| Poli, Sven |
| Active, not recruiting | 4 | 948 | Europe, Canada, US, RoW | Edoxaban, Lixiana, Savaysa, Non-anticoagulant medical therapy | Population Health Research Institute | Intracranial Hemorrhages, Atrial Fibrillation | 04/26 | 10/26 | | |
| Completed | 3 | 850 | Europe, Canada, US, RoW | Placebo, Nerinetide, NA-1 | NoNO Inc., University of Calgary | Stroke, Acute | 08/23 | 08/23 | | |
TECNO, NCT05499832: Safety and Efficacy of Intra-arterial Tenecteplase for Noncomplete Reperfusion of Intracranial Occlusions |
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| Recruiting | 3 | 156 | Europe | Tenecteplase | Insel Gruppe AG, University Hospital Bern | Ischemic Stroke | 07/25 | 10/25 | | |
REVISION, NCT04965038: Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion |
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| Recruiting | 3 | 422 | Europe | Alteplase | University Hospital Tuebingen | Central Retinal Artery Occlusion | 12/26 | 12/26 | | |
| Recruiting | 3 | 860 | Europe, Canada, Japan, US | Recombinant Activated Factor VII (rFVIIa), NovoSeven, NiaStase, Placebo | Joseph Broderick, MD, Novo Nordisk A/S, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage | 01/28 | 01/28 | | |
| Recruiting | N/A | 160 | Europe | anti-Xa activity point-of-care testing (aXa-POCT), Cascade Abrazo with ENOX and ENOX LR test cards, ecarin clotting time point-of-care testing (ECT-POCT), Cascade Abrazo with DTM test cards | University Hospital Tuebingen, Heart and Diabetes Center North Rhine-Westphalia | Anticoagulation With NOAC | 03/21 | 07/21 | | |
| Recruiting | N/A | 1500 | Europe | | University Hospital Tuebingen | Stroke, Acute, Brain Edema | 12/21 | 03/23 | | |
| Recruiting | N/A | 80 | Europe | | University Hospital Tuebingen, Heart and Diabetes Center North Rhine-Westphalia | Anticoagulation With Direct Oral Anticoagulants | 09/22 | 08/23 | | |
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial |
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| Completed | N/A | 2013 | Europe, Japan, RoW | Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®) | Insel Gruppe AG, University Hospital Bern | Ischaemic Stroke | 12/22 | 05/23 | | |
DO-IT Cohort, NCT06556446: Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants |
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| Recruiting | N/A | 2800 | Europe, Canada, RoW | Tenecteplase and Alteplase | Insel Gruppe AG, University Hospital Bern, Swiss Stroke Trialist Association, Swiss Stroke Registry | Ischemic Stroke | 03/26 | 12/26 | | |
| Active, not recruiting | N/A | 141 | Europe | | University Hospital, Essen | Intracranial Hemorrhages | 04/24 | 03/25 | | |
| Active, not recruiting | N/A | 530 | Europe, Canada, US | endovascular thrombectomy (EVT), solitaire X, Standarad medical care | Dr. Michael D Hill, University of Calgary | Acute Ischemic Stroke | 12/25 | 06/26 | | |
Find-AF2, NCT04371055: Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study |
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| Recruiting | N/A | 5200 | Europe | 7-day Holter ECG, Implantable cardiac monitor, Standard of care | University of Leipzig, Johannes Gutenberg University Mainz | Ischemic Stroke, Atrial Fibrillation | 06/26 | 12/26 | | |
| Kermer, Pawel |
DO-IT Cohort, NCT06556446: Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants |
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| Recruiting | N/A | 2800 | Europe, Canada, RoW | Tenecteplase and Alteplase | Insel Gruppe AG, University Hospital Bern, Swiss Stroke Trialist Association, Swiss Stroke Registry | Ischemic Stroke | 03/26 | 12/26 | | |
Find-AF2, NCT04371055: Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study |
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| Recruiting | N/A | 5200 | Europe | 7-day Holter ECG, Implantable cardiac monitor, Standard of care | University of Leipzig, Johannes Gutenberg University Mainz | Ischemic Stroke, Atrial Fibrillation | 06/26 | 12/26 | | |
| Zeller, Julia |
REVISION, NCT04965038: Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion |
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| Recruiting | 3 | 422 | Europe | Alteplase | University Hospital Tuebingen | Central Retinal Artery Occlusion | 12/26 | 12/26 | | |
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial |
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| Completed | N/A | 2013 | Europe, Japan, RoW | Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®) | Insel Gruppe AG, University Hospital Bern | Ischaemic Stroke | 12/22 | 05/23 | | |
DO-IT Cohort, NCT06556446: Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants |
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| Recruiting | N/A | 2800 | Europe, Canada, RoW | Tenecteplase and Alteplase | Insel Gruppe AG, University Hospital Bern, Swiss Stroke Trialist Association, Swiss Stroke Registry | Ischemic Stroke | 03/26 | 12/26 | | |
| Active, not recruiting | N/A | 530 | Europe, Canada, US | endovascular thrombectomy (EVT), solitaire X, Standarad medical care | Dr. Michael D Hill, University of Calgary | Acute Ischemic Stroke | 12/25 | 06/26 | | |
