Zhang, Yan |
NCT05291650: Ultrasound-guided Injection of Glucocorticoid Into Infrapatellar Fat Pad in Patients With Knee Osteoarthritis |
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| Completed | 4 | 60 | RoW | Glucocorticoids, Saline, Hyaluronic acid | Zhujiang Hospital | Osteoarthritis, Knee | 09/23 | 12/23 | | |
NCT04790305: Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer |
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| Recruiting | 4 | 1072 | RoW | Huaier Granule, Z20000109(NMPA Approval Number) | Fudan University, LinkDoc Technology (Beijing) Co. Ltd., Huazhong University of Science and Technology | Carcinoma Breast, Triple-negative Breast Cancer, Invasive Ductal Carcinoma, Breast | 12/27 | 07/28 | | |
ETER701, NCT04234607: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer |
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| Not yet recruiting | 3 | 738 | RoW | TQB2450, Anlotinib, Etoposide, Carboplatin, TQB2450(blank), Anlotinib(blank) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Extensive Small Cell Lung Cancer | 12/22 | 12/22 | | |
| Active, not recruiting | 3 | 453 | Europe, US, RoW | MRTX849, adagrasib, KRAZATI, Docetaxel, Taxotere | Mirati Therapeutics Inc., Mirati Therapeutics, Inc. | Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer | 12/23 | 12/24 | | |
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NCT05181137 / 2021-001940-86: A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis |
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| Recruiting | 3 | 368 | Europe, US, RoW | SHR0302, Placebo | Reistone Biopharma Company Limited, Reistone Biopharma Company Limited | Ulcerative Colitis | 10/24 | 03/25 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
NCT02159820: Lower Dose Decitabine (DAC)-Primed TC (Carboplatin-Paclitaxel) Regimen in Ovary Cancer |
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| Recruiting | 2/3 | 500 | RoW | Decitabine (DTC Arm), Paclitaxel and Carboplatin (TC Arm) | Chinese PLA General Hospital | Primary Malignant Neoplasm of Ovary, FIGO Stages II to IV | 06/24 | 06/24 | | |
EVEREST, NCT06531161: EleVation carE: a Randomized Controlled Trial on the Prevention of Acute Mountain Sickness With Suxiao Jiuxin Pill |
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| Not yet recruiting | 2/3 | 168 | NA | Suxiao Jiuxin Pill, Placebo | Peking University First Hospital, Tibet Autonomous Region Hospital of Traditional Tibetan Medicine | Acute Mountain Sickness | 09/24 | 09/25 | | |
NCT03989336: A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer |
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| Completed | 2 | 84 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Platinum chemotherapy, Sintilimab, anti-PD-1 antibody; PD-1 inhibitor | Chinese PLA General Hospital | Ovarian Cancer | 05/22 | 12/23 | | |
NCT03250962: SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma |
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| Recruiting | 2 | 280 | RoW | SHR-1210, Decitabine | Chinese PLA General Hospital | Hodgkin Lymphoma | 07/22 | 03/25 | | |
LEAD, NCT05092412: Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC |
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| Active, not recruiting | 2 | 30 | RoW | Low-dose radiotherapy, Durvalumab, Etoposide, and cisplatin/carboplatin | You Lu, AstraZeneca | Lung Cancer, Extensive-stage Small-cell Lung Cancer, Durvalumab | 02/23 | 06/25 | | |
| Recruiting | 2 | 30 | RoW | Polatuzumab Vedotin, Rituximab, Lenalidomide | Yan Zhang, MD, Peking University Third Hospital, Peking University First Hospital, Chinese PLA General Hospital | Diffuse Large B Cell Lymphoma | 10/25 | 10/27 | | |
PUMCH-NHL-013, NCT05390749: Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL |
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| Recruiting | 2 | 50 | RoW | Orelabrutinib, Pomalidomide, Rituximab, Methotrexate | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Sanbo Brain Hospital Capital Medical University | Primary Central Nervous System Lymphoma | 04/24 | 04/26 | | |
