Wroclaw Medical University Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Jankowska, Ewa A

FAIR-HF2, NCT03036462 / 2016-000068-40: Intravenous Iron in Patients with Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality

Completed

1105

Europe

Iron, Saline, salin

Universitätsklinikum Hamburg-Eppendorf, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Charite University, Berlin, Germany

Systolic Heart Failure, Iron Deficiency

05/24

COG01, NCT06313840: Central Sleep Apnea Prevalence and Impact on Cognitive Function in Patients With Heart Failure With Reduced or Mildly Reduced Left Ventricular Ejection Fraction

Recruiting

N/A

200

Europe

Zoll Medical Corporation

Heart Failure, Central Sleep Apnea

09/24

11/24

Tabakow, Pawel

NCT03933072: Autologous Bulbar Olfactory Ensheathing Cells and Nerve Grafts for Treatment of Patients With Spinal Cord Transection

Recruiting

1/2

Europe

obtaining of autologous human olfactory bulb, autologous sural nerve preparation, production of Glial Neuropatch, microsurgical reconstruction of the transected spinal cord with autologous Glial Neuropatch-nerve bridges

Nicholls Spinal Injury Foundation, Wroclaw Medical University, Akson, Neuro-Rehabilitation Center for the Treatment of Spinal Cord Injuries, University College, London, Poznan University of Medical Sciences

Spinal Cord Injury at C5-Th10 Level With Complete Lesion, Spinal Cord Transection

03/23

Locatelli, Franco

NCT02670564: ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)

Recruiting

1000

Europe

Pharmacogenomics, DNA analyses, Busulfan plasma level measurements

Swiss Pediatric Oncology Group, ALL SCTped Forum

Acute Lymphoblastic Leukemia

04/21

04/26

ALLELE, NCT03394365 / 2017-002949-30: Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants with Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy

	Data from ALLELE trial for post-transplant lymphoproliferative disease
	Dec 2021 - Dec 2021: Data from ALLELE trial for post-transplant lymphoproliferative disease

Recruiting

Europe, Canada, US, RoW

tabelecleucel, tab-cel®, ATA129, EBV-CTL

Atara Biotherapeutics

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications

08/25

06/27

NCT01728155: European Low and Intermediate Risk Neuroblastoma Protocol

Completed

685

Europe, RoW

chemotherapy

Instituto de Investigacion Sanitaria La Fe

LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES

12/22

TRACE, NCT04832607 / 2018-000853-29: Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections

Recruiting

149

Europe

Multivirus (CMV, EBV, AdV)-specific T cells

Prof. Tobias Feuchtinger, European Commission, Simbec-Orion Group Ltd, Merthyr Tydfil, UK, Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany, Leiden University Medical Center, LUMC, Leiden, The Netherlands, Centre Hospitalier Universitaire de Nancy, CHU, Vandoeuvre-Lès-Nancy, France, Ghent University Hospital, UZG, Ghent, Belgium, Ospedale Pediatrico Bambino Gesù, OPBG, Rome, Italy, Newcastle University, UNEW, Newcastle, UK, Vall d'Hebron Institute of Oncology (VHIO) and Banc de Sang I Teixits (BST), Barcelona, Spain

AdV Infection, EBV Infection, CMV Infection, Stem Cell Transplant Complications

06/24

12/24

AIEOP-BFM ALL 2017, NCT03643276 / 2016-001935-12: Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia -

Recruiting

5000

Europe, RoW

Blinatumomab, Bortezomib, Cyclophosphamide, Cytarabine, Daunorubicin, Myocet, Dexamethasone, Doxorubicin, Etoposide, Fludarabine Phosphate, Ifosfamide, 6-Mercaptopurine, Methotrexate, Pegaspargase, Prednisolone, Prednisone, Tioguanin, Vincristine, Vindesine, Erwinase

Martin Schrappe, Deutsche Krebshilfe e.V., Bonn (Germany)

Acute Lymphoblastic Leukemia, Pediatric

07/28

FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting

2/3

1800

Europe, Canada, RoW

VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin

St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group

Acute Lymphoblastic Leukaemia

06/25

04/30

NCT04785547: ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT

Terminated

Europe, RoW

Blinatumomab, Blincyto

Prof. Christina Peters, Amgen

ALL, Childhood, Minimal Residual Disease

01/22

NCT04793919 / 2017-002383-40: Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Recruiting

Europe, RoW

Mylotarg, GO, Arsenic Trioxide, ATO, All-trans retinoic acid, ATRA

Associazione Italiana Ematologia Oncologia Pediatrica, AIEOP

Acute Promyelocytic Leukemia

10/25

10/27

XCGD-MOBI, NCT03055247 / 2015-002356-27: Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD

Recruiting

Europe

Ibuprofen, Myelostim, Mozobil

IRCCS San Raffaele, Fondazione Telethon

Chronic Granulomatous Disease X-linked (X-CGD)

07/23

NCT03590171: International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Recruiting

