| Zelefsky, Michael J |
NCT03056638: Trial of ADT and SBRT Versus SBRT for Intermediate Prostate Cancer |
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| Terminated | 3 | 56 | US | Degarelix, stereotactic body radiosurgery (SBRT) | Memorial Sloan Kettering Cancer Center, Ferring Pharmaceuticals, University of Texas Southwestern Medical Center, University of Michigan | Prostate Cancer | 08/23 | 08/23 | | |
NCT06397703: ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer |
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| Recruiting | 3 | 392 | US | Leuprolide, Degarelix or Relugolix, Stereotactic body radiation therapy/radiosurgery (SBRT) | NYU Langone Health | Prostate Cancer | 04/28 | 04/28 | | |
NCT01223248: Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy |
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| Active, not recruiting | 3 | 220 | Europe, US | IGIMRT using a single dose of 24 Gy, IGIMRT 27 Gy in 3 fractions | Memorial Sloan Kettering Cancer Center, University of Pisa, University of California, San Francisco, The Champalimaud Centre, Lisbon, Portugal | Melanoma, Ovarian Cancer, Sarcoma, Bone, CNS-Spinal CD/MEMBR, NOS, Lymph Nodes, Soft Tissue | 10/25 | 10/25 | | |
NCT05169970: A Study of Stereotactic Body Radiation Therapy (SBRT) Without Androgen Deprivation Therapy (ADT) in People With Unfavorable Intermediate-Risk Prostate Cancer |
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| Recruiting | 2 | 215 | US | Stereotactic Body Radiation Therapy (SBRT) | Memorial Sloan Kettering Cancer Center | Prostate Cancer | 12/25 | 12/25 | | |
NCT02312401: Evaluation of Treatment Response Using Multiparametric MRI After Prostate Radiotherapy |
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| Active, not recruiting | 2 | 120 | US | multi-parametric MRI(MP-MRI), dynamic contrast-enhanced MRI (DCE), biopsy | Memorial Sloan Kettering Cancer Center | Prostate Cancer | 12/25 | 12/25 | | |
NCT05133440: A Study of Stereotactic Body Radiation Therapy and Radium (Ra-223) Dichloride in Prostate Cancer That Has Spread to the Bones |
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| Active, not recruiting | 2 | 12 | US | Radium dichloride, Ra-223, PET Scan, NaF PET | Memorial Sloan Kettering Cancer Center | Prostate Cancer | 11/27 | 11/27 | | |
NCT03269422: Radiotherapy to the Prostate and Dominant Intra-Prostatic Lesion (DIL) |
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| Active, not recruiting | 1 | 35 | US | MR-based image-guided, intensity-modulated radiotherapy | Memorial Sloan Kettering Cancer Center | Prostate Cancer | 08/25 | 08/25 | | |
NCT05079698: A Study of Stereotactic Body Radiotherapy and 177Lu-PSMA-617 for the Treatment of Prostate Cancer |
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| Recruiting | 1 | 27 | US | 177Lu-PSMA-617, Stereotactic Body Radiotherapy (SBRT) | Memorial Sloan Kettering Cancer Center, Novartis Pharmaceuticals | Prostate Cancer | 10/25 | 10/25 | | |
NCT00911118: Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer |
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| Active, not recruiting | 1 | 120 | US | Hypofractionated, image-guided, intensity-modulated external beam radiation | Memorial Sloan Kettering Cancer Center, Montefiore Medical Center | Prostate Cancer, Adenocarcinoma | 05/25 | 05/25 | | |
TUMORNATOR I, NCT06542757: Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy |
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| Not yet recruiting | N/A | 91 | US | 1.5 T Elekta Unity MR-Linac system, Hydrogel rectal spacer (SpaceOAR) | NYU Langone Health | Prostate Cancer | 11/25 | 11/27 | | |
| Prato, Stefano Del |
SURPASS-EARLY, NCT05433584: A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes |
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| Active, not recruiting | 4 | 780 | Europe, Canada, US, RoW | Tirzepatide, LY3298176, Antihyperglycemic medication | Eli Lilly and Company | Type 2 Diabetes | 10/25 | 11/27 | | |
