| Gomberg, Mardi |
NCT05374447: Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy |
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| Recruiting | N/A | 55 | US | Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy, EBUS-IFB | George Washington University | Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary, Mediastinal Diseases | 10/24 | 03/25 | | |
| Chawla, Lakhmir S |
| Recruiting | N/A | 15 | US | Seraph-100 + State of the Art Care, State of the Art Care | ExThera Medical Corporation, Uniformed Services University of the Health Sciences | Septic Shock | 09/25 | 09/25 | | |
| Completed | N/A | 5 | US | ONCObind (Onco-Seraph) 100 Filter | ExThera Medical Corporation | Pancreatic Ductal Adenocarcinoma (PDAC) | 09/24 | 10/24 | | |
| May, Larissa S |
SEPSIS-SHIELD, NCT04094818: TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis |
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| Completed | N/A | 1441 | Europe, US | TriVerity, InSep, HostDx Sepsis | Inflammatix | Respiratory Tract Infections, Urinary Tract Infections, Intra-Abdominal Infections, Skin and Soft Tissue Infection, Suspected Meningitis/Encephalitis or Any Other Infection, Sepsis | 08/24 | 09/24 | | |
| Bhatia, Perminder |
NCT06453213: Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy |
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| Recruiting | 4 | 90 | US | Cenobamate | SK Life Science, Inc. | Focal Onset Seizure | 05/27 | 07/27 | | |
| Completed | 3 | 507 | Europe, US, RoW | Tavapadon, PF-06649751, CVL-751, Placebo | Cerevel Therapeutics, LLC | Parkinson Disease | 01/24 | 02/24 | | |
| Completed | 3 | 304 | Europe, US, RoW | Tavapadon, PF-06649751, CVL-751, Placebo | Cerevel Therapeutics, LLC | Parkinson Disease | 10/24 | 10/24 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
| Recruiting | 3 | 375 | Europe, US, RoW | Masupirdine 50 mg, SUVN-502, Masupirdine 100 mg, Placebo | Suven Life Sciences Limited, Suven Life Sciences Ltd | Agitation, Alzheimer's Type Dementia | 01/25 | 01/25 | | |
| Terminated | 3 | 1125 | Canada, US, RoW | Simufilam, PTI-125, Placebo | Cassava Sciences, Inc., Premier Research Group plc | Alzheimer Disease | 12/24 | 12/24 | | |
| Active, not recruiting | 3 | 1667 | Japan, US | Remternetug (IV), LY3372993, Remternetug (SC), Placebo | Eli Lilly and Company | Alzheimer's Disease | 06/24 | 03/26 | | |
| Terminated | 3 | 1027 | Europe, Canada, Japan, US, RoW | Aducanumab, BIIB037, Aducanumab-avwa, Aduhelm, Placebo | Biogen, Biogen Idec Research Limited | Alzheimer's Disease | 08/24 | 08/24 | | |
| Active, not recruiting | 3 | 1800 | Europe, Canada, US, RoW | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Obesity, Cardiovascular Diseases | 01/26 | 02/26 | | |
| Active, not recruiting | 3 | 2300 | Europe, Canada, US, RoW | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Obesity, Overweight, Osteoarthritis, Knee, Obstructive Sleep Apnea | 04/26 | 05/26 | | |
NCT06568042: Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy |
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| Recruiting | 2 | 450 | Europe, Canada, Japan, US, RoW | LY3848575, Placebo | Eli Lilly and Company | Neuropathic Pain, Distal Sensory Polyneuropathy | 06/26 | 09/26 | | |
NCT06538116: A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease |
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| Recruiting | 2 | 300 | Japan, US | Mevidalen, LY3154207, Placebo | Eli Lilly and Company | Alzheimer Disease | 12/25 | 01/26 | | |
| Park, James |
NCT06453213: Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy |
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| Recruiting | 4 | 90 | US | Cenobamate | SK Life Science, Inc. | Focal Onset Seizure | 05/27 | 07/27 | | |
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement |
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| Active, not recruiting | N/A | 1948 | Canada, US | ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL | Boston Scientific Corporation | Aortic Stenosis | 06/24 | 09/34 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Kartiko, Susan |
NCT04413799: PVB vs Ketamine/Lidocaine in Rib Fracture Patients |
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| Recruiting | 1 | 170 | US | lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine | George Washington University | Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute | 12/24 | 05/25 | | |
NCT05497115: Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury |
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| Recruiting | N/A | 350 | US | Trauma Resilience and Recovery Program | Medical University of South Carolina, George Washington University, Agency for Healthcare Research and Quality (AHRQ) | Posttraumatic Stress Disorder, Depression | 08/25 | 08/25 | | |
| Diab, Khalil |
ELEVAATE, NCT05856331: Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema |
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| Active, not recruiting | 2 | 99 | Europe, US, RoW | SAR447537, Zemaira, Respreeza | Sanofi | Alpha 1-Antitrypsin Deficiency, Emphysema | 08/25 | 10/25 | | |
NCT04722887: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency |
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| Active, not recruiting | 1/2 | 16 | US | Alpha-1 15%, Liquid Alpha1-Proteinase Inhibitor (Human), Prolastin®-C Liquid | Grifols Therapeutics LLC | Alpha1-Antitrypsin Deficiency | 03/25 | 03/25 | | |
NCT05374447: Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy |
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| Recruiting | N/A | 55 | US | Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy, EBUS-IFB | George Washington University | Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary, Mediastinal Diseases | 10/24 | 03/25 | | |
