The Royal Children's Hospital
Welcome,         Profile    Billing    Logout  
 11 Trials 
37 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Ryan, Monique
NCT02948244: Effect of Creatine Monohydrate on Functional Muscle Strength in Children With FSHD

Completed
N/A
11
RoW
Creatine Monohydrate, Placebo
Murdoch Childrens Research Institute
Facio-Scapulo-Humeral Dystrophy, FSHD2, FSHD1
01/21
07/22
Formosa, Melissa
SBoCK, NCT02193841: Simple Bone Cysts in Kids

Recruiting
3
160
Europe, Canada, US, RoW
Curettage with puncture (C & P), Curette, Vitoss morsels, Tri-calcium phosphate bone graft substitute
The Hospital for Sick Children, Canadian Institutes of Health Research (CIHR)
Bone Cyst
03/27
03/27
Curtis, Nigel
COSI BAIR, NCT05168709: Investigating COVID-19 Vaccine Immunity in Children in the Melbourne Infant Study of BCG for Allergy and Infection Reduction

Completed
4
51
RoW
Tozinameran, COMIRNATY, BNT162b2 [mRNA], Pfizer COVID-19 Vaccine
Murdoch Childrens Research Institute
COVID-19, Vaccine Reaction, Immunization; Infection
09/22
09/22
MIS BAIR, NCT01906853: Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction

Active, not recruiting
3
1272
RoW
BCG, BCG vaccine - Denmark strain, BCG Denmark, Statens Serum Institute BCG vaccine, Mycobacterium bovis BCG (Bacille Calmette Guérin), Danish Strain 1331
Murdoch Childrens Research Institute, Royal Children's Hospital, Mercy Hospital for Women, Australia, University of Melbourne
Allergy, Eczema, Respiratory Tract Infections
09/23
12/24
Rico, Salvador
ETX-DS-005, NCT06283212: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome

Recruiting
1/2
4
Europe
ETX101
Encoded Therapeutics
Dravet Syndrome
12/29
12/29
ENDEAVOR, NCT05419492: A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children with SCN1A-Positive Dravet Syndrome

Recruiting
1/2
22
US
ETX101
Encoded Therapeutics
Dravet Syndrome
04/27
04/31
NCT06112275: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Recruiting
1/2
4
RoW
ETX101
Encoded Therapeutics
Dravet Syndrome
12/29
12/29
ENVISION, NCT04537832: Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Terminated
N/A
58
Europe, US, RoW
No Intervention
Encoded Therapeutics
Dravet Syndrome
03/23
03/23
Woodcock, Ian R
ENVISION, NCT05881408 / 2020-002372-13: A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)

Recruiting
3
148
Europe, Japan, US, RoW
delandistrogene moxeparvovec, SRP-9001, delandistrogene moxeparvovec-rokl, ELEVIDYS, placebo
Sarepta Therapeutics, Inc., Hoffmann-La Roche
Duchenne Muscular Dystrophy
05/27
06/28
NCT05938023: A Study of ATL1102 or Placebo in Participants with Non-ambulatory Duchenne Muscular Dystrophy

Terminated
2
48
Europe, RoW
ATL1102 25mg, ATL1102 50mg, Placebo
Percheron Therapeutics
Duchenne Muscular Dystrophy
11/24
01/25
DELIVER, NCT05524883 / 2021-005478-24: Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping

Recruiting
1/2
88
Europe, Canada, US, RoW
DYNE-251, Placebo
Dyne Therapeutics, Dyne Therapeutics, Inc
Duchenne Muscular Dystrophy (DMD)
11/29
11/29
NCT02948244: Effect of Creatine Monohydrate on Functional Muscle Strength in Children With FSHD

Completed
N/A
11
RoW
Creatine Monohydrate, Placebo
Murdoch Childrens Research Institute
Facio-Scapulo-Humeral Dystrophy, FSHD2, FSHD1
01/21
07/22
Gwee, Amanda
SNAP, NCT05137119: Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting
4
8000
Europe, Canada, RoW
Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging
University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute
Staphylococcus Aureus Bacteremia
12/28
12/28
BEST, NCT04538053: BonE and Joint Infections - Simplifying Treatment in Children Trial

