| JOHNSON-ANSAH, Hyacinthe |
Predictor2, NCT03887156: Evaluation of a Donor Testing Kit for the Prediction of AGVHD in Patient Receiving a Peripheral Blood Stem Cell Allograft |
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| Recruiting | 2/3 | 227 | Europe | Ex vivo capacities of CD4neg INkT expansion of the peripheral blood donor with the Predictor test | Assistance Publique - Hôpitaux de Paris, SATT, SNC Graft Versus Host Disease, Imagine Institute, Axonal-Biostatem, CERBA laboratory | Acute Myeloid Leukemia in Remission, Lymphoma in Remission, Non-progressive Myeloproliferative Syndrome, Myelodysplasia With Stable Blasts is Cell Number and < 10% of Blastocysts, Acute Leukemia Biphenotypic in Remission, Acute Lymphoblastic Leukemia | 03/23 | 03/23 | | |
| Chantepie, Sylvain |
| Active, not recruiting | 3 | 66 | Europe | MaaT013 | MaaT Pharma, MaaT Pharma | Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD | 11/24 | 11/25 | | |
BIG-1, NCT02416388: Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR |
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| Recruiting | 2/3 | 3100 | Europe | Idarubicin, Daunorubicin, HD Cytarabine, Cyclosporine, Methotrexate, Mycophenolic acid (MPA), vosaroxin, ID cytarabine, Dexamethasone, Venetoclax | University Hospital, Angers | Acute Myeloid Leukemia (AML) | 07/25 | 01/32 | | |
PONAZA, NCT03895671: : A COMBINATION OF PONATINIB AND 5-AZACITIDINE IN CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE OR IN MYELOID BLAST CRISIS |
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| Recruiting | 2 | 40 | Europe | Ponatinib, Azacitidine | Versailles Hospital | CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE, CHRONIC MYELOGENOUS LEUKAEMIA IN MYELOID BLAST CRISIS | 12/23 | 12/24 | | |
| Active, not recruiting | 2 | 95 | Europe, US | Tamibarotene, Venetoclax, Venclexta, Azacitidine, Vidaza | Syros Pharmaceuticals, Syros Pharmaceuticals, Inc. | Acute Myeloid Leukemia | 04/28 | 04/28 | | |
| Completed | 2 | 42 | Europe | CPX-351 | French Innovative Leukemia Organisation, Acute Leukemia French Association, French Intergroup of Myeloproliferative syndromes | Acute Myeloid Leukemia, Myeloproliferative Syndrome | 10/23 | 12/23 | | |
PHOEBUS, NCT05762211: Oral Pooled Fecal Microbiotherapy to Prevent Allogeneic Hematopoietic Cell Transplantation Complications ( Trial) |
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| Recruiting | 2 | 387 | Europe | Pooled allogeneic fecal microbiotherapy, MaaT033, Placebo | MaaT Pharma | Transplant Complication | 10/26 | 02/27 | | |
HAPLO-EMPTY, NCT05126849: Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression |
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| Recruiting | 2 | 31 | Europe | Allogenic transplantation | Assistance Publique - Hôpitaux de Paris | Refractory Idiopathic Aplastic Anemia, Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation | 01/27 | 01/27 | | |
| Recruiting | 2 | 50 | Europe | Gemtuzumab ozogamicine - Cytarabine - Gilteritinib, Mylotarg - Aracytine - Xospata | Centre Antoine Lacassagne, Acute Leukemia French Association | AML | 03/27 | 03/27 | | |
ALFA2101, NCT05260528: CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics |
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| Recruiting | 2 | 210 | Europe | Cytarabine and Idarubicin, CPX-315 | Centre Hospitalier Universitaire de Nice, Jazz Pharmaceuticals, Acute Leukemia French Association | Acute Myeloid Leukemia | 10/27 | 10/27 | | |
FLUCLORIC, NCT05917405: Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT |
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| Recruiting | 2 | 302 | Europe | Fludarabine, Busulfan, ATG, Clofarabine | Nantes University Hospital | Acute Myeloid Leukemia in Remission | 09/28 | 09/28 | | |
SALMA, NCT05580861: Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatment |
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| Recruiting | 1/2 | 64 | Europe | Sulfasalazine | Assistance Publique - Hôpitaux de Paris | Acute Myeloid Leukemia | 11/25 | 12/26 | | |
ALFAPPP, NCT04777916: Prospective Non-interventional Study of Adult Patients With Acute Myeloid Leukemia (AML) |
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| Recruiting | N/A | 2500 | Europe | | Acute Leukemia French Association | Acute Myeloid Leukemia (AML) | 04/32 | 04/46 | | |
