| Ladenson, Paul W |
NCT04892303: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer |
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| Recruiting | 1 | 48 | US | Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI), radiopharmaceutical (RPT) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Recurrent Thyroid Cancer | 12/27 | 12/30 | | |
| Sgouros, George |
NCT04892303: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer |
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| Recruiting | 1 | 48 | US | Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI), radiopharmaceutical (RPT) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Recurrent Thyroid Cancer | 12/27 | 12/30 | | |
| Quon, Harry |
AQUAX2, NCT05926765: A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia |
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| Recruiting | 2 | 120 | Europe, Canada, US | AAV2-hAQP1 Concentration 1, AAV2-hAQP1 Concentration 2, Placebo | MeiraGTx, LLC | Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands | 07/25 | 07/25 | | |
NCT04892303: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer |
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| Recruiting | 1 | 48 | US | Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI), radiopharmaceutical (RPT) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Recurrent Thyroid Cancer | 12/27 | 12/30 | | |
NCT04797390: A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema |
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| Active, not recruiting | N/A | 250 | US | Advanced Pneumatic Compression Device (APCD), Flexitouch, Flexitouch Plus, Usual Care, Complete Decongestive Therapy (CDT), Manual Lymphatic Drainage (MLD) | Tactile Medical, Vanderbilt University Medical Center | Lymphedema, Lymphedema of Face, Lymphedema, Secondary, Lymphedema Due to Radiation, Lymphedema; Surgical | 01/25 | 01/25 | | |
| Recruiting | N/A | 1300 | Europe, US, RoW | | University Hospital Freiburg, Charite University, Berlin, Germany, Johann Wolfgang Goethe University Hospital, University Hospital, Zürich, Wuerzburg University Hospital, University Hospital Schleswig-Holstein, Johannes Gutenberg University Mainz, University Hospital Munich, Friedrich-Alexander-Universität Erlangen-Nürnberg, Case Western Reserve University, Icahn School of Medicine at Mount Sinai, Ohio State University, German Oncology Center, Cyprus, University of Leipzig, Johns Hopkins University, Martin-Luther-Universität Halle-Wittenberg, University of Giessen, Brno University Hospital, Jena University Hospital | HNSCC, Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer, Larynx Cancer | 12/24 | 12/24 | | |
NCT03372148: Role of Pharyngeal High Resolution Manometry and Impedance in Swallow Function of Head and Neck Cancer Patients |
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| Withdrawn | N/A | 40 | US | pHRMi | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Head and Neck Cancer, Dysphagia | 12/27 | 12/30 | | |
| Wang, Hao |
TNK-PLUS, NCT06221371: Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion |
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| Recruiting | 3 | 390 | RoW | rhTNK-tPA, Tenecteplase, direct EVT | Beijing Tiantan Hospital, Linyi People's Hospital | Ischemic Stroke, Acute, Thrombolysis, Endovascular Treatment | 12/24 | 05/25 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer |
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| Active, not recruiting | 3 | 866 | Europe, Japan, US, RoW | Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219 | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasms, Neoplasm Metastasis | 06/24 | 08/27 | | |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
NCT04927481: A Study of Mitoxantrone Hydrochloride Liposome Injection in Patients With Advanced HER2 Negative Breast Cancer |
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| Terminated | 2 | 28 | RoW | Mitoxantrone Hydrochloride Liposome Injection | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Breast Cancer | 01/23 | 01/23 | | |
NCT04892498: Hypofractionated Radiotherapy Combined With PD-1 Inhibitor Sequential GM-CSF and IL-2 for the Treatment of Advanced Refractory Solid Tumors (PRaG2.0) |
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| Recruiting | 2 | 66 | RoW | Hypofractionated radiotherapy, PD-1 inhibitor, GM-CSF, IL-2 | Second Affiliated Hospital of Soochow University | Advanced Refractory Solid Tumors | 08/23 | 08/24 | | |
NCT03478358: Treatment Using 177Lu-DOTA-EB-TATE in Patients With Advanced Neuroendocrine Tumors |
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| Recruiting | 1 | 60 | RoW | 177Lu-DOTA-EB-TATE 1, 177Lu-DOTA-TATE, 177Lu-DOTA-EB-TATE 2, 177Lu-DOTA-EB-TATE 3, 3.7 GBq (100 mCi) of 177Lu-DOTA-EB-TATE with amino acids (lysine and arginine), 3.7 GBq (100 mCi) of 177Lu-DOTA-EB-TATE without amino acids (lysine and arginine) | Peking Union Medical College Hospital | Neuroendocrine Tumors | 12/22 | 05/23 | | |
NCT04748068: Use of Glidesheath Slender to Reduce Radial Artery Occlusion Following 7 French Transradial Coronary Intervention |
