University of Bern
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 51 Trials 
122 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Bosch, Jaime
NCT05470205: Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal

Recruiting
3
660
Europe, US
SHAPE measurement (Sonazoid ultrasoud contrast agent), Sonazoid, SHAPE measurement (Definity ultrasoud contrast agent), Definity
Thomas Jefferson University, University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Bern
Liver Diseases, Portal Hypertension
02/26
04/26
Low, Nicola
NCT06131749: Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

Active, not recruiting
N/A
603
RoW
No intervention
University of Bern, Foundation for Professional Development, Utrecht University, University of Pretoria, University of Cape Town, University of Southern California, University of Alabama at Birmingham, Louisiana State University Health Sciences Center in New Orleans
Sexually Transmitted Infections (Not HIV or Hepatitis), Premature Birth, Pregnancy; Infection, Microbial Colonization, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginitis, Mycoplasma Genitalium Infection, Bacterial Vaginosis, Vaginal Candida, Ureaplasma Urealyticum Infection, Genital Mycoplasma Infection, HIV Infections
04/24
09/24
BEready, NCT06739499: Bern, Get Ready () Cohort Study for Pandemic Preparedness

Recruiting
N/A
2500
Europe
University of Bern, Stiftung Vinetum
Pandemic, COVID-19, Infections, Zoonoses, Epidemic Disease, Respiratory Tract Infections
12/00
12/00
Stettler, Christoph
NCT04049110: Dapagliflozin in Physical Exercise in Type 1 Diabetes

Completed
3
39
Europe
Forxiga 10mg, Dapagliflozin, Placebo
Insel Gruppe AG, University Hospital Bern
Diabetes Mellitus, Type 1
04/23
05/23
NCT04192019: Micro Glucagon During Exercise in Type 1 Diabetes

Withdrawn
1
20
NA
Micro-glucagon, Dasiglucagon, Mini-glucagon
Insel Gruppe AG, University Hospital Bern
Type 1 Diabetes, Hypoglycemia
04/24
06/24
NCT04633590: Home-Based Exercise Gaming for Physically Inactive Individuals

Completed
N/A
27
Europe
Home-based exergaming
University Hospital Inselspital, Berne, University of Bern
Physical Inactivity
01/23
01/23
HypoVoice, NCT05569876: The Study

Completed
N/A
7
Europe
Controlled hypoglycemic state
University Hospital Inselspital, Berne, Idiap Research Institute, CSEM Centre Suisse d'Electronique et de Microtechnique SA, Ludwig-Maximilians - University of Munich
Diabetes Mellitus, Hypoglycemia
01/23
01/23
DE-CAF, NCT04671043: Caffeine Ingestion to Counter the Exercise-mediated Fall in Glycaemia in Type 1 Diabetes

Completed
N/A
21
Europe
Caffeine and glucose, Glucose alone, Placebo
University Hospital Inselspital, Berne
Caffeine and Carbohydrate, Carbohydrate Only, Placebo
02/23
02/23
NCT04487678: Exogenous Ketones in People With Type 1 Diabetes

Withdrawn
N/A
6
NA
Ketone ester supplement, H.V.M.N Ketone Ester food supplement
Insel Gruppe AG, University Hospital Bern
Ketosis, Diabetic
11/23
12/23
GLEAM, NCT06223204: Noninvasive Glucose Measurement Using Impedance Tomography

Completed
N/A
16
Europe
Controlled euglycemia, hypoglycemia and hyperglycemia
Insel Gruppe AG, University Hospital Bern, CSEM Centre Suisse d'Electronique et de Microtechnique SA, Idiap Research Institute
Diabetes Mellitus
04/24
04/24
SwissDiab, NCT01179815: Swiss Diabetes Registry - Study

Recruiting
N/A
1500
Europe
Insel Gruppe AG, University Hospital Bern, Cantonal Hospital of St. Gallen, University of Zurich
Diabetes Mellitus
01/99
01/99
Greif, Robert
NCT04764799: HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management

Completed
N/A
2800
Europe
Rapid sequence induction
Thomas Riva
Respiratory Failure
07/23
12/23
POCA, NCT05316779: Perioperative Cardiac Arrest and Outcome

Completed
N/A
240
Europe
Insel Gruppe AG, University Hospital Bern
Heart Arrest, Anesthesia
09/23
10/23
NCT03759210: Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland

Recruiting
N/A
1000
Europe
Insel Gruppe AG, University Hospital Bern
Resuscitation, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest
12/23
06/24
NCT03749837: C-MAC Video Stylet vs. Video Endoscope

Recruiting
N/A
30
Europe, Canada
C- MAC VS, Video Endoscope
University Hospital Inselspital, Berne
Intubation
12/23
12/23
CRICKET, NCT05804188: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation

Recruiting
N/A
105000
Europe, Canada, US, RoW
tracheal intubation
Thomas Riva, University of Bern, The Hospital for Sick Children, Boston Children’s Hospital, Istituto Giannina Gaslini
Intubation Complication, Adverse Events
12/25
12/25
PAPAYA-III, NCT06117176: Prospective Assessment Project of AirwaY Management-related Incidents in Adult Anaesthesia Care PAPAYA III

