NCT04049786: Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol |
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| Enrolling by invitation | 4 | 120 | US | Digestive biopsy, Carvedilol 25mg, Serial blood sampling for PK analysis, Metoprolol 100 mg for CYP2D6 phenotyping, Simvastatin 40mg, SVA, Midazolam 2 mg for CYP3A4 phenotyping, MDZ, Genotyping | Natalia Valadares de Moraes, Fundação de Amparo à Pesquisa do Estado de São Paulo, University of Sao Paulo | Obesity, Bariatric Surgery, Roux-en Y Gastric Bypass | 08/22 | 08/23 | | |