UF Health Shands Hospital at the University of Florida
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 15 Trials 
31 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Smith, Barbara L
CLP0008, NCT04440982: Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients

Terminated
2
98
US
LUM015, Lum Imaging System
Lumicell, Inc., National Cancer Institute (NCI)
Breast Cancer, Neoadjuvant Therapy
11/23
02/24
NCT05377424: Adenosine 2A Receptor Antagonism and AIH in ALS

Recruiting
1/2
40
US
Consume 20mg of istradefylline, Nourianz, Low Oxygen therapy, Acute Intermittent Hypoxia, AIH, Placebo counterpart to the istradefylline drug, Placebo, SHAM counterpart to low oxygen therapy., SHAM acute intermittent hypoxia, SHAM-AIH
University of Florida, ALS Association
ALS
12/25
12/25
NCT03303040: Effect of Diaphragm Stimulation During Surgery

Completed
N/A
25
US
Electrical stimulation of hemidiaphragm
University of Florida, National Institutes of Health (NIH), University of Arizona, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Mechanical Ventilation Complication, Diaphragm Injury
05/22
12/23
NCT02354651: Response to Diaphragmatic Pacing in Subjects With Pompe Disease

Completed
N/A
9
US
Diaphragm conditioning via phrenic nerve stimulation
University of Florida, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pompe Disease
06/22
01/23
NCT03645031: Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease

Completed
N/A
29
US
Acute Intermittent Hypoxia, AIH, Sham Acute Intermittent Hypoxia, Sham AIH
University of Florida
Amyotrophic Lateral Sclerosis (ALS), Neuromuscular Diseases
06/23
06/23
NCT05381818: Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

Recruiting
N/A
36
US
Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
University of Florida, National Institute on Aging (NIA)
Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
05/25
08/25
Martin, Daniel
RADIANCE, NCT04230759 / 2018-003005-25: Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. a Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Active, not recruiting
2
180
Europe
Chemotherapy, all brands of 5-fluorouracil (5-FU) are allowed, all brands of Mitomycin C (MMC) are allowed, Radiation, Durvalumab, PD-L1 inhibitor
Goethe University, German Cancer Aid, AstraZeneca
Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II
12/26
03/27
NCT02907398: Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry

Active, not recruiting
N/A
5000
Europe, US
Inspire therapy, ADHERE, No intervention, CONTROL
Inspire Medical Systems, Inc.
Obstructive Sleep Apnea
09/25
12/25
Gabrielli, Andrea
NCT05661695: Evaluation of Clinical Tool to Improve Adherence to Ventilator Management at UM

Not yet recruiting
N/A
50
US
RT Assistant
Convergent Engineering, Inc., University of Miami, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Respiratory Therapy
05/24
05/24
NCT03496181: Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently

Active, not recruiting
N/A
32
Europe, US
Multilingual Aphasia Examination, Language paradigms + RS fMRI, Language paradigms + RS fMRI + one anatomical sequence
Memorial Sloan Kettering Cancer Center
Glioma, Glioma of Brain, Glioma of Spinal Cord
09/25
09/25
Sadasivan, Kalia K
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
Lanz, Jennifer
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
NCT06606119: The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

Recruiting
N/A
275
US
Data and tissue collection
University of Florida, National Institutes of Health (NIH), National Institute of General Medical Sciences (NIGMS)
Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia
10/27
10/28
NCT05357170: Gut Microbiome Dysfunction in Sepsis and Trauma Survivors

Recruiting
N/A
468
US
Human feces collection, Blood sampling
University of Florida, National Institute of General Medical Sciences (NIGMS)
Sepsis, Trauma Injury
05/25
05/26
NCT05110937: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis

Recruiting
N/A
450
US
Blood sampling
University of Florida, National Institute of General Medical Sciences (NIGMS)
Sepsis, Trauma Injury
07/25
04/26
NCT05616130: Pathological Myeloid Activation After Sepsis and Trauma

Recruiting
N/A
255
US
Data Collection, Bone marrow collection and blood collection, Serial interviews to complete surveys and questionnaires, Telephone follow up call, Telephone interview
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury, Sepsis, Immunosuppression, Chronic Critical Illness
09/27
09/28
Efron, Philip
NCT02711709: Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

Active, not recruiting
N/A
53
US
Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics, Mobility Monitors
University of Florida, National Institute on Aging (NIA), National Institutes of Health (NIH)
Sepsis
02/20
12/24
NCT02276417: PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors

Active, not recruiting
N/A
668
US
Blood collection, Urine collection, Bioimpedance Analysis, BIA, Cognitive Function Tests, Quality-of-life Questionnaires, Physical Function Tests, Blood Collection
University of Florida, National Institute of General Medical Sciences (NIGMS), American Heart Association
Sepsis
07/22
07/25
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
NCT05626699: Evaluation of Clinical Tool to Improve Adherence to Ventilator Management

Not yet recruiting
N/A
50
NA
RT Assistant
Convergent Engineering, Inc., University of Florida, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Respiratory Therapy
03/24
03/24
NCT06576570: Evaluation and Modification of Surgeon Ergonomics in the Operation Room Using Artificial Intelligence Analytics

Enrolling by invitation
N/A
30
US
Education presentation of surgical ergonomics, Summary of Ergonomic Measurement System
University of Florida
Work Related Upper Limb Disorder, Musculoskeletal Pain
10/25
12/26
NCT05357170: Gut Microbiome Dysfunction in Sepsis and Trauma Survivors

Recruiting
N/A
468
US
Human feces collection, Blood sampling
University of Florida, National Institute of General Medical Sciences (NIGMS)
Sepsis, Trauma Injury
05/25
05/26
NCT05110937: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis

Recruiting
N/A
450
US
Blood sampling
University of Florida, National Institute of General Medical Sciences (NIGMS)
Sepsis, Trauma Injury
07/25
04/26
NCT05616130: Pathological Myeloid Activation After Sepsis and Trauma

Recruiting
N/A
255
US
Data Collection, Bone marrow collection and blood collection, Serial interviews to complete surveys and questionnaires, Telephone follow up call, Telephone interview
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury, Sepsis, Immunosuppression, Chronic Critical Illness
09/27
09/28
Lyle, Moldawer
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
Leeuwenburgh, Christiaan
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
WISEBrain, NCT02137070: The WISE (Weightloss Intervention Surgical Effects) Brain Study

Completed
N/A
197
US
Bariatric Surgery Candidates, Non surgical/Community volunteers
University of Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes, Weightloss
11/22
11/22
Moore, Frederick
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
Mohr, Alicia
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25
NCT06606119: The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

Recruiting
N/A
275
US
Data and tissue collection
University of Florida, National Institutes of Health (NIH), National Institute of General Medical Sciences (NIGMS)
Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia
10/27
10/28
Parvateneni, Hari
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury

Recruiting
N/A
400
US
Bone marrow collection, Blood collection, Clinical data collection
University of Florida, National Institute of General Medical Sciences (NIGMS)
Trauma Injury
12/24
12/25

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