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| Not yet recruiting | N/A | 500 | RoW | 7-Fr Glidesheath Slender, Glidesheath Slender, Terumo, Tokyo, Japan, Cordis 7-Fr radial sheath | China National Center for Cardiovascular Diseases | Radial Artery Occlusion, Coronary Artery Disease | 05/21 | 05/21 | | |
| Recruiting | N/A | 3500 | RoW | | Tang-Du Hospital, Esaote (Shenzhen) Medical Equipment Co. Ltd, The First Affiliated Hospital, Zhejiang University School of Medicine, Shannxi Provincial People's Hospital, Shengjing Hospital, First Hospital of China Medical University, Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Renmin Hospital of Wuhan University, Beijing University of Chinese Medicine Third Affiliated Hospital, The First Affiliated Hospital of Shanxi Medical University, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, The First Hospital of Jilin University, The Afffiliated Hospital of Guizhou Medical University, Yan An Hospital Affiliated to Kunming Medical University, Second Affiliated Hospital of Guangzhou Medical University, Third Xiangya Hospital of Central South University, Ruijin Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Anhui Medical University, The Second Hospital of Anhui Medical University, The First Affiliated Hospital of USTC, The Affiliated Hospital of Qingdao University, First Affiliated Hospital of Xinjiang Medical University, Hospital of Northwestern Polytechnical University, GEM Flower Xian Changqing Staff Hospital, Xi'an Central Hospital, The Second Affiliated Hospital of Xi'an Medical University, Second Affiliated Hospital of Xi'an Jiaotong University, First Affiliated Hospital of Guangxi Medical University, Karamay Central Hospital of Xinjiang, The Fourth Affiliated Hospital of Xinjiang Medical University, Xi'an No.1 Hospital, Xianyang Hospital of Yan'an University, General Hospital of Xinjiang Production and Construction Corps, Air Force Medical Center | Healthy, Adults, Carotid Intima-media Thickness, Vascular Stiffness, Chinese | 05/22 | 05/22 | | |
NCT06014476: Psychological Symptoms and Burden in Caregivers of Patients With Disorders of Consciousness |
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| Completed | N/A | 256 | RoW | questionnaires, Coma Recovery Scale-Revised (CRS-R) | Hangzhou Normal University | Psychological Distress, Anxiety Depression, Burden, Caregiver, Disorders of Consciousness | 10/22 | 10/22 | | |
GIANT, NCT04765592: Guo's Aortic Arch Reconstruction :The Prospective ,Multiple Center Study About the Safety and Efficacy of WeFlow-Arch Modeler Embedded Branch Stent Graft System ( Study) |
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| Active, not recruiting | N/A | 88 | RoW | WeFlow-Arch Modeler Embedded Branch Stent Graft System | Hangzhou Endonom Medtech Co., Ltd. | Aortic Arch Aneurysm | 02/25 | 02/29 | | |
NCT06143540: Clinical Study of 18F-FAPI-RGD in Interstitial Lung Disease Associated With Connective Tissue Disease |
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| Recruiting | N/A | 30 | RoW | | Sichuan Provincial People's Hospital | Interstitial Lung Disease | 05/24 | 07/24 | | |
NCT05944198: Clinical Study of 18F-FAPI-RGD PET/CT in Rheumatoid Arthritis |
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| Completed | N/A | 40 | RoW | | Sichuan Provincial People's Hospital | Rheumatoid Arthritis | 02/24 | 02/24 | | |
| Not yet recruiting | N/A | 142 | NA | Deep Hyperthermia | Peking University Third Hospital, Beijing Chao Yang Hospital, Beijing Friendship Hospital | Hyperthermia, Radiotherapy | 12/23 | 12/24 | | |
NCT05976620: Clinical Study of 18F-FAPI-RGD in Breast Tumors |
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| Completed | N/A | 30 | RoW | | Sichuan Provincial People's Hospital | Breast Tumors | 12/23 | 02/24 | | |
| Completed | N/A | 30 | RoW | | Sichuan Provincial People's Hospital | Renal Tumor | 01/24 | 02/24 | | |
COSTAR, NCT06583070: SABR Combined With Targeted Therapy and Anti-PD-1 for Recurrent or Metastatic Renal Cancer |
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| Recruiting | N/A | 300 | RoW | Radiation therapy | Peking University First Hospital, Peking University Third Hospital | Radiation Therapy, Metastatic Renal Cancer, Recurrent Renal Cell Cancer | 03/27 | 03/27 | | |
MATESHIP, NCT05290454: mNGS -Guided Antimicrobial Treatment in Early Severe Community-Acquired Pneumonia Among Immunocompromised Patients |
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| Recruiting | N/A | 342 | RoW | mNGS-guided treatment | Qilu Hospital of Shandong University, Jinan Central Hospital | Severe Acute Respiratory Infection, Community-acquired Pneumonia, Respiratory Tract Infections, Pneumonia, Infections | 06/24 | 09/24 | | |
| Recruiting | N/A | 100 | RoW | | Sichuan Provincial People's Hospital | Neoplasms | 09/24 | 10/24 | | |
| Recruiting | N/A | 30 | RoW | | Sichuan Provincial People's Hospital | Urothelial Carcinoma | 09/24 | 10/24 | | |
