University of Palermo Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Giordano, Carla

SURPASS-EARLY, NCT05433584: A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

Active, not recruiting

780

Europe, Canada, US, RoW

Tirzepatide, LY3298176, Antihyperglycemic medication

Eli Lilly and Company

Type 2 Diabetes

10/25

11/27

NCT04628481 / 2020-001926-71: A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Active, not recruiting

140

Europe, US, RoW

Ladarixin, allosteric inhibitor of CXCL8 (IL-8), CXCR1 and CXCR2 receptors, Placebo

Dompé Farmaceutici S.p.A, Dompe farmaceutici s.p.a.

Recent Onset type1 Diabetes

04/24

04/26

PHOTOFINISH, NCT05613985: a Clinical Study To Evaluate The Efficacy And Safety Of the System VULNOFAST® Plus/VULNOLIGHT® In Addition To The Usual Care (UC) Vs UC Alone For The Treatment Of Infected Diabetic Foot Ulcers

Recruiting

N/A

146

Europe

Usual Care alone, System VULNOFAST® plus / VULNOLIGHT® in addition to Usual Care

L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A.

Diabetic Foot Infection

06/24

12/24

MITRA, Maria Enza

AMELIORATE, NCT04174612 / 2019-003936-21: AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance

Recruiting

172

Europe

Cytarabine, Daunorubicin, Midostaurin, Cytarabine HD

Gruppo Italiano Malattie EMatologiche dell'Adulto, MYNERVA (MYeloid Neoplasms Research Venture AIRC) programma speciale finanziato dall'AIRC - Associazione Italiana per la, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus

Acute Myeloid Leukemia With FLT3/ITD Mutation

12/22

08/25

NCT04168502 / 2019-003871-20: Gemtuzumab Chemotherapy MRD Levels; Adult Untreated, de Novo, Fav Interm Risk AML

Recruiting

414

Europe

Gemtuzumab Ozogamicin

Gruppo Italiano Malattie EMatologiche dell'Adulto, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus, Pfizer S.R.L.

Acute Myeloid Leukemia

04/25

04/27

1621-QLG-LG, NCT03755856: Long-term Outcomes for Acute Myeloid Leukemia Patients

Recruiting

N/A

343

Europe, RoW

Questionnaire

Gruppo Italiano Malattie EMatologiche dell'Adulto, European Organisation for Research and Treatment of Cancer - EORTC

Acute Myeloid Leukemia

06/21

12/22

NCT04460950: Observational Study for the Evaluation of Incidence of Familial AML/MDSs in Patients With Myeloid Neoplasms

Recruiting

N/A

237

Europe

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Myeloid Leukemia, Familial Acute Myeloid Leukemia, Myelodysplastic Syndromes

03/25

NCT05934084: Lifestyles Implemented-Survivorship Care Plan in Lymphoma Survivors

Recruiting

N/A

552

Europe

Lifestyles Implemented-Survivorship Care Plan (LS-SCP)

Fondazione Italiana Linfomi - ETS

Classical Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL)

02/26

Napolitano, Mariasanta

INTHEMA, NCT04298892: Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies

Recruiting

N/A

2000

Europe

clinical data and sample collection

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori, Azienda Unità Sanitaria Locale della Romagna

Haematologic Disease, Haematological Malignancy

02/25

Badalamenti, Giuseppe

METROPHOLYS, NCT04656262 / 2018-001075-20: Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients

Terminated

Europe

Cyclophosphamide, Endoxan, Doxorubicin

Istituto Oncologico Veneto IRCCS, Ministry of Health, Italy

Soft Tissue Sarcoma Adult

05/24

TANGENT, NCT05417789: Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)

Recruiting

128

Europe, Canada, US, RoW

Emactuzumab, Placebo

SynOx Therapeutics Limited

TGCT

04/26

09/27

STRADA, NCT03023124 / 2016-004051-78: Study With Trabectedin Versus Adriamycin Plus Dacarbazine, in Patients With Advanced Solitary Fibrous Tumor

Completed

Europe

Trabectedin, Adriamycin, Dacarbazine

Italian Sarcoma Group

Solitary Fibrous Tumors

12/24

ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma

Recruiting

201

Europe, US, RoW

INBRX-109, Placebo

Inhibrx Biosciences, Inc

Conventional Chondrosarcoma

09/25

12/26

ERASING, NCT03840772 / 2018-004571-12: Eribulin in Advanced Solitary Fibrous Tumor

Completed

Europe

Eribulin, Intervention under investigation

Italian Sarcoma Group, Eisai Inc.