Recruiting
4
285
RoW
Oral cefalexin only, IV cefazolin or IV flucloxacillin followed by oral cefalexin
Murdoch Childrens Research Institute
Bone Infection, Septic Arthritis, Bone and Joint Infection, Osteomyelitis
12/26
12/26
FosUTI, NCT05709028: Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections

Recruiting
3
300
RoW
Fosfomycin, Standard of care antibiotics
University of Sydney
Urinary Tract Infections
08/27
08/27
ITCHY, NCT05500326: Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age ( Study)

Not yet recruiting
2
120
RoW
Ivermectin Tablets
Murdoch Childrens Research Institute, Burnet Institute, Lao Tropical and Public Health Institute
Scabies; Itch, Scabies
06/26
06/26
ID-MAGIC, NCT06574789: Individualised Dose Optimisation of Ganciclovir in Immunocompromised Children Trial

Recruiting
2
232
RoW
Standard dosing of IV ganciclovir, Personalised dosing of IV ganciclovir
Murdoch Childrens Research Institute
Cytomegalovirus Viraemia
06/28
12/28
Mokhtarani, Masoud
NCT05709314: A Study of AMDX-2011P in Participants With CAA

Recruiting
2
25
US
AMDX-2011P
Amydis Inc., National Institutes of Health (NIH), National Institute on Aging (NIA)
Cerebral Amyloid Angiopathy
11/24
12/24
PROBE, NCT05542576: AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy

Recruiting
1/2
36
US
AMDX2011P
Amydis Inc.
Parkinson Disease, Amyotrophic Lateral Sclerosis
09/23
12/23
Dabscheck, Gabriel
NCT05196854: Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

Completed
N/A
54
RoW
Group 1. Standard Home Blood Pressure Measurement, Group 2. Hypnosis script prior to home blood pressure measurement
Murdoch Childrens Research Institute
Hypertension, Neurofibromatosis 1, Blood Pressure
03/23
04/23
Sullivan, Michael
NCT03533582: Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Active, not recruiting
3
537
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP 16213, VP-16, VP-16-213, VP-16213, VP16, VP16213, Fluorouracil, 5 Fluorouracil, 5 Fluorouracilum, 5 FU, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-Fu, 5FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Irinotecan, Oxaliplatin, 1-OHP, Ai Heng, Aiheng, Dacotin, Dacplat, Diaminocyclohexane Oxalatoplatinum, Eloxatin, Eloxatine, Elplat, JM 83, JM-83, JM83, Oxalatoplatin, Oxalatoplatinum, RP 54780, RP-54780, RP54780, SR 96669, SR-96669, SR96669, Patient Observation, Active Surveillance, deferred therapy, expectant management, Observation, Watchful Waiting, Resection, Surgical Resection, Sorafenib, BA4 43 9006, BAY 43 9006, BAY 43-9006, BAY 439006, BAY-43-9006, Bay-439006, BAY439006, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate
Children's Oncology Group, National Cancer Institute (NCI)
Childhood Hepatocellular Carcinoma, Childhood Malignant Liver Neoplasm, Fibrolamellar Carcinoma, Hepatoblastoma, Hepatocellular Malignant Neoplasm, Not Otherwise Specified
12/26
12/26
IGNX-T1, NCT06331728: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001

Recruiting
1
24
RoW
IGNX001, Placebo
IgGenix Australia Pty Ltd
Peanut Allergy
10/25
10/25
NCT06729580: Risk-Targeted Behavioural Activation for the Management of Treatment-Resistant Depression.