NCT06632262: A Phase 2 Clinical Study of ABSK061 and ABSK043 |
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| Not yet recruiting | 2 | 202 | RoW | ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX | Abbisko Therapeutics Co, Ltd | HER2-Gastric/Gastroesophageal Junction Cancer, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Solid Tumors | 11/29 | 06/30 | | |
FOCUS-C, NCT05334277: Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA |
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| Recruiting | 2 | 280 | RoW | Furmonertinib, AST2818, Furmonertinib/Pemetrexed/Carboplatin, Furmonertinib/Pemetrexed/Carboplatin/Bevacizumab | Sun Yat-sen University, Allist Pharmaceuticals, Inc., GeneCast Biotechnology Co., Ltd. | Non-small Cell Lung Cancer | 02/25 | 02/28 | | |
IMM01-04, NCT05833984: Safety and Efficacy of IMM01 Plus Tislelizumab in Patients With Advanced Solid Tumors and Lymphomas |
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| Recruiting | 1b/2 | 309 | RoW | IMM01, SIRPα Fc, Tislelizumab | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | Solid Tumor, Classic Hodgkin Lymphoma | 02/24 | 11/24 | | |
NCT03989310: An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 1/2 | 50 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Gemcitabine, anti-PD-1 antibody, Anti-PD-1 monoclonal antibody; PD-1 inhibitor | Chinese PLA General Hospital | Pancreatic Cancer | 05/21 | 03/22 | | |
NCT04588324: Study of SHR2150 (TLR7 Agonist) in Combination With Chemotherapy Plus PD-1 or CD47 Antibody in Subjects With Unresectable/ Metastatic Solid Tumors |
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| Recruiting | 1/2 | 50 | RoW | SHR2150, Anti-Cancer Agent | Chinese PLA General Hospital | Solid Tumor | 11/21 | 11/22 | | |
NCT04873440: An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma |
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| Recruiting | 1/2 | 10 | RoW | Manganese Chloride, Mn2+, Radiotherapy, Chemo-immunotherapy | Chinese PLA General Hospital | Solid Tumor, Lymphoma | 05/22 | 05/23 | | |
REMLA, NCT04120350: R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL:a Multicenter Phase Ib/II Stuty |
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| Recruiting | 1/2 | 47 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Xuanwu Hospital, Beijing, Peking University Third Hospital, Beijing Hospital, Peking University First Hospital, Chinese PLA General Hospital | Primary Central Nervous System Lymphoma | 08/22 | 08/24 | | |
NCT05867771: A Study of PM1022 in Patients With Advanced Tumors |
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| Recruiting | 1/2 | 200 | RoW | PM1022 | Biotheus Inc. | Advanced Tumors | 04/24 | 04/25 | | |
NCT05416775: Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer |
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| Recruiting | 1/2 | 168 | RoW | SHR-8068;Adebrelimab, SHR-8068;adebrelimab and platinum-based chemotherapy, Adebrelimab;platinum-based chemotherapy | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Non-small Cell Lung Cancer | 06/26 | 06/26 | | |
NCT05245916: IBI397 or Combination Therapies in Patients With Advanced Malignancies |
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| Withdrawn | 1a/1b | 30 | RoW | IBI397, IBI397+Sintilimab, IBI397+Rituximab | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Malignancies | 08/23 | 08/23 | | |
NCT06271928: A Multicenter Clinical Study of Yijing Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Yijing Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
NCT04487093: Clinical Study of Neoantigen Vaccine Combined With Targeted Drugs in the Treatment of Non-small Cell Lung Cancer |
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| Recruiting | 1 | 20 | RoW | neoantigen vaccine + EGFR-TKI, neoantigen vaccine + anti-angioge | First Hospital of Shijiazhuang City, Tianjin Hengjia Biotechnology Development co., LTD | Non Small Cell Lung Cancer | 05/22 | 12/22 | | |
NCT06256783: A Clinical Study of Baozhu Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Baozhu Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