250

Europe, RoW

Bortezomib

Charite University, Berlin, Germany, Australian & New Zealand Children's Haematology/Oncology Group, St. Anna Kinderkrebsforschung, CCRI (co-sponsor, Austria), European Organisation for Research and Treatment of Cancer - EORTC, University Hospital Motol (Co-Sponsor Czech Republic), Copenhagen University Hospital, Rigshospitalet (co-sponsor, Denmark), Turku University Central Hospital (co-sponsor, Finland), Centre Hospitalier Universitaire de Nice, Our Lady's Chilrden's Hospital (Co-Sponsor Ireland), Tel Aviv Sourasky Medical Centre (Co-Sponsor Israel), Ospedale Pediatrico Bambino (co-sponsor, Italy), Prinses Máxima Centrum (Co-Sponsor Netherlands), Oslo University Hospital (co-sponsor, Norway), Medical University of Wroclaw (Co-Sponsor Poland), Instituto Português de Oncologia de Lisboa (co-sponsor, Portugal), Karolinska University Hospital Stockholm (co-sponsor, Sweden), Spanish Society of Pediatric Hematology and Oncology (SEHOP) (Co-Sponsor Spain), University Children's Hospital, Zurich, Central Manchester University Hospitals NHS Foundation Trust (co-sponsor, UK)

Acute Lymphoblastic Leukemia (ALL)

12/27

EBVision, NCT04554914 / 2020-000177-25: A Study to Evaluate Tabelecleucel in Participants with Epstein-barr Virus-associated Diseases

Jan 2023 - Dec 2023 : From P2 trial for Epstein-Barr virus-associated sarcoma

Recruiting

190

Europe, US

Tabelecleucel, tab-cel®, ATA129, EBV-CTLs

Atara Biotherapeutics

Epstein-Barr Virus (EBV)-associated Diseases, EBV+ Lymphoproliferative Disease with Primary Immunodeficiency (EBV+ PID LPD), EBV+ Lymphoproliferative Disease with Acquired (non-congenital) Immunodeficiency (EBV+ AID LPD), EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous System (EBV+ CNS PTLD), EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications, EBV+ Sarcomas, Leiomyosarcoma

06/27

05/29

NCT03373097 / 2017-002475-26: Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors

Recruiting

1/2

Europe

GD2-CART01

Bambino Gesù Hospital and Research Institute

Neuroblastoma, Neuroblastoma Recurrent, GD2-positive Solid Tumors, Osteosarcoma, Ewing Sarcoma, Sarcoma

12/24

12/27

NCT04501614 / 2019-002549-39: A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Terminated

1/2

Europe, US, RoW

Ponatinib, Chemotherapy Agents

Takeda, Takeda Development Center Americas, Inc.

Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)

12/23

07/24

NCT06521567: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Recruiting

1/2

Cobolimab, Dostarlimab

GlaxoSmithKline

Melanoma

08/28

11/30

NCT04787263: CD19-CAR_Lenti T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and DLBCL or PML

Recruiting

1/2

Europe

CD19-CAR_Lenti T cell

Bambino Gesù Hospital and Research Institute

Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Primary Mediastinal Lymphoma

03/25

03/38

CD7-CAR01, NCT06064903: CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL

Recruiting

1/2

Europe

CD7-CART01

Bambino Gesù Hospital and Research Institute

T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

09/28

09/40

HEM-iSMART D, NCT05658640: HEM ISMART-D: Trametinib + Dexamethasone + Chemotherapy in Children with Relapsed or Refractory Hematological Malignancies

Recruiting

1/2

Europe, RoW

Trametinib, Dexamethasone, Cyclophosphamide, Cytarabine, Intrathecal chemotherapy

Princess Maxima Center for Pediatric Oncology, Innovative Therapies For Children with Cancer Consortium, IBFM, Fight Kids Cancer

Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

04/29

NCT06080191: Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

Recruiting

Europe

CD19-CAR_Lenti_ALLO

Bambino Gesù Hospital and Research Institute

B-cell Acute Lymphoblastic Leukemia

06/26

06/41

NCT05298995: GD2-CAR T Cells for Pediatric Brain Tumours

Recruiting

Europe

GD2-CART01 (iC9-GD2-CAR T-cells)

Bambino Gesù Hospital and Research Institute

Brain Tumor, Pediatric, Medulloblastoma, Childhood, Embryonal Tumor, High Grade Glioma, Diffuse Midline Glioma, Diffuse Intrinsic Pontine Glioma, Brain Tumor Adult

11/27

11/38

RAG1-SCID, NCT04797260: Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID

Recruiting

N/A

Europe, RoW

Gene therapy

Leiden University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Horizon 2020 - European Commission

Severe Combined Immunodeficiency Due to RAG1 Deficiency

12/29

HEMOGLOB-VAX, NCT05157256: Monitoring of Anti-SARS-CoV-2 (COVID 19) and Encapsulated Vaccination Patients With Thalassemic and Falcemic Syndromes