| Recruiting | N/A | 300 | Europe | Digital Health, Standard care | University of Pisa, University of Florence, Azienda Ospedaliero, Universitaria Pisana | PreDiabetes | 10/24 | 04/25 | | |
| Solini, Anna |
NCT05936151: A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes |
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| Recruiting | 2 | 120 | Europe, Canada, US | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Overweight or Obesity, CKD, Type 2 Diabetes | 11/25 | 11/25 | | |
UTI-flog, NCT04735042: SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections. |
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| Recruiting | N/A | 60 | Europe | Empagliflozin / Linagliptin or Dapagliflozin/Saxagliptin Pill, Glyxambi or Qtern, Empagliflozin or Dapagliflozin Pill, Jardiance or Forxiga | University of Pisa | Type 2 Diabetes, Urinary Tract Infections | 10/21 | 04/22 | | |
| Masi, Gianluca |
FIRST-308, NCT05948475: Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma |
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| Recruiting | 3 | 200 | Europe, US, RoW | Tinengotinib 8 mg, Tinengotinib 10 mg, Physician's Choice | TransThera Sciences (Nanjing), Inc. | Cholangiocarcinoma | 05/26 | 08/26 | | |
| Recruiting | 2 | 46 | Europe | 166Holmium TARE, Cetuximab, Panitumumab, 5-Fluorouracil, Bevacizumab, Capecitabine | Gruppo Oncologico del Nord-Ovest | Colorectal Cancer Metastatic | 11/26 | 02/27 | | |
TriComB, NCT04564898: Trifluridine/Tipiracil in Combination With Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients. |
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| Active, not recruiting | 1/2 | 48 | Europe | Capecitabine, Bevacizumab, Trifluridine/Tipiracil | Gruppo Oncologico del Nord-Ovest | Colorectal Cancer Metastatic | 05/24 | 05/25 | | |
NCT05630937 / 2020-001002-26: Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy |
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| Completed | 1/2 | 31 | Europe, US | NMS-01940153E | Nerviano Medical Sciences | Unresectable Hepatocellular Carcinoma (HCC) | 01/24 | 08/24 | | |
NCT05301465: Predictive Role of Circulating Angiogenic Factors for Second-line Paclitaxel and Ramucirumab. |
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| Recruiting | N/A | 50 | Europe | | University of Pisa | Gastric Cancer Stage IV | 11/22 | 06/23 | | |
| Antonelli, Alessandro |
NCT05830747: Effect of Pre-emptive Dose of Prednisone Versus Placebo in Impacted Third Molar Surgery |
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| Completed | 4 | 34 | Europe | Prednisone, Placebo | University Magna Graecia | Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos, Tooth Avulsion | 10/22 | 12/22 | | |
NCT05002998: TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study |
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| Active, not recruiting | 4 | 313 | Europe, US | Teprotumumab, TEPEZZA, Placebo, Saline Solution | Amgen | Thyroid Eye Disease | 04/26 | 04/26 | | |
| Recruiting | 3 | 112 | Europe, US | ONCOFID P-B (PACLITAXEL-HYALURONIC ACID) | Fidia Farmaceutici s.p.a. | Bladder Carcinoma in Situ (CIS) | 11/25 | 11/27 | | |
OLIGOS, NCT06273345: Impact of Treatment on Primary Tumour in Patients With Newly Diagnosed Oligometastatic Neoplasia of the Prostate |
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| Recruiting | N/A | 150 | Europe | | Istituto Oncologico Veneto IRCCS | Oligometastatic Prostate Carcinoma | 01/25 | 01/25 | | |
| Recruiting | N/A | 30 | Europe | DaVinci RAPN, Hugo RAS RAPN | Azienda Ospedaliera Universitaria Integrata Verona | Renal Carcinoma | 12/24 | 06/25 | | |
| Recruiting | N/A | 150 | Europe | DaVinci RARP, DaVinci® Surgical System, Hugo RARP, Hugo™ RAS System, Versius RARP, Versius® Robotic Surgery System | Azienda Ospedaliera Universitaria Integrata Verona | Prostate Cancer | 03/24 | 09/24 | | |
Hydeal Cyst, NCT06245603: A Study to Evaluate Efficacy and Safety of ® Intravesical Instillations in Patients Treated With Intravesical Chemotherapy or Immunotherapy in Non-muscle Invasive Bladder Cancer |