DECLAM, NCT03450512: Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy |
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| Recruiting | N/A | 170 | Europe | prospective study on digestive affections in an homogeneous cohort of hematological patients | Centre Hospitalier Universitaire, Amiens | Acute Myeloid Leukemia | 11/24 | 11/24 | | |
VENAZA, NCT06263387: Results From a French Temporary Utilization Authorization of First-line Acute Myeloid Leukemia (AML) Patients Ineligible for Intensive Chemotherapy (IC), Treated With Venetoclax Azacitidine |
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| Recruiting | N/A | 230 | Europe | | French Innovative Leukemia Organisation, Acute Leukemia French Association | AML, Adult | 12/24 | 03/25 | | |
NCT06045819: Relation Between Venetoclax Plasma Concentration and Remission in Adults With Acute Myeloid Leukemia (PREDICLAX) |
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| Recruiting | N/A | 100 | Europe | Blood sampling for venetoclax drug dosage (venous puncture), Biological: Capillary Blood sampling for venetoclax drug dosage with Volumetric Absorptive Microsampling (VAMS™) technology with Mitra® device (CE-IVD /IVDR), Biological: Blood sampling for azole antifungal drug dosage (venous puncture) | University Hospital, Caen | Adult Acute Myeloid Leukemia | 02/25 | 01/26 | | |
| MACREZ, Richard |
RIVACAST, NCT06195540: RIVAroxaban Versus Low-molecular Weight Heparin in Patients with Lower Limb Trauma Requiring Brace or CASTing |
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| Recruiting | 3 | 1424 | Europe | Rivaroxaban 10 MG, Low Heparin Molecular Weight | University Hospital, Angers | Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma, Thromboprophylaxis, Immobilisation | 11/26 | 11/26 | | |
PRESTO-F, NCT04121013: PREhospital Routage of Acute STroke Patients With Suspected Large Vessel Occlusion: Mothership Versus Drip and Ship |
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| Recruiting | N/A | 800 | Europe | mothership | University Hospital, Caen | Stroke | 01/22 | 01/22 | | |
NCT04870684: Thromboelastometry and Ischemic Stroke (ThromboPredict) |
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| Not yet recruiting | N/A | 200 | Europe | thromboelastometry test | University Hospital, Caen | Cerebrovascular Stroke, Thrombolytic Therapy, Mechanical Thrombectomy | 04/24 | 05/24 | | |
| Marcelli, Christian |
| Recruiting | 4 | 144 | Europe | Gabapentin 300mg, NEUROTIN, PLACEBO | Lille Catholic University | Radiculopathy of Lumbosacral Spine Due to Disc Disorder | 02/25 | 02/25 | | |
TIM-DYS, NCT06177327: Hepato-pancreato-biliary Abnormalities in Fibrous Dysplasia of Bone/McCune Albright Syndrome |
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| Recruiting | N/A | 545 | Europe | Screening for hepato-bilio-pancreatic abnormalities in Fibrous dysplasia of bone /McCune Albright syndrome , description and characterization of the lesions. | Hospices Civils de Lyon | Fibrous Dysplasia of Bone | 11/24 | 12/25 | | |
| Pizzoferrato, Anne-Cécile |
| Recruiting | N/A | 25 | Europe | Exploratory pathophysiology Study | University Hospital, Caen | Urinary Incontinence, Obesity, Urodynamics, Quality of Life | 01/22 | 01/23 | | |
| Recruiting | N/A | 200 | Europe | Evaluation of laparoscopic promontofixation | University Hospital, Caen | Pelvic Organ Prolapse, Symptoms, Satisfaction, Quality of Life | 06/22 | 10/22 | | |
| Active, not recruiting | N/A | 19000 | Europe | urinary incontinence, pelvic organ or rectal prolapse surgery | Poitiers University Hospital, Agence Nationale de sécurité du Médicament | Pelvic Organ Prolapse, Rectal Prolapse, Urinary Stress Incontinence | 05/33 | 05/33 | | |
| TOUZE, Emmanuel |
PRESTO-F, NCT04121013: PREhospital Routage of Acute STroke Patients With Suspected Large Vessel Occlusion: Mothership Versus Drip and Ship |
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| Recruiting | N/A | 800 | Europe | mothership | University Hospital, Caen | Stroke | 01/22 | 01/22 | | |
| Recruiting | N/A | 4000 | Europe | | Hopital Foch | Stroke, Acute | 12/22 | 12/22 | | |
| Jamard, Estelle |
| Recruiting | N/A | 80 | Europe | perineal ultrasound | University Hospital, Caen | Urinary Incontinence,Stress, Ultrasound, Elastography, Contraction; Pelvic, Urethral Hypermobility | 02/22 | 02/22 | | |