| Recruiting | 1 | 132 | Japan, RoW | SHR-A2009 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Solid Tumors | 12/23 | 12/24 | | |
NCT05508334: A Study to Assess the Safety and Tolerability of RC88 for Patients with Advanced Solid Tumours |
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| Active, not recruiting | 1 | 81 | RoW | RC88, The injectable RC88 | RemeGen Co., Ltd. | Advanced Solid Tumours | 06/25 | 12/25 | | |
| Recruiting | 1 | 156 | US, RoW | CS5001 | CStone Pharmaceuticals | Advanced Solid Tumor, Advanced Lymphoma | 03/25 | 06/25 | | |
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NCT06384352: A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 155 | Canada, US, RoW | YL211 | MediLink Therapeutics (Suzhou) Co., Ltd., Hoffmann-La Roche | Advanced Solid Tumors | 04/27 | 04/29 | | |
| Completed | N/A | 70 | RoW | Plasma exchange (PE), intravenous immunmoglobulin (IVIG), intravenous methylprednisolone (IVMP) | Xuanwu Hospital, Beijing | Autoimmune Encephalitis | 12/22 | 09/24 | | |
NCT03703284: Molecular Mechanisms of Malignant Cerebral Edema After LHI |
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| Recruiting | N/A | 120 | RoW | Treatments to reduce intracranial pressure | Xuanwu Hospital, Beijing | Cerebral Edema | 12/22 | 06/23 | | |
UltraFuture I, NCT05498740: Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia |
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| Recruiting | N/A | 200 | RoW | Drug eluting Balloon | Zhejiang Zylox Medical Device Co., Ltd. | Peripheral Arterial Disease (PAD) | 12/22 | 12/24 | | |
NCT05447572: FIT Combining FC for Predicting MH and Histology Remission in UC |
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| Recruiting | N/A | 300 | RoW | FIT + FC | Shandong University | Ulcerative Colitis, Histology Remission, Fecal Calprotetin, FIT, Mucosal Healing | 12/22 | 12/23 | | |
NCT04361357: The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients |
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| Recruiting | N/A | 116 | RoW | whey protein | Xuanwu Hospital, Beijing | Nutrition Disorders, Neurologic Disorder | 12/22 | 12/22 | | |
NCT05840861: Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders |
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| Recruiting | N/A | 59 | RoW | Vortioxetine, Quetiapine | Central South University | Major Depressive Disorder, Bipolar Disorder | 08/23 | 09/23 | | |
DELTA, NCT05608655: DKutting Balloon Versus Chocolate Balloon to Treat Femoral and Popliteal Artery Stenosis |
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| Completed | N/A | 188 | RoW | DKutting LL balloon, Chocolate balloon | DK Medical Technology (Suzhou) Co., Ltd. | Femoral Artery Stenosis, Popliteal Artery Stenosis | 01/24 | 02/24 | | |
BIATICH, NCT05593380: The Effect of BIA Monitoring of Brain Edema on the Neurological Prognosis of Supratentorial Massive ICH |
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| Recruiting | N/A | 190 | RoW | Parenchymal Intracranial pressure monitor, Integra Life Sciences Camino Intracranial Monitor, Treatment based on clinical and imaging observations | Xiangya Hospital of Central South University | Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension, Monitoring, Critical Care, Treatment Outcome, Invasive Intracranial Pressure Monitoring, Large-volume Cerebral Hemorrhage | 12/24 | 03/25 | | |
NCT06130319: Correlation of Disease Management and Quality of Life in Patients With Chronic Heart Failure and Their Family Caregivers |
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| Recruiting | N/A | 278 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Chronic Heart Failure | 06/24 | 06/24 | | |
| Not yet recruiting | N/A | 768 | RoW | early pancreatic stent placement (EPSP), late pancreatic stent placement (EPSP) | The First Affiliated Hospital of Anhui Medical University, First Affiliated Hospital Bengbu Medical College, Anqing Municipal Hospital, First Affiliated Hospital of Wannan Medical College, Tongcheng People's Hospital of Anhui province, Fuyang people's hospital | Cholangiopancreatography, Endoscopic Rretrograde, Post-ERCP Pancreatitis | 03/26 | 03/26 | | |