Solitary Fibrous Tumor

09/24

ACCeSs, NCT04274023 / 2016-004368-21: Study on TSR-042 in Advanced Clear Cell Sarcoma

Terminated

Europe

TSR-042

Italian Sarcoma Group, GlaxoSmithKline

Sarcoma, Clear Cell

01/24

ISG-MCS, NCT04305548 / 2019-003733-41: Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma

Recruiting

Europe

Trabectedin

Italian Sarcoma Group, PharmaMar

Mesenchymal Chondrosarcoma

08/25

12/25

TOMAS2, NCT03838744 / 2018-004497-10: Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.

Completed

130

Europe

Standard arm: Trabectedin in monotherapy, Trabectedin arm, Experimental arm: Trabectedin + Olaparib, Trabectedin+ Olaparib arm

Italian Sarcoma Group, PharmaMar, AstraZeneca

Advanced Soft Tissue Sarcoma

11/24

Breast-Sarc, NCT04749446: Study on Clinical Features and Outcomes of Breast Sarcoma

Recruiting

N/A

300

Europe

Treatment of Breast Sarcoma according clinical practice (includes drugs, surgery or any other received treatments)

Italian Sarcoma Group

Breast Sarcoma

12/25

EHE, NCT06408441: The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)

Recruiting

N/A

100

Europe

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, EHE Rare Cancer Charity UK

Epithelioid Hemangioendothelioma, Sarcoma,Soft Tissue

12/33

NCT04282083: Protocol ITANET - Registry

Recruiting

N/A

3600

Europe

Italian Association Neuroendocrine Tumors

Gastro-entero Pancreatic Neuroendocrine Tumors

07/27

07/32

LaganÃ , Antonio Simone

NCT05771415: Near-infrared Spectroscopy: Differences in Placental Oxygenation in Relation to Ultrasound Maturation Grade in physiologIcal Term Pregnancies

Completed

N/A

RoW

University of Palermo

Placenta Diseases

01/21

02/21

NCT04030273: Prevalence of Intrauterine Adhesions After Abdominal Myomectomy

Not yet recruiting

N/A

150

Diagnostic hysteroscopy

Università degli Studi dell'Insubria, University of Miami

Myoma;Uterus

01/23

01/24

NCT05812937: Intraoperative Intraabdominal Ultrasound for Endometriosis

Recruiting

N/A

Europe

Intraabdominal ultrasound, Laparoscopic visualization, Laparoscopic palpation, Direct palpation in case of a conventional segmental bowel resection with specimen extraction per minilaparotomy.

University of Palermo

Endometriosis, Endometriosis; Bowel, Ultrasound Therapy; Complications

01/23

12/23

NCT05755529: Effects of Low LH Serum Levels on Ovarian Pick-up Outcome

Not yet recruiting

N/A

University of Palermo

Infertility, Female, ART

03/23

NCT05791838: Experience in Borderline Ovarian Tumors

Not yet recruiting

N/A

University of Palermo

Borderline Ovarian Tumor

03/23

OUTSET-1, NCT03439956: Obstetric Outcomes After Transvaginal Specimen Extraction in Gynecological Laparoscopy

Not yet recruiting

N/A

200

Transvaginal specimen extraction

Università degli Studi dell'Insubria

Pregnancy Complications, Delivery;Abnormal;Stillbirth

04/23

04/24

ENCA-1, NCT03570866: PET/CT in the Management of Patients With Early Stage Endometrial Cancer

Not yet recruiting

N/A

Positron emission tomography and computed tomography, Surgical treatment

Università degli Studi dell'Insubria, Universita di Verona

Endometrium Cancer

05/23

05/24

IRE-1, NCT03565848: Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis

Not yet recruiting

N/A

Mesenteric vascular and nerve sparing surgery in laparoscopic segmental colorectal resection

Università degli Studi dell'Insubria

Endometriosis, Bowel Endometriosis, Constipation

05/23

05/24

LULS-1, NCT03553511: Laparoscopic Hysterectomy With Vaginal Vault Suspension to the Uterosacral Ligaments for Stage II-III Pelvic Organ Prolapse.