Active, not recruiting

N/A

1000

Europe

Società Italiana Talassemie ed Emoglobinopatie

SARS-CoV-2 Infection, Thalasemmie, SCD

12/30

Neubauer, Katarzyna

NCT06275204: H. Pylori Screen-and-treat Study in a Population of Young Adults

Recruiting

N/A

6800

Europe, RoW

Bismuth-based quadruple therapy, Levofloxacin-based quadruple therapy, Standard triple therapy, Levofloxacin-based triple

University of Latvia, Clinical Hospital Center Rijeka, Clinical Hospital Centre Zagreb, Beacon Hospital, Wroclaw Medical University, Iuliu Hatieganu University of Medicine and Pharmacy, National Institute of Public Health, Slovenia

Gastric Cancer, H Pylori Infection, H Pylori Eradication, H-pylori

10/26

12/26

Mazurek, Justyna

NCT06002139: Virtual Reality in Orthopedic Rehabilitation

Completed

N/A

Europe

Immersive Virtual Reality Therapy, Conventional rehabilitation

Joanna Szczepańska-Gieracha, Wroclaw Medical University, Wroclaw University of Health and Sport Sciences, Jan Dlugosz University in Czestochowa

Arthropathy, Anxiety, Stress

09/23

10/23

NCT06506760: Immersive VR for Female Orthopaedic Rehabilitation

Active, not recruiting

N/A

Europe

Immersive Virtual Reality Therapy, Conventional rehabilitation

Wroclaw University of Health and Sport Sciences, Wroclaw Medical University, Jan Dlugosz University in Czestochowa

Hip Arthropathy

08/24

Moskal, Åukasz

NCT05488743: Smoking Prevention Program in Poland

Active, not recruiting

N/A

180

Europe

educational intervention

Wroclaw Medical University, Stanford Reach Lab - Tobacco Prevention Toolkit, American Association for Cancer Education

Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use, Vaping

08/22

10/22

Reszka, Konrad

NCT05488743: Smoking Prevention Program in Poland

Active, not recruiting

N/A

180

Europe

educational intervention

Wroclaw Medical University, Stanford Reach Lab - Tobacco Prevention Toolkit, American Association for Cancer Education

Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use, Vaping

08/22

10/22

Staszek-Szewczyk, Urszula

NCT05488743: Smoking Prevention Program in Poland

Active, not recruiting

N/A

180

Europe

educational intervention

Wroclaw Medical University, Stanford Reach Lab - Tobacco Prevention Toolkit, American Association for Cancer Education

Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use, Vaping

08/22

10/22

Åaba, Jagoda

NCT05488743: Smoking Prevention Program in Poland

Active, not recruiting

N/A

180

Europe

educational intervention

Wroclaw Medical University, Stanford Reach Lab - Tobacco Prevention Toolkit, American Association for Cancer Education

Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use, Vaping

08/22

10/22

Szewczyk, Krzysztof

NCT05488743: Smoking Prevention Program in Poland

Active, not recruiting

N/A

180

Europe

educational intervention

Wroclaw Medical University, Stanford Reach Lab - Tobacco Prevention Toolkit, American Association for Cancer Education

Smoking, Smoking Behaviors, Smoking (Tobacco) Addiction, E-cigarette Use, Vaping

08/22

10/22

Biegus, Jan

NCT06725927: Vaccination Against Influenza Pre-discharge in Heart Failure

Not yet recruiting

200

Influenza vaccination

Wroclaw Medical University

Heart Failure

11/25

12/25

SOLVRED-AHF, NCT05962255: Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure

Completed

Europe

Furosemide intravenous infusion, Continous intravenous infusion of 0.9% Sodium Chloride solution, Continous intravenous infusion of 5% Glucose solution

Wroclaw Medical University

Acute Heart Failure, Congestion, Heart Failure

04/24

VACCINE-CHF, NCT06259487: Coordinated Vaccination Against RSV and Influenza in Patients With Chronic Heart Failure and Its Impact on Prognosis.

Recruiting

N/A

250

Europe

Coordinated Vaccination, Following recommendations

Wroclaw Medical University

Heart Failure, RSV Infection, Influenza, Vaccines

06/24

07/24

FASTR-EU, NCT06362668: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System

Recruiting

N/A

Europe

Reprieve Decongestion Management System, Diuretic (furosemide, bumetanide, torsemide, hydrochlorothiazide, and/or acetazolamide)

Reprieve Cardiovascular, Inc

Acute Decompensated Heart Failure

10/24

12/24

DELTA-HF, NCT05747196: The Safety and Feasibility of the eLym™ System

Recruiting

N/A

Europe, RoW

WhiteSwell eLym System

WhiteSwell, Limited

Heart; Decompensation, Congestive

06/25

12/25

Bradic, Tihomir

NCT06275204: H. Pylori Screen-and-treat Study in a Population of Young Adults

Recruiting

N/A

6800

Europe, RoW

Bismuth-based quadruple therapy, Levofloxacin-based quadruple therapy, Standard triple therapy, Levofloxacin-based triple

Gastric Cancer, H Pylori Infection, H Pylori Eradication, H-pylori

10/26

12/26



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