NCT06452173: Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis |
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| Enrolling by invitation | N/A | 300 | RoW | Plasma, carotid high-resolution magnetic resonance imaging | Beijing Tiantan Hospital, Beijing Neurosurgical Institute | Carotid Stenosis | 10/26 | 12/26 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT05454397: A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients |
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| Recruiting | N/A | 2000 | RoW | Observational study, no intervention | Nanfang Hospital of Southern Medical University, First Affiliated Hospital of Fujian Medical University, Yantai Yuhuangding Hospital, The First Hospital of Jilin University, Qilu Hospital of Shandong University, ZHEJIANG PROVINCE XIAOSHAN HOSPITAL, The First People's Hospital of Wenling, Ganzhou People's Hospital, Affiliated Hospital of Jining Medical hospital, Henan Provincial People's Hospital, Zhongda Hospital Southeast University, The Second Affiliated Hospital of Harbin Medical University, The First people's Hospital of Kunshan, The 2nd Affiliated Hospital of Wenzhou Medical University, THE FIRST PEOPLE'S HOSPITAL OF JIASHAN, The First Affiliated Hospital of Xi'an Jiaotong University Medical College, Fujian Province Zhangzhou Hospital, People's Hospital of Chongqing, Nanjing Zijin Hospital, Hangzhou Red Cross Hospital, Wenzhou Hospital of Chinese Medicine, Kaifeng Central Hospital, First Affiliated Hospital of Guangxi Medical University, Zhongshan Hospital of Xiamen University, Xi'an Encephalopathy of Traditional Chinese Medicine Hospital, 903 Hospital of the Chinese People's Liberation Army Joint Logistics and Security Forces, Xiangya Hospital of Central South University, Second Affiliated Hospital of Suzhou University, Tongji Hospital, The Affiliated Hospital o fQingdao University, The First Affiliated Hospital of Anhui Medical University, Yancheng Third People's Hospital, Linyi People's Hospital, Dongfang Hospital of Beijing University of Chinese Medicine, Affiliated Hospital of Qingdao University | Acute Stroke | 10/22 | 10/23 | | |
Ding, Changhai |
GNC-035-103, NCT05160545: A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Breast Cancer |
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| Recruiting | 1 | 29 | RoW | GNC-035 | Sichuan Baili Pharmaceutical Co., Ltd., Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. | Breast Cancer | 06/25 | 12/25 | | |
NCT05339685: A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors |
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| Recruiting | 1 | 26 | RoW | BL-M02D1 | Sichuan Baili Pharmaceutical Co., Ltd., SystImmune Inc., Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. | Breast Cancer | 12/24 | 12/24 | | |
IPAKA, NCT03763448: Infrapatellar Fat Pad Preservation Versus Resection on Clinical Outcomes After Total Knee Arthroplasty |
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| Recruiting | N/A | 360 | RoW | Infrapatellar Fat Pad preservation, Infrapatellar fat pad retention, Infrapatellar Fat Pad resection | Zhujiang Hospital, Peking Union Medical College Hospital, Peking University People's Hospital, Xiangya Hospital of Central South University, The First Affiliated Hospital of Anhui Medical University, First Affiliated Hospital of Jinan University, Anhui Provincial Hospital, Tianjin Hospital, Affiliated Hospital of Youjiang Medical University for Nationalities | Knee Osteoarthritis, Arthropathy of Knee | 12/22 | 12/23 | | |
NCT03815448: Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis |
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| Completed | N/A | 215 | RoW | Methotrexate, MTX, Placebo | Zhujiang Hospital, Peking Union Medical College Hospital, Third Affiliated Hospital, Sun Yat-Sen University, Beijing Hospital, Xuanwu Hospital, Beijing, The First Affiliated Hospital of Anhui Medical University, The Second People's Hospital of GuangDong Province, Peking University People's Hospital, Shenzhen Third People's Hospital, Central People's Hospital of Zhanjiang, Qingyuan City People's Hospital | Knee Osteoarthritis, Effusion Synovial, Knee Pain | 11/23 | 12/23 | | |