Not yet recruiting
N/A
40000
Europe
Insel Gruppe AG, University Hospital Bern, University of Bern, University of Lausanne Hospitals, Kantonsspital Aarau, Charite University, Berlin, Germany, Universitätsklinikum Hamburg-Eppendorf
Airway Complication of Anesthesia, Adverse Events
03/25
03/25
Kuehni, Claudia
HEAR, NCT06036407: Screening for Hearing Loss After Childhood Cancer

Completed
N/A
476
Europe
Hearing test, Hearing evaluation, Hearing assessment, Hearing screening
University of Bern, Krebsforschung Schweiz, Bern, Switzerland
Childhood Cancer, Hearing Loss
07/23
11/24
Cardio-Onco, NCT03790943: Cardiac Dysfunction in Childhood Cancer Survivors

Recruiting
N/A
500
Europe
cardiac assessment
University of Bern, University Hospital, Basel, Switzerland, University Children's Hospital Basel, Insel Gruppe AG, University Hospital Bern, Cantonal Hospital of St. Gallen, Luzerner Kantonsspital, University Hospital, Geneva
Cardiac Dysfunction, Cardiovascular Diseases, Childhood Cancer
12/23
01/24
SPAC, NCT03505216: Swiss Paediatric Airway Cohort

Recruiting
N/A
6000
Europe
University of Bern
Asthma, Wheezing, Cough, Exercise Induced Bronchospasm, Inspiratory Laryngeal Obstruction, Dysfunctional Breathing
06/25
06/30
iPCD, NCT03517865: International Primary Ciliary Dyskinesia Cohort

Recruiting
N/A
5000
Europe
University of Bern, European Commission, Swiss National Science Foundation, University of Southampton, Pierre and Marie Curie University, Bar-Ilan University, Israel, University of Padova, University Hospital, Gasthuisberg, Oslo University Hospital, Amsterdam UMC, location VUmc, Royal Brompton & Harefield NHS Foundation Trust, Marmara University, Ruhr University of Bochum, Genetic Disorders of Mucociliary Clearance Consortium, Institute of Tuberculosis and Lung Disorders, Rabka Poland, University of Sydney, Copenhagen University Hospital, Denmark, University Hospital Muenster, Hannover Medical School, Hospital de Niños R. Gutierrez de Buenos Aires, University of Cyprus, Medical Centre Dr Dragisa Misovic, Hacettepe University, University Hospital, Motol, Clinica de neumologia pediatrica Compensar, Attikon Hospital, University of Leicester
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/50
12/80
NCT04602481: COVID-19 in People With Primary Ciliary Dyskinesia

Recruiting
N/A
1000
Europe
University of Bern, Selbsthilfegruppe Kartagener Syndrom und Primäre Ciliäre Dyskinesie, Verein Kartagener Syndrom und PCD, PCD Support UK, PCD Foundation, PCD Australia, European Lung Foundation, University of Southampton, Universität Luzern, Associazione Italiana Discinesia Ciliare Primaria Sindrome di Kargagener APS, Asociación Nacional de Pacientes con Discinesia Ciliar Primaria, Association Dyskinésie Ciliaire Primitive ADCP
Primary Ciliary Dyskinesia
05/30
05/30
SCCSS, NCT03297034: Swiss Childhood Cancer Survivor Study

Recruiting
N/A
3626
Europe
University of Bern, Swiss Pediatric Oncology Group
Childhood Cancer
01/50
01/50
SPCDR, NCT03606200: Swiss Primary Ciliary Dyskinesia Registry

Recruiting
N/A
800
Europe
University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/80
12/80
Swiss-CP-Reg, NCT04992871: Swiss Cerebral Palsy Registry

Recruiting
N/A
15000
Europe
University of Bern, Schweizerische Stiftung für das cerebral gelähmte Kind
Cerebral Palsy
01/71
01/71
SRDR, NCT05179863: Swiss Rare Disease Registry

Recruiting
N/A
500000
Europe
University of Bern, Federal Office of Public Health, Switzerland, Universitäts-Kinderspital Zürich, University Children's Hospital Basel, Insel Gruppe AG, University Hospital Bern, University Hospital, Zürich, Centre Hospitalier Universitaire Vaudois, University Hospital, Geneva, Proraris Allianz seltener Krankheiten, Kosek National Coordination Rare Diseases Switzerland, Orphanet Suisse, University of Zurich, Kantonsspital Aarau, Ente Ospedaliero Cantonale, Bellinzona, Cantonal Hospital of St. Gallen, Ostschweizer Kinderspital, University Hospital, Basel, Switzerland, Balgrist University Hospital, Centro Malattie Rare della Svizzera Italiana
Rare Diseases
01/71
01/71
Swiss-Reg-NMD, NCT05102916: Swiss Registry for Neuromuscular Disorders

