The Aurum Institute: Rustenberg
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 2 Trials 
7 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brumskine, William
Sisonke Boost, NCT05148845: Sisonke 2 - A COVID-19 Vaccine Boost Open Label Study.

Recruiting
3b
500000
RoW
Booster vaccine
Wits Health Consortium (Pty) Ltd, National Department of Health of South Africa, National Institute of Communicable Diseases - NICD, KwaZulu-Natal Research Innovation and Sequencing Platform - KRISP, Fred Hutchinson Cancer Center, Hutchinson Center Research Institute of South Africa (HCRISA), Janssen Vaccines & Prevention B.V., Bio Analytical Research Corporation, Dis-Chem Pharmacy, BioVac, Biocair, Right to Care, Clinical Laboratory Services, Institute of Infectious Disease and Molecular Medicine
SARS CoV 2 Infection
01/22
06/23
REVIVE, NCT05580666: Reducing Mortality in Adults With Advanced HIV Disease

Recruiting
3
8000
RoW
Azithromycin Oral Tablet, Placebo oral tablet
Population Health Research Institute
HIV Disease Progression
05/28
08/28
panTB-HM, NCT05686356: A Pan-TB Regimen Targeting Host and Microbe

Recruiting
2/3
352
RoW
Sutezolid, N-acetyl cysteine, NAC, Pretomanid, Bedaquiline, Rifafour
The Aurum Institute NPC, Ludwig-Maximilians - University of Munich, Stichting Katholieke Universiteit, Wits Health Consortium (Pty) Ltd, Instituto Nacional de Saúde, Mozambique, National Institute for Medical Research, Tanzania, University of Stellenbosch, Sequella, Inc., Global Alliance for TB Drug Development
Tuberculosis
09/25
09/25
PaSEM, NCT04179500: A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis

Completed
2
26
RoW
Pretomanid, Pa-824, Doprevla, Pa, Bedaquiline, Sirturo, B, moxifloxacin, Avelox, M, pyrazinamide, Pyzina, Tebrazid, Z
Global Alliance for TB Drug Development
Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR, Tuberculosis, Drug-Resistant Tuberculosis
06/23
07/24
AUR1-8-341, NCT05515042: Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults.

Active, not recruiting
2
694
RoW
Ad26.COV2.S (VAC31518, JNJ-78436735) Vaccine, SARS-CoV-2 rS (CovovaxTM), BNT162b2 (Pfizer)
The Aurum Institute NPC, Coalition for Epidemic Preparedness Innovations
COVID-19
06/24
12/24
NCT06058299: Phase 2 Trial Assessing TBAJ876 or Bedaquiline, with Pretomanid and Linezolid in Adults with Drug-sensitive Pulmonary Tuberculosis

Active, not recruiting
2
309
RoW
TBAJ-876, Pretomanid, PA-824, Dovprela, Linezolid, Zyvox, Bedaquiline, Sirturo, TMC207, HRZE, HR
Global Alliance for TB Drug Development
Pulmonary TB, Pulmonary Tuberculosis, Drug Sensitive Tuberculosis
01/25
06/26
PAUSE, NCT06031272: Pausing Antiretroviral Treatment Under Structured Evaluation

Recruiting
1
48
RoW
3BNC117-LS-J, 10-1074-LS-J, Placebo for 3BNC117-LS-J, Placebo for 10-1074-LS-J
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, National Institute of Allergy and Infectious Diseases (NIAID)
HIV-1-infection
06/25
06/26

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