Liu, Jun |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT03432637: Clinical Trial of Thoracoscopic Lobecotmy Under Spontaneous Ventilating Anesthesia |
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| Recruiting | 3 | 450 | RoW | spontaneous ventilation, intubated anesthesia with single-lung mechanical ventilation | Guangzhou Institute of Respiratory Disease, Shenzhen People's Hospital, Tongji Hospital | Non Small Cell Lung Cancer | 03/19 | 03/24 | | |
NCT05092841: A Study to Assess the Efficacy and Safety of PXT3003 in Charcot-Marie-Tooth Type 1A |
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| Completed | 3 | 176 | RoW | PXT3003, (RS)-baclofen, naltrexone hydrochloride and D-sorbitol oral fixed dose combination, PXT3003 placebo, liquid oral solution | Tasly GeneNet Pharmaceuticals Co., Ltd | Charcot-Marie-Tooth Type 1A | 03/24 | 03/24 | | |
NCT05862337: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence. |
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| Recruiting | 3 | 480 | RoW | Anlotinib hydrochloride capsules, Penpulimab injection, Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Hepatocellular Carcinoma | 08/24 | 12/26 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT02820116: The Role of Icotinib in the Perioperative Treatment of IIIA - IIIB NSCLC Patients With EGFR Mutation |
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| Recruiting | 2 | 67 | RoW | Icotinib, Conmana | Beijing Haidian Hospital, Peking University People's Hospital, 307 Hospital of PLA, 309th Hospital of Chinese People's Liberation Army | Non-small Cell Lung Cancer(NSCLC) | 04/23 | 04/23 | | |
NCT04391361: The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS |
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| Not yet recruiting | 2 | 30 | RoW | Scopolamine, atropine, edaravone and dexmedetomidine, Edaravone | Ruijin Hospital | Amyotrophic Lateral Sclerosis, Respiratory Function, Scopolamine | 09/23 | 10/23 | | |
NCT05650216: Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC(NICE-RT) |
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| Not yet recruiting | 2 | 50 | RoW | Chemotherapy (nab-paclitaxel AUC=2 and carboplatin 80mg/m2),Immunotherapy (camrelizumab 200mg)、Radiotherapy(primary lesion and adjacent lymph nodes 41.4Gy, distant lymph node 0.5Gy*4), Camrelizumab: ai rui ka, SHR-1210; Nab-paclitaxel: ai yue | Shanghai Chest Hospital | Esophageal Squamous Cell Carcinoma | 12/23 | 12/24 | | |
NCT06709417: A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS) |
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| Recruiting | 2 | 52 | RoW | Sintilimab, Chemotherapy, radiotherapy | Shanghai Chest Hospital | Esophageal Squamous Cell Carcinoma (ESCC) | 12/27 | 12/28 | | |
NCT05527808: A Single-arm Exploratory Study of Neoadjuvant Therapy |
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| Recruiting | 2 | 28 | RoW | Tislelizumab, pemetrexed, cis-platemum, or carboplatin | Jun Liu | Lung Adenocarcinoma | 06/25 | 12/25 | | |
NTNC, NCT03964753: Neoadjuvant Therapy With Nab-paclitaxel and Cisplatin for Locally Advanced Esophageal Squamous Cell Carcinoma |
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| Recruiting | 2 | 202 | RoW | Nab-paclitaxel and Cisplatin, surgery | Hebei Medical University Fourth Hospital | Esophageal Squamous Cell Carcinoma | 06/26 | 12/26 | | |
NCT04534023: A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies |
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| Recruiting | 2 | 142 | RoW | Idebenone, Placebo | Ruijin Hospital, Second Affiliated Hospital of Soochow University, Wuhan Union Hospital, China | Rapid Eye Movement Sleep Behavior Disorder, Synucleinopathy | 09/26 | 09/26 | | |
NCT05241028: Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer |
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| Recruiting | 2 | 80 | RoW | Ensartinib, X-396 capsule | Hebei Medical University Fourth Hospital | Non-small Cell Lung Cancer | 02/27 | 02/29 | | |
NCT06778265: An Exploratory Clinical Study of UX-DA001 in Subjects with Idiopathic Parkinson's Disease |
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| Not yet recruiting | 1 | 12 | RoW | UX-DA001 | Shanghai UniXell Biotechnology Co., Ltd, Ruijin Hospital | Parkinson Disease, Idiopathic | 12/27 | 12/27 | | |
NCT06154811: Exploring the Use of Pulse Tissue Doppler in Predicting Extubation Success in Mechanically Ventilated Patients |
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| Recruiting | N/A | 200 | RoW | | Affiliated Hospital of Jiangnan University | Airway Extubation | 12/24 | 12/24 | | |
IPAKA, NCT03763448: Infrapatellar Fat Pad Preservation Versus Resection on Clinical Outcomes After Total Knee Arthroplasty |
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| Recruiting | N/A | 360 | RoW | Infrapatellar Fat Pad preservation, Infrapatellar fat pad retention, Infrapatellar Fat Pad resection | Zhujiang Hospital, Peking Union Medical College Hospital, Peking University People's Hospital, Xiangya Hospital of Central South University, The First Affiliated Hospital of Anhui Medical University, First Affiliated Hospital of Jinan University, Anhui Provincial Hospital, Tianjin Hospital, Affiliated Hospital of Youjiang Medical University for Nationalities | Knee Osteoarthritis, Arthropathy of Knee | 12/22 | 12/23 | | |
NCT05190861: Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis |
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| Recruiting | N/A | 2000 | RoW | droplet digital PCR method, blood culture | Huashan Hospital | Sepsis, Septic Shock | 12/22 | 06/23 | | |
NCT03748563: Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of EGV in Patients With Cirrhosis |
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| Completed | N/A | 607 | RoW | ds-MCE and EGD | Changhai Hospital, Ruijin Hospital, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai East Hospital of Tongji University, Yangpu District Central Hospital Affiliated to Tongji University, Zhujiang Hospital, Qilu Hospital of Shandong University, The Third Xiangya Hospital of Central South University, First Affiliated Hospital Xi'an Jiaotong University, Wuhan Union Hospital, China, The Fifth Affiliated Hospital of Zunyi Medical College, The First Affiliated Hospital of Zhejiang Chinese Medical University, Shanghai Pudong New Area Gongli Hospital | Liver Cirrhosis, Portal Hypertension, Esophageal Varices, Gastric Varix | 01/23 | 03/23 | | |
NCT05171205: Spinal Cord Stimulation for Multiple System Atrophy |
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| Recruiting | N/A | 50 | RoW | Spinal cord stimulation | Ruijin Hospital | Multiple System Atrophy | 04/25 | 04/25 | | |
| Recruiting | N/A | 60 | RoW | Neuromodulation | Ruijin Hospital | Neuromodulation, Parkinsonian Syndromes, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation | 05/25 | 06/25 | | |
NCT05143593: Species-specific Bacterial Detector for Fast Pathogen Diagnosis of Severe Pneumonia |
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| Not yet recruiting | N/A | 256 | RoW | results of SSBD are used to guide antibiotics adjustment | Chinese Medical Association | Severe Pneumonia | 06/25 | 06/25 | | |
NCT05709106: A Prospective Real World Study of Rimegepant in the Treatment of Migraine |
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| Recruiting | N/A | 100 | RoW | Rimegepant 75 MG | Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine | Migraine | 01/25 | 12/25 | | |
NCT05729217: Long COVID Symptoms in SARS-CoV-2-positive Children in China |
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| Active, not recruiting | N/A | 5000 | RoW | SBQ-LC survey | Tim Shi, Capital Institute of Pediatrics, China | Symptoms and Signs | 01/24 | 01/24 | | |
NCT05906719: Machine Vision Based MDS-UPDRS III Machine Rating |