Recruiting
N/A
2000
Europe
University of Bern, University Children's Hospital Basel, Insel Gruppe AG, University Hospital Bern, University of Lausanne Hospitals, Ente Ospedaliero Cantonale, Bellinzona, University Children's Hospital, Zurich
SMA, DMD, BMD, IMD, Congenital Muscular Dystrophy
01/71
01/71
NCT05017142: Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Recruiting
N/A
500
Europe
University of Bern, Schweizerische Multiple Sklerose Gesellschaft, Insel Gruppe AG, University Hospital Bern, Novartis, Anna Mueller Grocholski-Stiftung, Gottfried und Julia Bangerter- Rhyner-Stiftung, Basel, Biogen, Roche Pharma (Switzerland) Ltd, Fondation Johanna Dürmüller-Bol, Kantonsspital Aarau, University Children's Hospital Basel, Ente Ospedaliero Cantonale, Bellinzona, Kantonsspital Graubünden, University Hospital, Geneva, Centre Hospitalier Universitaire Vaudois, Ostschweizer Kinderspital, Kantonsspital Winterthur KSW, Sanofi, Hôpital Fribourgeois, University Children's Hospital, Zurich, Luzerner Kantonsspital
Optic Neuritis, Transverse Myelitis, Acute Disseminated Encephalomyelitis, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, Anti-NMDAR Encephalitis, Anti-GAD65 Associated Autoimmune Encephalitis, Anti-AMPAR-1/2 Associated Autoimmune Encephalitis, Anti-Lgi-1 Associated Autoimmune Encephalitis, Anti-CASPR-2 Associated Autoimmune Encephalitis, Anti-GABAR-1/2 Associated Autoimmune Encephalitis, Onconeuronal Antibody (Hu, Ri, Yo, Amphiphysin, CRMP-5, Ma-1, Ma-2, SOX-1) Associated Autoimmune Encephalitis, Hashimoto Encephalitis, CNS Vasculitis, CNS Sarcoidosis, CNS Lupus, Rasmussen Encephalitis, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
01/71
01/71
SCCSS-FU, NCT04732273: The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)

Recruiting
N/A
3000
Europe
Physical examination, diagnostic tests, laboratory tests, Personal history, questionnaire
University of Bern
Late Effect, Childhood Cancer
01/71
01/71
Herbst, Friedrich
CHINOREC, NCT04124601 / 2019-003865-17: Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer

Completed
2
80
Europe
Chemoradiotherapy, Radiochemotherapy, Chemoradiation, Ipilimumab, Yervoy®, Nivolumab, Opdivo®
Johannes Laengle, MD, PhD, Bristol-Myers Squibb
Rectal Cancer
03/24
03/24
NCT06081868: RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda

Not yet recruiting
N/A
610
Europe
Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene
University of Bern
Dental Caries, Dental Plaque, Dental Diseases, Dental Caries in Children, Oral Disease, Oral Manifestations
09/26
09/26
Bassetti, Claudio
NCT05240560: Proof of Concept Study Evaluating BP1.3656 in Patients With Fatigue Following Ischemic Stroke

Terminated
2
5
Europe
BP1.3656
Bioprojet
Fatigue
02/24
02/24
eSATIS, NCT02554487: Early Sleep Apnea Treatment in Stroke

Active, not recruiting
N/A
201
Europe, RoW
AirCurveTM10 CS PACEWAVE Adaptive-Servo-Ventilator (ResMed Ldt., Australia)
University Hospital Inselspital, Berne, Swiss National Science Foundation, TROPOS Stiftung für Humane Verhaltensforschung
Sleep Apnea, Obstructive, Sleep Apnea, Central, Stroke
03/22
11/22
NCT04650438: Sleep and Creativity

Withdrawn
N/A
80
NA
Transcranial Magnetic Stimulation (TMS) over the left inferior frontal gyrus (IFG), Transcranial Magnetic Stimulation (TMS) over the left inferior parietal lobule (IPL)
Insel Gruppe AG, University Hospital Bern
Creativity Performance in Healthy Subjects
02/22
02/22
SPHYNCS, NCT04330963: International Swiss Primary Hypersomnolence and Narcolepsy Cohort Study

Recruiting
N/A
600
Europe
University Hospital Inselspital, Berne, Klinik Barmelweid, Zentrum für Schlafmedizin Basel, Ospedale Regionale di Lugano, Cantonal Hospital of St. Gallen, Zurzach Care Klinik für Schlafmedizin, University Children's Hospital, Zurich, University Children's Hospital Basel, Centre Lausannios de Sommeil, Private Universität Witten-Herdecke and Orfea Fachklinik für Schlafmedizin, Witten, Germany, Leiden University Medical Center, Leiden, Netherlands, University of Bologna, Bologna, Italy
Narcolepsy, Idiopathic Hypersomnia, Hypersomnolence Disorder
12/24
06/26
Amati, Francesca
AGIR, NCT01224886: Age and Insulin Resistance

Recruiting
N/A
150
Europe
Physical activity
University of Lausanne, Centre Hospitalier Universitaire Vaudois
Obesity, Physical Inactivity, Aging
12/28
12/28
Campus, Guglielmo
CaPreXCh, NCT04420780: Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh

Not yet recruiting
N/A
409
RoW
Administration of sugar-free gums sugar-free gums containing 100% Xylitol as sweetener, Administration of sugar-free gums sugar-free gums containing containing a polyols mixture plus a low amount of Xylitol (22%)
University of Bern, University of Milan, University of Sassari, Italy, WHO Collaborating Center for Epidemiology and Preventive Dentistry
Caries
07/23
08/24
NCT05765058: The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial

Not yet recruiting
N/A
136
Europe
Group A, Group B, Group C, Group D
University of Bern
Root Caries, NaF, SDF, Tooth Mousse
02/26
06/26
NCT06081868: RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda

Not yet recruiting
N/A
610
Europe
Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene
University of Bern
Dental Caries, Dental Plaque, Dental Diseases, Dental Caries in Children, Oral Disease, Oral Manifestations
09/26
09/26
Erdoes, Gabor
PAATICS, NCT06128330: Point-of-care Measurement of the Antifibrinolytic Activity of Tranexamic Acid in Cardiac Surgery

Recruiting
4
322
Europe
Tranexamic acid bolus 20 mg/kg, Tranexamic acid bolus 10 mg/kg, Tranexamic acid bolus 1 mg/kg, Tranexamic acid continuous infusion of 1 mg/kg/h in the low dose group
Insel Gruppe AG, University Hospital Bern
Antifibrinolytic Agents
12/25
12/26
NCT05460585: Cerebral Oxygenation Values in Healthy Adults Volunteers Measured With RheoPatch and NIRO-200NX

Completed
N/A
28
Europe
Cerebral oximetry using Rheopatch, Cerebral oximetry using NIRO-200NX
University Hospital Inselspital, Berne
Healthy, Adults
03/23
05/23
TRICS-IV, NCT04754022: Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery

Recruiting
N/A
1440
Europe, Canada, US, RoW
Restrictive Transfusion Strategy, Liberal transfusion strategy
Unity Health Toronto
Disorder, Heart, Postoperative, Cardiac Surgery
12/25
06/26
PLFICS, NCT06405516: Platelet Function After Cardiac Surgery.

Recruiting
N/A
40
Europe
Autologous blood cell salvage with in-house device, Autologous cell salvage with i-Sep SAME device
Insel Gruppe AG, University Hospital Bern, University Hospital, Geneva, University of Zurich
Platelet Dysfunction
12/24
01/25
Wolf, Thomas
DREAM-T2D, NCT04854512 / 2020-000763-23: Investigational Study of Delayed Release Metformin

Suspended
3
675
Europe, Canada, US, RoW
Metformin DR, ANJ900, MetDR, Metformin IR, Metformin DR Placebo, Metformin IR placebo
Anji Pharma
Diabetes Mellitus, Type 2
12/23
06/24
SHASTA-4, NCT06347016: Study of Plozasiran in Adults With Severe Hypertriglyceridemia

Recruiting
3
300
Europe, Canada, US, RoW
Plozasiran Injection, ARO-APOC3, Placebo
Arrowhead Pharmaceuticals
Severe Hypertriglyceridemia
07/26
10/26
VICTORION-1 PREVENT, NCT05739383: A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Active, not recruiting
3
14013
Europe, Canada, US, RoW
Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, KJX839, Placebo in 1.5ml
Novartis Pharmaceuticals
Primary Prevention of Atherosclerotic Cardiovascular Disease
04/29
04/29
NCT06081868: RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda

Not yet recruiting
N/A
610
Europe
Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene
University of Bern
Dental Caries, Dental Plaque, Dental Diseases, Dental Caries in Children, Oral Disease, Oral Manifestations
09/26
09/26
Berger, Thomas
NCT04277598: A Study to Evaluate Safety and Efficacy of APO-2 at Three Different Doses in Patients With Diabetic Foot Ulcer

Completed
1/2
159
Europe, RoW
APO-2, Placebo
Aposcience AG, FGK Clinical Research GmbH
Diabetic Foot Ulcer (DFU)
12/23
12/23
OPTIMIZE, NCT04879641: Optimizing Cognitive-behavioral Therapy for Social Anxiety Disorder Using the Factorial Design

Completed
N/A
464
Europe
Exposure, Attention Training, Cognitive Restructuring, Psychoeducation
University of Bern, University of Luebeck
Social Anxiety Disorder (Social Phobia)
10/23
02/24
SOPHIE, NCT04782102: Online-intervention for Prevention and Treatment of Social Anxiety in Adolescents

Completed
N/A
128
Europe
SOPHIE Intervention
University of Bern
Social Anxiety, Social Anxiety Disorder
12/23
03/24
Sui, NCT05651737: App-based Psychosocial Intervention to Enhance Quality of Life in Arabic-speaking Refugees Residing in Switzerland

Completed
N/A
170
Europe
Sui App (SRK)
University of Bern, Swiss Transfusion SRC, Freie Universität Berlin
Quality of Life, Stigma, Social, Depression, PTSD, Anxiety
03/24
03/24
PRIVATE, NCT06465589: Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications

Recruiting
N/A
452
Europe
JOURNeY anonymous, JOURNeY standard
University of Bern
Social Anxiety
02/26
02/26
Stähli, Alexandra
NCT05676268: Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension

Recruiting
N/A
70
Europe
Implant-supported fixed dental prostheses with cantilever extension
University of Bern
Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
09/23
12/23
NCT06676826: Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen

Not yet recruiting
N/A
80
Europe
Infrabony defects will be filled with a volume-stable collagen matrix (VCMX), VCMX, Infrabony defects will be filled treated with a deproteinized bovine bone mineral with 10% collagen, DBBM
University of Bern
Periodontal Diseases
06/26
12/27
PRF, NCT06679283: Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin

Not yet recruiting
N/A
40
Europe
Open flap debridement with a chemo-electric device + PRF, Open flap debridement with a chemo-electric device alone (control)
University of Bern
Peri-Implantitis, Bone Resorption, Platelet-Rich Fibrin
12/26
12/27
Romero, Maria
OFA_GAL_21, NCT05887258 / 2021-003245-38: Opioid-free Vs Traditional Balanced Anesthesia in Laparoscopic Colorectal Surgery

Completed
3
120
Europe
Opioid free anesthesia, OFA, Opioid based Anesthesia, Traditional anesthesia
Unai Ortega Mera, Osakidetza
Colorectal Surgery
05/24
06/24
OLE_NEAT, NCT06664853: Open-Label Extension of EryDex Study IEDAT-04-2022

Recruiting
3
106
Europe, US
Dexamethasone sodium phosphate
Quince Therapeutics S.p.A., Biotrial
Ataxia Telangiectasia
11/26
11/26
NCT06673056: A Pivotal Study of N-Acetyl-L-Leucine on Ataxia-Telangiectasia (A-T)

Not yet recruiting
3
60
Europe, US
N-Acetyl-L-Leucine, IB1001, levacetylleucine, Placebo
IntraBio Inc
Ataxia-Telangiectasia, Ataxia-Telangiectasia (A-T)
12/27
06/28
PHY1802, NCT04249492: PMCF Study on EDOF (Isopure) vs Monofocal (Micropure) IOL

Active, not recruiting
N/A
244
Europe, RoW
IOL implantation experimental (Isopure 1.2.3.), IOL implantation active comparator (Micropure 1.2.3.)
Beaver-Visitec International, Inc., targomedGmbH
Cataract, Lens Opacities
02/23
06/24
Hirsch, Hans
Shingr'HIV, NCT05575830: Immune Response of Shingrix Vaccine in People Living With HIV (> 50 y.o.) Compared to Age-matched Controls

Recruiting
4
225
Europe
Recombinant Zoster Vaccine, (Shingrix® )
Calmy Alexandra
RZV Vaccine (Shingrix ®)
09/24
09/25
NCT04351503: A Systems Approach to Predict the Outcome of SARS-CoV-2 in the Population of a City; COVID-19

Completed
N/A
126586
Europe
Study A, Study B, Study C, Study D
University Hospital, Basel, Switzerland, sciCORE University of Basel, Leonhard Med IT ETH Zurich, Swiss Institute of Bioinformatics
SARS Coronavirus (SARS-CoV-2) Infection
07/22
07/22
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens

Recruiting
N/A
10000
Europe
Analysis of Bacterial Genome
University Hospital, Basel, Switzerland, Swiss National Science Foundation
Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens
12/29
12/29
Schimmel, Martin
NCT06138392: Long-term Study in Early Loaded Hydrophilic Surface Implants

Completed
N/A
12
Europe
Dental implant (ELEMENT RC INICELL, Thommen Medical)
University of Bern
Dental Implant
09/21
12/21
SMIS, NCT04760457: Mandibular Overdentures Retained by Mini Implants: a Clinical Trial Comparing Different Surgical and Loading Protocols

Completed
N/A
74
RoW
Implant placement with flapped surgery, Implant placement with flapless surgery, Implant immediate loading, Implant delayed loading
Universidade Federal de Goias, ITI International Team for Implantology, Switzerland, Institut Straumann AG
Edentulous Mouth, Complete Edentulism
11/22
11/22
NCT03837158: Titanium Zirconium (TiZr) Mini Implants

Active, not recruiting
N/A
72
Europe
early loading, immediate loading
University of Bern
Dental Implants
09/24
08/33
NCT06335628: Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix

Recruiting
N/A
38
Europe
Geistlich Fibro-Gide®
University of Bern
Connective Tissue Graft, Volume Collagen Matrix Xenograft
04/26
04/29
T-bridge, NCT06099717: Clinical Performance of Dual-cantilevered Single-implant Bridge

Recruiting
N/A
50
RoW
Dual-cantilevered implant bridge, 3-unit iFDP
University of Bern, ITI International Team for Implantology, Switzerland
Dental Implant Failed
10/25
10/26
Leib, Stephen
PSSS_digital, NCT04130789: Personalized Swiss Sepsis Study