Not yet recruiting

N/A

Vaginal vault suspension to the uterosacral ligaments, McCall culdoplasty

Università degli Studi dell'Insubria

Pelvic Organ Prolapse

05/23

05/24

MYMOTE-1, NCT03570879: Laparoscopic Myomectomy With Morcellation or Transvaginal Extraction of Surgical Specimens.

Not yet recruiting

N/A

250

Power morcellation, Transvaginal extraction

Università degli Studi dell'Insubria

Myoma;Uterus

05/23

05/24

IROP-1, NCT03598374: Spontaneous Reproductive Outcomes After Oral Inositol Supplementation in Infertile Polycystic Ovarian Syndrome Women.

Not yet recruiting

N/A

Inositol + Folic acid, Folic acid, Regular intercourses

Università degli Studi dell'Insubria, Universita di Verona

Polycystic Ovarian Syndrome, Infertility, Female

06/23

12/24

LPTM-UFs-P, NCT06009562: Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study

Recruiting

N/A

RoW

Laparotomic myomectomy during pregnancy

University of Palermo

Uterine Fibroid, Pregnancy Related

08/23

01/24

ENDO-DCI, NCT06314126: Evaluation of D-Chiro-Inositol Treatment in Women With Endometriosis

Recruiting

N/A

Europe

D-Chiro-Inositol, Placebo

University of Palermo

Endometriosis

01/25

04/25

EGCG-HPV, NCT06314113: Evaluation of Oral EGCG Treatment for L-SIL Associated With HPV Infection

Recruiting

N/A

Europe

Epigallocatechin Gallate

University of Palermo

Low-Grade Intraepithelial Neoplasia of Cervix

03/25

09/25

IPOSI-1, NCT03585738: Effects of Oral Inositol Supplementation on Obstetrics Outcomes in PCOS Women

Not yet recruiting

N/A

Inositol + Folic acid, Folic acid

Università degli Studi dell'Insubria, Universita di Verona

Polycystic Ovary Syndrome

12/24

12/26

DUS-1, NCT04075786: Survey of Dysmorphic Uterus Knowledge Among Gynecologists.

Not yet recruiting

N/A

300

Survey

UniversitÃ degli Studi dell'Insubria, University of Miami

Dysmorphic Uterus

03/25

04/27

SOAVE-1, NCT03788720: Suture of the Ovary After Enucleation of Ovarian Endometrioma

Not yet recruiting

N/A

100

Europe

Suture of the ovarian cortex, No suture of the ovarian cortex

Università degli Studi dell'Insubria

Endometrioma

05/25

05/27

FSF-TVE, NCT03838302: Evaluation of Sexual Functions With Validated Measurement Scale After Transvaginal Extraction of Tissue by Laparoscopic Surgery With Uterus Preservation

Not yet recruiting

N/A

Europe

Transvaginal tissue retrieval via a posterior colpotomy, Transabdominal retrieval via trocar

Università degli Studi dell'Insubria

Transvaginal Tissue Extraction

06/25

06/27

NCT03717870: Surgery and ART For Endometrioma

Not yet recruiting

N/A

100

Laparoscopic enucleation of ovarian endometrioma., Prolonged pituitary downregulation, Assisted Reproductive Technology (ART)

Università degli Studi dell'Insubria

Ovarian Endometrioma, Infertility, Female

10/25

10/27

LAST-1, NCT05421156: Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy

Not yet recruiting

N/A

100

Subtotal Laparoscopic Hysterectomy, Total Laparoscopic Hysterectomy

University of Palermo

Hysterectomy

07/26

07/28

NCT05271877: Evaluation of Surgical and Obstetric Outcomes in Pregnant Women Undergoing Operative Laparoscopy

Not yet recruiting

N/A

100

Laparoscopy

Università degli Studi dell'Insubria

Pregnancy Related, Laparoscopy

12/23

12/24

Tuttolomondo, Antonino

PERIDOT, NCT05206773 / 2021-002350-90: A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease

Active, not recruiting

122

Europe, Canada, Japan, US, RoW

Venglustat (GZ402671), Placebo

Sanofi, Sanofi-Aventis Recherche & Développement

Fabry Disease

12/25

12/26

Agrusa, Antonino

HERNIA, NCT05072171: Evidence of Myogenic Growth Factors in 3D Dynamic Inguinal Hernia Scaffold ProFlor

Active, not recruiting

N/A

Inguinal hernia repair with dynamic prosthesis

University of Palermo

Inguinal Hernia

09/21

12/21

CHECK, NCT03914820: Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. Study.