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| Recruiting | N/A | 871 | RoW | video recording | Ruijin Hospital, Second Affiliated Hospital of Soochow University, Beijing Hospital, Beijing Tiantan Hospital, Wuhan Union Hospital, China, Fujian Medical University Union Hospital, Guangdong Provincial People's Hospital, West China Hospital | Parkinsonian Disorders, Machine Learning | 04/24 | 04/24 | | |
| Recruiting | N/A | 60 | RoW | intermittent theta burst stimulation, iTBS, sham iTBS | Ruijin Hospital | Neuroprotection, Parkinson Disease, Intermittent Theta Burst Stimulation | 06/24 | 12/24 | | |
SCORE, NCT05908955: Quantitative Superior Vena Cava Isolation in Addition to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation |
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| Recruiting | N/A | 290 | RoW | PVI, PVI+ quantitative SVCI | Chinese Academy of Medical Sciences, Fuwai Hospital | Atrial Fibrillation | 12/24 | 12/24 | | |
NCT06738862: [18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients |
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| Not yet recruiting | N/A | 35 | RoW | PET | Ruijin Hospital, National Natural Science Foundation of China | α-synucleinopathy, Parkinson's Disease (PD), Multiple System Atrophy, Rapid Eye Movement Sleep Behavior Disorder, PET | 12/24 | 11/25 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
NCT05336539: A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou |
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| Recruiting | N/A | 80000 | RoW | | Singlera Genomics Inc., Northern Jiangsu Province People's Hospital | Colorectal Cancer | 04/27 | 04/27 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
Chen, Xin |
OPTIMA-6, NCT05410925: Efficacy and Safety of a Half-dose Bolus of r-SAK Prior to Primary PCI in ST-elevation Myocardial Infarction |
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| Recruiting | 4 | 2260 | RoW | Recombinant staphylokinase, Placebo | The First Affiliated Hospital with Nanjing Medical University | ST Elevation Myocardial Infarction | 12/26 | 12/27 | | |
NCT05182463: Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients |
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| Recruiting | 4 | 5000 | RoW | Peginterferon Alfa-2B, Nucleoside Analogs | Third Affiliated Hospital, Sun Yat-Sen University | Hepatitis B, Chronic | 12/26 | 11/29 | | |
| Recruiting | 4 | 210 | RoW | Realgar Indigo naturalis formula, RIF, Conventional chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Zhujiang Hospital, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou First People's Hospital, Huizhou Municipal Central Hospital, First Affiliated Hospital of Shantou University Medical College, Zhongshan People's Hospital, Guangdong, China, Zhongshan Bo Ai Hospital, First Affiliated Hospital of Guangxi Medical University, LiuZhou People's Hospital, Second Xiangya Hospital of Central South University, Hainan People's Hospital | Arsenic Trioxide, Childhood ALL | 09/27 | 09/30 | | |
TQB2450-III-09, NCT04964479: A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus K Drug in the Treatment of First-line Non-small Cell Lung Cancer(NSCLC) |
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| Recruiting | 3 | 375 | RoW | TQB2450 injection, Anlotinib Hydrochloride Capsules, Pembrolizumab injection, Placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 12/22 | 03/23 | | |
NCT05003245: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD |
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| Recruiting | 3 | 388 | RoW | HLX04-O,recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection, Lucentis | Shanghai Henlius Biotech | Age Related Macular Degeneration | 08/23 | 03/24 | | |
NCT06301854: Long-term Safety of TPN171H Tablet in Erectile Dysfunction. |
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| Recruiting | 3 | 472 | RoW | TPN171H, Simmerafil | Vigonvita Life Sciences | Erectile Dysfunction | 04/25 | 04/25 | | |
NCT04937387: Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled Asthma |