| Recruiting | N/A | 200 | Europe | Evaluation of laparoscopic promontofixation | University Hospital, Caen | Pelvic Organ Prolapse, Symptoms, Satisfaction, Quality of Life | 06/22 | 10/22 | | |
| OLLITRAULT, Pierre |
| Recruiting | N/A | 3000 | Europe, Japan, RoW | Cardiac Resynchronization Therapy (CRT) | Biotronik SE & Co. KG | Heart Failure | 03/26 | 03/26 | | |
NCT04496518: Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) |
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| Active, not recruiting | N/A | 2200 | Europe, US | Intrinsic Antitachycardia Pacing (iATP) Therapy | Medtronic | Ventricular Tachycardia | 01/25 | 01/27 | | |
NCT04489225: Personalized Therapy Study - HFRS (TriageHF) Post Approval Study |
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| Active, not recruiting | N/A | 2200 | Europe, US | Observational | Medtronic | Heart Failure | 01/25 | 01/27 | | |
FALCON, NCT05790707: EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment |
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| Recruiting | N/A | 120 | Europe | Atrial fibrillation ablation + antiarrhythmic drugs, Antiarrhythmic drug | Poitiers University Hospital | Mild Cognitive Impairment, Persistent Atrial Fibrillation | 02/25 | 02/25 | | |
| Recruiting | N/A | 436 | Europe | Ambulatory procedure | Biotronik SE & Co. KG | Heart Failure | 03/26 | 03/26 | | |
ASQ, NCT04024943: Personalized Therapy Study - Attain Stability Quad Post-Approval Study |
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| Active, not recruiting | N/A | 1092 | Europe, US | Quadripolar LV Lead, Medtronic CRT-P, Medtronic CRT-D | Medtronic | Heart Failure | 01/27 | 04/27 | | |
LEANA, NCT06061978: Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation |
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| Recruiting | N/A | 60 | Europe | left bundle branch of His pacing, right ventricular pacing | University Hospital, Rouen | Atrial Fibrillation Rapid | 05/27 | 05/27 | | |
STIMU'HIS, NCT06088927: Long-term Outcomes of Conduction System Pacing: a National Multicenter Observational Study - NORMAND'HIS / |
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| Recruiting | N/A | 2500 | Europe | Conduction system pacing | University Hospital, Rouen | Conduction System Pacing | 03/28 | 03/28 | | |
| Recruiting | N/A | 20 | Europe | | University Hospital, Caen | Myocarditis, Cardiomyopathy | 01/22 | 01/22 | | |
| Recruiting | N/A | 200 | Europe | | University Hospital, Caen | Atrial Fibrillation, Lone Atrial Fibrillation | 01/31 | 01/31 | | |
| BRANGER, Pierre |
TWINS, NCT06663189: Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over ( : Therapies Withdrawal IN Relapsing Multiple Sclerosis) |
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| Not yet recruiting | 3 | 200 | Europe | treatment withdrawal, Usual DMT continuation, MRI, Quality of Life questionnaires, Disability evaluation tests | University Hospital, Strasbourg, France, Ministry of Health, France | Relapsing-remitting Multiple Sclerosis (RRMS) | 01/27 | 06/29 | | |
| Active, not recruiting | 3 | 72 | Europe | Ocrelizumab | Centre Hospitalier Universitaire de Nice | Multiple Sclerosis | 02/26 | 02/29 | | |
MEM-ASA, NCT04368416: Anxiety/Depression, Sleep and Alcohol in Elderly Anxiety/Depression, Sleep Disturbances and Alcohol Use Disorder in Elderly With Cognitive Complaints |
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| Recruiting | N/A | 3000 | Europe | | University Hospital, Caen | Anxiety State, Sleep Disturbance, Alcohol Abuse, Aging, Dementia | 12/24 | 12/24 | | |
| VARNIER, Frederic |
Von2B, NCT05015244: Impact of Von Willebrand Factor-platelet Aggregates in Patients With Type 2B Disease |
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| Recruiting | N/A | 5 | Europe | 3T (Tesla) Magnetic Resonance Imaging (MRI), Series of neuropsychological tests that cover virtually all cognitive domains | University Hospital, Caen | Von Willebrand Disease, Type 2B | 12/23 | 12/23 | | |
| Lefrancois, Valentin |
CoC, NCT06194058: Rapid Sequence Intubation and Hemodynamic Disorders in the Operating Room: a Prospective Multicenter Observational Study |
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| Recruiting | N/A | 1150 | Europe | rapid sequence anesthetic induction | Nantes University Hospital, Société Française d'Anesthésie et de Réanimation | Rapid Sequence Intubation | 11/24 | 05/25 | | |