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| Recruiting | N/A | 200 | Europe | Hydeal Cyst® | Istituto Oncologico Veneto IRCCS, Fidia Farmaceutici s.p.a. | Non-muscle Invasive Bladder Cancer | 12/26 | 06/27 | | |
| Recruiting | N/A | 15000 | Europe | Standard treatment | University of Roma La Sapienza, Italian Thyroid Cancer Observatory (ITCO) Foundation, Catholic University of the Sacred Heart | Thyroid Neoplasms | 01/25 | 01/25 | | |
AUR87A, NCT04006405: AURORAX-0087A: GAG Scores for Surveillance of Recurrence in Leibovich Points ≥5 Non-metastatic ccRCC |
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| Active, not recruiting | N/A | 280 | Europe, Canada, US | GAG score | Elypta | Clear Cell Renal Cell Carcinoma | 05/25 | 12/25 | | |
NCT05479422: Optilume Registry for Treatment of Stricture of the Anterior Urethra |
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| Recruiting | N/A | 150 | Europe | | European Association of Urology Research Foundation, Laborie Medical Technologies Inc. | Anterior Urethral Stricture, Male | 08/29 | 08/29 | | |
| Recruiting | N/A | 10000 | Europe, Japan, US, RoW | Partial Nephrectomy (PN), Radical Nephrectomy (RN), Ablation therapy (AT), Active Surveillance (AS) | Azienda Ospedaliero-Universitaria Careggi, Società Italiana di Urologia (SIU), Italian Group for Advanced Laparo-Endoscopic and Robotic Urologic Surgery (AGILE) | Kidney Cancer | 12/23 | 12/28 | | |
| Coordinator, Research |
| Recruiting | 4 | 292 | US | Amnion-Intermediate-Chorion, AIC, Amnion-Chorion-Amnion, ACA, Standard of Care, SOC | Cellution Biologics, SerenaGroup, Inc., LifeCell | Diabetic Foot Ulcer, Venous Leg Ulcer | 12/26 | 07/27 | | |
| Recruiting | 4 | 2650 | US | Zoledronic Acid 5Mg/Bag 100Ml Inj, Reclast, Placebo | California Pacific Medical Center Research Institute, National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation | Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies | 10/25 | 10/25 | | |
NCT05078827: Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis |
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| Completed | 3 | 458 | US | Test Product (A): Fluorouracil Cream, 5% topical cream, Experimental, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Active Comparator, Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India, Placebo Comparator | Encube Ethicals Pvt. Ltd., CBCC Global Research | Actinic Keratoses | 11/22 | 12/22 | | |
| Completed | 3 | 558 | US | ReMMi-D Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 05/24 | | |
OPERA-T, NCT05238116 / 2021-004554-32: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis ( Study) |
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| Recruiting | 3 | 123 | Europe, Canada, US, RoW | PC945, Placebo | Pulmocide Ltd | Refractory IPA | 03/26 | 04/26 | | |
NCT06004388: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) |
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| Completed | 3 | 110 | US | Click Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 06/24 | | |
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain |
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| Active, not recruiting | 3 | 1800 | US | Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices | Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Knee Osteoarthritis | 03/25 | 03/25 | | |
CONVOKE, NCT05838625: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Recruiting | 3 | 432 | US | Digital Therapeutic | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 06/25 | 07/25 | | |
NCT06067984: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Active, not recruiting | 3 | 75 | US | Study App | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia, Negative Symptoms in Schizophrenia | 04/25 | 05/25 | | |
| Active, not recruiting | 2/3 | 1500 | US | ABBV-CLS-7262, DNL343 | Merit E. Cudkowicz, MD, Massachusetts General Hospital | Amyotrophic Lateral Sclerosis | 07/25 | 04/26 | | |
NCT06365437: A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation |
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| Completed | 2 | 33 | Europe | TCD601, Siplizumab, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 12/24 | 12/24 | | |
| Recruiting | 2 | 25 | Europe, Canada, Japan, US, RoW | nedosiran, DCR-PHXC | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | Primary Hyperoxaluria, Primary Hyperoxaluria Type 1, Primary Hyperoxaluria Type 2, Primary Hyperoxaluria Type 3 | 12/24 | 12/24 | | |
NCT03651700: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia |
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| Completed | 2 | 86 | US | Active TMS, Sham TMS, CILT, Constraint Induced Language Therapy | H. Branch Coslett, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Aphasia | 08/24 | 08/24 | | |
CHASE, NCT05727878: Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED |
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| Recruiting | 2 | 90 | US, RoW | KPI-012, KPI-012 Vehicle | Combangio, Inc, Kala Pharmaceuticals, Inc. | Persistent Corneal Epithelial Defect | 03/25 | 10/25 | | |
NCT05733546: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder |
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| Recruiting | 2 | 102 | US | Psilocybin, COMP360 | COMPASS Pathways | Major Depressive Disorder | 10/24 | 11/24 | | |
NCT04270175: Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab |
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| Recruiting | 2 | 21 | US | Daratumumab SC, Faspro, Pomalidomide, Dexamethasone | Weill Medical College of Cornell University, Janssen Scientific Affairs, LLC | Amyloid, AL Amyloidosis, Refractory AL Amyloidosis | 12/25 | 12/29 | | |
NCT04803058: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE) |
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| Recruiting | 2 | 18 | US, RoW | TCD601 | ITB-Med LLC | Kidney Transplantation | 03/27 | 03/30 | | |
| Not yet recruiting | 2 | 20 | US | Sodium Thiosulfate (STS) | Robyn T. Domsic, MD, MPH, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Systemic Sclerosis (SSc), Dermatomyositis, Mixed Connective Tissue Disease (MCTD), Calcinosis | 05/25 | 11/25 | | |
| Active, not recruiting | 2 | 96 | Europe | TCD601, Placebo | ITB-Med LLC | Diabetes Mellitus, Type 1 | 01/25 | 01/25 | | |
| Not yet recruiting | 2 | 30 | Canada | AMT-143 hydrogel containing containing ropivacaine, AMT-143, Ropivacaine, Placebo | AmacaThera Inc. | Hernia, Hernia, Abdominal | 03/26 | 05/26 | | |
| Recruiting | 2 | 90 | US | TCD601, siplizumab, belatacept, ATG, antithymocyte globulin, TAC, tacrolimus, MPA, mycophenolic acid, Corticosteroids | ITB-Med LLC | Renal Transplantation | 07/25 | 10/26 | | |
NCT04311632: A Dose Escalation Study in de Novo Renal Transplantation |
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| Completed | 2 | 13 | US | TCD601, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 10/23 | 10/23 | | |
NCT04464980: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD) |
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| Recruiting | 2 | 2190 | US | SL-BUP, sublingual buprenorphine, Suboxone, XR-BUP, extended-release buprenorphine, CAM2038, Brixadi, XR-NTX, extended-release naltrexone, Vivitrol, MM, MMR, MMD | NYU Langone Health, New York State Psychiatric Institute, Columbia University, Harvard Medical School (HMS and HSDM), Mclean Hospital, National Institute on Drug Abuse (NIDA), The Emmes Company, LLC | Opioid Use Disorder (OUD) | 07/26 | 12/26 | | |
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA) |
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| Recruiting | 2 | 18 | US | TCD601 | ITB-Med LLC | Kidney Transplantation | 07/27 | 07/30 | | |
NCT04892251: Ketamine Assisted Psychotherapy for Opioid Use Disorder |
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| Recruiting | 1/2 | 60 | US | MORE+KAP, MORE | University of Utah | Opioid-use Disorder | 12/23 | 05/24 | | |
NCT04482179: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease |
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| Completed | 1 | 23 | US | Active TMS, CILT, Constraint Induced Language Therapy, Sham TMS | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Alzheimer Disease | 08/24 | 08/24 | | |
AURORA, NCT06453668: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients |
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| Active, not recruiting | 1 | 48 | Europe | TCD601, siplizumab | ITB-Med LLC | ALS | 11/26 | 11/26 | | |
| Recruiting | 1 | 15 | US | PBA-0405, PB004.22.0405.aF | Pure Biologics S.A., Presage Biosciences | Head and Neck Squamous Cell Carcinoma, Soft Tissue Sarcoma Adult, Triple Negative Breast Cancer | 03/25 | 03/25 | | |
MST01-AZN-05, NCT06366451: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, AstraZeneca | Head and Neck Squamous Cell Carcinoma | 12/24 | 03/25 | | |
| Recruiting | 1 | 155 | US, RoW | OP-1250, Ribociclib, KISQALI®, Alpelisib, PIQRAY®, Everolimus | Olema Pharmaceuticals, Inc., Novartis | Metastatic Breast Cancer, Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer | 05/26 | 06/26 | | |
NCT06798454: Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC) |
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| Recruiting | 1 | 30 | RoW | PVT201, Navacim, Placebo, normal saline, 0.9% NaCl | Parvus Therapeutics, Inc., Avance Clinical Pty Ltd. | Primary Biliary Cholangitis (PBC) | 02/25 | 02/25 | | |
NCT04541108: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, Merck Sharp & Dohme LLC | Solid Tumor | 12/31 | 12/31 | | |
NCT06802328: Treatment Protocol: Intermediate-Size Patient Population Expanded Access |
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| Available | N/A | | US | Foralumab TZLS-401 50 µg | Tiziana Life Sciences LTD | Non-Active Secondary Progressive Multiple Sclerosis | | | | |
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing |
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| Recruiting | N/A | 260 | Canada | FGFR Testing | Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada | Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma | 03/25 | 05/25 | | |
| Completed | N/A | 199 | US | Cigarette flavor type, Experimental cigarette smoking | University of Oklahoma | Smoking, Cigarette | 12/22 | 01/23 | | |
NCT03869463: Computerized Cognitive Training in Young Adults With Depression |
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| Terminated | N/A | 28 | US | Computerized Cognitive Training, Control | Queens College, The City University of New York | Depressive Symptoms | 03/23 | 03/23 | | |
NCT03495011: MRI Characterization of Mammographically Detected DCIS |
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| Active, not recruiting | N/A | 122 | US | Breast MRI, Laboratory Biomarker Analysis, Oncotype Dx | University of Washington, National Cancer Institute (NCI), National Institutes of Health (NIH) | Breast Cancer, Stage 0 | 04/23 | 04/32 | | |
| Recruiting | N/A | 35 | US | MRI, blood draw, Clinical assessments | University of Vermont, National Institute of General Medical Sciences (NIGMS) | Stroke, Acute, Gait, Hemiplegic | 05/23 | 05/23 | | |
NCT04902339: Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain |
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| Recruiting | N/A | 75 | US | Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy | University of Utah | Chronic Pain Syndrome, Opioid Use | 05/23 | 08/23 | | |
NCT04088773: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease |
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| Active, not recruiting | N/A | 232 | US | blood biomarkers, stool biomarkers, MRI imaging | Children's Hospital Medical Center, Cincinnati, The Leona M. and Harry B. Helmsley Charitable Trust | Crohn Disease | 09/23 | 09/24 | | |
NCT06136936: A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia |
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| Completed | N/A | 53 | US | CT-156-C-001 | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 01/24 | 02/24 | | |
