Smith, Barbara L |
CLP0008, NCT04440982: Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients |
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| Terminated | 2 | 98 | US | LUM015, Lum Imaging System | Lumicell, Inc., National Cancer Institute (NCI) | Breast Cancer, Neoadjuvant Therapy | 11/23 | 02/24 | | |
NCT05377424: Adenosine 2A Receptor Antagonism and AIH in ALS |
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| Recruiting | 1/2 | 40 | US | Consume 20mg of istradefylline, Nourianz, Low Oxygen therapy, Acute Intermittent Hypoxia, AIH, Placebo counterpart to the istradefylline drug, Placebo, SHAM counterpart to low oxygen therapy., SHAM acute intermittent hypoxia, SHAM-AIH | University of Florida, ALS Association | ALS | 12/25 | 12/25 | | |
| Completed | N/A | 25 | US | Electrical stimulation of hemidiaphragm | University of Florida, National Institutes of Health (NIH), University of Arizona, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Mechanical Ventilation Complication, Diaphragm Injury | 05/22 | 12/23 | | |
NCT02354651: Response to Diaphragmatic Pacing in Subjects With Pompe Disease |
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| Completed | N/A | 9 | US | Diaphragm conditioning via phrenic nerve stimulation | University of Florida, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Pompe Disease | 06/22 | 01/23 | | |
NCT03645031: Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease |
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| Completed | N/A | 29 | US | Acute Intermittent Hypoxia, AIH, Sham Acute Intermittent Hypoxia, Sham AIH | University of Florida | Amyotrophic Lateral Sclerosis (ALS), Neuromuscular Diseases | 06/23 | 06/23 | | |
NCT05381818: Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery |
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| Recruiting | N/A | 36 | US | Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC) | University of Florida, National Institute on Aging (NIA) | Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder | 05/25 | 08/25 | | |
Martin, Daniel |
| Active, not recruiting | 2 | 180 | Europe | Chemotherapy, all brands of 5-fluorouracil (5-FU) are allowed, all brands of Mitomycin C (MMC) are allowed, Radiation, Durvalumab, PD-L1 inhibitor | Goethe University, German Cancer Aid, AstraZeneca | Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II | 12/26 | 03/27 | | |
NCT02907398: Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry |
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| Active, not recruiting | N/A | 5000 | Europe, US | Inspire therapy, ADHERE, No intervention, CONTROL | Inspire Medical Systems, Inc. | Obstructive Sleep Apnea | 09/25 | 12/25 | | |
Gabrielli, Andrea |
NCT05661695: Evaluation of Clinical Tool to Improve Adherence to Ventilator Management at UM |
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| Not yet recruiting | N/A | 50 | US | RT Assistant | Convergent Engineering, Inc., University of Miami, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) | Respiratory Therapy | 05/24 | 05/24 | | |
NCT03496181: Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently |
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| Active, not recruiting | N/A | 32 | Europe, US | Multilingual Aphasia Examination, Language paradigms + RS fMRI, Language paradigms + RS fMRI + one anatomical sequence | Memorial Sloan Kettering Cancer Center | Glioma, Glioma of Brain, Glioma of Spinal Cord | 09/25 | 09/25 | | |
Sadasivan, Kalia K |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
Lanz, Jennifer |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
NCT06606119: The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma |
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| Recruiting | N/A | 275 | US | Data and tissue collection | University of Florida, National Institutes of Health (NIH), National Institute of General Medical Sciences (NIGMS) | Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia | 10/27 | 10/28 | | |
NCT05357170: Gut Microbiome Dysfunction in Sepsis and Trauma Survivors |
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| Recruiting | N/A | 468 | US | Human feces collection, Blood sampling | University of Florida, National Institute of General Medical Sciences (NIGMS) | Sepsis, Trauma Injury | 05/25 | 05/26 | | |
NCT05110937: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis |
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| Recruiting | N/A | 450 | US | Blood sampling | University of Florida, National Institute of General Medical Sciences (NIGMS) | Sepsis, Trauma Injury | 07/25 | 04/26 | | |
NCT05616130: Pathological Myeloid Activation After Sepsis and Trauma |
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| Recruiting | N/A | 255 | US | Data Collection, Bone marrow collection and blood collection, Serial interviews to complete surveys and questionnaires, Telephone follow up call, Telephone interview | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury, Sepsis, Immunosuppression, Chronic Critical Illness | 09/27 | 09/28 | | |
Efron, Philip |
NCT02711709: Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty |
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| Active, not recruiting | N/A | 53 | US | Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics, Mobility Monitors | University of Florida, National Institute on Aging (NIA), National Institutes of Health (NIH) | Sepsis | 02/20 | 12/24 | | |
NCT02276417: PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors |
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| Active, not recruiting | N/A | 668 | US | Blood collection, Urine collection, Bioimpedance Analysis, BIA, Cognitive Function Tests, Quality-of-life Questionnaires, Physical Function Tests, Blood Collection | University of Florida, National Institute of General Medical Sciences (NIGMS), American Heart Association | Sepsis | 07/22 | 07/25 | | |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
NCT05626699: Evaluation of Clinical Tool to Improve Adherence to Ventilator Management |
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| Not yet recruiting | N/A | 50 | NA | RT Assistant | Convergent Engineering, Inc., University of Florida, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) | Respiratory Therapy | 03/24 | 03/24 | | |
NCT06576570: Evaluation and Modification of Surgeon Ergonomics in the Operation Room Using Artificial Intelligence Analytics |
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| Enrolling by invitation | N/A | 30 | US | Education presentation of surgical ergonomics, Summary of Ergonomic Measurement System | University of Florida | Work Related Upper Limb Disorder, Musculoskeletal Pain | 10/25 | 12/26 | | |
NCT05357170: Gut Microbiome Dysfunction in Sepsis and Trauma Survivors |
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| Recruiting | N/A | 468 | US | Human feces collection, Blood sampling | University of Florida, National Institute of General Medical Sciences (NIGMS) | Sepsis, Trauma Injury | 05/25 | 05/26 | | |
NCT05110937: Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis |
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| Recruiting | N/A | 450 | US | Blood sampling | University of Florida, National Institute of General Medical Sciences (NIGMS) | Sepsis, Trauma Injury | 07/25 | 04/26 | | |
NCT05616130: Pathological Myeloid Activation After Sepsis and Trauma |
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| Recruiting | N/A | 255 | US | Data Collection, Bone marrow collection and blood collection, Serial interviews to complete surveys and questionnaires, Telephone follow up call, Telephone interview | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury, Sepsis, Immunosuppression, Chronic Critical Illness | 09/27 | 09/28 | | |
Lyle, Moldawer |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
Leeuwenburgh, Christiaan |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
| Completed | N/A | 197 | US | Bariatric Surgery Candidates, Non surgical/Community volunteers | University of Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Diabetes, Weightloss | 11/22 | 11/22 | | |
Moore, Frederick |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
Mohr, Alicia |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |
NCT06606119: The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma |
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| Recruiting | N/A | 275 | US | Data and tissue collection | University of Florida, National Institutes of Health (NIH), National Institute of General Medical Sciences (NIGMS) | Trauma Injury, Trauma, Critical Illness, Microbiome, Chronic Anemia, Acute Blood Loss Anemia | 10/27 | 10/28 | | |
Parvateneni, Hari |
NCT02577731: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury |
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| Recruiting | N/A | 400 | US | Bone marrow collection, Blood collection, Clinical data collection | University of Florida, National Institute of General Medical Sciences (NIGMS) | Trauma Injury | 12/24 | 12/25 | | |