| Greenwood, John P |
| Completed | 2 | 49 | Europe | PROTHERACYTES, Standard Treatment for CHF post AMI | CellProthera | Acute Myocardial Infarction | 03/24 | 03/24 | | |
MicroRESUS, NCT05330676: Evaluation of Microcirculatory Function and Mitochondrial Respiration After Cardiovascular Surgery |
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| Completed | N/A | 142 | US | coronary artery bypass grafting, valve repair/replacement | University of Pennsylvania, National Center for Advancing Translational Sciences (NCATS) | Shock, Cardiovascular Diseases, Critical Illness | 04/23 | 04/23 | | |
| Active, not recruiting | N/A | 807 | Europe | IVUS guided Percutaneous Coronary Intervention, QCA guided Percutaneous Coronary Intervention | ECRI bv, Philips Healthcare, Boston Scientific Corporation | Left Main Coronary Artery Stenosis | 07/25 | 07/25 | | |
| Recruiting | N/A | 1800 | US | Therapeutic Hypothermia | University of Michigan, Johns Hopkins University, Medical University of South Carolina, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) | Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain | 07/28 | 08/28 | | |
BRITISH, NCT05568069: RCT of Implantable Defibrillators in Patients with Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure |
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| Recruiting | N/A | 2504 | Europe | Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD) | University Hospital Southampton NHS Foundation Trust, British Heart Foundation, University of Southampton | Heart Failure | 04/26 | 04/36 | | |
| Recruiting | N/A | 2000 | Europe | Part 1: DCM Cohort, Whole genome sequencing and biomarker analysis, Part 2: Heritable CV Diseases and Family Members, Biomarker analysis | Imperial College London, British Heart Foundation, Royal Brompton & Harefield NHS Foundation Trust | Dilated Cardiomyopathy, Cardiovascular Diseases | 07/27 | 07/27 | | |
| Shafeek, Salim |
| Recruiting | 3 | 740 | Europe | R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - reactive arm, Ninlaro, Revlimid, R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - adaptive arm, R2: Lenalidomide plus placebo maintenance, R2: Lenalidomide + ixazomib maintenance | University of Leeds, Cancer Research UK, Takeda, Celgene | Multiple Myeloma | 12/24 | 12/24 | | |
| Nyamekye, Isaac K |
DAVE, NCT04021316: Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration |
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| Terminated | N/A | 71 | Europe | dCELL® Human Dermis (decellularised dermal skin allograft - DCD), Compression bandaging therapy | Imperial College London, University of Edinburgh, Universidad de Granada, University of Manchester, Gloucestershire Hospitals NHS Foundation Trust, Cambridge University Hospitals NHS Foundation Trust, University of Birmingham, NHS Blood and Transplant | Venous Ulcer, Allograft | 04/23 | 04/23 | | |
DM PAD, NCT05009602: Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes |
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| Active, not recruiting | N/A | 604 | Europe | Toe Brachial Pressure Index (TBPI), Ankle Brachial Pressure Index (ABPI), Exercise Ankle Brachial Pressure Index (ABPI), Audible handheld Doppler, Visual handheld Doppler, Podiatry Ankle Duplex scan (PAD-scan) | Imperial College London, University of Leicester, University of Edinburgh, Universidad de Granada | Diabetic Foot, Peripheral Arterial Disease, Diabetic Foot Ulcer, Peripheral Vascular Diseases, Peripheral Artery Disease, Critical Limb Ischemia, Critical Lower Limb Ischemia | 02/24 | 02/24 | | |
| Shafik, Saleem |
ACCoRd, NCT03562169: The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII |
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| Recruiting | 3 | 406 | Europe | Ixazomib, thalidomide, & dexamethasone (ITD) re-induction, Conventional autologous stem cell transplant (ASCT-con), Augmented autologous stem cell transplant (ASCT-aug), ITD consolidation and ixazomib maintenance vs. No further therapy | University of Leeds, Cancer Research UK, Takeda | Multiple Myeloma | 03/26 | 03/27 | | |
| Chan, Cheuk Yin |
BRITISH, NCT05568069: RCT of Implantable Defibrillators in Patients with Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure |
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| Recruiting | N/A | 2504 | Europe | Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD) | University Hospital Southampton NHS Foundation Trust, British Heart Foundation, University of Southampton | Heart Failure | 04/26 | 04/36 | | |
| Recruiting | N/A | 2600 | Europe | Pacemaker - Physiological pacing, Pacemaker - Right Ventricular pacing | Imperial College London, British Heart Foundation | Bradycardia, Pacing, Right Ventricular Pacing, His Bundle Pacing, Left Bundle Branch Area Pacing | 12/29 | 12/29 | | |
| Trevelyan, Jasper |
| Active, not recruiting | N/A | 3326 | Europe, RoW | SELUTION SLR, DES | M.A. Med Alliance S.A. | Coronary Artery Disease | 08/25 | 07/30 | | |
| Arya, Anita |
| Active, not recruiting | N/A | 965 | Europe, US | ommitence of defibrillation testing | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boston Scientific Corporation | Ventricular Arrythmia | 04/25 | 07/25 | | |
BRITISH, NCT05568069: RCT of Implantable Defibrillators in Patients with Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure |
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| Recruiting | N/A | 2504 | Europe | Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD) | University Hospital Southampton NHS Foundation Trust, British Heart Foundation, University of Southampton | Heart Failure | 04/26 | 04/36 | | |
| O'Hickey, Stephen |
| Recruiting | N/A | 250 | Europe | Optional Bronchoscopy, Quality of Life Questionnaires, Blood Samples for Biomarkers, Home Hand Held Spirometry | University of Nottingham, Nottingham University Hospitals NHS Trust | Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis | 11/22 | 11/22 | | |
| Routledge, Helen |
| Recruiting | N/A | 3000 | Europe | Ultimaster Nagomi™ | Terumo Europe N.V. | Cardiovascular Disease, Coronary Artery Occlusion, Ischemic Heart Disease | 09/26 | 09/27 | | |
| Trevelyan |
| Active, not recruiting | 3 | 9541 | Europe, Canada, Japan, US, RoW | Obicetrapib, Placebo | NewAmsterdam Pharma, Monash University | Atherosclerotic Cardiovascular Disease | 11/26 | 11/26 | | |
| Contact, First |
PARTNER, NCT03150576: Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer |
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| Recruiting | 2/3 | 780 | Europe | Olaparib, Lynparza, Paclitaxel and Carboplatin, Taxol and Paraplatin | Cambridge University Hospitals NHS Foundation Trust, AstraZeneca, Cancer Research UK | Breast Cancer | 06/24 | 06/34 | | |
| Churn, Mark |
| Recruiting | 3 | 2032 | Europe | Abemaciclib, Verzenios, Endocrine therapy (letrozole, anastrozole, exemestane or tamoxifen), Arimidex, Aromasin, Femara, or Tamoxifen | Institute of Cancer Research, United Kingdom | Breast Cancer Female | 09/30 | 03/32 | | |
PARTNER, NCT03150576: Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer |
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| Recruiting | 2/3 | 780 | Europe | Olaparib, Lynparza, Paclitaxel and Carboplatin, Taxol and Paraplatin | Cambridge University Hospitals NHS Foundation Trust, AstraZeneca, Cancer Research UK | Breast Cancer | 06/24 | 06/34 | | |
| Romanova, Janina |
| Active, not recruiting | 3 | 9541 | Europe, Canada, Japan, US, RoW | Obicetrapib, Placebo | NewAmsterdam Pharma, Monash University | Atherosclerotic Cardiovascular Disease | 11/26 | 11/26 | | |