| Recruiting | N/A | 20 | US | Prototypes of breast shield and Freedom Double Electric Breast Pump | Momtech Inc. | Healthy, Breast Pumping | 09/24 | 11/24 | | |
NCT06136923: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer |
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| Completed | N/A | 194 | US | CT-100-D-004-A, CT-100-D-004-B | Click Therapeutics, Inc. | Multiple Sclerosis, Lung Cancer, Breast Cancer | 04/24 | 05/24 | | |
NCT05465395: Upper Cervical and Thoracic Chiropractic Adjustment |
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| Suspended | N/A | 40 | US | Upper Cervical Adjustemnt, Thoracic Adjustemnt | Life University | Stress | 11/23 | 11/23 | | |
| Completed | N/A | 314 | US | FemaSeed Localized Directional Insemination | Femasys Inc. | Infertility, Male Factor | 12/23 | 04/24 | | |
CT-100-D-003, NCT06275659: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis |
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| Active, not recruiting | N/A | 120 | US | CT-100-004-A, CT-100-004-B | Click Therapeutics, Inc. | Psoriasis, Atopic Dermatitis | 02/24 | 03/24 | | |
NCT05617300: Mindfulness-based Dementia Care Partner Program to Reduce Depressive Symptoms |
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| Completed | N/A | 130 | US | Mindfulness-Based Dementia Caregiving | HealthPartners Institute | Dementia | 12/23 | 03/24 | | |
NCT04685044: Testing a 32-channel Transmit/Receive MRI Head Array |
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| Active, not recruiting | N/A | 15 | Canada | IH 1Tx32Rx Head Array | Lawson Health Research Institute | Magnetic Resonance Imaging | 12/23 | 12/23 | | |
| Completed | N/A | 172 | US | Very low nicotine cigarettes | University of Oklahoma | Cigarette Smoking, Smoking Behaviors | 03/24 | 04/24 | | |
NCT03303248: Evaluation of Web-based Transition Education to Enhance Transition Readiness |
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| Active, not recruiting | N/A | 180 | US | Web-based Educational Intervention | University of Michigan, University of Nebraska | Congenital Heart Disease, Transition, Pediatric Congenital Heart Disease | 03/25 | 03/25 | | |
NCT05119842: APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study |
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| Recruiting | N/A | 30 | Europe, US | APrevent® VOIS-Implant | APrevent Biotech GmbH | Paralysis, Unilateral, Vocal Cord | 09/25 | 09/26 | | |
| Completed | N/A | 60 | US | alcohol beverage, Placebo beverage | University of Texas at Austin | Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder | 03/24 | 03/24 | | |
NCT04625959: Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder |
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| Active, not recruiting | N/A | 256 | US | Behavioral Therapy for Eating Disorders, MABT: Mindful Awareness, MABT: Values, MABT: Emotion Modulation, MABT: Distress Tolerance | Drexel University, National Institute of Mental Health (NIMH) | Bulimia Nervosa, Bulimia; Atypical, Binge-Eating Disorder, Binge-Eating and Purging Type Anorexia Nervosa, Binge Eating | 04/24 | 04/24 | | |
NCT06330246: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease |
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| Recruiting | N/A | 40 | US | Low oxalate fixed diets pre-colonization, Moderately high oxalate fixed diets pre-colonization, Colonization with Oxalobacter formigenes, Low oxalate fixed diets post-colonization, Moderately high oxalate fixed diets post-colonization | University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria | 12/30 | 12/31 | | |
NCT06331546: Gut Oxalate Absorption in Calcium Oxalate Stone Disease |
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| Recruiting | N/A | 80 | US | Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test | University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy | 12/30 | 12/31 | | |
SWAT, NCT06588101: Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU |
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| Recruiting | N/A | 160 | Canada | Written informed consent with infographic, Compensation | Lady Davis Institute, Canadian Institutes of Health Research (CIHR) | Family Members, Recruitment, Clinical Study, Retention, Recruitment of Participants, Study Enrollment, Retention of Participants, Compensation Incentives | 04/25 | 12/25 | | |
NCT06431386: Behavioural Activation Therapy and Esketamine for Resistant Depression |
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| Recruiting | N/A | 40 | Canada | Behavioural Activation (BA) Therapy, Esketamine | The Royal's Institute of Mental Health Research | Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major, Bipolar Disorder | 08/26 | 08/26 | | |
| Completed | N/A | 68 | US | Alcohol beverage, Placebo beverage | University of Texas at Austin | Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder | 06/24 | 06/24 | | |
NCT04279483: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments |
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| Completed | N/A | 336 | US | 7-11, CVS | Abramson Cancer Center at Penn Medicine, National Cancer Institute (NCI), New York University, Stanford University | Smoking, Tobacco, Smoking, Smoking, Cigarette | 06/24 | 06/24 | | |
NCT05884437: The Effects of Chiropractic in Adults With Metabolic Syndrome |
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| Suspended | N/A | 10 | US | Chiropractic adjustment | Life University | Metabolic Syndrome | 07/25 | 12/25 | | |
I-YMSC, NCT06657950: Treatments for Improving Mood in Women Survivors of Interpersonal Violence: A Community-Engaged Study-1.2 |
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| Recruiting | N/A | 15 | US | Integrative hatha yoga and mindful self-compassion | Butler Hospital, National Center for Complementary and Integrative Health (NCCIH) | Distress | 09/25 | 09/25 | | |
NCT06385392: Continuous Wearable Monitor for the Detection and Release of Freezing of Gait. |
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| Recruiting | N/A | 36 | US | Haptic module and insole device | HealthPartners Institute | Parkinson Disease | 05/25 | 05/25 | | |
NCT06172660: Real-World Effectiveness of Perinatal RSV Immunoprophylaxis |
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| Recruiting | N/A | 3750 | US | Nirsevimab, RSV vaccines | Yale University, National Institute of Allergy and Infectious Diseases (NIAID) | RSV Infection | 12/28 | 12/28 | | |
| Recruiting | N/A | 750 | Canada | Cardiac monitoring device | Population Health Research Institute | Atrial Fibrillation, Atrial Flutter | 08/26 | 12/26 | | |
| Recruiting | N/A | 62 | US | Morning Exercise | Rutgers, The State University of New Jersey | Sleep, Mood, Stress | 12/26 | 12/26 | | |
Lublin, NCT06217081: 3M™ Topical Tissue Adhesive Versus Commercially Available Tissue Adhesive for the Closure of Lacerations and Incisions |
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| Recruiting | N/A | 452 | US | 3M Topical Tissue Adhesive, Histoacryl® Blue Topical Skin Adhesive | Solventum US LLC, United States Department of Defense, The University of Texas Health Science Center at San Antonio, 3M | Trauma-related Wound, Surgical Incision, Surgical Wound, Laceration | 11/25 | 12/25 | | |
NCT03556683: Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics |
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| Completed | N/A | 22 | US | 3% Hypertonic Saline, 7% Hypertonic Saline | University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI) | Moderate to Severe Asthma | 06/24 | 06/24 | | |
| Recruiting | N/A | 581 | US | | CoMind Technologies Limited, Lindus Health | Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage, Encephalitis, Encephalopathy, Hydrocephalus, Stroke, Autoregulation | 10/25 | 10/25 | | |
| Recruiting | N/A | 50 | US | Pulmonary Valve Replacement Surgery | Autus Valve Technologies, Inc. | Congenital Heart Disease | 08/26 | 02/36 | | |
| Enrolling by invitation | N/A | 1642 | US | Biopsy strategy | University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis | 12/28 | 06/29 | | |