Recruiting
N/A
17500
Europe
compare data patterns by data-driven algorithms to determine sepsis, compare data patterns by data-driven algorithms to predict sepsis-related mortality
University Hospital, Basel, Switzerland, Swiss Personalized Health Network (SPHN), Personalized Health and Related Technologies (PHRT) initiative of ETH Zürich
Sepsis
06/22
06/23
NCT04280354: Molecular Biomarkers for Sepsis

Terminated
N/A
3
Europe
compare data patterns by data-driven algorithms to determine sepsis, compare data patterns by data-driven algorithms to predict sepsis-related mortality
University Hospital, Basel, Switzerland, Swiss Personalized Health Network (SPHN), Personalized Health and Related Technologies (PHRT) initiative of ETH Zürich
Sepsis, Severe Community-acquired Pneumonia (sCAP), Infection, Bacterial
07/22
07/22
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens

Recruiting
N/A
10000
Europe
Analysis of Bacterial Genome
University Hospital, Basel, Switzerland, Swiss National Science Foundation
Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens
12/29
12/29
Krieger, Tobias
SOLUS-D, NCT04655196: Evaluation of the Efficacy of Two Internet-based Self-help Interventions for Loneliness.

Completed
N/A
243
Europe
SOLUS-D + weekly feedback by a coach, SOLUS-D + weekly automated messages
University of Bern, Swiss National Science Foundation
Loneliness
11/22
09/23
Berzigotti, Annalisa
NCT05470205: Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal

Recruiting
3
660
Europe, US
SHAPE measurement (Sonazoid ultrasoud contrast agent), Sonazoid, SHAPE measurement (Definity ultrasoud contrast agent), Definity
Thomas Jefferson University, University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Bern
Liver Diseases, Portal Hypertension
02/26
04/26
CPMX2, NCT06544161: EJV Occlusion Pressure Measurement to Assess Intravascular Volume in Cirrhotic Patients During IV Albumin Substitution

Recruiting
N/A
20
Europe
CPMX2
Insel Gruppe AG, University Hospital Bern, Compremium AG
Liver Cirrhosis
06/25
06/25
SSCiCoS, NCT06092385: SASL Swiss Cirrhosis Cohort

Recruiting
N/A
3000
Europe
Data collection
University Hospital, Basel, Switzerland
Liver Cirrhosis
01/33
01/33
NCT04615091: Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery

Recruiting
N/A
250
Europe, Canada, US, RoW
Azienda Ospedaliera Universitaria Integrata Verona
Advanced Chronic Liver Disease, Surgery--Complications
10/21
08/22
NCT05479721: LITMUS Imaging Study

Active, not recruiting
N/A
450
Europe, US
University of Oxford, Newcastle University, University of Nottingham, University of Cambridge, University of Seville, Pinnacle Clinical Research, PLLC, ICAN Nutrition Education and Research, Assistance Publique - Hôpitaux de Paris, University of Angers, University of Palermo, University of Turin, Italy, University Medical Center Mainz, University of Helsinki, University of Bern, Linkoeping University, Perspectum, Antaros Medical, Resoundant Inc, Pfizer, Novartis, Takeda, Boehringer Ingelheim, Intercept Pharmaceuticals, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver, Steatosis of Liver
10/24
10/24
Nabecker, Sabine
NCT03759210: Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland

Recruiting
N/A
1000
Europe
Insel Gruppe AG, University Hospital Bern
Resuscitation, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest
12/23
06/24
PAS-EDU-RCD, NCT06368570: The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery

Recruiting
N/A
30
Canada
Interview, Interview questions
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Well-Being, Psychological
12/24
12/24
PAS-EDU-NLA, NCT06368583: The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analgesia

Recruiting
N/A
30
Canada
Interview, Interview questions
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Well-Being, Psychological
12/24
12/24
PAS-EDU-uCD-GA, NCT06589661: The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery Under General Anesthesia to Inform Anesthetic Practice

Recruiting
N/A
15
Canada
Interview
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Psychological Well Being
07/25
07/25
PAS-EDU-uCD-NA, NCT06589687: The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery Under Neuraxial Anesthesia to Inform Anesthetic Practice

Recruiting
N/A
25
Canada
Interview
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Psychological Well Being
07/25
07/25
Streit, Sven
DROPIT, NCT06129474: Deprescribing Inappropriate Proton Pump Inhibitors

Recruiting
N/A
400
Europe
Proton Pump Inhibitor deprescribing tool
University of Bern, Swiss National Science Foundation, University of Zurich, University of Basel, Insel Gruppe AG, University Hospital Bern, Patientenstelle Zürich, Patientenstelle Basel, Centre Hospitalier Universitaire Vaudois
Inappropriate Prescribing, Reflux Disease, Proton Pump Inhibitors
04/27
12/27
Perreten, Vincent
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens

Recruiting
N/A
10000
Europe
Analysis of Bacterial Genome
University Hospital, Basel, Switzerland, Swiss National Science Foundation
Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens
12/29
12/29
Nissen, Christoph
NCT05408013: The Prevalence of Insomnia in Patients With Psychiatric Disorders

