| Christ-Crain, Mirjam |
OxyMOTION, NCT06676774: Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls |
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| Not yet recruiting | 2 | 42 | Europe | Oxytocin nasal spray, Placebo | University Hospital, Basel, Switzerland | Arginine Vasopressin Deficiency, Diabetes Insipidus | 01/27 | 01/27 | | |
OxyPLEASURE, NCT06808516: Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls |
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| Not yet recruiting | 2 | 42 | Europe | Oxytocin nasal spray, Syntocinon, Placebo | University Hospital, Basel, Switzerland | Arginine Vasopressin Deficiency, Central Diabetes Insipidus, Oxytocin Deficiency | 12/26 | 12/26 | | |
| Recruiting | 2 | 112 | Europe | Intranasal OXT, Placebo nasal spray | University Hospital, Basel, Switzerland | Central Diabetes Insipidus (cDI) | 10/26 | 10/26 | | |
BONA, NCT04227301: Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients |
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| Recruiting | N/A | 52 | Europe | blood sampling | University Hospital, Basel, Switzerland | Hyponatremia | 10/25 | 10/25 | | |
TREASURE, NCT04987385: Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD |
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| Completed | N/A | 18 | Europe | Protein supplementation, Oral urea | University Hospital, Basel, Switzerland | Syndrome of Inappropriate Antidiuresis (SIAD) | 02/23 | 02/23 | | |
NCT03557957: Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia |
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| Active, not recruiting | N/A | 2278 | Europe, RoW | Targeted correction of plasma sodium levels, Standard care | University Hospital, Basel, Switzerland, Erasmus Medical Center, Cantonal Hospital of Aarau, Switzerland, Spital Solothurn, Switzerland, Kantonsspital St. Gallen, Switzerland, Kantonsspital Liestal, Switzerland, Uniklinik Köln, Germany, KBC Zagreb, Croatia, Azienda Ospedaliero Universitaria Careggi, Italy | Hyponatremia | 04/25 | 04/25 | | |
ESCAPE, NCT06277336: Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD |
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| Recruiting | N/A | 20 | Europe | Placebo, Apelin Low Dose, Apelin High Dose, Selected Apelin Dose | University Hospital, Basel, Switzerland | SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia | 12/24 | 12/25 | | |
NCT06381934: Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics |
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| Recruiting | N/A | 136 | Europe | Standard Care, aSID/ChU Guided Therapy | University Hospital, Basel, Switzerland | Thiazide Associated Hyponatremia | 04/27 | 04/27 | | |
MARS, NCT06542198: Mannitol-induced Release of Copeptin in Healthy Adults and Patients With Polyuria-Polydipsia Syndrome ( Study) |
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| Recruiting | N/A | 42 | Europe | Mannitol Infusion (blinded), Placebo Infusion (blinded), Mannitol Infusion (open label) | University Hospital, Basel, Switzerland | Polyuria-polydipsia Syndrome, Arginine Vasopressin Deficiency, Primary Polydipsia | 12/25 | 12/25 | | |
URANOS, NCT05890690: Plasma Copeptin in Response to Oral Urea in Healthy Adults and Patients With Polyuria-polydipsia Syndrome |
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| Completed | N/A | 48 | Europe | Urea, Placebo | University Hospital, Basel, Switzerland | Arginine Vasopressin Deficiency, Primary Polydipsia | 06/24 | 06/24 | | |
PROPHECY, NCT05542056: Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia |
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| Recruiting | N/A | 232 | Europe | Data and biosample collection | University Hospital, Basel, Switzerland | Thiazide-induced Hyponatremia (TIH) | 04/25 | 04/25 | | |
| Recruiting | N/A | 1800 | Europe | Statin discontinuation, Intervention arm | Insel Gruppe AG, University Hospital Bern, University of Bern | Statin Treatment for Primary Prevention | 11/26 | 11/26 | | |