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| Completed | 3 | 359 | RoW | FF/VI, FF/UMEC/VI, ELLIPTA | GlaxoSmithKline | Asthma | 08/24 | 08/24 | | |
| Recruiting | 2 | 30 | RoW | Mitoxantrone hydrochloride liposome, Venetoclax, Cytarabine,Cytosine arabinoside, Cyclophosphamide | Institute of Hematology & Blood Diseases Hospital, China | Relapse Acute Myeloid Leukemia | 05/27 | 10/27 | | |
| Recruiting | 1/2 | 60 | RoW | PM8002, nab-paclitaxel | Biotheus Inc. | TNBC | 10/26 | 10/26 | | |
NCT05001412: Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLC |
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| Recruiting | 1 | 36 | RoW | Camrelizumab; apatinib; carboplatin; etoposide | Zhou Chengzhi, Jiangsu Hengrui Pharmaceutical Co., Ltd. | Extensive Stage Small Cell Lung Cancer | 01/23 | 01/24 | | |
NCT04613115: Relationship Between Arterial Variations and Patency of Arteriovenous Fistulae |
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| Completed | N/A | 1000 | RoW | | Beijing Tongren Hospital | Arteriovenous Fistula, Ultrasound, Artery | 06/21 | 06/22 | | |
GIANT, NCT04765592: Guo's Aortic Arch Reconstruction :The Prospective ,Multiple Center Study About the Safety and Efficacy of WeFlow-Arch Modeler Embedded Branch Stent Graft System ( Study) |
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| Active, not recruiting | N/A | 88 | RoW | WeFlow-Arch Modeler Embedded Branch Stent Graft System | Hangzhou Endonom Medtech Co., Ltd. | Aortic Arch Aneurysm | 02/25 | 02/29 | | |
PLACARD, NCT06336239: PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study |
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| Recruiting | N/A | 3000 | RoW | | Beijing Anzhen Hospital | Cardiovascular Disease, Type 2 Diabetes Mellitus | 07/24 | 12/24 | | |
GRAFT, NCT05754541: Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study( Study) |
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| Recruiting | N/A | 20 | RoW | WeFlow-Tribranch Aortic Arch Stent Graft System | Hangzhou Endonom Medtech Co., Ltd. | Aortic Aneurysm and Dissection | 12/23 | 12/25 | | |
NCT05021601: Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atrial Fibrillation |
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| Recruiting | N/A | 320 | RoW | Bi-atrial ablation, Left atrial ablation | China National Center for Cardiovascular Diseases | Persistent Atrial Fibrillation | 06/25 | 07/25 | | |
NCT06385379: Guo's Aortic Arch Reconstruction: A Multicenter, Prospective Study of the Novel WeFlow-Tribranch System (GENIUS Study) |
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| Recruiting | N/A | 90 | RoW | WeFlow-Tribranch embedded aortic Triple-branch arch Stent Graft system | Hangzhou Endonom Medtech Co., Ltd. | Aortic Arch Aneurysm | 12/25 | 12/30 | | |
| Recruiting | N/A | 480 | RoW | Usual care, POST-strategy | Istituto Auxologico Italiano | Hypertension,Essential, Hypertension, Uncontrolled | 12/24 | 12/24 | | |
| Not yet recruiting | N/A | 2000 | RoW | | China-Japan Friendship Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, First Hospital of China Medical University, Henan Provincial People's Hospital, Second Xiangya Hospital of Central South University, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Sichuan University, Ruijin Hospital Affiliated to Shanghai Jiao Tong University, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China | Chronic Obstructive Pulmonary Disease (COPD), Asthma, Bronchiectasis | 07/28 | 07/28 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Active, not recruiting | N/A | 255 | RoW | EDWARDS INSPIRIS RESILIA Aortic Valve | Edwards Lifesciences, Edwards (Shanghai) Lifesciences Medical Supplies Co., Ltd., Rundo International Pharmaceutical Research & Development Co.,Ltd., Fuwai Hospital, CAMS & PUMC | Aortic Valve Replacement | 12/28 | 12/29 | | |
NCT05376618: Pilot Study on Proteomics of Erythrocyte Proteins in Patients With COPD Based on TMT Technology |
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| Completed | N/A | 30 | RoW | no intervention | Zhujiang Hospital | Protein; Disease | 07/22 | 07/22 | | |