Recruiting

N/A

330

Europe

HIPEC CO2 surgery, Standard surgery, Mitomycin, HIPEC CO2 surgery with mitomycin

Mario Negri Institute for Pharmacological Research

Colorectal Neoplasms

06/25

RACOMERC, NCT04834011: Radiologic Assessment in Complete Mesocolic Excision for Right Colon Cancer

Recruiting

N/A

100

Europe

Laparoscopic right colonic resection with Complete Mesocolic Excision (CME), 3D CT angiography

University of Palermo

Right-sided Colon Cancer

12/20

12/23

CLARAS, NCT05322265: Complication in Laparoscopic Renal and Adrenal Surgery

Recruiting

N/A

350

Europe

laparoscopic surgery for renal and adrenal diseases

University of Palermo, Fundacio Puigvert

Adrenal Disease, Renal Cancer, Surgery--Complications

03/22

05/22

Novo, Giuseppina

RICMAF, NCT06806813: Italian Anderson Fabry Disease Cardiovascular Registry

Recruiting

N/A

800

Europe

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Fabry Disease

01/31

12/31

NCT06275113: BRING-UP Prevention

Recruiting

N/A

6000

Europe

Heart Care Foundation

Ischemic Heart Disease, Cerebrovascular Disorders, Peripheral Arterial Disease

06/26

NCT06086132: Detection and Prevention of Cancer-Related Cardiovascular Toxicity Registry

Not yet recruiting

N/A

10000

Europe, RoW

Prospective validation of the HFA-ICOS risk score in a subset of subjects with newly diagnosed breast cancer and undergoing treatment with anthracyclines analogues with or without radiotherapy, Non-interventional patient registry

University of Bologna, Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo

Cancer Related Cardiovascular Toxicity

12/26

Chiantera, Vito

NCT05812937: Intraoperative Intraabdominal Ultrasound for Endometriosis

Recruiting

N/A

Europe

Intraabdominal ultrasound, Laparoscopic visualization, Laparoscopic palpation, Direct palpation in case of a conventional segmental bowel resection with specimen extraction per minilaparotomy.

University of Palermo

Endometriosis, Endometriosis; Bowel, Ultrasound Therapy; Complications

01/23

12/23

NCT06689956: Outcomes of Low-Risk Endometrial Cancer with Isolated Tumor Cells in the Sentinel Lymph Nodes: a Prospective, Multicenter, Cohort Study

Recruiting

N/A

212

Europe, Canada, US, RoW

Non-Interventional Study

Mayo Clinic

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Stage IA1 Endometrial Cancer FIGO 2023, Stage IA2 Endometrial Cancer FIGO 2023

10/29

Buono, Giuseppe Di

ProPro, NCT06556498: Progrip Versus ProFlor: Two Fixation Free Devices for Laparoscopic Inguinal Hernia Repair

Enrolling by invitation

150

Europe

Proflor group, Progrip group

University of Palermo

Hernia, Inguinal, Laparoscopic Surgery

12/23

12/25

CLARAS, NCT05322265: Complication in Laparoscopic Renal and Adrenal Surgery

Recruiting

N/A

350

Europe

laparoscopic surgery for renal and adrenal diseases

University of Palermo, Fundacio Puigvert

Adrenal Disease, Renal Cancer, Surgery--Complications

03/22

05/22

Giunta, Rocco

CTO-DENOVO, NCT05977842: Drug-coated Balloon in de Novo Chronic Total Occlusions

Recruiting

N/A

250

Europe, RoW

CTO PCI using DCB-only strategy

National Institute of Cardiology, Warsaw, Poland

Coronary Artery Disease, Total Occlusion of Coronary Artery

02/25

03/25

Panzarella, Vera

SYMILIS OCT, NCT06321003: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Recruiting

N/A

200

Europe

OCT (Optical Coherence Tomography)

University of Palermo

Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorder, Oral Leukoplakia, Proliferative Verrucous Leukoplakia, Oral Lichen Planus, Oral Lichenoid Lesion, Graft-versus-host-disease, Oral Erythroplakia, Actinic Keratoses, Actinic Cheilitis, Oral Cancer, Oral Disease

04/27



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