Recruiting
N/A
500
Europe
University of Bern, Universitätsklinikum Freiburg Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Schleswig-Holstein Klinik für Psychiatrie und Psychotherapie, Schlafzentrum Pfalzklinikum Klingenmünster, Klinik und Poliklinik für Psychiatrie und Psychotherapie Leipzig, Zentralinstitut für Seelische Gesundheit Mannheim, Privatklinik Meiringen, Universitätsklinik für Psychiatrie und Psychotherapie, PMU Nürnberg, LWL-Klinik Paderborn, Klinik für Psychiatrie und Psychotherapie der Universität Regensburg, Kompetenzzentrum Schlafmedizin Charité - Campus Benjamin Franklin, Klinikum Ingolstadt (withdrawal of participation)
Insomnia
03/25
03/25
SLEEPexpert, NCT05408078: Become Your Own a Behavioral Treatment Program for Insomnia in Patients With Psychiatric Disorders

Recruiting
N/A
60
Europe
SLEEPexpert, TAU plus sleep monitoring
University of Bern
Insomnia Disorder
12/24
12/24
NCT04276064: Modulation of Sleep Perception Through Auditory Closed-loop Stimulation of Brain Oscillatory Activity

Completed
N/A
60
Europe
Auditory closed-loop stimulation: slow oscillation boosting, Auditory closed-loop stimulation: slow oscillation disruption, Sham stimulation
Christoph Nissen
Sleep, Insomnia
02/24
02/24
NCT06443216: Sleep Modulation to Treat Depression

Recruiting
N/A
60
Europe
Auditory closed-loop stimulation, Sham stimulation
Christoph Nissen
Major Depressive Disorder, Healthy
07/26
07/26
Consiglio, Jolanda
EuroECMO-COVID, NCT04366921: European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO

Recruiting
N/A
150
Europe, RoW
Maastricht University Medical Center, European chapter of the Extracorporeal Life Support Organization, Erasmus Medical Center, Leiden University Medical Center, UMC Utrecht, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Papa Giovanni XXIII Hospital, Niguarda Hospital, Ospedale San Donato, Ospedale S. Giovanni Bosco, IRCCS Policlinico S. Matteo, The Mediterranean Institute for Transplantation and Advanced Specialized Therapies, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Ospedale dell'Angelo, Venezia-Mestre, University Hospital, Udine, Italy, San Gerardo Hospital, Ospedali Riuniti Ancona, San Camillo Hospital, Rome, San Giorgio Clinic, GVM Care & Research, San Raffaele University Hospital, Italy, Ospedale San Bortolo di Vicenza, Klinik Hirslanden, Zurich, University of Zurich, Cardiocentro Ticino, Vilnius University Hospital Santaros Klinikos, Universitätsklinikum Düsseldorf, Klinikum Nürnberg, Hannover Medical School, Heart Center Leipzig - University Hospital, University Hospital Regensburg, University Hospital, Essen, German Heart Center, University Hospital, Aachen, University Heart Center Freiburg - Bad Krozingen, Klinikum Kassel, General University Hospital, Prague, Universitaire Ziekenhuizen Leuven, Onze Lieve Vrouwziekenhuis Aalst, Erasme University Hospital, University Hospital, Antwerp, Hôpital Civil Marie Curie de Charleroi, University Hospital, Ghent, Centre Hospitalier Universitaire Saint Pierre, Hospital Vall d'Hebron, Hospital Universitario Ramon y Cajal, Hospital Miguel Servet, Henri Mondor University Hospital, Hospices Civils de Lyon, Pitié-Salpêtrière Hospital, Rennes University Hospital, Guy's and St Thomas' NHS Foundation Trust, Karolinska University Hospital, Hospital Sao Joao, Medical University of Warsaw, Universitätskliniken Innsbruck, Medical University of Vienna, University Hospital, Alexandroupolis, Novosibirsk City Hospital #2, City Clinical Hospital No. 67, Moscow, Russia, City Hospital No 40, Saint Petersburg, Russia, Krasnodar Regional Hospital no 1, Kemerovo Regional Clinical Cardiological Center named after academician L.S. Barbarash, City Hospital No 41, Ekaterinburg, Russia, G. Pasquinucci Heart Hospital, Massa, Charles University, Czech Republic, University Hospital, Bordeaux, Bambino Gesù Hospital and Research Institute, Policlinico Hospital Milan, Gaslini Children's Hospital, Children's Medical Hospital, University of Essen, Essen, Germany, University Hospital, Geneva, Newcastle-upon-Tyne Hospitals NHS Trust, Paediatric Intensive Care Glasgow, Paris South University Hospitals, University of Groningen, Great Ormond Street Hospital for Children NHS Foundation Trust, Hospital Sant Joan de Deu, Heim Pal Children's Hospital, University Hospital, Montpellier, Royal Brompton & Harefield NHS Foundation Trust, Lund University Hospital, Landesklinikum Sankt Polten, Chelyabinsk Regional Clinical Hospital, ECMO Centers Israel, Copenhagen University Hospital at Herlev, Ospedale M. Bufalini Cesena, A.O.U. Città della Salute e della Scienza - Molinette Hospital, Mauriziano Umberto I Hospital, University of Bern, University Hospital, Basel, Switzerland, University of Lausanne Hospitals, University Hospital Tuebingen, Universitätsklinikum Köln, Chirec, Universitair Ziekenhuis Brussel, Centre Hospitalier Universitaire de Liège, La Louvière Hopital, Leicester Royal Infirmary NHS Trust
COVID, SARS-CoV-2, ARDS, Human, Refractory Hypoxemia, Cardiogenic Shock, Septic Shock, Extracorporeal Membrane Oxygenation
04/22
04/22
Fonseca, Manrique
NCT06335628: Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix

