| Trusheim, John |
METIS, NCT02831959: Pivotal, Open-label, Randomized Study of Radiosurgery with or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC). |
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| Completed | 3 | 298 | Europe, Canada, US, RoW | NovoTTF-200M device, Best Standard of Care | NovoCure GmbH | Brain Metastases from Non-small Cell Lung Cancer (NSCLC) | 11/24 | 11/24 | | |
DCVax-L EAP, NCT02146066: Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221 |
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| Available | N/A | | US | DCVax-L | Northwest Biotherapeutics | GBM, Glioblastoma Multiforme | | | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Lee, Stuart |
| Recruiting | 4 | 61 | US | Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide) | GT Medical Technologies, Inc. | Glioblastoma | 07/27 | 12/27 | | |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
| Terminated | 2 | 92 | Europe, Japan, US, RoW | BIIB093, Glibenclamide, CIRARA, RP 1127, Placebo | Remedy Pharmaceuticals, Inc. | Brain Contusion | 06/23 | 06/23 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Chen, Clark |
| Recruiting | 4 | 61 | US | Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide) | GT Medical Technologies, Inc. | Glioblastoma | 07/27 | 12/27 | | |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
NCT04690348: Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study |
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| Recruiting | 2 | 99 | US | Craniotomy, Cesium-131 brachytherapy | Memorial Sloan Kettering Cancer Center, GT Medical Technologies, Inc. | Recurrent Brain Metastases | 12/25 | 12/25 | | |
NCT04617002: Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas |
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| Available | N/A | | US | ONC201 (dordaviprone) | Chimerix | Glioma, H3 K27M | | | | |
| Completed | N/A | 1057 | Canada, US | NeuroBlate System | Monteris Medical | Metastatic Brain Tumor, Primary Brain Tumor, Epileptic/Seizure Foci, Movement Disorders | 09/23 | 09/23 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Robin, Adam |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
NCT04690348: Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study |
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| Recruiting | 2 | 99 | US | Craniotomy, Cesium-131 brachytherapy | Memorial Sloan Kettering Cancer Center, GT Medical Technologies, Inc. | Recurrent Brain Metastases | 12/25 | 12/25 | | |
NCT05023772: Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases |
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| Recruiting | N/A | 60 | US | Stereotactic Laser Ablation, Thermal laser ablation therapy, Visualase laser ablation therapy, Stereotactic Radiosurgery, CT guided stereotactic radiosurgery, Stereotactic external beam radiation therapy, MRI guided laser ablation, Intraoperative MRI | Henry Ford Health System, Medtronic | Neoplasm Metastasis, Spinal Cord Diseases, Spinal Cord Compression, Spinal Cord Tumor, Spine Metastases | 09/24 | 09/25 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
