Princess Margaret Cancer Centre - UHN
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 8 Trials 
15 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Han, Kathy
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
RAINBO, NCT05255653: Refining Adjuvant Treatment in Endometrial Cancer Based on Molecular Features

Recruiting
2/3
1615
Europe, Canada
Olaparib, Lynparza, Pelvic external beam radiotherapy, EBRT, Chemotherapy, Cisplatin, Carboplatin, Paclitaxel, Durvalumab, Imfinzi, Medroxyprogesterone Acetate, Progestogen, Megestrol Acetate, Vaginal brachytherapy, Observation
Leiden University Medical Center, Institute Gustave Roussy (sponsor p53abn-RED trial), Leiden University Medical center (sponsor MMRd-GREEN trial), University College London (sponsor NSMP-ORANGE trial), Canadian Clinical Trials Group (sponsor POLEmut-BLUE trial), Dutch Gynaecological Oncology Group, Comprehensive Cancer Centre The Netherlands, Cancer Research UK & UCL Cancer Trials Centre, Dutch Cancer Society, AstraZeneca, National Cancer Institute, France, Canadian Institutes of Health Research (CIHR)
Endometrial Cancer
01/30
01/31
SPARTACUSII, NCT04890912: Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II

Recruiting
2
50
Canada
Conventional Fractionation, Hypofractionation
Sunnybrook Health Sciences Centre, Princess Margaret Hospital, Canada, Royal Victoria Hospital, Canada, Credit Valley Hospital, London Regional Cancer Program, Canada
Endometrial Cancer
06/22
06/23
CCTG EN10, NCT05640999: Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Recruiting
2
393
Europe, Canada, US, RoW
Vaginal brachytherapy, Adjuvant radiotherapy (EBRT +/- brachytherapy), Observation
Canadian Cancer Trials Group, Canadian Cancer Clinical Trials Network
Endometrial Cancer
12/28
06/29
HPVDNA02, NCT03853915: FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II)

Recruiting
N/A
64
Canada
[18-F]- FDG - PET
University Health Network, Toronto, Sunnybrook Health Sciences Centre
Cervical Cancer
12/26
12/26
LANDMARC, NCT04665388: LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers

Recruiting
N/A
105
Canada
University Health Network, Toronto
Solid Tumor
02/26
02/26
Whelan, Tim
NCT05654922: Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

Recruiting
3
100
US
ARINA-1, Standard of care only
Renovion, Inc.
Pre-Bronchiolitis Obliterans Syndrome
05/26
11/26
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
LUMINA, NCT01791829: A Prospective Cohort Study Evaluating Risk of Local Recurrence Following Breast Conserving Surgery and Endocrine Therapy in Low Risk Luminal A Breast Cancer

Active, not recruiting
N/A
500
Canada
Ontario Clinical Oncology Group (OCOG), British Columbia Cancer Agency
Breast Cancer
03/23
07/27
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35
DeMedeiros, Brenda
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35
Gillman, Vicky
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
Rio, Lily Hallett
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Han, Kathy
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
RAINBO, NCT05255653: Refining Adjuvant Treatment in Endometrial Cancer Based on Molecular Features

Recruiting
2/3
1615
Europe, Canada
Olaparib, Lynparza, Pelvic external beam radiotherapy, EBRT, Chemotherapy, Cisplatin, Carboplatin, Paclitaxel, Durvalumab, Imfinzi, Medroxyprogesterone Acetate, Progestogen, Megestrol Acetate, Vaginal brachytherapy, Observation
Leiden University Medical Center, Institute Gustave Roussy (sponsor p53abn-RED trial), Leiden University Medical center (sponsor MMRd-GREEN trial), University College London (sponsor NSMP-ORANGE trial), Canadian Clinical Trials Group (sponsor POLEmut-BLUE trial), Dutch Gynaecological Oncology Group, Comprehensive Cancer Centre The Netherlands, Cancer Research UK & UCL Cancer Trials Centre, Dutch Cancer Society, AstraZeneca, National Cancer Institute, France, Canadian Institutes of Health Research (CIHR)
Endometrial Cancer
01/30
01/31
SPARTACUSII, NCT04890912: Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II

Recruiting
2
50
Canada
Conventional Fractionation, Hypofractionation
Sunnybrook Health Sciences Centre, Princess Margaret Hospital, Canada, Royal Victoria Hospital, Canada, Credit Valley Hospital, London Regional Cancer Program, Canada
Endometrial Cancer
06/22
06/23
CCTG EN10, NCT05640999: Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Recruiting
2
393
Europe, Canada, US, RoW
Vaginal brachytherapy, Adjuvant radiotherapy (EBRT +/- brachytherapy), Observation
Canadian Cancer Trials Group, Canadian Cancer Clinical Trials Network
Endometrial Cancer
12/28
06/29
HPVDNA02, NCT03853915: FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II)

Recruiting
N/A
64
Canada
[18-F]- FDG - PET
University Health Network, Toronto, Sunnybrook Health Sciences Centre
Cervical Cancer
12/26
12/26
LANDMARC, NCT04665388: LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers

Recruiting
N/A
105
Canada
University Health Network, Toronto
Solid Tumor
02/26
02/26
Whelan, Tim
NCT05654922: Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

Recruiting
3
100
US
ARINA-1, Standard of care only
Renovion, Inc.
Pre-Bronchiolitis Obliterans Syndrome
05/26
11/26
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
LUMINA, NCT01791829: A Prospective Cohort Study Evaluating Risk of Local Recurrence Following Breast Conserving Surgery and Endocrine Therapy in Low Risk Luminal A Breast Cancer

Active, not recruiting
N/A
500
Canada
Ontario Clinical Oncology Group (OCOG), British Columbia Cancer Agency
Breast Cancer
03/23
07/27
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35
DeMedeiros, Brenda
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35
Gillman, Vicky
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
Rio, Lily Hallett
RHEAL, NCT04228991: Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Recruiting
3
588
Canada
Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
Ontario Clinical Oncology Group (OCOG)
Breast Neoplasms, Radiotherapy, Lymphedema
09/25
12/30
ELISA, NCT04797299: Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ (DCIS)

Recruiting
N/A
526
Canada
Ontario Clinical Oncology Group (OCOG)
DCIS
03/35
05/35

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