | 80 | RoW | routine rehabilitation treatment, Stellate ganglion block, Lidocaine Hydrochloride Injection, Lidocaine Hydrochloride | Zeng Changhao | Obstructive Sleep Apnea | 05/24 | 05/24 | | |
NCT06256861: Effect of Myofascial Release on Dysphagia in Patients With Traumatic Brain Injury |
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| Recruiting | N/A | 80 | RoW | Rehabilitation treatment, Myofascial Release Therapy | Zeng Changhao | Traumatic Brain Injury | 05/24 | 05/24 | | |
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes |
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| Recruiting | N/A | 10168 | RoW | Continuous glucose monitoring (CGM) device | Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital | Comprehensive Complication Index | 10/25 | 12/25 | | |
ChTUIA, NCT05844163: Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment Trial for Unruptured Intracranial Aneurysm |
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| Recruiting | N/A | 21041 | RoW | observation | Beijing Tiantan Hospital, Huashan Hospital, The First Affiliated Hospital of Zhengzhou University, First Affiliated Hospital of Fujian Medical University, Shanxi Provincial People's Hospital | Unruptured Intracranial Aneurysm | 12/24 | 12/24 | | |
NCT05941377: Enhanced Versus Standard Blood Pressure Lowering on Intracranial Aneurysm Rupture or Growth China Antihypertensive Trial for Intracranial Aneurysm (ChATIA-1) |
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| Recruiting | N/A | 520 | RoW | blood pressure lowering | Beijing Tiantan Hospital, Shanghai Jiaotong University School of Medicine,Renji Hospital, Guangzhou Red Cross Hospital, Jiangnan University Medical Center, The First Dongguan Affiliated Hospital of Guangdong Medical University | Unruptured Intracranial Aneurysm | 07/25 | 07/26 | | |
AIM, NCT05032053: Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | N/A | 3000 | RoW | Antithrombotic drugs | Xijing Hospital, Ankang Central Hospital, Yan'an University Affiliated Hospital | Ischemic Stroke | 12/25 | 10/26 | | |
| Jiang, Kui |
NCT05622890: A Single-arm Clinical Trial of IMGN853 in Chinese Adult Patients With Platinum-resistant, Epithelial Ovarian Cancer |
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| Recruiting | 3 | 35 | RoW | Mirvetuximab Soravtansine, IMGN853, MIRV | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Epithelial Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer | 04/23 | 12/23 | | |
| Active, not recruiting | 3 | 502 | Europe, Canada, Japan, US, RoW | tisotumab vedotin, TIVDAK, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed | Seagen Inc., Genmab | Cervical Cancer | 07/23 | 08/25 | | |
| Not yet recruiting | 3 | 416 | RoW | paclitaxel polymeric micelles for injection, Gemcitabine Hydrochloride for Injection, Paclitaxel for Injection (albumin bound ) | Shanghai Yizhong Pharmaceutical Co., Ltd. | Pancreatic Cancer Metastatic | 07/27 | 12/27 | | |
NCT05033132: A Phase II Study of Balstilimab Independently or in Combination With Zalifrelimab in Advanced Cervical Cancer |
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| Withdrawn | 2 | 177 | RoW | Balstilimab, Balstilimab + Zalifrelimab | Agenus Inc., Betta Pharmaceuticals Co., Ltd. | Cervical Cancer | 12/24 | 12/24 | | |
| Recruiting | 2 | 240 | Europe, Canada, US, RoW | SKB264, Pembrolizumab, Keytruda | Klus Pharma Inc., Myriad Genetics, Inc., Discovery Life Sciences, LLC, Ventana Medical Systems, Inc, Frontage Laboratories, Inc. | Solid Tumor | 11/26 | 12/27 | | |
KL264-01, NCT04152499: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies |
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| Recruiting | 1/2 | 1300 | Canada, US, RoW | SKB264 | Klus Pharma Inc. | Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer | 08/25 | 07/26 | | |
| Li, Man |
CLOVER, NCT03926091: Study Comparing 4 Cycles With 6 Cycles of TC (Docetaxel+Cyclophosphamide) Adjuvant Chemotherapy for 1-3 Lymph Node Positive ER+/HER2- Early Breast Cancer |
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| Recruiting | 3 | 2172 | RoW | Docetaxel, docetaxel injection, Cyclophosphamide, Cyclophosphamide injection | Fudan University | Breast Cancer | 11/24 | 11/25 | | |
TQB2450-III-07, NCT04523272: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Sunitinib in Subjects With Advanced Renal Cancer |
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| Active, not recruiting | 3 | 528 | RoW | TQB2450, Anlotinib, Sunitinib | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Renal Cancer | 06/25 | 12/25 | | |
TORCHLIGHT, NCT04085276: Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment |
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| Active, not recruiting | 3 | 531 | RoW | JS001, Nab-Paclitaxel, Placebo | Shanghai Junshi Bioscience Co., Ltd. | Triple-Negative Breast Cancer | 12/24 | 12/25 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