| Not yet recruiting | N/A | 550 | RoW | lymph node dissection, Fluorescence-guided laparoscopic surgery, Radical operation for rectal cancer and sigmoid Cancer | Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Fudan University, Fujian Province Tumor Hospital, Guangdong Provincial People's Hospital, Shengjing Hospital, Affiliated Hospital of Qinghai University, Hebei Medical University Fourth Hospital, The Second Affiliated Hospital of Harbin Medical University, Jiangxi Provincial Cancer Hospital, The First Hospital of Jilin University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Shanxi Province Cancer Hospital, Nanfang Hospital, Southern Medical University, Second People's Hospital of Yunnan Province, Binzhou Medical University, The First Affiliated Hospital of University of Science and Technology of China, First Affiliated Hospital of Chengdu Medical College, The Second People's Hospital of Yibin, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Colorectal Neoplasms, Fluorescence, Lymph Node Excision | 12/26 | 06/27 | | |
ENDURE-APAC, NCT05578300: Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific |
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| Recruiting | N/A | 350 | RoW | Thrombus analyses, Imaging assessment | Chinese University of Hong Kong, Linyi People's Hospital | Ischemic Stroke, Stroke, Stroke, Acute, Stroke, Ischemic, Brain Diseases, Major Adverse Cardiovascular Event | 10/32 | 12/32 | | |
| Recruiting | N/A | 100000 | RoW | Multi-disciplinary assessment | Beijing Tiantan Hospital | Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure, Aortic Diseases, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Cerebral Infarction, Occlusion and Stenosis of Precerebral Arteries, Occlusion and Stenosis of Cerebellar Arteries, Cerebral Aneurysm, Moyamoya Disease, Arteriovenous Malformation of Cerebral Vessels | 12/32 | 12/32 | | |
NCT05348902: Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report |
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| Recruiting | N/A | 1 | RoW | In this study, only cases were collected and reported without any intervention or adverse reactions | Second Affiliated Hospital, School of Medicine, Zhejiang University | Locked-In Syndrome；Pulmonary Arteriovenous Malformation | 06/22 | 06/22 | | |
| Pai, Sara |
NCT02632344: Pembrolizumab for HPV-associated Recurrent Respiratory Papilloma Patients |
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| Active, not recruiting | 2 | 21 | US | Pembrolizumab, Keytruda, MK-3475 | Massachusetts General Hospital, Merck Sharp & Dohme LLC | Recurrent Respiratory Papillomatosis | 02/22 | 07/24 | | |
NCT04645602: Lenvatinib and Pembrolizumab Combination Therapy In HPV-associated Recurrent Respiratory Papillomatosis Patients With Laryngeal, Tracheal, and/or Pulmonary Involvement |
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| Not yet recruiting | 2 | 20 | US | Lenvatinib, Lenvima, Pembrolizumab, Keytruda | Yale University, Eisai Inc., Merck Sharp & Dohme LLC | Human Papilloma Virus, Recurrent Respiratory Papillomatosis | 12/26 | 12/27 | | |
NCT03019003: Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer Patients |
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| Active, not recruiting | 1/2 | 13 | US | Oral Decitabine, ASTX 727, Durvalumab, MEDI4736 | Massachusetts General Hospital, AstraZeneca, Astex Pharmaceuticals, Inc. | Head and Neck Cancer | 01/25 | 01/25 | | |
NCT06412172: The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP) |
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| Recruiting | N/A | 100 | US | | Massachusetts General Hospital | Recurrent Respiratory Papillomatosis, Pulmonary Neoplasm | 04/26 | 04/30 | | |
| Sharabi, Andrew |
NCT02843165: Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation in Advanced Metastatic Disease |
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| Active, not recruiting | 2 | 146 | US | Checkpoint blockade immunotherapy, Checkpoint blockade immunotherapy plus SBRT | University of California, San Diego | Metastatic Cancer | 08/21 | 06/23 | | |
| Recruiting | 2 | 100 | US | Restriction Spectrum Imaging Magnetic Resonance Imaging, RSI-MRI | University of California, San Diego | Prostate Cancer | 12/24 | 12/26 | | |
| Santhanam, Prasanna |
NCT04892303: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer |
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| Recruiting | 1 | 48 | US | Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI), radiopharmaceutical (RPT) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Recurrent Thyroid Cancer | 12/27 | 12/30 | | |
| Recruiting | N/A | 10 | US | Cervical Collar Therapy Indicator (COTI) | Johns Hopkins University | Thyroid Cancer, Graves Disease | 10/26 | 12/26 | | |
| Hobbs, Robert |
NCT04892303: Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer |
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| Recruiting | 1 | 48 | US | Combination treatment (CXRPT) of external beam radiation (XRT) plus radioactive iodine (RAI), radiopharmaceutical (RPT) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI) | Recurrent Thyroid Cancer | 12/27 | 12/30 | | |
NCT04517643: TheraSphere® For Treatment of Metastases in Liver |
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| Completed | N/A | 4 | US | Therasphere Therapy | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Colorectal Cancer Metastatic, Colorectal Cancer | 09/21 | 12/22 | | |