Completed
N/A
118
Canada
Behavioural Activation
McGill University
Treatment Resistant Depression (TRD)
10/23
10/23
Loh, Brian
SBoCK, NCT02193841: Simple Bone Cysts in Kids

Recruiting
3
160
Europe, Canada, US, RoW
Curettage with puncture (C & P), Curette, Vitoss morsels, Tri-calcium phosphate bone graft substitute
The Hospital for Sick Children, Canadian Institutes of Health Research (CIHR)
Bone Cyst
03/27
03/27
Boast, Alison
BEST, NCT04538053: BonE and Joint Infections - Simplifying Treatment in Children Trial

Recruiting
4
285
RoW
Oral cefalexin only, IV cefazolin or IV flucloxacillin followed by oral cefalexin
Murdoch Childrens Research Institute
Bone Infection, Septic Arthritis, Bone and Joint Infection, Osteomyelitis
12/26
12/26
Scheffer, Ingrid
NCT05219617 / 2022-001256-42: Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

Recruiting
3
252
Europe, US, RoW
Carisbamate
SK Life Science, Inc., SK Life Science, Inc
Seizures, Lennox Gastaut Syndrome
06/25
06/26
SKYWAY, NCT04938427 / 2021-002481-40: A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

Completed
3
270
Europe, Canada, Japan, US, RoW
Placebo, Soticlestat, TAK-935
Takeda
Lennox Gastaut Syndrome (LGS)
01/24
01/24
SKYLINE, NCT04940624 / 2021-002480-22: A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Completed
3
144
Europe, Canada, Japan, US, RoW
Soticlestat, TAK-935, Placebo
Takeda
Dravet Syndrome (DS)
04/24
04/24
NCT05067634 / 2020-005344-27: Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age with Partial-onset (focal) Seizures

Recruiting
3
140
Europe, US, RoW
Xcopri
SK Life Science, Inc.
Partial Epilepsy
05/26
07/26
ENDYMION 2, NCT05163314 / 2021-002482-17: A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

Recruiting
3
400
Europe, Canada, Japan, US, RoW
Soticlestat, TAK-935
Takeda
Dravet Syndrome (DS), Lennox Gastaut Syndrome (LGS)
05/26
05/26
ACTRN12618001706268: EP1 cannabidiol enriched cannabis oil in refractory epilepsy

Not yet recruiting
2
40
 
Cann Pharmaceutical Australia Limited, Cann Pharmaceutical Australia Limited
Paediatric medication-resistant epilepsy
 
 
ACTRN12618000516280: Clinical study of Cannabidiol in children and adolescents with Developmental and Epileptic Encephalopathy

Recruiting
2
55
 
Zynerba Pharmaceuticals Pty Ltd, Zynerba Pharmaceuticals Pty Ltd
Epilepsy, Developmental disability
 
 
NCT06112275: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Recruiting
1/2
4
RoW
ETX101
Encoded Therapeutics
Dravet Syndrome
12/29
12/29
Cooper, Celia M
BEST, NCT04538053: BonE and Joint Infections - Simplifying Treatment in Children Trial

Recruiting
4
285
RoW
Oral cefalexin only, IV cefazolin or IV flucloxacillin followed by oral cefalexin
Murdoch Childrens Research Institute
Bone Infection, Septic Arthritis, Bone and Joint Infection, Osteomyelitis
12/26
12/26
Koh, Sue May
POPCORN, NCT06186141: Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

Recruiting
4
690
RoW
Morphine, Oxycodone, Oxycodone Juno, Oxycodone HCI Medsurge
Murdoch Childrens Research Institute
Patient-Controlled Analgesia
03/26
03/27
Adams, Justine
POPCORN, NCT06186141: Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone

Recruiting
4
690
RoW
Morphine, Oxycodone, Oxycodone Juno, Oxycodone HCI Medsurge
Murdoch Childrens Research Institute
Patient-Controlled Analgesia
03/26
03/27
Voss, Lesley
ID-MAGIC, NCT06574789: Individualised Dose Optimisation of Ganciclovir in Immunocompromised Children Trial

Recruiting
2
232
RoW
Standard dosing of IV ganciclovir, Personalised dosing of IV ganciclovir
Murdoch Childrens Research Institute
Cytomegalovirus Viraemia
06/28
12/28

Download Options