Recruiting
N/A
38
Europe
Geistlich Fibro-Gide®
University of Bern
Connective Tissue Graft, Volume Collagen Matrix Xenograft
04/26
04/29
Goutaki, Myrofora
EPIC-PCD, NCT04611516: The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients

Recruiting
N/A
1000
Europe
University of Bern, Bicetre Hospital, Centre Hospitalier Intercommunal Creteil, University Hospital Southampton NHS Foundation Trust, Universitaire Ziekenhuizen KU Leuven, Amsterdam UMC, location VUmc, University of Cyprus, Hacettepe University, Marmara University, Hospital Universitario La Fe, Insel Gruppe AG, University Hospital Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/30
12/40
iPCD, NCT03517865: International Primary Ciliary Dyskinesia Cohort

Recruiting
N/A
5000
Europe
University of Bern, European Commission, Swiss National Science Foundation, University of Southampton, Pierre and Marie Curie University, Bar-Ilan University, Israel, University of Padova, University Hospital, Gasthuisberg, Oslo University Hospital, Amsterdam UMC, location VUmc, Royal Brompton & Harefield NHS Foundation Trust, Marmara University, Ruhr University of Bochum, Genetic Disorders of Mucociliary Clearance Consortium, Institute of Tuberculosis and Lung Disorders, Rabka Poland, University of Sydney, Copenhagen University Hospital, Denmark, University Hospital Muenster, Hannover Medical School, Hospital de Niños R. Gutierrez de Buenos Aires, University of Cyprus, Medical Centre Dr Dragisa Misovic, Hacettepe University, University Hospital, Motol, Clinica de neumologia pediatrica Compensar, Attikon Hospital, University of Leicester
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/50
12/80
SPCDR, NCT03606200: Swiss Primary Ciliary Dyskinesia Registry

Recruiting
N/A
800
Europe
University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/80
12/80
Roccuzzo, Andrea
NCT05676268: Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension

Recruiting
N/A
70
Europe
Implant-supported fixed dental prostheses with cantilever extension
University of Bern
Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
09/23
12/23
NCT06676826: Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen

Not yet recruiting
N/A
80
Europe
Infrabony defects will be filled with a volume-stable collagen matrix (VCMX), VCMX, Infrabony defects will be filled treated with a deproteinized bovine bone mineral with 10% collagen, DBBM
University of Bern
Periodontal Diseases
06/26
12/27
Lam, Yin Ting
EPIC-PCD, NCT04611516: The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients

Recruiting
N/A
1000
Europe
University of Bern, Bicetre Hospital, Centre Hospitalier Intercommunal Creteil, University Hospital Southampton NHS Foundation Trust, Universitaire Ziekenhuizen KU Leuven, Amsterdam UMC, location VUmc, University of Cyprus, Hacettepe University, Marmara University, Hospital Universitario La Fe, Insel Gruppe AG, University Hospital Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
12/30
12/40
Marchal-Crespo, Laura
NCT04759976: Optimize Motor Learning to Improve Neurorehabilitation

Recruiting
N/A
250
Europe
Robotic motor training
University of Bern
Stroke, Neurologic Disorder
07/23
12/23
Schmidt, Stefanie J
SOPHIE, NCT04782102: Online-intervention for Prevention and Treatment of Social Anxiety in Adolescents

Completed
N/A
128
Europe
SOPHIE Intervention
University of Bern
Social Anxiety, Social Anxiety Disorder
12/23
03/24
EMPATIA, NCT05934019: Efficacy of a Transdiagnostic Online Prevention Approach in Adolescents

Active, not recruiting
N/A
152
Europe
EMPATIA 1
University of Bern
Mental Health Issue, Transdiagnostic Mechanisms, Adolescent Psychology, Prevention, Online Intervention, Psychological Intervention, Mental Disorder in Adolescence, Subclinical
03/25
09/25
Walder, Noemi
SOPHIE, NCT04782102: Online-intervention for Prevention and Treatment of Social Anxiety in Adolescents

Completed
N/A
128
Europe
SOPHIE Intervention
University of Bern
Social Anxiety, Social Anxiety Disorder
12/23
03/24
Amrein, Melanie Dr
NCT04830761: Behavior Change in Context to Contain the Spread of COVID-19

Completed
N/A
425
Europe
Motivation, Habit, Social
University of Bern, Ursula Wirz Stiftung
Hand Hygiene
12/22
04/23
 

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